JP2015522525A5 - - Google Patents
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- JP2015522525A5 JP2015522525A5 JP2015510588A JP2015510588A JP2015522525A5 JP 2015522525 A5 JP2015522525 A5 JP 2015522525A5 JP 2015510588 A JP2015510588 A JP 2015510588A JP 2015510588 A JP2015510588 A JP 2015510588A JP 2015522525 A5 JP2015522525 A5 JP 2015522525A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- monomeric
- polypeptide comprises
- acid mutations
- polypeptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261645555P | 2012-05-10 | 2012-05-10 | |
| US61/645,555 | 2012-05-10 | ||
| PCT/CA2013/000471 WO2013166594A1 (en) | 2012-05-10 | 2013-05-10 | Heteromultimer constructs of immunoglobulin heavy chains with mutations in the fc domain |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015522525A JP2015522525A (ja) | 2015-08-06 |
| JP2015522525A5 true JP2015522525A5 (enExample) | 2016-06-23 |
| JP6351572B2 JP6351572B2 (ja) | 2018-07-04 |
Family
ID=49550021
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015510588A Active JP6351572B2 (ja) | 2012-05-10 | 2013-05-10 | Fcドメインに突然変異を有する免疫グロブリン重鎖のヘテロ多量体構築物 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US20130336973A1 (enExample) |
| EP (1) | EP2847230B1 (enExample) |
| JP (1) | JP6351572B2 (enExample) |
| AU (1) | AU2013258834B2 (enExample) |
| CA (1) | CA2872540A1 (enExample) |
| ES (1) | ES2843054T3 (enExample) |
| WO (1) | WO2013166594A1 (enExample) |
Families Citing this family (85)
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| US9499634B2 (en) | 2012-06-25 | 2016-11-22 | Zymeworks Inc. | Process and methods for efficient manufacturing of highly pure asymmetric antibodies in mammalian cells |
| JP6498601B2 (ja) | 2012-07-13 | 2019-04-10 | ザイムワークス,インコーポレイテッド | 多価ヘテロ多量体足場設計および構築物 |
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| US10077298B2 (en) | 2012-11-28 | 2018-09-18 | Zymeworks Inc. | Engineered immunoglobulin heavy chain-light chain pairs and uses thereof |
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-
2013
- 2013-05-10 WO PCT/CA2013/000471 patent/WO2013166594A1/en not_active Ceased
- 2013-05-10 ES ES13788302T patent/ES2843054T3/es active Active
- 2013-05-10 JP JP2015510588A patent/JP6351572B2/ja active Active
- 2013-05-10 US US13/892,198 patent/US20130336973A1/en not_active Abandoned
- 2013-05-10 EP EP13788302.1A patent/EP2847230B1/en active Active
- 2013-05-10 CA CA2872540A patent/CA2872540A1/en not_active Abandoned
- 2013-05-10 AU AU2013258834A patent/AU2013258834B2/en active Active
-
2016
- 2016-01-06 US US14/989,648 patent/US20160257763A1/en not_active Abandoned
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