JP2021508235A5 - - Google Patents

Info

Publication number

JP2021508235A5

JP2021508235A5 JP2020526562A JP2020526562A JP2021508235A5 JP 2021508235 A5 JP2021508235 A5 JP 2021508235A5 JP 2020526562 A JP2020526562 A JP 2020526562A JP 2020526562 A JP2020526562 A JP 2020526562A JP 2021508235 A5 JP2021508235 A5 JP 2021508235A5

Authority

JP

Japan

Prior art keywords

paenibacillus

polypeptide

nucleic acid

fusion protein

signal peptide

Prior art date

2018-11-15

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Pending

Links

• Espacenet
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• 241000179039 Paenibacillus Species 0.000 claims 25
• 229920001184 polypeptide Polymers 0.000 claims 18
• 108090000765 processed proteins & peptides Proteins 0.000 claims 18
• 102000004196 processed proteins & peptides Human genes 0.000 claims 18
• 108020001507 fusion proteins Proteins 0.000 claims 13
• 102000037865 fusion proteins Human genes 0.000 claims 13
• 108020004707 nucleic acids Proteins 0.000 claims 13
• 102000039446 nucleic acids Human genes 0.000 claims 13
• 150000007523 nucleic acids Chemical class 0.000 claims 13
• 108010076504 Protein Sorting Signals Proteins 0.000 claims 12
• 108090000623 proteins and genes Proteins 0.000 claims 12
• 210000004027 cell Anatomy 0.000 claims 9
• 108091033319 polynucleotide Proteins 0.000 claims 7
• 102000040430 polynucleotide Human genes 0.000 claims 7
• 239000002157 polynucleotide Substances 0.000 claims 7
• 102000004169 proteins and genes Human genes 0.000 claims 7
• FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 6
• 239000012634 fragment Substances 0.000 claims 6
• 108020004465 16S ribosomal RNA Proteins 0.000 claims 5
• 150000001413 amino acids Chemical class 0.000 claims 4
• 241000894006 Bacteria Species 0.000 claims 3
• 239000013598 vector Substances 0.000 claims 3
• 241001465754 Metazoa Species 0.000 claims 2
• 125000003275 alpha amino acid group Chemical group 0.000 claims 2
• 230000001580 bacterial effect Effects 0.000 claims 2
• 230000003308 immunostimulating effect Effects 0.000 claims 2
• 239000003550 marker Substances 0.000 claims 2
• 238000000034 method Methods 0.000 claims 2
• 239000002773 nucleotide Substances 0.000 claims 2
• 125000003729 nucleotide group Chemical group 0.000 claims 2
• 230000008635 plant growth Effects 0.000 claims 2
• 230000008685 targeting Effects 0.000 claims 2
• 102000004190 Enzymes Human genes 0.000 claims 1
• 108090000790 Enzymes Proteins 0.000 claims 1
• 241000194105 Paenibacillus polymyxa Species 0.000 claims 1
• 241000058353 Paenibacillus terrae Species 0.000 claims 1
• 108091005804 Peptidases Proteins 0.000 claims 1
• 239000004365 Protease Substances 0.000 claims 1
• 241001646398 Pseudomonas chlororaphis Species 0.000 claims 1
• 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 claims 1
• 210000004507 artificial chromosome Anatomy 0.000 claims 1
• 210000003578 bacterial chromosome Anatomy 0.000 claims 1
• 238000003776 cleavage reaction Methods 0.000 claims 1
• 230000004927 fusion Effects 0.000 claims 1
• 239000013612 plasmid Substances 0.000 claims 1
• 238000000746 purification Methods 0.000 claims 1
• 108700022487 rRNA Genes Proteins 0.000 claims 1
• 230000007017 scission Effects 0.000 claims 1
• 230000004936 stimulating effect Effects 0.000 claims 1
• 230000001225 therapeutic effect Effects 0.000 claims 1
• 239000013603 viral vector Substances 0.000 claims 1
• 238000012800 visualization Methods 0.000 claims 1