JP2020517263A5 - - Google Patents

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Publication number
JP2020517263A5
JP2020517263A5 JP2019556956A JP2019556956A JP2020517263A5 JP 2020517263 A5 JP2020517263 A5 JP 2020517263A5 JP 2019556956 A JP2019556956 A JP 2019556956A JP 2019556956 A JP2019556956 A JP 2019556956A JP 2020517263 A5 JP2020517263 A5 JP 2020517263A5
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JP
Japan
Prior art keywords
receptor
antigen
cell
protein
cancer
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2019556956A
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English (en)
Japanese (ja)
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JP2020517263A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2018/028427 external-priority patent/WO2018195348A1/en
Publication of JP2020517263A publication Critical patent/JP2020517263A/ja
Publication of JP2020517263A5 publication Critical patent/JP2020517263A5/ja
Pending legal-status Critical Current

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JP2019556956A 2017-04-19 2018-04-19 がんを治療するための組成物及び方法 Pending JP2020517263A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762487358P 2017-04-19 2017-04-19
US62/487,358 2017-04-19
PCT/US2018/028427 WO2018195348A1 (en) 2017-04-19 2018-04-19 Compositions and methods for treating cancer

Publications (2)

Publication Number Publication Date
JP2020517263A JP2020517263A (ja) 2020-06-18
JP2020517263A5 true JP2020517263A5 (enExample) 2020-07-30

Family

ID=63856183

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2019556956A Pending JP2020517263A (ja) 2017-04-19 2018-04-19 がんを治療するための組成物及び方法

Country Status (6)

Country Link
US (1) US20210095029A1 (enExample)
EP (1) EP3612222A4 (enExample)
JP (1) JP2020517263A (enExample)
CN (1) CN110536700A (enExample)
AU (1) AU2018254517A1 (enExample)
WO (1) WO2018195348A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20210112310A (ko) * 2018-12-06 2021-09-14 광동 티씨알큐어 바이오파마 테크놀로지 씨오., 엘티디. 종양 항원, tgf-베타 및 면역체크포인트를 표적으로 하는 tcr-t 세포 복합 치료법
US12419913B2 (en) 2019-02-08 2025-09-23 Dna Twopointo, Inc. Modification of CAR-T cells
WO2020214957A1 (en) 2019-04-19 2020-10-22 Tcrcure Biopharma Corp. Anti-pd-1 antibodies and uses thereof
EP3999550A4 (en) 2019-07-17 2023-09-06 Legend Biotech USA Inc. ANTI-DLL3 CHIMERIC ANTIGEN RECEPTORS AND THEIR USES
WO2021155518A1 (en) * 2020-02-05 2021-08-12 Tcrcure Biopharma Corp Anti-hpv t cell receptors and engineered cells
TW202216768A (zh) 2020-06-22 2022-05-01 美商恩格姆生物製藥公司 Lair-1結合劑及其使用方法
CN111704675B (zh) * 2020-07-08 2022-05-10 武汉波睿达生物科技有限公司 一种治疗hiv感染的双特异性嵌合抗原受体、基因、构建方法及其应用
CN111826400A (zh) * 2020-07-21 2020-10-27 中科宝承生物医学科技有限公司 一种双特异性抗体nk细胞制备方法及其细胞和应用
CN114437229B (zh) * 2020-11-01 2024-03-12 复旦大学 携带pd-1単链抗体且靶向egfr抗原的car t免疫细胞的制备及其用途
TW202330909A (zh) * 2021-09-09 2023-08-01 大陸商深圳市菲鵬生物治療股份有限公司 轉基因免疫效應細胞、其製備方法、慢病毒、構建體、癌症治療藥物及其應用
CN115025217B (zh) * 2022-05-13 2023-05-05 广东齐美医药生物科技集团有限公司 干细胞裂解物联合活性多糖以及酪氨酸酶抑制剂在制备药物或化妆品中的用途
CN119286780B (zh) * 2024-12-12 2025-03-21 山东省成体细胞产业技术研究院有限公司 一种t细胞的体外培养方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20210108497A (ko) * 2013-02-26 2021-09-02 메모리얼 슬로안 케터링 캔서 센터 면역치료용 조성물 및 방법
WO2016126608A1 (en) * 2015-02-02 2016-08-11 Novartis Ag Car-expressing cells against multiple tumor antigens and uses thereof
WO2016172583A1 (en) * 2015-04-23 2016-10-27 Novartis Ag Treatment of cancer using chimeric antigen receptor and protein kinase a blocker
HK1254803A1 (zh) * 2015-06-23 2019-07-26 Memorial Sloan Kettering Cancer Center 新型pd -1的免疫调节剂
WO2017133175A1 (en) * 2016-02-04 2017-08-10 Nanjing Legend Biotech Co., Ltd. Engineered mammalian cells for cancer therapy
CN105796597A (zh) * 2016-03-11 2016-07-27 江苏三特生物科技有限公司 携带pd-l1和ctla-4抗体基因的car-t细胞在肿瘤免疫上的应用
EP3432924A1 (en) * 2016-03-23 2019-01-30 Novartis AG Cell secreted minibodies and uses thereof
CN107523547A (zh) * 2016-06-20 2017-12-29 上海细胞治疗研究院 一种高效稳定表达抑制性抗体的car‑t细胞及其用途

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