JP2021035366A5 - - Google Patents
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- JP2021035366A5 JP2021035366A5 JP2020173659A JP2020173659A JP2021035366A5 JP 2021035366 A5 JP2021035366 A5 JP 2021035366A5 JP 2020173659 A JP2020173659 A JP 2020173659A JP 2020173659 A JP2020173659 A JP 2020173659A JP 2021035366 A5 JP2021035366 A5 JP 2021035366A5
- Authority
- JP
- Japan
- Prior art keywords
- antigen
- protein
- cell
- receptor
- homing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022161320A JP2023011593A (ja) | 2014-08-12 | 2022-10-06 | リンパ節のｂ細胞領域、皮膚、または消化管にホーミングするように操作されたｃａｒ－ｔ細胞 |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462036447P | 2014-08-12 | 2014-08-12 | |
| US62/036,447 | 2014-08-12 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017507842A Division JP2017524365A (ja) | 2014-08-12 | 2015-08-11 | リンパ節のｂ細胞領域、皮膚、または腸管にホーミングするように操作されたｃａｒ−ｔ細胞 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022161320A Division JP2023011593A (ja) | 2014-08-12 | 2022-10-06 | リンパ節のｂ細胞領域、皮膚、または消化管にホーミングするように操作されたｃａｒ－ｔ細胞 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2021035366A JP2021035366A (ja) | 2021-03-04 |
| JP2021035366A5 true JP2021035366A5 (https=) | 2021-06-17 |
Family
ID=55304746
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017507842A Pending JP2017524365A (ja) | 2014-08-12 | 2015-08-11 | リンパ節のｂ細胞領域、皮膚、または腸管にホーミングするように操作されたｃａｒ−ｔ細胞 |
| JP2020173659A Pending JP2021035366A (ja) | 2014-08-12 | 2020-10-15 | リンパ節のｂ細胞領域、皮膚、または消化管にホーミングするように操作されたｃａｒ−ｔ細胞 |
| JP2022161320A Pending JP2023011593A (ja) | 2014-08-12 | 2022-10-06 | リンパ節のｂ細胞領域、皮膚、または消化管にホーミングするように操作されたｃａｒ－ｔ細胞 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017507842A Pending JP2017524365A (ja) | 2014-08-12 | 2015-08-11 | リンパ節のｂ細胞領域、皮膚、または腸管にホーミングするように操作されたｃａｒ−ｔ細胞 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022161320A Pending JP2023011593A (ja) | 2014-08-12 | 2022-10-06 | リンパ節のｂ細胞領域、皮膚、または消化管にホーミングするように操作されたｃａｒ－ｔ細胞 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US20180080008A1 (https=) |
| EP (2) | EP3194579A4 (https=) |
| JP (3) | JP2017524365A (https=) |
| KR (2) | KR20220150428A (https=) |
| CN (1) | CN106795497A (https=) |
| AU (1) | AU2015301921A1 (https=) |
| CA (1) | CA2957929A1 (https=) |
| NZ (1) | NZ729046A (https=) |
| SG (1) | SG11201701111SA (https=) |
| TW (2) | TW201614072A (https=) |
| WO (1) | WO2016025454A2 (https=) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2934532B1 (en) | 2012-12-20 | 2019-10-23 | Purdue Research Foundation | Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics |
| AU2013204922B2 (en) | 2012-12-20 | 2015-05-14 | Celgene Corporation | Chimeric antigen receptors |
| AU2014240083C1 (en) | 2013-03-15 | 2019-10-24 | Celgene Corporation | Modified T lymphocytes |
| CN107995913B (zh) | 2015-05-18 | 2022-02-11 | T细胞受体治疗公司 | 使用融合蛋白对tcr重编程的组合物和方法 |
| JP7282521B2 (ja) | 2016-04-08 | 2023-05-29 | パーデュー・リサーチ・ファウンデイション | Ｃａｒ ｔ細胞療法のための方法および組成物 |
| US11499168B2 (en) | 2016-04-25 | 2022-11-15 | Universitat Basel | Allele editing and applications thereof |
| EP3494138A1 (en) | 2016-08-02 | 2019-06-12 | TCR2 Therapeutics Inc. | Compositions and methods for tcr reprogramming using fusion proteins |
| CA3036745A1 (en) | 2016-10-07 | 2018-04-12 | TCR2 Therapeutics Inc. | Compositions and methods for t-cell receptors reprogramming using fusion proteins |
| WO2018075820A2 (en) | 2016-10-20 | 2018-04-26 | Celgene Corporation | Cereblon-based heterodimerizable chimeric antigen receptors |
| US11851491B2 (en) | 2016-11-22 | 2023-12-26 | TCR2 Therapeutics Inc. | Compositions and methods for TCR reprogramming using fusion proteins |
| AU2018223211B2 (en) * | 2017-02-21 | 2025-02-27 | Adelaide university | T cells expressing chemokine receptors for treating cancer |
| JP7178355B2 (ja) | 2017-02-28 | 2022-11-25 | エンドサイト・インコーポレイテッド | Ｃａｒ ｔ細胞療法のための組成物および方法 |
| US11166985B2 (en) | 2017-05-12 | 2021-11-09 | Crispr Therapeutics Ag | Materials and methods for engineering cells and uses thereof in immuno-oncology |
| MX2019013514A (es) | 2017-05-12 | 2020-01-20 | Crispr Therapeutics Ag | Materiales y metodos para modificar celulas por ingenieria genetica y usos de los mismos en inmunooncologia. |
| US12384830B2 (en) | 2017-06-02 | 2025-08-12 | Regents Of The University Of Minnesota | Compositions and methods for improving immunotherapy |
| CN107287207B (zh) * | 2017-08-01 | 2019-02-26 | 上海优卡迪生物医药科技有限公司 | 一种用于体内示踪和人工清除car-t细胞的标签和应用 |
| WO2019032699A1 (en) * | 2017-08-09 | 2019-02-14 | Eureka Therapeutics, Inc. | CELLS EXPRESSING ANTIBODIES AND CELL SURFACE RECEPTORS |
| WO2019056174A1 (zh) * | 2017-09-19 | 2019-03-28 | 中山大学 | 一种过表达cxcr5的间质干细胞及其制备方法和用途 |
| MX2020007281A (es) * | 2018-01-08 | 2021-01-29 | H Lee Moffitt Cancer Ct & Res | Composiciones y métodos que se dirigen a cánceres que expresan cd99. |
| JP7549303B2 (ja) | 2018-01-22 | 2024-09-11 | エンドサイト・インコーポレイテッド | Ｃａｒ ｔ細胞の使用方法 |
| CN112105382A (zh) | 2018-02-23 | 2020-12-18 | 恩多塞特公司 | 用于car t细胞疗法的顺序方法 |
| US12227763B2 (en) | 2018-05-11 | 2025-02-18 | Crispr Therapeutics Ag | Methods and compositions for treating cancer |
| WO2019241315A1 (en) | 2018-06-12 | 2019-12-19 | Obsidian Therapeutics, Inc. | Pde5 derived regulatory constructs and methods of use in immunotherapy |
| EA202190304A1 (ru) * | 2018-07-18 | 2022-01-21 | Эмджен Инк. | Химерные рецепторы к steap1 и способы их применения |
| CN109666074B (zh) * | 2018-12-29 | 2020-04-24 | 广州百暨基因科技有限公司 | 一种趋化因子受体cxcr5的用途 |
| WO2020182681A1 (en) * | 2019-03-08 | 2020-09-17 | Klinikum Der Universität München | Ccr8 expressing lymphocytes for targeted tumor therapy |
| US20220249558A1 (en) | 2019-04-30 | 2022-08-11 | Crispr Therapeutics Ag | Allogeneic cell therapy of b cell malignancies using genetically engineered t cells targeting cd19 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6534055B1 (en) | 1988-11-23 | 2003-03-18 | Genetics Institute, Inc. | Methods for selectively stimulating proliferation of T cells |
| US6352694B1 (en) | 1994-06-03 | 2002-03-05 | Genetics Institute, Inc. | Methods for inducing a population of T cells to proliferate using agents which recognize TCR/CD3 and ligands which stimulate an accessory molecule on the surface of the T cells |
| US5665577A (en) | 1989-02-06 | 1997-09-09 | Dana-Farber Cancer Institute | Vectors containing HIV packaging sequences, packaging defective HIV vectors, and uses thereof |
| IL104570A0 (en) | 1992-03-18 | 1993-05-13 | Yeda Res & Dev | Chimeric genes and cells transformed therewith |
| US8211422B2 (en) | 1992-03-18 | 2012-07-03 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Chimeric receptor genes and cells transformed therewith |
| US6309853B1 (en) | 1994-08-17 | 2001-10-30 | The Rockfeller University | Modulators of body weight, corresponding nucleic acids and proteins, and diagnostic and therapeutic uses thereof |
| US6692964B1 (en) | 1995-05-04 | 2004-02-17 | The United States Of America As Represented By The Secretary Of The Navy | Methods for transfecting T cells |
| US5948893A (en) | 1996-01-17 | 1999-09-07 | The United States Of America As Represented By The Secretary Of The Navy | Murine hybridoma and antibody binding to CD28 receptor secreted by the hybridoma and method of using the antibody |
| US5994136A (en) | 1997-12-12 | 1999-11-30 | Cell Genesys, Inc. | Method and means for producing high titer, safe, recombinant lentivirus vectors |
| EP1849873B1 (en) | 1999-04-29 | 2011-10-12 | Gbp Ip, Llc | Method and means for producing high titer, safe, recombinant lentivirus vectors |
| EP2316918B1 (en) | 2001-02-14 | 2015-07-01 | Anthrogenesis Corporation | Post-partum mammalian placenta, its use and placental stem cells therefrom |
| US20070155663A1 (en) * | 2003-03-24 | 2007-07-05 | Rudolf Richter | Use of chemokine receptor agonists for stem cell transplantation |
| JP2005336062A (ja) * | 2004-05-24 | 2005-12-08 | Mitsubishi Chemicals Corp | Ｔ細胞の腸組織へのホーミング誘導剤 |
| PL2471907T3 (pl) | 2005-12-29 | 2019-07-31 | Celularity, Inc. | Populacje komórek macierzystych łożyska |
| WO2010003002A2 (en) * | 2008-07-02 | 2010-01-07 | Board Of Regents, The University Of Texas System | Modulation of follicular helper t cells |
| JP6850528B2 (ja) * | 2012-02-13 | 2021-03-31 | シアトル チルドレンズ ホスピタル ドゥーイング ビジネス アズ シアトル チルドレンズ リサーチ インスティテュート | 二重特異性キメラ抗原受容体およびその治療的使用 |
| CN104411819B (zh) * | 2012-06-11 | 2019-05-10 | 威尔逊沃夫制造公司 | 用于过继细胞疗法的改进的细胞培养方法 |
| CN103483452B (zh) * | 2012-06-12 | 2021-08-13 | 上海细胞治疗集团有限公司 | 双信号独立的嵌合抗原受体及其用途 |
| EP2893003B1 (en) * | 2012-09-04 | 2021-03-31 | Inven2 AS | Selective and controlled expansion of educated nk cells |
| US9393268B2 (en) * | 2013-03-15 | 2016-07-19 | Thomas Jefferson University | Cell-based anti-cancer compositions with reduced toxicity and methods of making and using the same |
-
2015
- 2015-08-11 WO PCT/US2015/044611 patent/WO2016025454A2/en not_active Ceased
- 2015-08-11 CA CA2957929A patent/CA2957929A1/en active Pending
- 2015-08-11 KR KR1020227037473A patent/KR20220150428A/ko not_active Ceased
- 2015-08-11 SG SG11201701111SA patent/SG11201701111SA/en unknown
- 2015-08-11 NZ NZ729046A patent/NZ729046A/en not_active IP Right Cessation
- 2015-08-11 EP EP15831772.7A patent/EP3194579A4/en not_active Withdrawn
- 2015-08-11 AU AU2015301921A patent/AU2015301921A1/en not_active Abandoned
- 2015-08-11 CN CN201580055115.3A patent/CN106795497A/zh active Pending
- 2015-08-11 EP EP20195244.7A patent/EP3828267A3/en not_active Withdrawn
- 2015-08-11 KR KR1020177006518A patent/KR20170045244A/ko not_active Ceased
- 2015-08-11 US US15/502,752 patent/US20180080008A1/en not_active Abandoned
- 2015-08-11 JP JP2017507842A patent/JP2017524365A/ja active Pending
- 2015-08-12 TW TW104126314A patent/TW201614072A/zh unknown
- 2015-08-12 TW TW110145417A patent/TW202235619A/zh unknown
-
2020
- 2020-09-30 US US17/039,507 patent/US20210254003A1/en not_active Abandoned
- 2020-10-15 JP JP2020173659A patent/JP2021035366A/ja active Pending
-
2022
- 2022-10-06 JP JP2022161320A patent/JP2023011593A/ja active Pending
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