JP2021501781A5 - - Google Patents

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Publication number
JP2021501781A5
JP2021501781A5 JP2020524777A JP2020524777A JP2021501781A5 JP 2021501781 A5 JP2021501781 A5 JP 2021501781A5 JP 2020524777 A JP2020524777 A JP 2020524777A JP 2020524777 A JP2020524777 A JP 2020524777A JP 2021501781 A5 JP2021501781 A5 JP 2021501781A5
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JP
Japan
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alkyl
formula
compound
halo
group
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Pending
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JP2020524777A
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English (en)
Japanese (ja)
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JP2021501781A (ja
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Priority claimed from PCT/US2018/058963 external-priority patent/WO2019090081A1/en
Publication of JP2021501781A publication Critical patent/JP2021501781A/ja
Publication of JP2021501781A5 publication Critical patent/JP2021501781A5/ja
Pending legal-status Critical Current

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JP2020524777A 2017-11-02 2018-11-02 統合的ストレス経路の調節剤 Pending JP2021501781A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762580776P 2017-11-02 2017-11-02
US62/580,776 2017-11-02
US201862643071P 2018-03-14 2018-03-14
US62/643,071 2018-03-14
PCT/US2018/058963 WO2019090081A1 (en) 2017-11-02 2018-11-02 Modulators of the integrated stress pathway

Publications (2)

Publication Number Publication Date
JP2021501781A JP2021501781A (ja) 2021-01-21
JP2021501781A5 true JP2021501781A5 (enExample) 2021-12-09

Family

ID=64650479

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020524777A Pending JP2021501781A (ja) 2017-11-02 2018-11-02 統合的ストレス経路の調節剤

Country Status (12)

Country Link
US (1) US20200347033A1 (enExample)
EP (1) EP3704091B1 (enExample)
JP (1) JP2021501781A (enExample)
KR (1) KR20200096523A (enExample)
CN (1) CN112218851A (enExample)
AU (2) AU2018360850A1 (enExample)
BR (1) BR112020008833A2 (enExample)
CA (1) CA3080959A1 (enExample)
IL (1) IL274406B2 (enExample)
MX (1) MX2020004534A (enExample)
SG (1) SG11202004009TA (enExample)
WO (1) WO2019090081A1 (enExample)

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Publication number Priority date Publication date Assignee Title
CN110730777A (zh) * 2017-06-07 2020-01-24 葛兰素史密斯克莱知识产权发展有限公司 作为atf4通路抑制剂的化学化合物
IL301709B2 (en) 2017-08-09 2025-07-01 Denali Therapeutics Inc Compounds, compositions and methods
TW201920129A (zh) 2017-09-01 2019-06-01 美商戴納立製藥公司 化合物、組合物及方法
JP2021501785A (ja) 2017-11-02 2021-01-21 カリコ ライフ サイエンシーズ エルエルシー 統合的ストレス経路の調節剤
JP2021508336A (ja) 2017-12-13 2021-03-04 プラクシス バイオテック エルエルシー 統合的ストレス応答経路の阻害剤
US11166942B2 (en) 2018-06-05 2021-11-09 Praxis Biotech LLC Inhibitors of integrated stress response pathway
TW202545902A (zh) 2018-10-11 2025-12-01 美商嘉來克生命科學有限責任公司 整合應激路徑之前藥調節劑
EP3924341A4 (en) 2019-02-13 2022-11-02 Denali Therapeutics Inc. Compounds, compositions and methods
CR20210426A (es) 2019-02-13 2021-09-30 Denali Therapeutics Inc Compuestos, composiciones y métodos
MX2021012904A (es) 2019-04-23 2022-01-18 Evotec Int Gmbh Moduladores de la via de respuesta al estres integrada.
WO2020216766A1 (en) * 2019-04-23 2020-10-29 Evotec International Gmbh Modulators of the integrated stress response pathway
JP2022536663A (ja) 2019-06-12 2022-08-18 プラクシス バイオテック エルエルシー 統合的ストレス応答経路のモジュレーター
CA3162526A1 (en) 2020-01-28 2021-08-05 Christopher John Brown Modulators of the integrated stress response pathway
KR20220151635A (ko) * 2020-03-11 2022-11-15 에보텍 인터내셔널 게엠베하 통합 스트레스 반응 경로의 조절제
ES2997335T3 (en) 2020-10-22 2025-02-17 Evotec Int Gmbh Modulators of the integrated stress response pathway
MX2023004677A (es) 2020-10-22 2023-05-24 Evotec Int Gmbh Moduladores de la via de respuesta integrada al estres.
CA3195290A1 (en) 2020-10-22 2022-04-28 Holly Victoria Atton Modulators of the integrated stress response pathway
TW202241857A (zh) 2020-12-18 2022-11-01 美商戴納立製藥公司 化合物之固體形式
CN116768877B (zh) * 2022-05-30 2026-03-31 中国药科大学 Isr抑制剂及其制备方法和应用

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