JP2021503897A - 新生抗原のためのジャンクションエピトープ提示の低減 - Google Patents

新生抗原のためのジャンクションエピトープ提示の低減 Download PDF

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JP2021503897A
JP2021503897A JP2020528117A JP2020528117A JP2021503897A JP 2021503897 A JP2021503897 A JP 2021503897A JP 2020528117 A JP2020528117 A JP 2020528117A JP 2020528117 A JP2020528117 A JP 2020528117A JP 2021503897 A JP2021503897 A JP 2021503897A
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epitopes
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ブレンダン ブリク−スリバン
ブレンダン ブリク−スリバン
トーマス フランシス バウチャー
トーマス フランシス バウチャー
ローマン ヤレンスカイ
ローマン ヤレンスカイ
ジェニファー バスビー
ジェニファー バスビー
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グリットストーン オンコロジー インコーポレイテッド
グリットストーン オンコロジー インコーポレイテッド
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6878—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids in epitope analysis
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B30/00—Methods of screening libraries
    • C40B30/04—Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/20—Supervised data analysis

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  • General Health & Medical Sciences (AREA)
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  • Biotechnology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
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JP2020528117A 2017-11-22 2018-11-21 新生抗原のためのジャンクションエピトープ提示の低減 Pending JP2021503897A (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2023182917A JP7755628B2 (ja) 2017-11-22 2023-10-25 新生抗原のためのジャンクションエピトープ提示の低減
JP2025147998A JP2025175055A (ja) 2017-11-22 2025-09-08 新生抗原のためのジャンクションエピトープ提示の低減

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US201762590045P 2017-11-22 2017-11-22
US62/590,045 2017-11-22
PCT/US2018/062294 WO2019104203A1 (en) 2017-11-22 2018-11-21 Reducing junction epitope presentation for neoantigens

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JP2023182917A Division JP7755628B2 (ja) 2017-11-22 2023-10-25 新生抗原のためのジャンクションエピトープ提示の低減

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JP2021503897A true JP2021503897A (ja) 2021-02-15
JP2021503897A5 JP2021503897A5 (https=) 2022-01-04

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JP2023182917A Active JP7755628B2 (ja) 2017-11-22 2023-10-25 新生抗原のためのジャンクションエピトープ提示の低減
JP2025147998A Pending JP2025175055A (ja) 2017-11-22 2025-09-08 新生抗原のためのジャンクションエピトープ提示の低減

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JP2025147998A Pending JP2025175055A (ja) 2017-11-22 2025-09-08 新生抗原のためのジャンクションエピトープ提示の低減

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US (2) US11885815B2 (https=)
EP (1) EP3714275A4 (https=)
JP (3) JP2021503897A (https=)
KR (2) KR20260008173A (https=)
CN (1) CN111630602A (https=)
AU (2) AU2018373154B2 (https=)
CA (1) CA3083097A1 (https=)
IL (1) IL274799B2 (https=)
WO (1) WO2019104203A1 (https=)

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CA3083097A1 (en) 2017-11-22 2019-05-31 Gritstone Oncology, Inc. Reducing junction epitope presentation for neoantigens
EP3906045A1 (en) 2019-01-03 2021-11-10 Evaxion Biotech ApS Vaccines targeting neoepitopes
AU2020234003B2 (en) 2019-03-11 2026-02-12 Evaxion A/S Nucleic acid vaccination using neo-epitope encoding constructs
CN114761041A (zh) 2019-07-16 2022-07-15 吉利德科学公司 Hiv疫苗及其制备和使用方法
EP4028763A1 (en) 2019-09-13 2022-07-20 Evaxion Biotech A/S Method for identifying t-cell epitopes
US20230072079A1 (en) 2019-12-18 2023-03-09 Evaxion Biotech A/S Nucleic acid vaccination using neo-epitope encoding constructs
CN114929899B (zh) * 2020-01-07 2026-03-10 韩国科学技术院 一种新抗原的筛选方法、系统及其用途
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US20230355733A1 (en) 2020-07-14 2023-11-09 Evaxion Biotech A/S APC targeting units for immunotherapy
JP2024500804A (ja) * 2020-12-18 2024-01-10 イェダ リサーチ アンド ディベロップメント カンパニー リミテッド Ｃｈｄ２ハプロ不全の処置における使用のための組成物及びその同定方法
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CA3216276A1 (en) 2021-04-29 2022-11-03 Yardena Samuels T cell receptors directed against ras-derived recurrent neoantigens and methods of identifying same
KR102475794B1 (ko) * 2022-08-23 2022-12-08 주식회사 테라젠바이오 합성 긴 펩타이드의 면역원성 예측 장치, 면역원성 예측 방법 및 컴퓨터 프로그램

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CN111630602A (zh) 2020-09-04
IL274799B1 (en) 2025-01-01
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