JP2020531411A5 - - Google Patents
Info
- Publication number
- JP2020531411A5 JP2020531411A5 JP2020505786A JP2020505786A JP2020531411A5 JP 2020531411 A5 JP2020531411 A5 JP 2020531411A5 JP 2020505786 A JP2020505786 A JP 2020505786A JP 2020505786 A JP2020505786 A JP 2020505786A JP 2020531411 A5 JP2020531411 A5 JP 2020531411A5
- Authority
- JP
- Japan
- Prior art keywords
- poi
- matrix
- protein
- eluate pool
- buffer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762546558P | 2017-08-17 | 2017-08-17 | |
| US62/546,558 | 2017-08-17 | ||
| PCT/US2018/046919 WO2019036626A1 (en) | 2017-08-17 | 2018-08-17 | PROCESS FOR PURIFYING GLYCOSYLATED PROTEIN FROM GALECTINES AND OTHER HOST CELL CONTAMINANTS |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020531411A JP2020531411A (ja) | 2020-11-05 |
| JP2020531411A5 true JP2020531411A5 (https=) | 2022-05-09 |
| JP7097433B2 JP7097433B2 (ja) | 2022-07-07 |
Family
ID=63684424
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020505786A Active JP7097433B2 (ja) | 2017-08-17 | 2018-08-17 | 宿主細胞ガレクチンおよび他の夾雑物からグリコシル化タンパク質を精製する方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US11358983B2 (https=) |
| EP (1) | EP3668985B1 (https=) |
| JP (1) | JP7097433B2 (https=) |
| KR (1) | KR102578087B1 (https=) |
| CN (1) | CN111344410B (https=) |
| CA (1) | CA3067735A1 (https=) |
| DK (1) | DK3668985T3 (https=) |
| ES (1) | ES2887046T3 (https=) |
| MY (1) | MY199833A (https=) |
| WO (1) | WO2019036626A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3668985B1 (en) | 2017-08-17 | 2021-06-16 | Just-Evotec Biologics, Inc. | Method of purifying glycosylated protein from host cell galectins and other contaminants |
| SG11202110968VA (en) | 2019-12-06 | 2021-10-28 | Regeneron Pharma | Anti-vegf protein compositions and methods for producing the same |
| AU2021268026A1 (en) | 2020-05-08 | 2023-01-19 | Regeneron Pharmaceuticals, Inc. | VEGF traps and mini-traps and methods for treating ocular disorders and cancer |
| WO2023192926A2 (en) * | 2022-03-30 | 2023-10-05 | Ionis Pharmaceuticals, Inc. | Methods for separating certain oligonucleotide compounds |
| TW202502843A (zh) * | 2023-03-17 | 2025-01-16 | 日商丸善石油化學股份有限公司 | 聚合物之製造方法 |
Family Cites Families (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USRE30985E (en) | 1978-01-01 | 1982-06-29 | Serum-free cell culture media | |
| US4560655A (en) | 1982-12-16 | 1985-12-24 | Immunex Corporation | Serum-free cell culture medium and process for making same |
| US4657866A (en) | 1982-12-21 | 1987-04-14 | Sudhir Kumar | Serum-free, synthetic, completely chemically defined tissue culture media |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US4767704A (en) | 1983-10-07 | 1988-08-30 | Columbia University In The City Of New York | Protein-free culture medium |
| GB8516415D0 (en) | 1985-06-28 | 1985-07-31 | Celltech Ltd | Culture of animal cells |
| US4927762A (en) | 1986-04-01 | 1990-05-22 | Cell Enterprises, Inc. | Cell culture medium with antioxidant |
| EP0387319B1 (en) | 1988-07-23 | 1996-03-06 | Delta Biotechnology Limited | Secretory leader sequences |
| ATE135397T1 (de) | 1988-09-23 | 1996-03-15 | Cetus Oncology Corp | Zellenzuchtmedium für erhöhtes zellenwachstum, zur erhöhung der langlebigkeit und expression der produkte |
| US5122469A (en) | 1990-10-03 | 1992-06-16 | Genentech, Inc. | Method for culturing Chinese hamster ovary cells to improve production of recombinant proteins |
| US5429746A (en) | 1994-02-22 | 1995-07-04 | Smith Kline Beecham Corporation | Antibody purification |
| AT403989B (de) | 1996-09-16 | 1998-07-27 | Immuno Ag | Verfahren zur herstellung eines plasmaprotein-hältigen arzneimittels |
| DE69738075T2 (de) | 1996-11-27 | 2008-05-21 | Genentech, Inc., South San Francisco | Affinitätsreinigung von polypeptiden an einer protein a-matrix |
| US6022952A (en) | 1998-04-01 | 2000-02-08 | University Of Alberta | Compositions and methods for protein secretion |
| US6660843B1 (en) | 1998-10-23 | 2003-12-09 | Amgen Inc. | Modified peptides as therapeutic agents |
| JP4475814B2 (ja) | 1998-11-20 | 2010-06-09 | 扶桑薬品工業株式会社 | タンパク質発現ベクターとその使用 |
| AU4010400A (en) | 1999-03-18 | 2000-10-04 | Human Genome Sciences, Inc. | 27 human secreted proteins |
| CN101433715B (zh) | 1999-06-08 | 2013-04-17 | 里珍纳龙药品有限公司 | 具有改善的药物动力学特性的修饰嵌合多肽 |
| US7303746B2 (en) | 1999-06-08 | 2007-12-04 | Regeneron Pharmaceuticals, Inc. | Methods of treating eye disorders with modified chimeric polypeptides |
| US7306799B2 (en) | 1999-06-08 | 2007-12-11 | Regeneron Pharmaceuticals, Inc. | Use of VEGF inhibitors for treatment of eye disorders |
| US7070959B1 (en) | 1999-06-08 | 2006-07-04 | Regeneron Pharmaceuticals, Inc. | Modified chimeric polypeptides with improved pharmacokinetic properties |
| CA2473144C (en) | 2002-02-05 | 2013-05-28 | Genentech, Inc. | Protein purification |
| US7427659B2 (en) | 2003-10-24 | 2008-09-23 | Amgen Inc. | Process for purifying proteins in a hydrophobic interaction chromatography flow-through fraction |
| ZA200710330B (en) | 2005-06-17 | 2009-12-30 | Wyeth Corp | Methods of purifying FC region containing proteins |
| FR2894146B1 (fr) | 2005-12-07 | 2008-06-06 | Ifremer | Utilisation d'un polysaccharide excrete par l'espece vibrio diabolicus a des fins d'ingenierie des tissus conjonctifs non mineralises |
| WO2007109163A2 (en) | 2006-03-16 | 2007-09-27 | Amgen Inc | Wash buffer and method of using |
| US7998927B2 (en) | 2006-06-23 | 2011-08-16 | Aegis Therapeutics, Llc | Stabilizing alkylglycoside compositions and methods thereof |
| AU2008206923A1 (en) | 2007-01-17 | 2008-07-24 | Merck Serono S.A. | Process for the purification of Fc-containing proteins |
| AR067536A1 (es) | 2007-07-17 | 2009-10-14 | Hoffmann La Roche | Metodo para obtener una eritropoyetina mono-pegilada en una forma sustancialmente homogenea |
| SG2013061528A (en) * | 2008-08-14 | 2015-03-30 | Merck Sharp & Dohme | Methods for purifying antibodies using protein a affinity chromatography |
| NZ592095A (en) | 2008-10-20 | 2013-01-25 | Abbott Lab | Isolation and purification of il-12 and tnf-alpha antibodies using protein a affinity chromatography |
| BRPI0919879A2 (pt) | 2008-10-29 | 2016-02-16 | Wyeth Llc | métodos para purificação de moléculas de ligação a antígeno de domínio único |
| WO2011038894A1 (en) | 2009-10-01 | 2011-04-07 | F. Hoffmann-La Roche Ag | Protein a chromatography |
| ES2813398T3 (es) * | 2009-10-20 | 2021-03-23 | Abbvie Inc | Aislamiento y purificación de anticuerpos anti-IL-13 usando cromatografía de afinidad a Proteína A |
| ES2982297T3 (es) | 2009-12-18 | 2024-10-15 | Novartis Ag | Método de cromatografía de afinidad |
| SG191071A1 (en) | 2010-12-08 | 2013-07-31 | Amgen Inc | Ion exchange chromatography in the presence of an amino acid |
| TW201823460A (zh) | 2012-05-29 | 2018-07-01 | 美商再生元醫藥公司 | 生產細胞株增強子 |
| MX2016016318A (es) * | 2014-06-13 | 2017-06-12 | Lupin Atlantis Holdings Sa | Proceso para la purificacion de la proteina de fusion. |
| EP3236772A4 (en) * | 2014-12-22 | 2018-10-17 | Alexion Pharmaceuticals, Inc. | Methods of purifying recombinant proteins |
| TW201702380A (zh) * | 2015-02-27 | 2017-01-16 | 再生元醫藥公司 | 宿主細胞蛋白質修飾 |
| EP3885368A1 (en) | 2015-05-12 | 2021-09-29 | Regeneron Pharmaceuticals, Inc. | Multimeric protein purity determination |
| CN106749660B (zh) * | 2016-12-27 | 2020-02-14 | 嘉和生物药业有限公司 | 单克隆抗体下游纯化过程中有效去除宿主蛋白的方法 |
| EP3668985B1 (en) | 2017-08-17 | 2021-06-16 | Just-Evotec Biologics, Inc. | Method of purifying glycosylated protein from host cell galectins and other contaminants |
| JP2022520793A (ja) * | 2019-02-15 | 2022-04-01 | ジャスト－エヴォテック バイオロジックス、インコーポレイテッド | 自動バイオ製造システム、施設、及びプロセス |
-
2018
- 2018-08-17 EP EP18778588.6A patent/EP3668985B1/en active Active
- 2018-08-17 CN CN201880052805.7A patent/CN111344410B/zh active Active
- 2018-08-17 KR KR1020207007328A patent/KR102578087B1/ko active Active
- 2018-08-17 JP JP2020505786A patent/JP7097433B2/ja active Active
- 2018-08-17 MY MYPI2019007631A patent/MY199833A/en unknown
- 2018-08-17 CA CA3067735A patent/CA3067735A1/en active Pending
- 2018-08-17 DK DK18778588.6T patent/DK3668985T3/da active
- 2018-08-17 ES ES18778588T patent/ES2887046T3/es active Active
- 2018-08-17 WO PCT/US2018/046919 patent/WO2019036626A1/en not_active Ceased
- 2018-08-18 US US16/630,458 patent/US11358983B2/en active Active
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