JP2021525509A5 - - Google Patents
Info
- Publication number
- JP2021525509A5 JP2021525509A5 JP2020566230A JP2020566230A JP2021525509A5 JP 2021525509 A5 JP2021525509 A5 JP 2021525509A5 JP 2020566230 A JP2020566230 A JP 2020566230A JP 2020566230 A JP2020566230 A JP 2020566230A JP 2021525509 A5 JP2021525509 A5 JP 2021525509A5
- Authority
- JP
- Japan
- Prior art keywords
- receptor
- antigen
- protein
- cancer
- cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024039934A JP2024073564A (ja) | 2018-06-01 | 2024-03-14 | 細胞療法のための多様な抗原結合ドメイン、新規プラットフォームおよびその他の強化 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862679741P | 2018-06-01 | 2018-06-01 | |
| US62/679,741 | 2018-06-01 | ||
| PCT/US2019/035096 WO2019232503A1 (en) | 2018-06-01 | 2019-06-01 | Diverse antigen binding domains, novel platforms and other enhancements for cellular therapy |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024039934A Division JP2024073564A (ja) | 2018-06-01 | 2024-03-14 | 細胞療法のための多様な抗原結合ドメイン、新規プラットフォームおよびその他の強化 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021525509A JP2021525509A (ja) | 2021-09-27 |
| JP2021525509A5 true JP2021525509A5 (enExample) | 2022-06-07 |
| JP7599205B2 JP7599205B2 (ja) | 2024-12-13 |
Family
ID=68697132
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020566230A Active JP7599205B2 (ja) | 2018-06-01 | 2019-06-01 | 細胞療法のための多様な抗原結合ドメイン、新規プラットフォームおよびその他の強化 |
| JP2024039934A Pending JP2024073564A (ja) | 2018-06-01 | 2024-03-14 | 細胞療法のための多様な抗原結合ドメイン、新規プラットフォームおよびその他の強化 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024039934A Pending JP2024073564A (ja) | 2018-06-01 | 2024-03-14 | 細胞療法のための多様な抗原結合ドメイン、新規プラットフォームおよびその他の強化 |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20210137977A1 (enExample) |
| EP (1) | EP3802822A4 (enExample) |
| JP (2) | JP7599205B2 (enExample) |
| KR (1) | KR20210057705A (enExample) |
| CN (1) | CN113286879B (enExample) |
| AU (2) | AU2019279084B2 (enExample) |
| BR (1) | BR112020024246A2 (enExample) |
| CA (1) | CA3101510A1 (enExample) |
| CO (1) | CO2020016586A2 (enExample) |
| EA (1) | EA202092945A1 (enExample) |
| IL (2) | IL317990A (enExample) |
| MX (1) | MX2020012927A (enExample) |
| SG (1) | SG11202011837UA (enExample) |
| TW (1) | TW202018083A (enExample) |
| WO (1) | WO2019232503A1 (enExample) |
| ZA (2) | ZA202007393B (enExample) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018225732A1 (ja) | 2017-06-05 | 2018-12-13 | 国立大学法人三重大学 | Ｍａｇｅ－ａ４由来ペプチドを認識する抗原結合性タンパク質 |
| WO2019067805A1 (en) | 2017-09-27 | 2019-04-04 | University Of Southern California | NEW PLATFORMS FOR CO-STIMULATION, NEW CAR DESIGNS AND OTHER IMPROVEMENTS FOR ADOPTIVE CELL THERAPY |
| UA128001C2 (uk) | 2018-12-21 | 2024-03-06 | Ф. Хоффманн-Ля Рош Аг | Націлені на пухлину агоністичні cd28-антигензв'язувальні молекули |
| EP3733707A1 (en) * | 2019-04-30 | 2020-11-04 | Celyad S.A. | Car t-cells targeting bcma and uses thereof |
| AU2020361622A1 (en) * | 2019-10-10 | 2022-04-28 | Arizona Board Of Regents On Behalf Of Arizona State University | Oncolytic viruses that express multi-specific immune cell engagers |
| EP3842461A1 (en) * | 2019-12-23 | 2021-06-30 | Albert-Ludwigs-Universität Freiburg | Chimeric antigen receptors that bind to prostate specific membrane antigen |
| CA3166832A1 (en) * | 2020-01-08 | 2021-07-15 | Board Of Regents, The University Of Texas Systems | A method of engineering natural killer cells to target cd70-positive tumors |
| CA3171906A1 (en) | 2020-03-16 | 2021-09-23 | University Of Southern California | Novel antigen binding domains and synthetic antigen receptors incorporating the same |
| JP2023522857A (ja) * | 2020-04-10 | 2023-06-01 | ジュノー セラピューティクス インコーポレイテッド | Ｂ細胞成熟抗原を標的とするキメラ抗原受容体によって操作された細胞療法に関する方法および使用 |
| BR112022021563A2 (pt) * | 2020-04-24 | 2022-12-27 | Memorial Sloan Kettering Cancer Center | Receptores de antígeno quimérico que alvejam cd19 e uso dos mesmos |
| TW202208412A (zh) * | 2020-05-06 | 2022-03-01 | 瑞士商Ｃｒｉｓｐｒ治療公司 | 對酪胺酸蛋白激酶樣７（ｐｔｋ７）特異的經掩蔽的嵌合抗原受體和表現其的免疫細胞 |
| WO2021231237A2 (en) * | 2020-05-11 | 2021-11-18 | Augmenta Bioworks, Inc. | Antibodies for sars-cov-2 and uses thereof |
| US20230357384A1 (en) * | 2020-06-18 | 2023-11-09 | Nextcure, Inc. | Compositions and methods for modulating flrt3 mediated signal transduction |
| EP4192864A4 (en) * | 2020-08-06 | 2024-09-04 | Stelexis Therapeutics, LLC | IL-8 ANTIBODIES AND METHODS OF USE THEREOF |
| EP4223775A4 (en) * | 2020-09-29 | 2025-07-30 | Kunming Sinoway Natural Pharmaceuticals Co Ltd | HUMANIZED RECOMBINANT ANTI-CD22 IMMUNOTOXIN AND ITS APPLICATION |
| EP4255936A4 (en) * | 2020-12-02 | 2025-01-22 | Shanghai AbelZeta Ltd. | Bcma-targeted chimeric antigen receptors |
| WO2022170126A2 (en) * | 2021-02-05 | 2022-08-11 | Adagio Therapeutics, Inc. | Compounds specific to coronavirus s protein and uses thereof |
| AU2022227021A1 (en) * | 2021-02-26 | 2023-09-21 | Kelonia Therapeutics, Inc. | Lymphocyte targeted lentiviral vectors |
| CN115491358B (zh) * | 2021-06-17 | 2024-09-06 | 复星凯特生物科技有限公司 | 一种靶向b7-h3和folr1双打靶点car t的制备及应用 |
| TW202330594A (zh) * | 2021-09-29 | 2023-08-01 | 美商莫德斯醫療公司 | 抗原結合多肽、抗原結合多肽複合物及其使用方法 |
| IL312204A (en) | 2021-10-28 | 2024-06-01 | Lyell Immunopharma Inc | Methods for culturing cells expressing ror1-binding protein |
| CN114106199B (zh) * | 2021-11-19 | 2022-07-12 | 广州百暨基因科技有限公司 | 靶向adgre2的嵌合抗原受体及其应用 |
| KR20240139065A (ko) * | 2022-02-07 | 2024-09-20 | 지앙수 헨그루이 파마슈티컬스 컴퍼니 리미티드 | Psma 및 cd3에 특이적으로 결합하는 항원 결합 분자 및 이들의 의약적 용도 |
| CA3253514A1 (en) * | 2022-03-07 | 2023-09-14 | Medimmune Llc | TREATMENT METHODS USING CTLA-4 AND PD-1 BISPECIFIC ANTIBODIES |
| WO2023175069A1 (en) * | 2022-03-16 | 2023-09-21 | Medigene Immunotherapies Gmbh | Tcr constant region pairing library for pramevld tcrs |
| WO2023175070A1 (en) * | 2022-03-16 | 2023-09-21 | Medigene Immunotherapies Gmbh | Tcr constant region pairing library |
| GB202208119D0 (en) * | 2022-06-01 | 2022-07-13 | Univ Oslo Hf | Anti-steap1 car |
| WO2024064952A1 (en) | 2022-09-23 | 2024-03-28 | Lyell Immunopharma, Inc. | Methods for culturing nr4a-deficient cells overexpressing c-jun |
| WO2024064958A1 (en) | 2022-09-23 | 2024-03-28 | Lyell Immunopharma, Inc. | Methods for culturing nr4a-deficient cells |
| WO2024077174A1 (en) | 2022-10-05 | 2024-04-11 | Lyell Immunopharma, Inc. | Methods for culturing nr4a-deficient cells |
| WO2024136899A1 (en) * | 2022-12-21 | 2024-06-27 | Synthorx, Inc. | Cancer therapy with il-2 conjugates and chimeric antigen receptor therapies |
| GB202301421D0 (en) * | 2023-02-01 | 2023-03-15 | Univ Oslo Hf | Switch receptor for use in adoptive cell therapy |
| KR20250131823A (ko) | 2023-03-31 | 2025-09-03 | 아벨제타 인크. | Cd20 및 bcma를 표적화하는 이중특이적 키메라 항원 수용체 |
| WO2024220834A1 (en) * | 2023-04-19 | 2024-10-24 | H. Lee Moffitt Cancer Center And Research Institute Inc. | Car-t cells co-expressing cd40l |
| WO2024243093A2 (en) * | 2023-05-19 | 2024-11-28 | The Regents Of The University Of California | Multispecific antibodies targeting cd3 and cd22 |
| AU2024353718A1 (en) | 2023-09-25 | 2026-04-09 | Kelonia Therapeutics, Inc. | Compositions for treating cancer |
| AU2024353243A1 (en) | 2023-09-25 | 2026-04-09 | Kelonia Therapeutics, Inc. | Antigen binding polypeptides |
| WO2025151607A1 (en) * | 2024-01-10 | 2025-07-17 | Santa Ana Bio, Inc. | Methods and compositions for treating autoimmune, allergic and inflammatory diseases |
| WO2025217398A1 (en) | 2024-04-10 | 2025-10-16 | Lyell Immunopharma, Inc. | Methods for culturing cells with improved culture medium |
| WO2025245381A1 (en) | 2024-05-23 | 2025-11-27 | The Trustrees Of Dartmouth College | Methods and compositions for enhancing the persistence of car expressing tregs in the cns and other tissues |
| WO2025257781A1 (en) * | 2024-06-14 | 2025-12-18 | Novartis Ag | Treatment of systemic sclerosis using anti-baff-r antibodies |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5703055A (en) | 1989-03-21 | 1997-12-30 | Wisconsin Alumni Research Foundation | Generation of antibodies through lipid mediated DNA delivery |
| US5399346A (en) | 1989-06-14 | 1995-03-21 | The United States Of America As Represented By The Department Of Health And Human Services | Gene therapy |
| US5731168A (en) | 1995-03-01 | 1998-03-24 | Genentech, Inc. | Method for making heteromultimeric polypeptides |
| EP1958962A3 (en) | 1997-06-12 | 2013-05-01 | Novartis International Pharmaceutical Ltd. | Artificial antibody polypeptides |
| GB9809658D0 (en) * | 1998-05-06 | 1998-07-01 | Celltech Therapeutics Ltd | Biological products |
| CN1294148C (zh) | 2001-04-11 | 2007-01-10 | 中国科学院遗传与发育生物学研究所 | 环状单链三特异抗体 |
| KR20060041205A (ko) | 2003-07-01 | 2006-05-11 | 이뮤노메딕스, 인코오포레이티드 | 양특이성 항체들의 다가 담체들 |
| EP1786918A4 (en) | 2004-07-17 | 2009-02-11 | Imclone Systems Inc | NEW BISPECIFIC ANTIBODY TETRAVALENT |
| WO2010085660A2 (en) * | 2009-01-23 | 2010-07-29 | Roger Williams Hospital | Viral vectors encoding multiple highly homologous non-viral polypeptides and the use of same |
| CA2832540C (en) | 2011-04-08 | 2020-09-15 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Anti-epidermal growth factor receptor variant iii chimeric antigen receptors and use of same for the treatment of cancer |
| WO2013033626A2 (en) * | 2011-08-31 | 2013-03-07 | Trustees Of Dartmouth College | Nkp30 receptor targeted therapeutics |
| PT2768942T (pt) | 2011-10-17 | 2020-01-21 | Massachusetts Inst Technology | Entrega intracelular |
| EP2970312B1 (en) | 2013-03-11 | 2017-11-15 | The Regents of The University of Michigan | Bet bromodomain inhibitors and therapeutic methods using the same |
| EP3404111A1 (en) | 2013-03-13 | 2018-11-21 | Health Research, Inc. | Compositions and methods for use of recombinant t cell receptors for direct recognition of tumor antigen |
| BR112016018100A2 (pt) | 2014-02-07 | 2018-02-20 | Univ Mcmaster | acoplador antigênico de células t trifuncional, métodos e usos do mesmo |
| EP3131927B8 (en) * | 2014-04-14 | 2020-12-23 | Cellectis | Bcma (cd269) specific chimeric antigen receptors for cancer immunotherapy |
| BR112017001183A2 (pt) * | 2014-07-21 | 2017-11-28 | Novartis Ag | tratamento de câncer usando receptor de antígeno quimérico anti-bcma humanizado |
| WO2016174852A1 (ja) * | 2015-04-30 | 2016-11-03 | 株式会社デンソー | 蒸発器 |
| PL3298033T5 (pl) | 2015-05-18 | 2023-10-30 | TCR2 Therapeutics Inc. | Kompozycje i zastosowania medyczne do reprogramowania TCR z zastosowaniem białek fuzyjnych |
| US11655452B2 (en) * | 2015-06-25 | 2023-05-23 | Icell Gene Therapeutics Inc. | Chimeric antigen receptors (CARs), compositions and methods of use thereof |
| MX2018004721A (es) * | 2015-10-23 | 2018-07-06 | Eureka Therapeutics Inc | Construcciones quimericas anticuerpo/receptor de celulas t y usos de las mismas. |
| KR20230148844A (ko) * | 2016-03-29 | 2023-10-25 | 유니버시티 오브 써던 캘리포니아 | 암을 표적하는 키메라 항원 수용체 |
| US11768203B2 (en) | 2016-03-31 | 2023-09-26 | University Of Southern California | Highly sensitive and specific luciferase based reporter assay for antigen detection |
| JP6940530B2 (ja) | 2016-06-30 | 2021-09-29 | イリノイ トゥール ワークス インコーポレイティド | 機器コンソールとしてのハードワイヤ接続されるタブレット／スマートフォン用のホルダー |
| EP3548055A4 (en) * | 2016-12-02 | 2020-08-19 | University of Southern California | SYNTHETIC IMMUNE RECEPTORS AND THEIR PROCESSES FOR USE |
| WO2019067805A1 (en) | 2017-09-27 | 2019-04-04 | University Of Southern California | NEW PLATFORMS FOR CO-STIMULATION, NEW CAR DESIGNS AND OTHER IMPROVEMENTS FOR ADOPTIVE CELL THERAPY |
| KR20230153529A (ko) * | 2021-02-19 | 2023-11-06 | 프리트 엠. 쇼드하리 | 다양한 면역세포를 위한 단일사슬 및 다중사슬 합성 항원 수용체 |
-
2019
- 2019-06-01 JP JP2020566230A patent/JP7599205B2/ja active Active
- 2019-06-01 WO PCT/US2019/035096 patent/WO2019232503A1/en not_active Ceased
- 2019-06-01 EA EA202092945A patent/EA202092945A1/ru unknown
- 2019-06-01 SG SG11202011837UA patent/SG11202011837UA/en unknown
- 2019-06-01 EP EP19811044.7A patent/EP3802822A4/en active Pending
- 2019-06-01 US US15/734,203 patent/US20210137977A1/en active Pending
- 2019-06-01 IL IL317990A patent/IL317990A/en unknown
- 2019-06-01 IL IL279100A patent/IL279100B2/en unknown
- 2019-06-01 CA CA3101510A patent/CA3101510A1/en active Pending
- 2019-06-01 AU AU2019279084A patent/AU2019279084B2/en active Active
- 2019-06-01 CN CN201980049331.5A patent/CN113286879B/zh active Active
- 2019-06-01 KR KR1020207038038A patent/KR20210057705A/ko active Pending
- 2019-06-01 BR BR112020024246-2A patent/BR112020024246A2/pt unknown
- 2019-06-01 MX MX2020012927A patent/MX2020012927A/es unknown
- 2019-06-03 TW TW108119201A patent/TW202018083A/zh unknown
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2020
- 2020-11-26 ZA ZA2020/07393A patent/ZA202007393B/en unknown
- 2020-12-29 CO CONC2020/0016586A patent/CO2020016586A2/es unknown
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2022
- 2022-05-23 ZA ZA2022/05644A patent/ZA202205644B/en unknown
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2024
- 2024-03-14 JP JP2024039934A patent/JP2024073564A/ja active Pending
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2025
- 2025-07-16 AU AU2025205493A patent/AU2025205493A1/en active Pending