JP2021098733A5 - - Google Patents

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Publication number
JP2021098733A5
JP2021098733A5 JP2021037490A JP2021037490A JP2021098733A5 JP 2021098733 A5 JP2021098733 A5 JP 2021098733A5 JP 2021037490 A JP2021037490 A JP 2021037490A JP 2021037490 A JP2021037490 A JP 2021037490A JP 2021098733 A5 JP2021098733 A5 JP 2021098733A5
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JP
Japan
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seq
amino acid
acid sequence
heavy chain
light chain
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Pending
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JP2021037490A
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English (en)
Japanese (ja)
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JP2021098733A (ja
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Priority claimed from JP2020513796A external-priority patent/JP7431392B2/ja
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Publication of JP2021098733A publication Critical patent/JP2021098733A/ja
Publication of JP2021098733A5 publication Critical patent/JP2021098733A5/ja
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JP2021037490A 2017-09-07 2021-03-09 Nkg2d、cd16および腫瘍関連抗原に結合するタンパク質 Pending JP2021098733A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762555110P 2017-09-07 2017-09-07
US62/555,110 2017-09-07
US201762566824P 2017-10-02 2017-10-02
US62/566,824 2017-10-02
JP2020513796A JP7431392B2 (ja) 2017-09-07 2018-09-07 NKG2D、CD16およびNectin4に結合するタンパク質

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2020513796A Division JP7431392B2 (ja) 2017-09-07 2018-09-07 NKG2D、CD16およびNectin4に結合するタンパク質

Publications (2)

Publication Number Publication Date
JP2021098733A JP2021098733A (ja) 2021-07-01
JP2021098733A5 true JP2021098733A5 (enExample) 2021-10-14

Family

ID=65634405

Family Applications (4)

Application Number Title Priority Date Filing Date
JP2020513796A Active JP7431392B2 (ja) 2017-09-07 2018-09-07 NKG2D、CD16およびNectin4に結合するタンパク質
JP2021037490A Pending JP2021098733A (ja) 2017-09-07 2021-03-09 Nkg2d、cd16および腫瘍関連抗原に結合するタンパク質
JP2023132099A Pending JP2023166409A (ja) 2017-09-07 2023-08-14 Nkg2d、cd16および腫瘍関連抗原に結合するタンパク質
JP2025026082A Pending JP2025093943A (ja) 2017-09-07 2025-02-20 Nkg2d、cd16および腫瘍関連抗原に結合するタンパク質

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2020513796A Active JP7431392B2 (ja) 2017-09-07 2018-09-07 NKG2D、CD16およびNectin4に結合するタンパク質

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2023132099A Pending JP2023166409A (ja) 2017-09-07 2023-08-14 Nkg2d、cd16および腫瘍関連抗原に結合するタンパク質
JP2025026082A Pending JP2025093943A (ja) 2017-09-07 2025-02-20 Nkg2d、cd16および腫瘍関連抗原に結合するタンパク質

Country Status (13)

Country Link
US (3) US20200277383A1 (enExample)
EP (2) EP3925976A1 (enExample)
JP (4) JP7431392B2 (enExample)
KR (3) KR20240167101A (enExample)
CN (3) CN111315782A (enExample)
AU (3) AU2018329937B2 (enExample)
BR (1) BR112020004489A2 (enExample)
CA (2) CA3112984A1 (enExample)
IL (2) IL273067A (enExample)
MX (2) MX420258B (enExample)
RU (1) RU2021110369A (enExample)
SG (2) SG11202001930QA (enExample)
WO (1) WO2019051308A1 (enExample)

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CA3053010A1 (en) 2017-02-08 2018-08-16 Dragonfly Therapeutics, Inc. Multi-specific binding proteins for activation of natural killer cells and therapeutic uses thereof to treat cancer
CA3054079A1 (en) 2017-02-20 2018-08-23 Dragonfly Therapeutics, Inc. Proteins binding her2, nkg2d and cd16
DK3749346T3 (da) 2018-02-08 2024-09-09 Dragonfly Therapeutics Inc Antistof variable domænekombinationer rettet mod nkg2d-receptoren
JP2021512914A (ja) 2018-02-08 2021-05-20 ドラゴンフライ セラピューティクス, インコーポレイテッド ナチュラルキラー細胞を活性化する多特異的結合タンパク質を伴うがんの併用療法
SG11202007945UA (en) 2018-02-20 2020-09-29 Dragonfly Therapeutics Inc Multi-specific binding proteins that bind cd33, nkg2d, and cd16, and methods of use
EA202091977A1 (ru) * 2018-05-28 2021-02-09 Драгонфлай Терапьютикс, Инк. Мультиспецифические связывающие белки, которые связывают cd33, nkg2d и cd16, и способы применения
WO2020033630A1 (en) 2018-08-08 2020-02-13 Dragonfly Therapeutics, Inc. Multi-specific binding proteins that bind bcma, nkg2d and cd16, and methods of use
KR20250112921A (ko) 2018-08-08 2025-07-24 드래곤플라이 쎄라퓨틱스, 인크. Nkg2d, cd16 및 종양 관련 항원에 결합하는 단백질
EA202091888A1 (ru) 2018-08-08 2020-10-23 Драгонфлай Терапьютикс, Инк. Вариабельные домены антител, нацеленные на рецептор nkg2d
EP3870598A1 (en) 2018-10-23 2021-09-01 Dragonfly Therapeutics, Inc. Heterodimeric fc-fused proteins
CN113677364B (zh) 2018-12-03 2024-07-05 艾更斯司股份有限公司 包含抗191p4d12抗体药物偶联物的药物组合物及其使用方法
JP2022553818A (ja) * 2019-10-30 2022-12-26 ザ テキサス エー アンド エム ユニバーシティ システム 二重標的キメラ抗原レセプターt細胞療法のためのプロテアーゼスイッチ
MX2022013112A (es) * 2020-04-22 2023-01-16 Dragonfly Therapeutics Inc Fórmulacion, regimen de dosificación y proceso de manufactura de proteínas heterodiméricas fusionadas con fc.
BR112022021884A2 (pt) 2020-05-06 2022-12-20 Dragonfly Therapeutics Inc Proteínas que se ligam a nkg2d, cd16 e clec12a
AU2021344976A1 (en) * 2020-09-17 2023-04-27 Agensys, Inc. Methods for treating cancers with antibody drug conjugates (adc) that bind to 191p4d12 proteins
CN117222663A (zh) 2021-03-03 2023-12-12 蜻蜓疗法股份有限公司 使用结合nkg2d、cd16和肿瘤相关抗原的多特异性结合蛋白治疗癌症的方法
CN113563474B (zh) * 2021-06-11 2023-05-02 广州医科大学附属第三医院(广州重症孕产妇救治中心、广州柔济医院) EpCAM-CD16-NKG2D三特异性抗体及其应用
EP4388103A1 (en) * 2021-08-20 2024-06-26 Tallac Therapeutics, Inc. Nectin-4 antibodies and conjugates
AU2022358500A1 (en) * 2021-09-29 2024-04-04 Dragonfly Therapeutics, Inc. Proteins binding nkg2d, cd16 and baff-r
KR20230060546A (ko) * 2021-10-22 2023-05-04 상트네어바이오사이언스 주식회사 두개의 Fc 도메인을 포함하는 항원 결합 단백질 및 이의 용도
AU2023316566A1 (en) * 2022-07-25 2025-01-30 Agensys, Inc. Methods for treating patients with locally advanced or metastatic urothelial cancer with antibody drug conjugates (adc) that bind 191p4d12 proteins in combination with pembrolizumab

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WO2015095412A1 (en) 2013-12-19 2015-06-25 Zhong Wang Bispecific antibody with two single-domain antigen-binding fragments
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WO2017042210A1 (en) 2015-09-09 2017-03-16 INSERM (Institut National de la Santé et de la Recherche Médicale) Antibodies having specificity to nectin-4 and uses thereof
CA3053010A1 (en) * 2017-02-08 2018-08-16 Dragonfly Therapeutics, Inc. Multi-specific binding proteins for activation of natural killer cells and therapeutic uses thereof to treat cancer
DK3749346T3 (da) * 2018-02-08 2024-09-09 Dragonfly Therapeutics Inc Antistof variable domænekombinationer rettet mod nkg2d-receptoren
CN117222663A (zh) * 2021-03-03 2023-12-12 蜻蜓疗法股份有限公司 使用结合nkg2d、cd16和肿瘤相关抗原的多特异性结合蛋白治疗癌症的方法
US20230416402A1 (en) * 2022-03-03 2023-12-28 Dragonfly Therapeutics, Inc. Methods of treating cancer using multi-specific binding proteins that bind nkg2d, cd16, and her2

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