CN113454117B - Cd2/5/7敲除抗-cd2/5/7嵌合抗原受体t细胞针对t细胞淋巴瘤和白血病的用途 - Google Patents
Cd2/5/7敲除抗-cd2/5/7嵌合抗原受体t细胞针对t细胞淋巴瘤和白血病的用途 Download PDFInfo
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202510805788.1A CN121059792A (zh) | 2018-12-19 | 2019-12-19 | Cd2/5/7敲除抗-cd2/5/7嵌合抗原受体t细胞针对t细胞淋巴瘤和白血病的用途 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862782131P | 2018-12-19 | 2018-12-19 | |
| US62/782,131 | 2018-12-19 | ||
| PCT/US2019/067613 WO2020132327A1 (en) | 2018-12-19 | 2019-12-19 | Use of cd2/5/7 knock-out anti-cd2/5/7 chimeric antigen receptor t cells against t cell lymphomas and leukemias |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202510805788.1A Division CN121059792A (zh) | 2018-12-19 | 2019-12-19 | Cd2/5/7敲除抗-cd2/5/7嵌合抗原受体t细胞针对t细胞淋巴瘤和白血病的用途 |
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| Publication Number | Publication Date |
|---|---|
| CN113454117A CN113454117A (zh) | 2021-09-28 |
| CN113454117B true CN113454117B (zh) | 2025-07-04 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201980092281.9A Active CN113454117B (zh) | 2018-12-19 | 2019-12-19 | Cd2/5/7敲除抗-cd2/5/7嵌合抗原受体t细胞针对t细胞淋巴瘤和白血病的用途 |
| CN202510805788.1A Pending CN121059792A (zh) | 2018-12-19 | 2019-12-19 | Cd2/5/7敲除抗-cd2/5/7嵌合抗原受体t细胞针对t细胞淋巴瘤和白血病的用途 |
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| CN202510805788.1A Pending CN121059792A (zh) | 2018-12-19 | 2019-12-19 | Cd2/5/7敲除抗-cd2/5/7嵌合抗原受体t细胞针对t细胞淋巴瘤和白血病的用途 |
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| US (3) | US11673964B2 (https=) |
| EP (1) | EP3898692A4 (https=) |
| JP (2) | JP7620374B2 (https=) |
| KR (1) | KR20220002859A (https=) |
| CN (2) | CN113454117B (https=) |
| AU (1) | AU2019404302A1 (https=) |
| CA (1) | CA3124467A1 (https=) |
| IL (1) | IL284196A (https=) |
| MX (1) | MX2021007547A (https=) |
| SG (1) | SG11202106699VA (https=) |
| WO (1) | WO2020132327A1 (https=) |
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| MX2014010185A (es) * | 2012-02-22 | 2014-11-14 | Univ Pennsylvania | Uso de dominio de señalizacion cd2 en receptores de antigeno quimericos de segunda generacion. |
| US20170151281A1 (en) | 2015-02-19 | 2017-06-01 | Batu Biologics, Inc. | Chimeric antigen receptor dendritic cell (car-dc) for treatment of cancer |
| WO2020168122A1 (en) | 2019-02-13 | 2020-08-20 | Beam Therapeutics Inc. | Modified immune cells having adenosine deaminase base editors for modifying a nucleobase in a target sequence |
| EP4034138A4 (en) | 2019-09-27 | 2024-07-31 | Beam Therapeutics, Inc. | COMPOSITIONS AND METHODS FOR THE TREATMENT OF LIQUID CANCERS |
| US10980836B1 (en) | 2019-12-11 | 2021-04-20 | Myeloid Therapeutics, Inc. | Therapeutic cell compositions and methods of manufacturing and use thereof |
| WO2022061115A1 (en) * | 2020-09-18 | 2022-03-24 | Vor Biopharma Inc. | Compositions and methods for cd7 modification |
| AU2021347359A1 (en) * | 2020-09-25 | 2023-05-18 | Beam Therapeutics Inc. | Fratricide resistant modified immune cells and methods of using the same |
| CN116568709A (zh) * | 2020-11-01 | 2023-08-08 | 南京驯鹿生物技术股份有限公司 | 靶向cd5的全人源抗体、全人源嵌合抗原受体(car)及其应用 |
| CA3197423A1 (en) | 2020-11-04 | 2022-05-12 | Daniel Getts | Engineered chimeric fusion protein compositions and methods of use thereof |
| EP4279515A4 (en) * | 2021-01-12 | 2025-02-19 | Nanjing Iaso Biotechnology Co., Ltd. | Fully human single-domain tandem chimeric antigen receptor (car) targeting cd5, and use thereof |
| CA3207861A1 (en) * | 2021-02-11 | 2022-08-18 | Carl H. June | Ccr4-targeting chimeric antigen receptor cell therapy |
| CN115044617B (zh) * | 2021-03-08 | 2024-08-13 | 河北森朗生物科技有限公司 | Car t细胞的制备方法、car t细胞及其应用 |
| EP4308133A4 (en) | 2021-03-17 | 2025-01-22 | Myeloid Therapeutics, Inc. | MANIPULATED CHIMERIC FUSION PROTEIN COMPOSITIONS AND METHODS OF USE THEREOF |
| AU2022272235A1 (en) | 2021-05-11 | 2023-12-21 | Create Medicines, Inc. | Methods and compositions for genomic integration |
| CN115989244A (zh) * | 2021-08-06 | 2023-04-18 | 上海驯鹿生物技术有限公司 | Cd5和cd7双靶点的全人源嵌合抗原受体(car)及其应用 |
| CA3240846A1 (en) * | 2021-12-14 | 2023-06-22 | The Trustees Of The University Of Pennsylvania | Cd5 modified cells comprising chimeric antigen receptors (cars) for treatment of solid tumors |
| CN114645022B (zh) * | 2022-05-13 | 2022-09-02 | 首都医科大学宣武医院 | 靶向CD5的CAR-γ δ T细胞及其制备方法与应用 |
| CN117431217A (zh) * | 2022-07-12 | 2024-01-23 | 上海驯鹿生物技术有限公司 | 表达靶向cd5的嵌合抗原受体(car)的细胞及其应用 |
| KR102869461B1 (ko) * | 2022-10-05 | 2025-10-17 | 주식회사 지씨셀 | Cd5를 표적하는 키메라 항원 수용체 및 이를 발현하는 면역세포 |
| KR20260051108A (ko) * | 2023-05-23 | 2026-04-15 | 비토리아 바이오테라퓨틱스, 인코포레이티드. | Cd5 유전자좌 영역에 삽입된 이종성 핵산 분자를 포함하는 유전자 변형 세포 |
| EP4719467A2 (en) * | 2023-05-31 | 2026-04-08 | Vittoria Biotherapeutics, Inc. | Methods of manufacturing t cells |
| CN119529071B (zh) * | 2023-08-28 | 2025-11-18 | 东莞市朋志生物科技有限公司 | 一种抗登革病毒或其ns1蛋白的抗体及其应用 |
| WO2025122896A1 (en) * | 2023-12-08 | 2025-06-12 | The Trustees Of The University Of Pennsylvania | Cd5 modified cells comprising heterologous tcrs and methods of using the same |
| CN118891290A (zh) * | 2024-04-12 | 2024-11-01 | 科济生物医药(上海)有限公司 | 细胞免疫疗法的组合物和方法 |
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| US5951983A (en) | 1993-03-05 | 1999-09-14 | Universite Catholique De Louvain | Methods of inhibiting T cell mediated immune responses with humanized LO-CD2A-specific antibodies |
| MX2011000970A (es) | 2008-08-29 | 2011-03-15 | Symphogen As | Anticuerpos anti-cd5. |
| US11047010B2 (en) * | 2014-02-06 | 2021-06-29 | Immunexpress Pty Ltd | Biomarker signature method, and apparatus and kits thereof |
| JP7237449B2 (ja) | 2015-02-27 | 2023-03-13 | アイセル・ジーン・セラピューティクス・エルエルシー | 血液系腫瘍を標的としたキメラ抗体受容体(CARs)の構成およびその使用方法 |
| WO2017112877A1 (en) | 2015-12-22 | 2017-06-29 | Icell Gene Therapeutics, Llc | Chimeric antigen receptors and enhancement of anti-tumor activity |
| WO2017172981A2 (en) * | 2016-03-29 | 2017-10-05 | University Of Southern California | Chimeric antigen receptors targeting cancer |
| EP3448874A4 (en) * | 2016-04-29 | 2020-04-22 | Voyager Therapeutics, Inc. | COMPOSITIONS FOR TREATING A DISEASE |
| WO2018156180A1 (en) * | 2017-02-24 | 2018-08-30 | Kindred Biosciences, Inc. | Anti-il31 antibodies for veterinary use |
| EP4414380A3 (en) * | 2017-03-31 | 2024-12-04 | Cellectis SA | Universal anti-cd22 chimeric antigen receptor engineered immune cells |
| CA3065126A1 (en) * | 2017-06-01 | 2018-12-06 | Innovative Cellular Therapeutics CO., LTD. | Chimeric antigen receptor cell preparation and uses thereof |
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| US12227588B2 (en) | 2025-02-18 |
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