JP2022515194A5 - - Google Patents

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Publication number
JP2022515194A5
JP2022515194A5 JP2021536031A JP2021536031A JP2022515194A5 JP 2022515194 A5 JP2022515194 A5 JP 2022515194A5 JP 2021536031 A JP2021536031 A JP 2021536031A JP 2021536031 A JP2021536031 A JP 2021536031A JP 2022515194 A5 JP2022515194 A5 JP 2022515194A5
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antigen
pharmaceutical composition
composition according
mage
seq
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JP2021536031A
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Japanese (ja)
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JP7620374B2 (ja
JP2022515194A (ja
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Priority claimed from PCT/US2019/067613 external-priority patent/WO2020132327A1/en
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Priority to JP2024046429A priority Critical patent/JP7843056B2/ja
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JP2021536031A 2018-12-19 2019-12-19 T細胞リンパ腫およびt細胞白血病に対するcd2/5/7ノックアウト抗cd2/5/7キメラ抗原受容体t細胞の使用 Active JP7620374B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024046429A JP7843056B2 (ja) 2018-12-19 2024-03-22 T細胞リンパ腫およびt細胞白血病に対するcd2/5/7ノックアウト抗cd2/5/7キメラ抗原受容体t細胞の使用

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862782131P 2018-12-19 2018-12-19
US62/782,131 2018-12-19
PCT/US2019/067613 WO2020132327A1 (en) 2018-12-19 2019-12-19 Use of cd2/5/7 knock-out anti-cd2/5/7 chimeric antigen receptor t cells against t cell lymphomas and leukemias

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024046429A Division JP7843056B2 (ja) 2018-12-19 2024-03-22 T細胞リンパ腫およびt細胞白血病に対するcd2/5/7ノックアウト抗cd2/5/7キメラ抗原受容体t細胞の使用

Publications (3)

Publication Number Publication Date
JP2022515194A JP2022515194A (ja) 2022-02-17
JP2022515194A5 true JP2022515194A5 (https=) 2022-12-26
JP7620374B2 JP7620374B2 (ja) 2025-01-23

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JP2021536031A Active JP7620374B2 (ja) 2018-12-19 2019-12-19 T細胞リンパ腫およびt細胞白血病に対するcd2/5/7ノックアウト抗cd2/5/7キメラ抗原受容体t細胞の使用
JP2024046429A Active JP7843056B2 (ja) 2018-12-19 2024-03-22 T細胞リンパ腫およびt細胞白血病に対するcd2/5/7ノックアウト抗cd2/5/7キメラ抗原受容体t細胞の使用

Family Applications After (1)

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JP2024046429A Active JP7843056B2 (ja) 2018-12-19 2024-03-22 T細胞リンパ腫およびt細胞白血病に対するcd2/5/7ノックアウト抗cd2/5/7キメラ抗原受容体t細胞の使用

Country Status (11)

Country Link
US (3) US11673964B2 (https=)
EP (1) EP3898692A4 (https=)
JP (2) JP7620374B2 (https=)
KR (1) KR20220002859A (https=)
CN (2) CN113454117B (https=)
AU (1) AU2019404302A1 (https=)
CA (1) CA3124467A1 (https=)
IL (1) IL284196A (https=)
MX (1) MX2021007547A (https=)
SG (1) SG11202106699VA (https=)
WO (1) WO2020132327A1 (https=)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013126729A1 (en) * 2012-02-22 2013-08-29 The Trustees Of The University Of Pennsylvania Use of the cd2 signaling domain in second-generation chimeric antigen receptors
US20170151281A1 (en) 2015-02-19 2017-06-01 Batu Biologics, Inc. Chimeric antigen receptor dendritic cell (car-dc) for treatment of cancer
CN120174005A (zh) 2019-02-13 2025-06-20 比姆医疗股份有限公司 具有用于修饰靶标序列中核碱基的腺苷脱氨酶碱基编辑器的经修饰的免疫细胞
EP4034138A4 (en) 2019-09-27 2024-07-31 Beam Therapeutics, Inc. COMPOSITIONS AND METHODS FOR THE TREATMENT OF LIQUID CANCERS
US10980836B1 (en) 2019-12-11 2021-04-20 Myeloid Therapeutics, Inc. Therapeutic cell compositions and methods of manufacturing and use thereof
WO2022061115A1 (en) * 2020-09-18 2022-03-24 Vor Biopharma Inc. Compositions and methods for cd7 modification
CA3196831A1 (en) * 2020-09-25 2022-03-31 Beam Therapeutics Inc. Fratricide resistant modified immune cells and methods of using the same
WO2022089644A1 (zh) * 2020-11-01 2022-05-05 南京驯鹿医疗技术有限公司 靶向cd5的全人源抗体、全人源嵌合抗原受体(car)及其应用
EP4240367A4 (en) 2020-11-04 2024-10-16 Myeloid Therapeutics, Inc. MODIFIED CHIMERIC FUSION PROTEIN COMPOSITIONS AND METHODS OF USE THEREOF
EP4279508A4 (en) * 2021-01-12 2024-12-04 Nanjing Iaso Biotechnology Co., Ltd. Cd5-targeting fully humanized antibody
KR20230171919A (ko) * 2021-02-11 2023-12-21 더 트러스티스 오브 더 유니버시티 오브 펜실바니아 Ccr4 표적화 키메라 항원 수용체 세포 요법
CN115044617B (zh) * 2021-03-08 2024-08-13 河北森朗生物科技有限公司 Car t细胞的制备方法、car t细胞及其应用
WO2022197949A2 (en) 2021-03-17 2022-09-22 Myeloid Therapeutics, Inc. Engineered chimeric fusion protein compositions and methods of use thereof
BR112023023642A2 (pt) 2021-05-11 2024-01-30 Myeloid Therapeutics Inc Métodos e composições para integração genômica
CN115989244A (zh) * 2021-08-06 2023-04-18 上海驯鹿生物技术有限公司 Cd5和cd7双靶点的全人源嵌合抗原受体(car)及其应用
WO2023114777A2 (en) * 2021-12-14 2023-06-22 The Trustees Of The University Of Pennsylvania Cd5 modified cells comprising chimeric antigen receptors (cars) for treatment of solid tumors
CN114645022B (zh) * 2022-05-13 2022-09-02 首都医科大学宣武医院 靶向CD5的CAR-γ δ T细胞及其制备方法与应用
CN117431217A (zh) * 2022-07-12 2024-01-23 上海驯鹿生物技术有限公司 表达靶向cd5的嵌合抗原受体(car)的细胞及其应用
KR102869461B1 (ko) * 2022-10-05 2025-10-17 주식회사 지씨셀 Cd5를 표적하는 키메라 항원 수용체 및 이를 발현하는 면역세포
EP4716744A2 (en) * 2023-05-23 2026-04-01 Vittoria Biotherapeutics, Inc. Genetically modified cells comprising a heterologous nucleic acid molecule inserted at a cd5 gene locus field
CN121969384A (zh) * 2023-05-31 2026-05-01 维多利亚生物治疗公司 制造t细胞的方法
CN119529071B (zh) * 2023-08-28 2025-11-18 东莞市朋志生物科技有限公司 一种抗登革病毒或其ns1蛋白的抗体及其应用
WO2025122896A1 (en) * 2023-12-08 2025-06-12 The Trustees Of The University Of Pennsylvania Cd5 modified cells comprising heterologous tcrs and methods of using the same
CN118891290A (zh) * 2024-04-12 2024-11-01 科济生物医药(上海)有限公司 细胞免疫疗法的组合物和方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5951983A (en) 1993-03-05 1999-09-14 Universite Catholique De Louvain Methods of inhibiting T cell mediated immune responses with humanized LO-CD2A-specific antibodies
RU2011111640A (ru) 2008-08-29 2012-10-10 Симфоген А/С (Dk) Антитела против cd5
JP2017512304A (ja) * 2014-02-06 2017-05-18 イミューンエクスプレス・プロプライエタリー・リミテッドImmuneXpress Pty Ltd バイオマーカーシグネチャー法ならびにそのための装置およびキット
JP7237449B2 (ja) 2015-02-27 2023-03-13 アイセル・ジーン・セラピューティクス・エルエルシー 血液系腫瘍を標的としたキメラ抗体受容体(CARs)の構成およびその使用方法
WO2017112877A1 (en) 2015-12-22 2017-06-29 Icell Gene Therapeutics, Llc Chimeric antigen receptors and enhancement of anti-tumor activity
KR20230148844A (ko) 2016-03-29 2023-10-25 유니버시티 오브 써던 캘리포니아 암을 표적하는 키메라 항원 수용체
EP3448874A4 (en) * 2016-04-29 2020-04-22 Voyager Therapeutics, Inc. COMPOSITIONS FOR TREATING A DISEASE
EP3548055A4 (en) 2016-12-02 2020-08-19 University of Southern California SYNTHETIC IMMUNE RECEPTORS AND THEIR PROCESSES FOR USE
US10093731B2 (en) * 2017-02-24 2018-10-09 Kindred Biosciences, Inc. Anti-IL31 antibodies for veterinary use
AU2018246377B2 (en) * 2017-03-31 2025-01-30 Cellectis Sa Universal anti-CD22 chimeric antigen receptor engineered immune cells
CA3065126A1 (en) 2017-06-01 2018-12-06 Innovative Cellular Therapeutics CO., LTD. Chimeric antigen receptor cell preparation and uses thereof

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