SG11202106699VA - Use of cd2/5/7 knock-out anti-cd2/5/7 chimeric antigen receptor t cells against t cell lymphomas and leukemias - Google Patents

Use of cd2/5/7 knock-out anti-cd2/5/7 chimeric antigen receptor t cells against t cell lymphomas and leukemias

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Publication number
SG11202106699VA
SG11202106699VA SG11202106699VA SG11202106699VA SG11202106699VA SG 11202106699V A SG11202106699V A SG 11202106699VA SG 11202106699V A SG11202106699V A SG 11202106699VA SG 11202106699V A SG11202106699V A SG 11202106699VA SG 11202106699V A SG11202106699V A SG 11202106699VA
Authority
SG
Singapore
Prior art keywords
leukemias
knock
antigen receptor
chimeric antigen
cell lymphomas
Prior art date
Application number
SG11202106699VA
Inventor
Marco Ruella
Saar Gill
Carl H June
Avery D Posey
Daniel J Powell
Original Assignee
Univ Pennsylvania
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Pennsylvania filed Critical Univ Pennsylvania
Publication of SG11202106699VA publication Critical patent/SG11202106699VA/en

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SG11202106699VA 2018-12-19 2019-12-19 Use of cd2/5/7 knock-out anti-cd2/5/7 chimeric antigen receptor t cells against t cell lymphomas and leukemias SG11202106699VA (en)

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PCT/US2019/067613 WO2020132327A1 (en) 2018-12-19 2019-12-19 Use of cd2/5/7 knock-out anti-cd2/5/7 chimeric antigen receptor t cells against t cell lymphomas and leukemias

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US9783591B2 (en) * 2012-02-22 2017-10-10 The Trustees Of The University Of Pennsylvania Use of the CD2 signaling domain in second-generation chimeric antigen receptors
US20170151281A1 (en) 2015-02-19 2017-06-01 Batu Biologics, Inc. Chimeric antigen receptor dendritic cell (car-dc) for treatment of cancer
EP4214318A1 (en) * 2020-09-18 2023-07-26 Vor Biopharma Inc. Compositions and methods for cd7 modification
CN116685349A (en) * 2020-09-25 2023-09-01 比姆医疗股份有限公司 Modified immune cells resistant to autogenous killing and methods of use thereof
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