JP2020515282A5 - - Google Patents
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- JP2020515282A5 JP2020515282A5 JP2019556410A JP2019556410A JP2020515282A5 JP 2020515282 A5 JP2020515282 A5 JP 2020515282A5 JP 2019556410 A JP2019556410 A JP 2019556410A JP 2019556410 A JP2019556410 A JP 2019556410A JP 2020515282 A5 JP2020515282 A5 JP 2020515282A5
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611246563.4 | 2016-12-29 | ||
| CN201611246563.4A CN108250301A (zh) | 2016-12-29 | 2016-12-29 | 一种多靶点嵌合抗原受体 |
| PCT/CN2017/118980 WO2018121604A1 (zh) | 2016-12-29 | 2017-12-27 | 一种多靶点嵌合抗原受体 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020515282A JP2020515282A (ja) | 2020-05-28 |
| JP2020515282A5 true JP2020515282A5 (enExample) | 2021-07-29 |
Family
ID=62707871
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019556410A Pending JP2020515282A (ja) | 2016-12-29 | 2017-12-27 | 多標的キメラ抗原受容体 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20220064595A1 (enExample) |
| EP (1) | EP3575325A4 (enExample) |
| JP (1) | JP2020515282A (enExample) |
| CN (2) | CN108250301A (enExample) |
| WO (1) | WO2018121604A1 (enExample) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108395482B (zh) | 2017-02-08 | 2021-02-05 | 西比曼生物科技（香港）有限公司 | 一种靶向cd20抗原嵌合抗原受体的构建及其工程化t细胞的活性鉴定 |
| CN110862967A (zh) * | 2018-08-27 | 2020-03-06 | 天津天锐生物科技有限公司 | 一种不依赖细胞因子培养的自然杀伤细胞系silk-nk |
| CN109678965B (zh) * | 2018-10-12 | 2023-04-07 | 中国人民解放军总医院 | 嵌合抗原受体及其基因和重组表达载体、cd22-cd19双靶向性的t细胞及其应用 |
| CN109468283A (zh) * | 2018-11-30 | 2019-03-15 | 北京美康基免生物科技有限公司 | 一种基于cd19和bcma的双重嵌合抗原受体基因修饰的免疫细胞及其应用 |
| CN109485734B (zh) * | 2018-12-30 | 2020-05-12 | 广州百暨基因科技有限公司 | 一种靶向bcma和cd19的双特异性嵌合抗原受体及其应用 |
| CN113474012B (zh) * | 2019-01-25 | 2023-09-08 | 湖南远泰生物技术有限公司 | Epcam抗体和epcam-car-t细胞 |
| CN113710697A (zh) * | 2019-03-15 | 2021-11-26 | 美国政府(由卫生和人类服务部的部长所代表) | 嵌合衔接子和激酶信号传导蛋白及其在免疫疗法中的用途 |
| KR20220019806A (ko) * | 2019-06-12 | 2022-02-17 | 씨에스엘 이노베이션 피티와이 엘티디 | 가용성 보체 수용체 1형 변이체 접합체 및 이의 용도 |
| CN118165120A (zh) * | 2019-07-22 | 2024-06-11 | 南京助天中科科技发展有限公司 | 一种嵌合抗原受体及其应用 |
| WO2021127184A1 (en) * | 2019-12-17 | 2021-06-24 | The Johns Hopkins University | MANAbodies TARGETING TUMOR ANTIGENS AND METHODS OF USING |
| CN113402612A (zh) | 2020-03-17 | 2021-09-17 | 西比曼生物科技（香港）有限公司 | 靶向cd19和cd20的联合嵌合抗原受体及其应用 |
| CN113461824A (zh) * | 2020-03-31 | 2021-10-01 | 普米斯生物技术(珠海)有限公司 | 一种构建多特异性抗体的平台 |
| CN113493524A (zh) * | 2020-04-03 | 2021-10-12 | 重庆精准生物技术有限公司 | 双特异性嵌合抗原受体及其应用 |
| CN111411085A (zh) * | 2020-04-10 | 2020-07-14 | 格源致善(上海)生物科技有限公司 | 一种嵌合抗原受体t细胞及其应用 |
| CN113603787B (zh) * | 2020-05-04 | 2023-05-23 | 英诺康生物医药科技(广州)有限公司 | 一种非分泌型的人白细胞介素15及应用 |
| CN111748044B (zh) * | 2020-07-31 | 2022-02-18 | 广东昭泰体内生物医药科技有限公司 | Cd19和pd-l1双靶点嵌合抗原受体及其应用 |
| CN111848820B (zh) * | 2020-07-31 | 2022-05-17 | 广东昭泰体内生物医药科技有限公司 | Cd19和bcma双靶点嵌合抗原受体及其应用 |
| CN112877346B (zh) * | 2020-08-12 | 2023-01-03 | 山东兴瑞生物科技有限公司 | 抗b7-h3嵌合抗原受体的编码基因、制备方法、具有该基因的质粒、免疫细胞及其应用 |
| CN113234685A (zh) * | 2021-05-25 | 2021-08-10 | 临沂大学 | 一种双靶点cd19/cd20联用嵌合抗原受体t细胞及其制备方法和应用 |
| CN115491359B (zh) * | 2021-06-18 | 2026-03-17 | 南京北恒生物科技有限公司 | 靶向cd30和bcma的工程化免疫细胞 |
| CN114149978B (zh) * | 2022-02-09 | 2022-04-26 | 深圳博雅感知药业有限公司 | 制备car-t细胞的方法 |
| CN114634580B (zh) * | 2022-03-21 | 2024-01-30 | 皖南医学院第一附属医院（皖南医学院弋矶山医院） | 一种膜锚定式il-15超级复合物的研制及其在肿瘤免疫细胞治疗中的应用 |
| CN114478806B (zh) * | 2022-04-14 | 2022-07-01 | 呈诺再生医学科技(北京)有限公司 | 一种提升免疫细胞杀伤活性的嵌合受体及其应用 |
| CN117024598A (zh) * | 2022-09-26 | 2023-11-10 | 东南大学 | 长效的Meso-B7H3双靶点嵌合抗原受体及其应用 |
| CN120112559A (zh) * | 2022-10-28 | 2025-06-06 | 百奥赛图(北京)医药科技股份有限公司 | 抗wt1/hla抗体及其应用 |
| CN116903757B (zh) * | 2023-07-21 | 2024-09-24 | 杭州荣谷生物科技有限公司 | Cd70纳米抗体和双靶向嵌合抗原受体 |
| CN120647773A (zh) * | 2024-03-14 | 2025-09-16 | 上海恩凯细胞技术有限公司 | 嵌合转换受体及其应用 |
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| EP1777294A1 (en) * | 2005-10-20 | 2007-04-25 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | IL-15Ralpha sushi domain as a selective and potent enhancer of IL-15 action through IL-15Rbeta/gamma, and hyperagonist (IL15Ralpha sushi -IL15) fusion proteins |
| EP2388266B1 (en) * | 2007-05-11 | 2014-04-23 | Altor BioScience Corporation | Fusion molecules and IL-15 variants |
| JP6251570B2 (ja) * | 2010-09-21 | 2017-12-20 | アルター・バイオサイエンス・コーポレーション | 多量体ｉｌ−１５可溶性融合分子並びにその製造及び使用方法 |
| EP2537933A1 (en) * | 2011-06-24 | 2012-12-26 | Institut National de la Santé et de la Recherche Médicale (INSERM) | An IL-15 and IL-15Ralpha sushi domain based immunocytokines |
| EP2814846B1 (en) * | 2012-02-13 | 2020-01-08 | Seattle Children's Hospital d/b/a Seattle Children's Research Institute | Bispecific chimeric antigen receptors and therapeutic uses thereof |
| PL4019041T3 (pl) * | 2012-07-13 | 2023-05-08 | The Trustees Of The University Of Pennsylvania | Kontrola toksyczności wobec aktywności przeciwnowotworowej CAR |
| UY35468A (es) | 2013-03-16 | 2014-10-31 | Novartis Ag | Tratamiento de cáncer utilizando un receptor quimérico de antígeno anti-cd19 |
| EP2997134B1 (en) * | 2013-05-14 | 2020-06-24 | Board of Regents, The University of Texas System | Human application of engineered chimeric antigen receptor (car) t-cells |
| EP3093295B1 (en) * | 2014-01-08 | 2020-05-27 | Shanghai Hengrui Pharmaceutical Co., Ltd. | Il-15 heterogeneous dimer protein and uses thereof |
| WO2015164107A1 (en) * | 2014-04-23 | 2015-10-29 | Emory University | Compositions of gm-csf and interleukin fusions for immune modulation and uses related thereto |
| ES2688035T3 (es) * | 2014-08-29 | 2018-10-30 | Gemoab Monoclonals Gmbh | Receptor de antígeno universal que expresa células inmunes para direccionamiento de antígenos múltiples diversos, procedimiento para fabricación del mismo y utilización del mismo para tratamiento de cáncer, infecciones y enfermedades autoinmunes |
| EP3250602A1 (en) * | 2015-01-26 | 2017-12-06 | Cellectis | T cell receptor knock out engineered immune cells, endowed with chimeric antigen receptors binding to cd123 for the treatment of relapsed/refractory acute myeloid lymphoma or blastic plasmacytoid dendritic cell neoplasm |
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2016
- 2016-12-29 CN CN201611246563.4A patent/CN108250301A/zh active Pending
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2017
- 2017-12-27 EP EP17886078.9A patent/EP3575325A4/en not_active Withdrawn
- 2017-12-27 WO PCT/CN2017/118980 patent/WO2018121604A1/zh not_active Ceased
- 2017-12-27 JP JP2019556410A patent/JP2020515282A/ja active Pending
- 2017-12-27 US US16/475,030 patent/US20220064595A1/en not_active Abandoned
- 2017-12-27 CN CN201780029218.1A patent/CN109153730B/zh active Active
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