JP2021501780A5 - - Google Patents

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Publication number
JP2021501780A5
JP2021501780A5 JP2020524776A JP2020524776A JP2021501780A5 JP 2021501780 A5 JP2021501780 A5 JP 2021501780A5 JP 2020524776 A JP2020524776 A JP 2020524776A JP 2020524776 A JP2020524776 A JP 2020524776A JP 2021501780 A5 JP2021501780 A5 JP 2021501780A5
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JP
Japan
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alkyl
halo
group
disease
cyano
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JP2020524776A
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English (en)
Japanese (ja)
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JP2021501780A (ja
JP7307057B2 (ja
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Priority claimed from PCT/US2018/058974 external-priority patent/WO2019090090A1/en
Publication of JP2021501780A publication Critical patent/JP2021501780A/ja
Publication of JP2021501780A5 publication Critical patent/JP2021501780A5/ja
Application granted granted Critical
Publication of JP7307057B2 publication Critical patent/JP7307057B2/ja
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JP2020524776A 2017-11-02 2018-11-02 統合的ストレス経路の調節剤 Active JP7307057B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762580820P 2017-11-02 2017-11-02
US62/580,820 2017-11-02
US201862643079P 2018-03-14 2018-03-14
US62/643,079 2018-03-14
PCT/US2018/058974 WO2019090090A1 (en) 2017-11-02 2018-11-02 Modulators of the integrated stress pathway

Publications (3)

Publication Number Publication Date
JP2021501780A JP2021501780A (ja) 2021-01-21
JP2021501780A5 true JP2021501780A5 (enExample) 2021-12-09
JP7307057B2 JP7307057B2 (ja) 2023-07-11

Family

ID=64572461

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020524776A Active JP7307057B2 (ja) 2017-11-02 2018-11-02 統合的ストレス経路の調節剤

Country Status (9)

Country Link
US (1) US20230192712A1 (enExample)
EP (1) EP3704125B1 (enExample)
JP (1) JP7307057B2 (enExample)
CN (1) CN112218869A (enExample)
AU (1) AU2018360854B2 (enExample)
BR (1) BR112020008836A2 (enExample)
CA (1) CA3080948A1 (enExample)
MX (1) MX2020004556A (enExample)
WO (1) WO2019090090A1 (enExample)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL301709B2 (en) 2017-08-09 2025-07-01 Denali Therapeutics Inc Compounds, compositions and methods
TW201920129A (zh) 2017-09-01 2019-06-01 美商戴納立製藥公司 化合物、組合物及方法
JP2021501785A (ja) 2017-11-02 2021-01-21 カリコ ライフ サイエンシーズ エルエルシー 統合的ストレス経路の調節剤
SG11202004009TA (en) * 2017-11-02 2020-05-28 Calico Life Sciences Llc Modulators of the integrated stress pathway
JP2021508336A (ja) 2017-12-13 2021-03-04 プラクシス バイオテック エルエルシー 統合的ストレス応答経路の阻害剤
US11166942B2 (en) 2018-06-05 2021-11-09 Praxis Biotech LLC Inhibitors of integrated stress response pathway
TW202545902A (zh) 2018-10-11 2025-12-01 美商嘉來克生命科學有限責任公司 整合應激路徑之前藥調節劑
CR20210426A (es) 2019-02-13 2021-09-30 Denali Therapeutics Inc Compuestos, composiciones y métodos
EP3924341A4 (en) 2019-02-13 2022-11-02 Denali Therapeutics Inc. Compounds, compositions and methods
MX2021012904A (es) 2019-04-23 2022-01-18 Evotec Int Gmbh Moduladores de la via de respuesta al estres integrada.
WO2020216766A1 (en) 2019-04-23 2020-10-29 Evotec International Gmbh Modulators of the integrated stress response pathway
WO2020252025A1 (en) * 2019-06-11 2020-12-17 Yale University Compositions for pathogenesis-directed therapy and treatments of skin diseases and disorders
JP2022536663A (ja) 2019-06-12 2022-08-18 プラクシス バイオテック エルエルシー 統合的ストレス応答経路のモジュレーター
IL291665B2 (en) 2019-09-27 2025-07-01 Univ Texas Inhibitors of receptor interacting protein kinase i for the treatment of disease
CA3162526A1 (en) 2020-01-28 2021-08-05 Christopher John Brown Modulators of the integrated stress response pathway
KR20220151635A (ko) 2020-03-11 2022-11-15 에보텍 인터내셔널 게엠베하 통합 스트레스 반응 경로의 조절제
MX2023004677A (es) 2020-10-22 2023-05-24 Evotec Int Gmbh Moduladores de la via de respuesta integrada al estres.
ES2997335T3 (en) 2020-10-22 2025-02-17 Evotec Int Gmbh Modulators of the integrated stress response pathway
CA3195290A1 (en) 2020-10-22 2022-04-28 Holly Victoria Atton Modulators of the integrated stress response pathway
TW202241857A (zh) 2020-12-18 2022-11-01 美商戴納立製藥公司 化合物之固體形式

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4911920A (en) 1986-07-30 1990-03-27 Alcon Laboratories, Inc. Sustained release, comfort formulation for glaucoma therapy
FR2588189B1 (fr) 1985-10-03 1988-12-02 Merck Sharp & Dohme Composition pharmaceutique de type a transition de phase liquide-gel
DK0495421T3 (da) 1991-01-15 1996-12-09 Alcon Lab Inc Anvendelse af carragenaner i topiske ophthalmiske sammensætninger
US5212162A (en) 1991-03-27 1993-05-18 Alcon Laboratories, Inc. Use of combinations gelling polysaccharides and finely divided drug carrier substrates in topical ophthalmic compositions
US5686454A (en) * 1993-07-16 1997-11-11 Merck & Co., Inc. Camphorcarbonyl
AU2005212073B2 (en) * 2004-02-18 2010-07-08 Kyorin Pharmaceutical Co., Ltd. Bicyclic amide derivatives
WO2014144952A2 (en) * 2013-03-15 2014-09-18 Peter Walter Modulators of the eif2alpha pathway

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