JP2021501780A5 - - Google Patents

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Publication number
JP2021501780A5
JP2021501780A5 JP2020524776A JP2020524776A JP2021501780A5 JP 2021501780 A5 JP2021501780 A5 JP 2021501780A5 JP 2020524776 A JP2020524776 A JP 2020524776A JP 2020524776 A JP2020524776 A JP 2020524776A JP 2021501780 A5 JP2021501780 A5 JP 2021501780A5
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JP
Japan
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alkyl
halo
group
disease
cyano
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JP2020524776A
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English (en)
Japanese (ja)
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JP2021501780A (ja
JP7307057B2 (ja
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Priority claimed from PCT/US2018/058974 external-priority patent/WO2019090090A1/en
Publication of JP2021501780A publication Critical patent/JP2021501780A/ja
Publication of JP2021501780A5 publication Critical patent/JP2021501780A5/ja
Application granted granted Critical
Publication of JP7307057B2 publication Critical patent/JP7307057B2/ja
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JP2020524776A 2017-11-02 2018-11-02 統合的ストレス経路の調節剤 Active JP7307057B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762580820P 2017-11-02 2017-11-02
US62/580,820 2017-11-02
US201862643079P 2018-03-14 2018-03-14
US62/643,079 2018-03-14
PCT/US2018/058974 WO2019090090A1 (en) 2017-11-02 2018-11-02 Modulators of the integrated stress pathway

Publications (3)

Publication Number Publication Date
JP2021501780A JP2021501780A (ja) 2021-01-21
JP2021501780A5 true JP2021501780A5 (enExample) 2021-12-09
JP7307057B2 JP7307057B2 (ja) 2023-07-11

Family

ID=64572461

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020524776A Active JP7307057B2 (ja) 2017-11-02 2018-11-02 統合的ストレス経路の調節剤

Country Status (9)

Country Link
US (1) US20230192712A1 (enExample)
EP (1) EP3704125A1 (enExample)
JP (1) JP7307057B2 (enExample)
CN (1) CN112218869A (enExample)
AU (1) AU2018360854B2 (enExample)
BR (1) BR112020008836A2 (enExample)
CA (1) CA3080948A1 (enExample)
MX (1) MX2020004556A (enExample)
WO (1) WO2019090090A1 (enExample)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111094233B (zh) 2017-08-09 2024-03-15 戴纳立制药公司 化合物、组合物及方法
PT3676297T (pt) 2017-09-01 2023-08-29 Denali Therapeutics Inc Compostos, composições e métodos
JP2021501785A (ja) 2017-11-02 2021-01-21 カリコ ライフ サイエンシーズ エルエルシー 統合的ストレス経路の調節剤
US20200347033A1 (en) * 2017-11-02 2020-11-05 Calico Life Sciences Llc Modulators of the integrated stress pathway
RU2020122711A (ru) 2017-12-13 2022-01-17 ПРАКСИС БАЙОТЕК ЭлЭлСи Ингибиторы пути интегрированной реакции на стресс
SG11202011014VA (en) 2018-06-05 2020-12-30 Praxis Biotech LLC Inhibitors of integrated stress response pathway
TWI832295B (zh) 2018-10-11 2024-02-11 美商嘉來克生命科學有限責任公司 整合應激路徑之前藥調節劑
MA54959A (fr) 2019-02-13 2021-12-22 Denali Therapeutics Inc Composés, compositions et procédés
CA3129609A1 (en) 2019-02-13 2020-08-20 Denali Therapeutics Inc. Eukaryotic initiation factor 2b modulators
AU2020261234A1 (en) 2019-04-23 2021-11-11 Evotec International Gmbh Modulators of the integrated stress response pathway
EA202192900A1 (ru) 2019-04-23 2022-03-18 Эвотек Интернешнл Гмбх Модуляторы пути интегрированной реакции на стресс
US20220168270A1 (en) * 2019-06-11 2022-06-02 Yale University Compositions for pathogenesis-directed therapy and treatments of skin diseases and disorders
CA3142748A1 (en) 2019-06-12 2020-12-17 Praxis Biotech LLC Modulators of integrated stress response pathway
IL291665B2 (en) * 2019-09-27 2025-07-01 Univ Texas Inhibitors of receptor interacting protein kinase i for the treatment of disease
KR20220133252A (ko) 2020-01-28 2022-10-04 에보텍 인터내셔널 게엠베하 통합 스트레스 반응 경로의 조절자
JP2023517944A (ja) 2020-03-11 2023-04-27 エヴォテック・インターナショナル・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 統合的ストレス応答経路の調節因子
AU2021366303A1 (en) 2020-10-22 2023-06-22 Evotec International Gmbh Modulators of the integrated stress response pathway
US20230391763A1 (en) 2020-10-22 2023-12-07 Evotec International Gmbh Modulators of the integrated stress response pathway
CA3195290A1 (en) * 2020-10-22 2022-04-28 Holly Victoria Atton Modulators of the integrated stress response pathway

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4911920A (en) 1986-07-30 1990-03-27 Alcon Laboratories, Inc. Sustained release, comfort formulation for glaucoma therapy
FR2588189B1 (fr) 1985-10-03 1988-12-02 Merck Sharp & Dohme Composition pharmaceutique de type a transition de phase liquide-gel
EP0495421B1 (en) 1991-01-15 1996-08-21 Alcon Laboratories, Inc. Use of carrageenans in topical ophthalmic compositions
US5212162A (en) 1991-03-27 1993-05-18 Alcon Laboratories, Inc. Use of combinations gelling polysaccharides and finely divided drug carrier substrates in topical ophthalmic compositions
CA2166974A1 (en) * 1993-07-16 1995-01-26 Mark G. Bock Substituted amide derivatives of piperizinylcamphor sulfonyl and carbonyl oxytocin antagonists
AU2005212073B2 (en) * 2004-02-18 2010-07-08 Kyorin Pharmaceutical Co., Ltd. Bicyclic amide derivatives
AU2014233520B2 (en) * 2013-03-15 2019-02-21 The Regents Of The University Of California Modulators of the eIF2alpha pathway

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