TW202020146A - 含nef之t細胞及其產生方法 - Google Patents

含nef之t細胞及其產生方法 Download PDF

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TW202020146A
TW202020146A TW108126647A TW108126647A TW202020146A TW 202020146 A TW202020146 A TW 202020146A TW 108126647 A TW108126647 A TW 108126647A TW 108126647 A TW108126647 A TW 108126647A TW 202020146 A TW202020146 A TW 202020146A
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nef
tcr
mutant
domain
cell
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TW108126647A
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English (en)
Chinese (zh)
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曉虎 范
趙云程
俞大偉
支武吉南
王趁趁
莊秋傳
王平豔
郭璇璇
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大陸商南京傳奇生物科技有限公司
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    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
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    • C07K16/2878—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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    • C07K16/2887—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
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    • C07K2319/00—Fusion polypeptide
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    • C12N2740/10011—Retroviridae
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TW108126647A 2018-07-26 2019-07-26 含nef之t細胞及其產生方法 TW202020146A (zh)

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WOPCT/CN2018/097235 2018-07-26
CN2018097235 2018-07-26

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US (1) US20220177524A1 (enExample)
EP (1) EP3827075A4 (enExample)
JP (1) JP2021532742A (enExample)
KR (1) KR20210049806A (enExample)
CN (2) CN112771154B (enExample)
AU (1) AU2019312411A1 (enExample)
CA (1) CA3103337A1 (enExample)
IL (1) IL280240A (enExample)
MX (1) MX2021000934A (enExample)
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US9273283B2 (en) * 2009-10-29 2016-03-01 The Trustees Of Dartmouth College Method of producing T cell receptor-deficient T cells expressing a chimeric receptor
IL296319A (en) * 2020-03-09 2022-11-01 Janssen Biotech Inc Compositions and Methods for Quantifying Recombinant Vector Nucleic Acid Incorporation
WO2022116086A1 (en) * 2020-12-03 2022-06-09 Janssen Biotech, Inc. Bcma-targeted car-t cell therapy for multiple myeloma
WO2022161502A1 (zh) * 2021-02-01 2022-08-04 羿尊生物医药（浙江）有限公司 一种靶向蛋白降解系统及其应用
WO2022198027A1 (en) * 2021-03-18 2022-09-22 The Wistar Institute Of Anatomy And Biology DNA-ENCODED BISPECIFIC ANTIBODIES TARGETING IL13Rα2 AND METHODS OF USE IN CANCER THERAPEUTICS
KR20240042483A (ko) * 2021-07-30 2024-04-02 에쓰티 피에이치아이 테라퓨틱스 컴퍼니 리미티드 범용성 t 세포 및 이의 응용
IL312602A (en) * 2021-11-04 2024-07-01 Janssen Biotech Inc Bcma-targeted car-t cell therapy for multiple myeloma
WO2023077343A1 (en) * 2021-11-04 2023-05-11 Janssen Biotech, Inc. Bcma-targeted car-t cell therapy for multiple myeloma
WO2024022509A1 (en) * 2022-07-29 2024-02-01 Nanjing Legend Biotech Co., Ltd. Methods for promoting persistence of cell therapy
WO2024098037A1 (en) * 2022-11-04 2024-05-10 WUGEN, Inc. Generation of cd3 expressing immune cells for use in conjunction with cd3 binding bispecific targeting agents
WO2024153211A1 (en) * 2023-01-19 2024-07-25 Nanjing Legend Biotech Co., Ltd. Fusion polypeptides for targeted protein degradation and mehtods of use thereof

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EP2280074A3 (en) * 2001-07-05 2011-06-22 Novartis Vaccines and Diagnostics, Inc. Polynucleotides encoding antigenic HIV type B and/or type C polypeptides, polypeptides and uses thereof
BRPI0514447B8 (pt) * 2004-08-17 2021-05-25 Centre Nat Rech Scient uso da função imunosupressora de uma proteína acessória do vírus da imunodeficiência humana ou do símio para a preparação de uma vacina
US9273283B2 (en) * 2009-10-29 2016-03-01 The Trustees Of Dartmouth College Method of producing T cell receptor-deficient T cells expressing a chimeric receptor
BR112014029417B1 (pt) * 2012-05-25 2023-03-07 Cellectis Método ex vivo para a preparação de células t para imunoterapia
BR112016018100A2 (pt) * 2014-02-07 2018-02-20 Univ Mcmaster acoplador antigênico de células t trifuncional, métodos e usos do mesmo
PL3134432T3 (pl) * 2014-04-25 2020-10-19 Bluebird Bio, Inc. Promotor mnd chimeryczne receptory antygenowe
TWI755547B (zh) * 2016-01-21 2022-02-21 美商輝瑞股份有限公司 靶向表皮生長因子受體變異體iii之嵌合型抗原受體
US20190161530A1 (en) * 2016-04-07 2019-05-30 Bluebird Bio, Inc. Chimeric antigen receptor t cell compositions
US20190309307A1 (en) * 2016-09-14 2019-10-10 Benitec Biopharma Limited REAGENTS FOR PRODUCING T-CELLS WITH NON-FUNCTIONAL T-CELL RECEPTORS (TCRs) COMPOSITIONS COMPRISING SAME AND USE THEREOF
US12378297B2 (en) * 2017-04-14 2025-08-05 The General Hospital Corporation Chimeric antigen receptor T cells targeting the tumor microenvironment
CN110520196A (zh) * 2017-04-19 2019-11-29 艾洛基治疗公司 改进的t细胞组合物和方法

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KR20210049806A (ko) 2021-05-06
EP3827075A1 (en) 2021-06-02
CN119661659A (zh) 2025-03-21
CA3103337A1 (en) 2020-01-30
MX2021000934A (es) 2021-05-27
CN112771154B (zh) 2025-01-03
WO2020020359A1 (en) 2020-01-30
US20220177524A1 (en) 2022-06-09
IL280240A (en) 2021-03-25
JP2021532742A (ja) 2021-12-02
AU2019312411A1 (en) 2021-01-07
EP3827075A4 (en) 2022-08-03
SG11202012253WA (en) 2021-01-28
CN112771154A (zh) 2021-05-07

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