JP2023525720A5 - - Google Patents
Info
- Publication number
- JP2023525720A5 JP2023525720A5 JP2022567469A JP2022567469A JP2023525720A5 JP 2023525720 A5 JP2023525720 A5 JP 2023525720A5 JP 2022567469 A JP2022567469 A JP 2022567469A JP 2022567469 A JP2022567469 A JP 2022567469A JP 2023525720 A5 JP2023525720 A5 JP 2023525720A5
- Authority
- JP
- Japan
- Prior art keywords
- cancer
- receptor
- domain
- antigen
- cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063023191P | 2020-05-11 | 2020-05-11 | |
| US63/023,191 | 2020-05-11 | ||
| US202063133224P | 2020-12-31 | 2020-12-31 | |
| US63/133,224 | 2020-12-31 | ||
| PCT/US2021/031878 WO2021231505A1 (en) | 2020-05-11 | 2021-05-11 | Vectors and methods for in vivo transduction |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023525720A JP2023525720A (ja) | 2023-06-19 |
| JP2023525720A5 true JP2023525720A5 (enExample) | 2024-05-17 |
Family
ID=78524914
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022567469A Pending JP2023525720A (ja) | 2020-05-11 | 2021-05-11 | Ｉｎ ｖｉｖｏ形質導入のためのベクター及び方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20230304031A1 (enExample) |
| EP (1) | EP4149495A4 (enExample) |
| JP (1) | JP2023525720A (enExample) |
| KR (1) | KR20230010231A (enExample) |
| CN (1) | CN115968300A (enExample) |
| AU (1) | AU2021273253A1 (enExample) |
| CA (1) | CA3176697A1 (enExample) |
| IL (1) | IL297514A (enExample) |
| WO (1) | WO2021231505A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12351837B2 (en) | 2019-01-23 | 2025-07-08 | The Broad Institute, Inc. | Supernegatively charged proteins and uses thereof |
| WO2020191241A1 (en) | 2019-03-19 | 2020-09-24 | The Broad Institute, Inc. | Methods and compositions for editing nucleotide sequences |
| WO2020214842A1 (en) | 2019-04-17 | 2020-10-22 | The Broad Institute, Inc. | Adenine base editors with reduced off-target effects |
| CN116178567B (zh) * | 2022-10-28 | 2025-01-28 | 四川大学华西医院 | 一种靶向TGFβRII的嵌合抗原受体及其用途 |
| WO2024254346A1 (en) * | 2023-06-07 | 2024-12-12 | The Broad Institute, Inc. | Engineered viral like particles (evlps) for the selective transduction of target cells |
| WO2025033948A1 (ko) * | 2023-08-07 | 2025-02-13 | 마루테라퓨틱스 주식회사 | 유전자 고효율 발현이 가능한 비바이러스성 듀얼 플라스미드 벡터와 이를 발현하는 줄기세포 및 분화된 조혈계 세포 |
| CN116814664B (zh) * | 2023-08-25 | 2023-12-12 | 中国医学科学院肿瘤医院 | 一种扩展肿瘤识别表位的cea嵌合抗原受体t细胞的制备与应用 |
| CN116814595B (zh) * | 2023-08-30 | 2023-11-28 | 江苏申基生物科技有限公司 | 一种腺苷脱氨酶突变体及其固定化 |
| WO2026149447A1 (zh) * | 2025-01-07 | 2026-07-16 | 深圳市济因生物科技有限公司 | 一种颗粒及其应用 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5693508A (en) * | 1994-11-08 | 1997-12-02 | Chang; Lung-Ji | Retroviral expression vectors containing MoMLV/CMV-IE/HIV-TAR chimeric long terminal repeats |
| US5681746A (en) * | 1994-12-30 | 1997-10-28 | Chiron Viagene, Inc. | Retroviral delivery of full length factor VIII |
| US7001733B1 (en) * | 1998-05-12 | 2006-02-21 | Rigel Pharmaceuticals, Inc. | Methods and compositions for screening for modulations of IgE synthesis, secretion and switch rearrangement |
| WO2001091802A1 (en) * | 2000-05-30 | 2001-12-06 | Baylor College Of Medicine | Chimeric viral vectors for gene therapy |
| CN1860232A (zh) * | 2003-09-30 | 2006-11-08 | 莱克康遗传公司 | 鉴别基因功能的方法和组合物 |
| WO2009114725A2 (en) * | 2008-03-12 | 2009-09-17 | Children's Hospital Medical Center | Mobilization of hematopoietic stem cells |
| US20110098346A1 (en) * | 2008-05-19 | 2011-04-28 | Agency For Science, Technology And Research | Nucleic acid molecule and method of targeting gene expression to gliomas |
| EP2294218A2 (en) * | 2008-06-02 | 2011-03-16 | New York University | Compositions and methods for diagnosis, prognosis and treatment of mesothelioma |
| US20110020814A1 (en) * | 2009-06-05 | 2011-01-27 | Ipierian, Inc. | Methods and compositions for selection of stem cells |
| EP3546583A1 (en) * | 2009-06-17 | 2019-10-02 | Tocagen Inc. | Producer cells for replication competent retroviral vectors |
| US9839696B2 (en) * | 2010-04-30 | 2017-12-12 | City Of Hope | Recombinant adeno-associated vectors for targeted treatment |
| US9642921B2 (en) * | 2012-12-20 | 2017-05-09 | Tocagen Inc. | Cancer combination therapy and recombinant vectors |
| CA2912389C (en) * | 2013-06-10 | 2020-01-28 | The General Hospital Corporation D/B/A Massachusetts General Hospital | Methods and compositions for reducing immunosupression by tumor cells |
| JP2016526920A (ja) * | 2013-08-05 | 2016-09-08 | トカジェン インコーポレーテッド | 最適化ａ−バルジを有する組換えベクター |
| US10383929B2 (en) * | 2014-12-12 | 2019-08-20 | Bluebird Bio, Inc. | BCMA chimeric antigen receptors |
| AU2016317936A1 (en) * | 2015-09-04 | 2018-03-08 | Tocagen Inc. | Recombinant vectors comprising 2A peptide |
| CN108884460B (zh) * | 2016-03-19 | 2023-04-28 | 埃克苏马生物技术公司 | 淋巴细胞转导及其扩增调节的方法与组合物 |
| US11111505B2 (en) * | 2016-03-19 | 2021-09-07 | Exuma Biotech, Corp. | Methods and compositions for transducing lymphocytes and regulating the activity thereof |
| CA3030003A1 (en) * | 2016-07-08 | 2018-01-11 | F1 Oncology, Inc. | Methods and compositions for transducing lymphocytes and regulating the activity thereof |
| DK3612624T3 (da) * | 2017-04-21 | 2024-12-09 | Ospedale San Raffaele Srl | Genterapi |
| US20180327857A1 (en) * | 2017-05-09 | 2018-11-15 | Shanghai Realgen Biotech Co., Ltd. | Diagnostic biomarker and diagnostic method |
| WO2019025800A1 (en) * | 2017-08-02 | 2019-02-07 | Autolus Limited | CELLS EXPRESSING A CHIMERIC ANTIGENIC RECEPTOR OR A MANIPULATED TCR AND COMPRISING A SELECTIVELY EXPRESSED SELECTIVE NUCLEOTIDE SEQUENCE |
| KR20210063348A (ko) * | 2018-08-28 | 2021-06-01 | 이뮤노테크 바이오팜 씨오., 엘티디. | 개선된 치료용 t 세포 |
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2021
- 2021-05-11 CA CA3176697A patent/CA3176697A1/en active Pending
- 2021-05-11 CN CN202180048754.2A patent/CN115968300A/zh active Pending
- 2021-05-11 US US17/924,080 patent/US20230304031A1/en active Pending
- 2021-05-11 KR KR1020227043191A patent/KR20230010231A/ko not_active Ceased
- 2021-05-11 IL IL297514A patent/IL297514A/en unknown
- 2021-05-11 EP EP21803598.8A patent/EP4149495A4/en not_active Withdrawn
- 2021-05-11 JP JP2022567469A patent/JP2023525720A/ja active Pending
- 2021-05-11 WO PCT/US2021/031878 patent/WO2021231505A1/en not_active Ceased
- 2021-05-11 AU AU2021273253A patent/AU2021273253A1/en not_active Abandoned