JP2020520680A5 - - Google Patents
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- Publication number
- JP2020520680A5 JP2020520680A5 JP2020515812A JP2020515812A JP2020520680A5 JP 2020520680 A5 JP2020520680 A5 JP 2020520680A5 JP 2020515812 A JP2020515812 A JP 2020515812A JP 2020515812 A JP2020515812 A JP 2020515812A JP 2020520680 A5 JP2020520680 A5 JP 2020520680A5
- Authority
- JP
- Japan
- Prior art keywords
- solution
- preparation
- cells
- concentration
- cryopreservation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 210000004027 cell Anatomy 0.000 claims 17
- 238000002360 preparation method Methods 0.000 claims 17
- 239000000243 solution Substances 0.000 claims 16
- 238000005138 cryopreservation Methods 0.000 claims 13
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 claims 10
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims 10
- 108090000623 proteins and genes Proteins 0.000 claims 8
- 230000001681 protective effect Effects 0.000 claims 7
- 102000004169 proteins and genes Human genes 0.000 claims 7
- 239000007924 injection Substances 0.000 claims 5
- 238000002347 injection Methods 0.000 claims 5
- 238000000034 method Methods 0.000 claims 5
- 239000011780 sodium chloride Substances 0.000 claims 5
- 239000000203 mixture Substances 0.000 claims 4
- 239000003761 preservation solution Substances 0.000 claims 3
- 210000001744 T-lymphocyte Anatomy 0.000 claims 2
- 230000001172 regenerating effect Effects 0.000 claims 2
- 150000001413 amino acids Chemical class 0.000 claims 1
- 125000000118 dimethyl group Chemical group [H]C([H])([H])* 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000000825 pharmaceutical preparation Substances 0.000 claims 1
- 229940127557 pharmaceutical product Drugs 0.000 claims 1
- 229920000867 polyelectrolyte Polymers 0.000 claims 1
- 210000004986 primary T-cell Anatomy 0.000 claims 1
- 239000008354 sodium chloride injection Substances 0.000 claims 1
- 210000000130 stem cell Anatomy 0.000 claims 1
- 150000003462 sulfoxides Chemical class 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710375424.XA CN108925548A (zh) | 2017-05-24 | 2017-05-24 | 一种冻存细胞制剂及细胞复苏方式 |
| CN201710375424.X | 2017-05-24 | ||
| PCT/CN2018/088246 WO2018214943A1 (zh) | 2017-05-24 | 2018-05-24 | 一种冻存细胞制剂及细胞复苏方式 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020520680A JP2020520680A (ja) | 2020-07-16 |
| JP2020520680A5 true JP2020520680A5 (enExample) | 2021-07-26 |
| JP7303184B2 JP7303184B2 (ja) | 2023-07-04 |
Family
ID=64396262
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020515812A Active JP7303184B2 (ja) | 2017-05-24 | 2018-05-24 | 凍結保存細胞製剤および細胞再生方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20200170242A1 (enExample) |
| EP (1) | EP3632207A4 (enExample) |
| JP (1) | JP7303184B2 (enExample) |
| KR (1) | KR102350423B1 (enExample) |
| CN (1) | CN108925548A (enExample) |
| AU (1) | AU2018272688B2 (enExample) |
| NZ (1) | NZ759568A (enExample) |
| WO (1) | WO2018214943A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110679588A (zh) * | 2019-10-23 | 2020-01-14 | 厦门生命互联科技有限公司 | 一种嵌合抗原受体t细胞冻存介质及用途 |
| AU2021245671A1 (en) * | 2020-03-31 | 2022-10-20 | Cell Exosome Therapeutics Inc. | Cell preservation method |
| AU2021324669A1 (en) * | 2020-08-10 | 2023-02-23 | Angiocrine Bioscience, Inc. | Cryopreserved endothelial cell compositions |
| TW202245811A (zh) * | 2021-02-03 | 2022-12-01 | 美商異基因治療有限公司 | 用於car t細胞藥物產品的調配物與製程 |
| US20220354108A1 (en) * | 2021-05-04 | 2022-11-10 | Tissue Testing Technologies Llc | Preservation methods using trehalose with other cryoprotectants being absent from the cryopreservation protocol |
| CN113994951A (zh) * | 2021-11-17 | 2022-02-01 | 晋文娟 | 一种cik细胞冻存液及冻存方法 |
| CN114097771B (zh) * | 2021-12-15 | 2022-10-14 | 珠海贝索细胞科学技术有限公司 | 一种细胞保存液及其应用和细胞保存方法 |
| CN115136955A (zh) * | 2022-08-03 | 2022-10-04 | 深圳宾德生物技术有限公司 | 细胞冻存液及其制备方法和应用 |
| CN116058363B (zh) * | 2023-01-13 | 2025-10-28 | 杭州中赢生物医疗科技有限公司 | 一种增加nk细胞冻存复苏后活性的方法及其应用 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6713245B2 (en) * | 1998-07-06 | 2004-03-30 | Diacrin, Inc. | Methods for storing neural cells such that they are suitable for transplantation |
| US20030054331A1 (en) * | 2001-09-14 | 2003-03-20 | Stemsource, Inc. | Preservation of non embryonic cells from non hematopoietic tissues |
| US7270946B2 (en) * | 2002-10-04 | 2007-09-18 | Organ Recovery Systems, Inc. | Method for treatment of cellular materials with sugars prior to preservation |
| US7176022B2 (en) * | 2002-12-20 | 2007-02-13 | Cell Genesys, Inc. | Directly injectable formulations which provide enhanced cryoprotection of cell products |
| US20070025961A1 (en) | 2003-06-03 | 2007-02-01 | Kenzo Bamba | Composition for stabilizing survival of transplanted hematopoietic stem cell, kit for obtaining the composition, method of stabilizing survival of transplanted hematopoietic stem cell, human monoclonal antibody or human polyclonal antibody and method of producing the same, gene encoding human monoclonal antibody and transf |
| CN102119936B (zh) * | 2011-03-07 | 2012-12-12 | 李荣旗 | 制备利用人羊膜间充质细胞治疗缺血性脑损伤注射液的方法及其注射液 |
| CN103461322B (zh) * | 2012-06-07 | 2016-08-03 | 西比曼生物科技(上海)有限公司 | 用于冻存复苏后的细胞的保存液 |
| CN102907416B (zh) * | 2012-08-01 | 2016-08-03 | 西比曼生物科技(上海)有限公司 | 一种可维持细胞活性的组织冻存液 |
| CN102792947B (zh) * | 2012-09-03 | 2014-03-26 | 四川新生命干细胞科技股份有限公司 | 一种间充质干细胞冻存液及注射液 |
| CN102908364A (zh) * | 2012-11-14 | 2013-02-06 | 青岛奥克生物开发有限公司 | 一种间充质干细胞注射液及其制备方法和在制备治疗儿童扩张型心肌病药物中的应用 |
| EP3066193B1 (en) | 2013-11-04 | 2024-07-10 | Isopogen Pty Ltd | Cell culture method |
| CN114540266A (zh) | 2014-07-07 | 2022-05-27 | 塔尔加泽梅股份有限公司 | 用于治疗用途的岩藻糖基化细胞的制备和冷冻干燥 |
| CN104430301A (zh) * | 2014-11-18 | 2015-03-25 | 成都康华生物制品有限公司 | 一种提高人二倍体细胞存活率的方法 |
| US20180116956A1 (en) * | 2015-04-02 | 2018-05-03 | Stegi-Ra Trust | Composition for use in treating celiac disease |
| CN104873542A (zh) * | 2015-05-21 | 2015-09-02 | 北京青藤谷禧干细胞科技研究院有限公司 | 一种脐带间充质干细胞注射液及其制备方法和应用 |
| CN104857022A (zh) * | 2015-05-21 | 2015-08-26 | 北京青藤谷禧干细胞科技研究院有限公司 | 一种间充质干细胞注射液、制备方法及其应用 |
| CN105394026B (zh) * | 2015-10-31 | 2017-09-29 | 北京军科联合干细胞生物科技有限公司 | 一种造血干细胞冻存新方法 |
| CN105325402A (zh) * | 2015-11-13 | 2016-02-17 | 黄林海 | 一种用于玻璃化冻存骨髓间充质干细胞的冻存保护剂 |
| CN105477017A (zh) * | 2015-12-03 | 2016-04-13 | 深圳爱生再生医学科技有限公司 | 治疗糖尿病足的混合干细胞制剂及其制备方法 |
| CN105660606B (zh) * | 2016-03-10 | 2018-04-03 | 广州赛莱拉干细胞科技股份有限公司 | 一种细胞冻存液 |
| CN106177918A (zh) * | 2016-09-30 | 2016-12-07 | 广州赛莱拉干细胞科技股份有限公司 | 一种间充质干细胞注射液及其制备方法和应用 |
| US11666649B2 (en) * | 2016-10-11 | 2023-06-06 | University Of Miami | Vectors and vaccine cells for immunity against Zika virus |
| CN106665560B (zh) * | 2017-01-16 | 2021-02-05 | 哈尔滨医科大学 | 一种直接静脉回输的免疫细胞冻存液及其应用 |
-
2017
- 2017-05-24 CN CN201710375424.XA patent/CN108925548A/zh active Pending
-
2018
- 2018-05-24 EP EP18805534.7A patent/EP3632207A4/en not_active Withdrawn
- 2018-05-24 KR KR1020197038096A patent/KR102350423B1/ko active Active
- 2018-05-24 NZ NZ759568A patent/NZ759568A/en unknown
- 2018-05-24 JP JP2020515812A patent/JP7303184B2/ja active Active
- 2018-05-24 US US16/616,216 patent/US20200170242A1/en not_active Abandoned
- 2018-05-24 AU AU2018272688A patent/AU2018272688B2/en active Active
- 2018-05-24 WO PCT/CN2018/088246 patent/WO2018214943A1/zh not_active Ceased
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