JP2021501790A5 - - Google Patents

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JP2021501790A5
JP2021501790A5 JP2020524870A JP2020524870A JP2021501790A5 JP 2021501790 A5 JP2021501790 A5 JP 2021501790A5 JP 2020524870 A JP2020524870 A JP 2020524870A JP 2020524870 A JP2020524870 A JP 2020524870A JP 2021501790 A5 JP2021501790 A5 JP 2021501790A5
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JP
Japan
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alkyl
disease
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diseases
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JP2020524870A
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Japanese (ja)
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JP7335241B2 (ja
JP2021501790A (ja
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Priority claimed from PCT/US2018/058955 external-priority patent/WO2019090074A1/en
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Publication of JP2021501790A5 publication Critical patent/JP2021501790A5/ja
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JP2020524870A 2017-11-02 2018-11-02 統合的ストレス経路の調節剤 Active JP7335241B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762580734P 2017-11-02 2017-11-02
US62/580,734 2017-11-02
US201862643061P 2018-03-14 2018-03-14
US62/643,061 2018-03-14
PCT/US2018/058955 WO2019090074A1 (en) 2017-11-02 2018-11-02 Modulators of the integrated stress pathway

Publications (3)

Publication Number Publication Date
JP2021501790A JP2021501790A (ja) 2021-01-21
JP2021501790A5 true JP2021501790A5 (enExample) 2021-12-09
JP7335241B2 JP7335241B2 (ja) 2023-08-29

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ID=64564979

Family Applications (1)

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JP2020524870A Active JP7335241B2 (ja) 2017-11-02 2018-11-02 統合的ストレス経路の調節剤

Country Status (12)

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US (2) US20210393599A1 (enExample)
EP (1) EP3704089B1 (enExample)
JP (1) JP7335241B2 (enExample)
KR (1) KR20200092332A (enExample)
CN (1) CN112204006B (enExample)
AU (1) AU2018360855B2 (enExample)
BR (1) BR112020008817B8 (enExample)
CA (1) CA3080804A1 (enExample)
IL (1) IL274367B2 (enExample)
MX (1) MX2020004538A (enExample)
SG (1) SG11202004074TA (enExample)
WO (1) WO2019090074A1 (enExample)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111094233B (zh) 2017-08-09 2024-03-15 戴纳立制药公司 化合物、组合物及方法
PT3676297T (pt) 2017-09-01 2023-08-29 Denali Therapeutics Inc Compostos, composições e métodos
JP2021501785A (ja) 2017-11-02 2021-01-21 カリコ ライフ サイエンシーズ エルエルシー 統合的ストレス経路の調節剤
RU2020122711A (ru) 2017-12-13 2022-01-17 ПРАКСИС БАЙОТЕК ЭлЭлСи Ингибиторы пути интегрированной реакции на стресс
WO2019204180A1 (en) 2018-04-19 2019-10-24 Merck Sharp & Dohme Corp. Novel [1.1.1] bicyclo compounds as indoleamine 2,3-dioxygenase inhibitors
SG11202011014VA (en) 2018-06-05 2020-12-30 Praxis Biotech LLC Inhibitors of integrated stress response pathway
TWI832295B (zh) 2018-10-11 2024-02-11 美商嘉來克生命科學有限責任公司 整合應激路徑之前藥調節劑
MA54959A (fr) 2019-02-13 2021-12-22 Denali Therapeutics Inc Composés, compositions et procédés
CA3129609A1 (en) 2019-02-13 2020-08-20 Denali Therapeutics Inc. Eukaryotic initiation factor 2b modulators
AU2020261234A1 (en) 2019-04-23 2021-11-11 Evotec International Gmbh Modulators of the integrated stress response pathway
EA202192900A1 (ru) 2019-04-23 2022-03-18 Эвотек Интернешнл Гмбх Модуляторы пути интегрированной реакции на стресс
CA3142748A1 (en) 2019-06-12 2020-12-17 Praxis Biotech LLC Modulators of integrated stress response pathway
KR20220133252A (ko) 2020-01-28 2022-10-04 에보텍 인터내셔널 게엠베하 통합 스트레스 반응 경로의 조절자
JP2023517944A (ja) 2020-03-11 2023-04-27 エヴォテック・インターナショナル・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 統合的ストレス応答経路の調節因子
US20230391763A1 (en) 2020-10-22 2023-12-07 Evotec International Gmbh Modulators of the integrated stress response pathway
AU2021366303A1 (en) 2020-10-22 2023-06-22 Evotec International Gmbh Modulators of the integrated stress response pathway
CA3195290A1 (en) * 2020-10-22 2022-04-28 Holly Victoria Atton Modulators of the integrated stress response pathway
CN116693529A (zh) * 2023-06-09 2023-09-05 河南师范大学 一种2-氮杂环[2.2.2]辛烷类化合物的合成方法
WO2024263972A2 (en) * 2023-06-21 2024-12-26 Burzynski Stanislaw R Compositions comprising antineoplastons and methods of treating uncommon cancers
TW202529763A (zh) * 2024-01-17 2025-08-01 大陸商北京泰德製藥股份有限公司 血管緊張素ii受體拮抗劑及其用於治療周圍神經病理性疼痛的用途

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Publication number Priority date Publication date Assignee Title
US4911920A (en) 1986-07-30 1990-03-27 Alcon Laboratories, Inc. Sustained release, comfort formulation for glaucoma therapy
FR2588189B1 (fr) 1985-10-03 1988-12-02 Merck Sharp & Dohme Composition pharmaceutique de type a transition de phase liquide-gel
EP0495421B1 (en) 1991-01-15 1996-08-21 Alcon Laboratories, Inc. Use of carrageenans in topical ophthalmic compositions
US5212162A (en) 1991-03-27 1993-05-18 Alcon Laboratories, Inc. Use of combinations gelling polysaccharides and finely divided drug carrier substrates in topical ophthalmic compositions
JP2013513664A (ja) * 2009-12-14 2013-04-22 インスパイアー ファーマシューティカルズ,インコーポレイティド 架橋二環式rhoキナーゼ阻害化合物、組成および使用
AR084457A1 (es) 2010-12-22 2013-05-15 Lundbeck & Co As H Derivados de biciclo[3,2,1]octilamida
WO2013003383A1 (en) * 2011-06-27 2013-01-03 Kyorin Pharmaceutical Co., Ltd. Bridged bicyclic compounds for the treatment of bacterial infections
AU2014233520B2 (en) * 2013-03-15 2019-02-21 The Regents Of The University Of California Modulators of the eIF2alpha pathway
CU20170139A7 (es) 2015-05-05 2018-03-13 Bayer Pharma AG Derivados de ciclohexano sustituido con amido
EP3340982B1 (en) 2015-08-26 2021-12-15 Achillion Pharmaceuticals, Inc. Compounds for treatment of immune and inflammatory disorders
TW201808903A (zh) 2016-05-05 2018-03-16 嘉來克生命科學有限責任公司 整合應激途徑之調節劑

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