JP2021521116A5 - - Google Patents

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Publication number
JP2021521116A5
JP2021521116A5 JP2020554896A JP2020554896A JP2021521116A5 JP 2021521116 A5 JP2021521116 A5 JP 2021521116A5 JP 2020554896 A JP2020554896 A JP 2020554896A JP 2020554896 A JP2020554896 A JP 2020554896A JP 2021521116 A5 JP2021521116 A5 JP 2021521116A5
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JP
Japan
Prior art keywords
compound
group
salts
effective amount
tropolone
Prior art date
Application number
JP2020554896A
Other languages
English (en)
Japanese (ja)
Other versions
JP2021521116A (ja
JP7503310B2 (ja
JPWO2019200314A5 (https=
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Priority claimed from PCT/US2019/027314 external-priority patent/WO2019200314A2/en
Publication of JP2021521116A publication Critical patent/JP2021521116A/ja
Publication of JPWO2019200314A5 publication Critical patent/JPWO2019200314A5/ja
Publication of JP2021521116A5 publication Critical patent/JP2021521116A5/ja
Application granted granted Critical
Publication of JP7503310B2 publication Critical patent/JP7503310B2/ja
Active legal-status Critical Current
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JP2020554896A 2018-04-13 2019-04-12 ヒノキチオール類似体、それらの調製方法及び医薬組成物 Active JP7503310B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862657127P 2018-04-13 2018-04-13
US62/657,127 2018-04-13
PCT/US2019/027314 WO2019200314A2 (en) 2018-04-13 2019-04-12 Hinokitiol analogues, methods of preparing and pharmaceutical compositions thereof

Publications (4)

Publication Number Publication Date
JP2021521116A JP2021521116A (ja) 2021-08-26
JPWO2019200314A5 JPWO2019200314A5 (https=) 2022-04-15
JP2021521116A5 true JP2021521116A5 (https=) 2022-04-15
JP7503310B2 JP7503310B2 (ja) 2024-06-20

Family

ID=68163807

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020554896A Active JP7503310B2 (ja) 2018-04-13 2019-04-12 ヒノキチオール類似体、それらの調製方法及び医薬組成物

Country Status (8)

Country Link
US (1) US12084411B2 (https=)
EP (1) EP3773900A4 (https=)
JP (1) JP7503310B2 (https=)
KR (2) KR20260011772A (https=)
CN (1) CN112672786A (https=)
AU (2) AU2019252933B2 (https=)
CA (1) CA3095945A1 (https=)
WO (1) WO2019200314A2 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2019252933B2 (en) 2018-04-13 2025-09-04 The Board Of Trustees Of The University Of Illinois Hinokitiol analogues, methods of preparing and pharmaceutical compositions thereof
EP4045025A4 (en) * 2019-10-16 2023-11-22 Kinesid Therapeutics, Inc. TROPOLONE DERIVATIVES AND THEIR TAUTOMERS FOR IRON REGULATION IN ANIMALS
US20230406803A1 (en) * 2019-10-16 2023-12-21 Kinesid Therapeutics, Inc Tropolone derivatives and tautomers thereof for iron regulation in animals
CN114436909B (zh) * 2022-01-26 2023-05-30 河南科技大学 一种磺酰基桧木醇类衍生物及其制备方法和应用
CN115093356B (zh) * 2022-06-21 2024-02-23 广东医科大学 一种铁死亡诱导剂的制备方法与应用
JP2025531628A (ja) * 2022-09-30 2025-09-22 ザ ボード オブ トラスティーズ オブ ザ ユニヴァーシティ オブ イリノイ 神経変性疾患の処置方法
CN120282778A (zh) * 2022-09-30 2025-07-08 伊利诺伊大学评议会 氘化扁柏酚衍生物
CN117547525A (zh) * 2023-12-29 2024-02-13 中国科学院长春应用化学研究所 天然产物小分子桧木醇在制备治疗非酒精性脂肪性肝炎药物中的应用

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4066784A (en) 1976-06-17 1978-01-03 Ayerst, Mckenna And Harrison Ltd. Tropone derivatives
US4183955A (en) 1976-06-17 1980-01-15 Ayerst. McKenna & Harrison Limited Troponyl-oxamic acid derivatives for treating allergic conditions
JP2552870B2 (ja) * 1986-08-21 1996-11-13 塩野義製薬株式会社 抗マイコプラズマ剤および抗マイコプラズマ活性を有する化合物
JP2622836B2 (ja) * 1987-02-04 1997-06-25 富士写真フイルム株式会社 メチン色素
JPH02237964A (ja) 1989-03-13 1990-09-20 Nippon Shokubai Kagaku Kogyo Co Ltd トロポロン誘導体
AU2001258829A1 (en) * 2000-05-25 2001-12-03 Nippon Shinyaku Co. Ltd. Tropolone derivatives and pharmaceutical compositions
CN1247511C (zh) * 2000-12-26 2006-03-29 财团法人乙卯研究所 环庚三烯酚酮衍生物
JP2004238291A (ja) * 2003-02-03 2004-08-26 Osaka Organic Chem Ind Ltd 白血病細胞増殖阻害剤
US20100152301A1 (en) 2005-12-01 2010-06-17 Government Of The Us, As Represented By The Secretary, Department Of Health And Human Services Treatment of Viral Infections
JP2008158060A (ja) 2006-12-21 2008-07-10 Kyocera Mita Corp 電子写真感光体
JP5948139B2 (ja) * 2012-05-11 2016-07-06 ヒノキ新薬株式会社 サーチュイン1(sirt1)遺伝子活性化剤
JP2015526396A (ja) * 2012-06-22 2015-09-10 ユニバーシティ オブ コネチカット 置換トロポロン誘導体およびその使用方法
WO2016112381A1 (en) * 2015-01-09 2016-07-14 The Board Of Trustees Of The University Of Illinois Restoring physiology in iron-deficient organisms using small molecules
WO2017156194A1 (en) 2016-03-08 2017-09-14 The Regents Of The University Of California Compositions and methods for inhibiting influenza rna polymerase pa endonuclease
US10980754B2 (en) * 2016-04-19 2021-04-20 Saint Louis University Anti-fungal compounds
AU2019252933B2 (en) 2018-04-13 2025-09-04 The Board Of Trustees Of The University Of Illinois Hinokitiol analogues, methods of preparing and pharmaceutical compositions thereof

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