JP2021532742A5 - - Google Patents

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Publication number
JP2021532742A5
JP2021532742A5 JP2021504286A JP2021504286A JP2021532742A5 JP 2021532742 A5 JP2021532742 A5 JP 2021532742A5 JP 2021504286 A JP2021504286 A JP 2021504286A JP 2021504286 A JP2021504286 A JP 2021504286A JP 2021532742 A5 JP2021532742 A5 JP 2021532742A5
Authority
JP
Japan
Prior art keywords
nef
domain
tcr
cells
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2021504286A
Other languages
English (en)
Japanese (ja)
Other versions
JP2021532742A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/CN2019/097969 external-priority patent/WO2020020359A1/en
Publication of JP2021532742A publication Critical patent/JP2021532742A/ja
Publication of JP2021532742A5 publication Critical patent/JP2021532742A5/ja
Pending legal-status Critical Current

Links

JP2021504286A 2018-07-26 2019-07-26 Nefを含むt細胞及びその生成方法 Pending JP2021532742A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CNPCT/CN2018/097235 2018-07-26
CN2018097235 2018-07-26
PCT/CN2019/097969 WO2020020359A1 (en) 2018-07-26 2019-07-26 Nef-containing t cells and methods of producing thereof

Publications (2)

Publication Number Publication Date
JP2021532742A JP2021532742A (ja) 2021-12-02
JP2021532742A5 true JP2021532742A5 (enExample) 2022-07-06

Family

ID=69181353

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021504286A Pending JP2021532742A (ja) 2018-07-26 2019-07-26 Nefを含むt細胞及びその生成方法

Country Status (12)

Country Link
US (1) US20220177524A1 (enExample)
EP (1) EP3827075A4 (enExample)
JP (1) JP2021532742A (enExample)
KR (1) KR20210049806A (enExample)
CN (2) CN112771154B (enExample)
AU (1) AU2019312411A1 (enExample)
CA (1) CA3103337A1 (enExample)
IL (1) IL280240A (enExample)
MX (1) MX2021000934A (enExample)
SG (1) SG11202012253WA (enExample)
TW (1) TW202020146A (enExample)
WO (1) WO2020020359A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9273283B2 (en) * 2009-10-29 2016-03-01 The Trustees Of Dartmouth College Method of producing T cell receptor-deficient T cells expressing a chimeric receptor
IL296319A (en) * 2020-03-09 2022-11-01 Janssen Biotech Inc Compositions and Methods for Quantifying Recombinant Vector Nucleic Acid Incorporation
WO2022116086A1 (en) * 2020-12-03 2022-06-09 Janssen Biotech, Inc. Bcma-targeted car-t cell therapy for multiple myeloma
WO2022161502A1 (zh) * 2021-02-01 2022-08-04 羿尊生物医药(浙江)有限公司 一种靶向蛋白降解系统及其应用
WO2022198027A1 (en) * 2021-03-18 2022-09-22 The Wistar Institute Of Anatomy And Biology DNA-ENCODED BISPECIFIC ANTIBODIES TARGETING IL13Rα2 AND METHODS OF USE IN CANCER THERAPEUTICS
KR20240042483A (ko) * 2021-07-30 2024-04-02 에쓰티 피에이치아이 테라퓨틱스 컴퍼니 리미티드 범용성 t 세포 및 이의 응용
IL312602A (en) * 2021-11-04 2024-07-01 Janssen Biotech Inc Bcma-targeted car-t cell therapy for multiple myeloma
WO2023077343A1 (en) * 2021-11-04 2023-05-11 Janssen Biotech, Inc. Bcma-targeted car-t cell therapy for multiple myeloma
WO2024022509A1 (en) * 2022-07-29 2024-02-01 Nanjing Legend Biotech Co., Ltd. Methods for promoting persistence of cell therapy
WO2024098037A1 (en) * 2022-11-04 2024-05-10 WUGEN, Inc. Generation of cd3 expressing immune cells for use in conjunction with cd3 binding bispecific targeting agents
WO2024153211A1 (en) * 2023-01-19 2024-07-25 Nanjing Legend Biotech Co., Ltd. Fusion polypeptides for targeted protein degradation and mehtods of use thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2280074A3 (en) * 2001-07-05 2011-06-22 Novartis Vaccines and Diagnostics, Inc. Polynucleotides encoding antigenic HIV type B and/or type C polypeptides, polypeptides and uses thereof
BRPI0514447B8 (pt) * 2004-08-17 2021-05-25 Centre Nat Rech Scient uso da função imunosupressora de uma proteína acessória do vírus da imunodeficiência humana ou do símio para a preparação de uma vacina
US9273283B2 (en) * 2009-10-29 2016-03-01 The Trustees Of Dartmouth College Method of producing T cell receptor-deficient T cells expressing a chimeric receptor
BR112014029417B1 (pt) * 2012-05-25 2023-03-07 Cellectis Método ex vivo para a preparação de células t para imunoterapia
BR112016018100A2 (pt) * 2014-02-07 2018-02-20 Univ Mcmaster acoplador antigênico de células t trifuncional, métodos e usos do mesmo
PL3134432T3 (pl) * 2014-04-25 2020-10-19 Bluebird Bio, Inc. Promotor mnd chimeryczne receptory antygenowe
TWI755547B (zh) * 2016-01-21 2022-02-21 美商輝瑞股份有限公司 靶向表皮生長因子受體變異體iii之嵌合型抗原受體
US20190161530A1 (en) * 2016-04-07 2019-05-30 Bluebird Bio, Inc. Chimeric antigen receptor t cell compositions
US20190309307A1 (en) * 2016-09-14 2019-10-10 Benitec Biopharma Limited REAGENTS FOR PRODUCING T-CELLS WITH NON-FUNCTIONAL T-CELL RECEPTORS (TCRs) COMPOSITIONS COMPRISING SAME AND USE THEREOF
US12378297B2 (en) * 2017-04-14 2025-08-05 The General Hospital Corporation Chimeric antigen receptor T cells targeting the tumor microenvironment
CN110520196A (zh) * 2017-04-19 2019-11-29 艾洛基治疗公司 改进的t细胞组合物和方法

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