JP2020507577A5 - - Google Patents
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- Publication number
- JP2020507577A5 JP2020507577A5 JP2019543270A JP2019543270A JP2020507577A5 JP 2020507577 A5 JP2020507577 A5 JP 2020507577A5 JP 2019543270 A JP2019543270 A JP 2019543270A JP 2019543270 A JP2019543270 A JP 2019543270A JP 2020507577 A5 JP2020507577 A5 JP 2020507577A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- seq
- acid sequence
- variable domain
- chain variable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022074378A JP2022105121A (ja) | 2017-02-10 | 2022-04-28 | Ｐｓｍａ、ｎｋｇ２ｄおよびｃｄ１６に結合するタンパク質 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762457785P | 2017-02-10 | 2017-02-10 | |
| US62/457,785 | 2017-02-10 | ||
| PCT/US2018/017718 WO2018148610A1 (en) | 2017-02-10 | 2018-02-10 | Proteins binding psma, nkg2d and cd16 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022074378A Division JP2022105121A (ja) | 2017-02-10 | 2022-04-28 | Ｐｓｍａ、ｎｋｇ２ｄおよびｃｄ１６に結合するタンパク質 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020507577A JP2020507577A (ja) | 2020-03-12 |
| JP2020507577A5 true JP2020507577A5 (enExample) | 2021-03-25 |
Family
ID=63107819
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019543270A Withdrawn JP2020507577A (ja) | 2017-02-10 | 2018-02-10 | Ｐｓｍａ、ｎｋｇ２ｄおよびｃｄ１６に結合するタンパク質 |
| JP2022074378A Withdrawn JP2022105121A (ja) | 2017-02-10 | 2022-04-28 | Ｐｓｍａ、ｎｋｇ２ｄおよびｃｄ１６に結合するタンパク質 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022074378A Withdrawn JP2022105121A (ja) | 2017-02-10 | 2022-04-28 | Ｐｓｍａ、ｎｋｇ２ｄおよびｃｄ１６に結合するタンパク質 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20200024353A1 (enExample) |
| EP (1) | EP3579878A4 (enExample) |
| JP (2) | JP2020507577A (enExample) |
| KR (1) | KR20190120770A (enExample) |
| CN (1) | CN110913902A (enExample) |
| AU (1) | AU2018217834A1 (enExample) |
| BR (1) | BR112019016553A2 (enExample) |
| CA (1) | CA3053275A1 (enExample) |
| IL (1) | IL268574A (enExample) |
| MX (1) | MX2019009541A (enExample) |
| RU (1) | RU2019128204A (enExample) |
| SG (1) | SG11201907271PA (enExample) |
| WO (1) | WO2018148610A1 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110944651A (zh) | 2017-02-08 | 2020-03-31 | 蜻蜓疗法股份有限公司 | 用于自然杀伤细胞激活的多特异性结合蛋白及其治疗癌症的治疗性用途 |
| EP4273258A3 (en) | 2017-02-20 | 2024-01-17 | Dragonfly Therapeutics, Inc. | Proteins binding her2, nkg2d and cd16 |
| MX2020008333A (es) | 2018-02-08 | 2020-09-21 | Dragonfly Therapeutics Inc | Terapia de combinacion del cancer que incluye proteinas de union multiespecificas que activan a las celulas asesinas naturales. |
| CA3090244A1 (en) | 2018-02-08 | 2019-08-15 | Dragonfly Therapeutics, Inc. | Antibody variable domains targeting the nkg2d receptor |
| CN112119093A (zh) | 2018-02-20 | 2020-12-22 | 蜻蜓治疗公司 | 结合cd33、nkg2d和cd16的多特异性结合蛋白和使用方法 |
| CA3108427A1 (en) | 2018-08-08 | 2020-02-13 | Dragonfly Therapeutics, Inc. | Multi-specific binding proteins that bind bcma, nkg2d and cd16, and methods of use |
| CN113164570B (zh) | 2018-08-08 | 2024-05-14 | 蜻蜓疗法股份有限公司 | 结合nkg2d、cd16和肿瘤相关抗原的蛋白质 |
| EA202091888A1 (ru) | 2018-08-08 | 2020-10-23 | Драгонфлай Терапьютикс, Инк. | Вариабельные домены антител, нацеленные на рецептор nkg2d |
| AU2021268340A1 (en) | 2020-05-06 | 2022-12-08 | Dragonfly Therapeutics, Inc. | Proteins binding NKG2D, CD16 and CLEC12A |
| EP4301774A4 (en) | 2021-03-03 | 2025-08-13 | Dragonfly Therapeutics Inc | METHODS OF TREATING CANCER USING MULTI-SPECIFIC BINDING PROTEINS THAT BIND TO NKG2D, CD16, AND A TUMOR-ASSOCIATED ANTIGEN |
| WO2023011431A1 (zh) * | 2021-08-03 | 2023-02-09 | 江苏先声药业有限公司 | 一种cd16抗体及其应用 |
| CN117915950A (zh) * | 2021-08-06 | 2024-04-19 | 甘李药业股份有限公司 | 一种多特异性抗体及其用途 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1266014A2 (en) * | 2000-03-24 | 2002-12-18 | Peter Kufer | Multifunctional polypeptides comprising a binding site to an epitope of the nkg2d receptor complex |
| US6455712B1 (en) * | 2000-12-13 | 2002-09-24 | Shell Oil Company | Preparation of oxirane compounds |
| WO2007002905A1 (en) * | 2005-06-29 | 2007-01-04 | University Of Miami | Antibody-immune cell ligand fusion protein for cancer therapy |
| CA2628253A1 (en) * | 2005-11-03 | 2007-08-30 | Genentech, Inc. | Therapeutic anti-her2 antibody fusion polypeptides |
| CN105837690A (zh) * | 2006-06-12 | 2016-08-10 | 新兴产品开发西雅图有限公司 | 具有效应功能的单链多价结合蛋白 |
| WO2009077483A1 (en) * | 2007-12-14 | 2009-06-25 | Novo Nordisk A/S | Antibodies against human nkg2d and uses thereof |
| US8629247B2 (en) * | 2009-04-14 | 2014-01-14 | Proscan Rx Pharma Inc. | Antibodies against prostate specific membrane antigen |
| TW201109438A (en) * | 2009-07-29 | 2011-03-16 | Abbott Lab | Dual variable domain immunoglobulins and uses thereof |
| RU2603093C2 (ru) * | 2010-04-15 | 2016-11-20 | Дженентек, Инк. | Антитела против полиубиквитина и способы их применения |
| UY33492A (es) * | 2010-07-09 | 2012-01-31 | Abbott Lab | Inmunoglobulinas con dominio variable dual y usos de las mismas |
| JP6400470B2 (ja) * | 2011-05-16 | 2018-10-03 | ジェネロン（シャンハイ）コーポレイション リミテッド | 多重特異性Ｆａｂ融合タンパク質および使用法 |
| US8852599B2 (en) * | 2011-05-26 | 2014-10-07 | Bristol-Myers Squibb Company | Immunoconjugates, compositions for making them, and methods of making and use |
| MX2014001238A (es) * | 2011-08-05 | 2014-09-22 | Genentech Inc | Anticuerpos contra poliubiquitina y métodos de uso. |
| HK1221908A1 (zh) * | 2013-04-29 | 2017-06-16 | Adimab, Llc | 多特异(polyspecificity)试剂，其制备方法和用途 |
| US10647768B2 (en) * | 2014-05-29 | 2020-05-12 | Macrogenics, Inc. | Multi-chain polypeptide-containing tri-specific binding molecules |
| WO2016077505A2 (en) * | 2014-11-11 | 2016-05-19 | Amunix Operating Inc. | Targeted xten conjugate compositions and methods of making same |
| US20180016346A1 (en) * | 2015-01-08 | 2018-01-18 | Kyowa Hakko Kirin Co., Ltd | Bispecific antibody binding to trailr2 and psma |
| WO2016115274A1 (en) * | 2015-01-14 | 2016-07-21 | Compass Therapeutics Llc | Multispecific immunomodulatory antigen-binding constructs |
| CN107530424A (zh) * | 2015-02-20 | 2018-01-02 | 俄亥俄州国家创新基金会 | 针对nkg2d和肿瘤相关抗原的二价抗体 |
| WO2016135041A1 (en) * | 2015-02-26 | 2016-09-01 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Fusion proteins and antibodies comprising thereof for promoting apoptosis |
| SG11201708257UA (en) * | 2015-04-06 | 2017-11-29 | Subdomain Llc | De novo binding domain containing polypeptides and uses thereof |
| JP6840682B2 (ja) * | 2015-06-23 | 2021-03-10 | イナート・ファルマ・ソシエテ・アノニムＩｎｎａｔｅ Ｐｈａｒｍａ Ｐｈａｒｍａ Ｓ．Ａ． | 多重特異的抗原結合タンパク質 |
-
2018
- 2018-02-10 CA CA3053275A patent/CA3053275A1/en active Pending
- 2018-02-10 AU AU2018217834A patent/AU2018217834A1/en not_active Abandoned
- 2018-02-10 KR KR1020197026585A patent/KR20190120770A/ko not_active Withdrawn
- 2018-02-10 SG SG11201907271PA patent/SG11201907271PA/en unknown
- 2018-02-10 US US16/483,788 patent/US20200024353A1/en not_active Abandoned
- 2018-02-10 MX MX2019009541A patent/MX2019009541A/es unknown
- 2018-02-10 EP EP18751484.9A patent/EP3579878A4/en not_active Withdrawn
- 2018-02-10 CN CN201880024146.6A patent/CN110913902A/zh active Pending
- 2018-02-10 JP JP2019543270A patent/JP2020507577A/ja not_active Withdrawn
- 2018-02-10 WO PCT/US2018/017718 patent/WO2018148610A1/en not_active Ceased
- 2018-02-10 RU RU2019128204A patent/RU2019128204A/ru unknown
- 2018-02-10 BR BR112019016553-3A patent/BR112019016553A2/pt not_active Application Discontinuation
-
2019
- 2019-08-07 IL IL268574A patent/IL268574A/en unknown
-
2022
- 2022-04-28 JP JP2022074378A patent/JP2022105121A/ja not_active Withdrawn
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