JP2021532742A5 - - Google Patents

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Publication number
JP2021532742A5
JP2021532742A5 JP2021504286A JP2021504286A JP2021532742A5 JP 2021532742 A5 JP2021532742 A5 JP 2021532742A5 JP 2021504286 A JP2021504286 A JP 2021504286A JP 2021504286 A JP2021504286 A JP 2021504286A JP 2021532742 A5 JP2021532742 A5 JP 2021532742A5
Authority
JP
Japan
Prior art keywords
nef
domain
tcr
cells
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2021504286A
Other languages
English (en)
Japanese (ja)
Other versions
JP2021532742A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/CN2019/097969 external-priority patent/WO2020020359A1/en
Publication of JP2021532742A publication Critical patent/JP2021532742A/ja
Publication of JP2021532742A5 publication Critical patent/JP2021532742A5/ja
Pending legal-status Critical Current

Links

JP2021504286A 2018-07-26 2019-07-26 Nefを含むt細胞及びその生成方法 Pending JP2021532742A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN2018097235 2018-07-26
CNPCT/CN2018/097235 2018-07-26
PCT/CN2019/097969 WO2020020359A1 (en) 2018-07-26 2019-07-26 Nef-containing t cells and methods of producing thereof

Publications (2)

Publication Number Publication Date
JP2021532742A JP2021532742A (ja) 2021-12-02
JP2021532742A5 true JP2021532742A5 (enExample) 2022-07-06

Family

ID=69181353

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021504286A Pending JP2021532742A (ja) 2018-07-26 2019-07-26 Nefを含むt細胞及びその生成方法

Country Status (12)

Country Link
US (1) US20220177524A1 (enExample)
EP (1) EP3827075A4 (enExample)
JP (1) JP2021532742A (enExample)
KR (1) KR20210049806A (enExample)
CN (2) CN112771154B (enExample)
AU (1) AU2019312411A1 (enExample)
CA (1) CA3103337A1 (enExample)
IL (1) IL280240A (enExample)
MX (1) MX2021000934A (enExample)
SG (1) SG11202012253WA (enExample)
TW (1) TW202020146A (enExample)
WO (1) WO2020020359A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9273283B2 (en) * 2009-10-29 2016-03-01 The Trustees Of Dartmouth College Method of producing T cell receptor-deficient T cells expressing a chimeric receptor
CN115768899B (zh) * 2020-03-09 2026-03-27 詹森生物科技公司 用于定量重组载体核酸整合的组合物和方法
WO2022116086A1 (en) * 2020-12-03 2022-06-09 Janssen Biotech, Inc. Bcma-targeted car-t cell therapy for multiple myeloma
EP4259784A4 (en) * 2020-12-14 2025-01-15 Nanjing Legend Biotech Co., Ltd. METHODS AND COMPOSITIONS FOR DEPOVERY OF NATURAL KILLER CELLS AND USES THEREOF IN CELLULAR THERAPIES
CA3207206A1 (en) * 2021-02-01 2022-08-04 Lingfeng LIU Targeted protein degradation system and use thereof
CN117396498A (zh) * 2021-03-18 2024-01-12 威斯塔解剖学和生物学研究所 靶向IL13Rα2的DNA编码的双特异性抗体以及在癌症治疗中的使用方法
JP2024528077A (ja) * 2021-07-30 2024-07-26 ▲い▼尊生物医薬(浙江)有限公司 汎用型t細胞およびその応用
JP2024540275A (ja) * 2021-11-04 2024-10-31 ヤンセン バイオテック, インク. Bcmaを標的とする、多発性骨髄腫のためのcar-t細胞療法関連出願の相互参照
WO2023077343A1 (en) * 2021-11-04 2023-05-11 Janssen Biotech, Inc. Bcma-targeted car-t cell therapy for multiple myeloma
JP2025524921A (ja) * 2022-07-29 2025-08-01 レジェンド バイオテック アイルランド リミテッド 細胞療法の持続性を促進するための方法
WO2024098037A1 (en) * 2022-11-04 2024-05-10 WUGEN, Inc. Generation of cd3 expressing immune cells for use in conjunction with cd3 binding bispecific targeting agents
WO2024153211A1 (en) * 2023-01-19 2024-07-25 Nanjing Legend Biotech Co., Ltd. Fusion polypeptides for targeted protein degradation and mehtods of use thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1409694A4 (en) * 2001-07-05 2006-02-08 Chiron Corp POLYNUCLEOTIDES ENCODING ANTIGENIC POLYPEPTIDES OF HIV SUBTYPE B AND / OR SUBTYPE C, POLYPEPTIDES AND USES THEREOF
EP2420248A1 (en) * 2004-08-17 2012-02-22 Institut Gustave Roussy Mutated HIV NEF for modulating immunity
US9273283B2 (en) * 2009-10-29 2016-03-01 The Trustees Of Dartmouth College Method of producing T cell receptor-deficient T cells expressing a chimeric receptor
SG10201806573TA (en) * 2012-05-25 2018-09-27 Cellectis Methods for engineering allogeneic and immunosuppressive resistant t cell for immunotherapy
ES2959480T3 (es) * 2014-02-07 2024-02-26 Univ Mcmaster Acoplador de células T - antígeno trifuncional y métodos y usos del mismo
WO2015164759A2 (en) * 2014-04-25 2015-10-29 Bluebird Bio, Inc. Mnd promoter chimeric antigen receptors
BR112018014585A2 (pt) * 2016-01-21 2018-12-11 Pfizer receptores de antígeno quiméricos que direcionam o receptor do fator de crescimento epidérmico variante iii
AU2017248259A1 (en) * 2016-04-07 2018-10-25 Bluebird Bio, Inc. Chimeric antigen receptor T cell compositions
AU2017326748A1 (en) * 2016-09-14 2019-04-11 Benitec Biopharma Limited Reagents for producing T-cells with non-functional T-cell receptors (TCRs) compositions comprising same and use thereof
EP4759318A2 (en) * 2017-04-14 2026-06-17 The General Hospital Corporation Chimeric antigen receptor t cells targeting the tumor microenvironment
CN110520196A (zh) * 2017-04-19 2019-11-29 艾洛基治疗公司 改进的t细胞组合物和方法

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