JP2023514232A5 - - Google Patents

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Publication number
JP2023514232A5
JP2023514232A5 JP2022548920A JP2022548920A JP2023514232A5 JP 2023514232 A5 JP2023514232 A5 JP 2023514232A5 JP 2022548920 A JP2022548920 A JP 2022548920A JP 2022548920 A JP2022548920 A JP 2022548920A JP 2023514232 A5 JP2023514232 A5 JP 2023514232A5
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JP
Japan
Prior art keywords
domain
antigen
item
nucleic acid
car
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022548920A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023514232A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/018027 external-priority patent/WO2021163616A1/en
Publication of JP2023514232A publication Critical patent/JP2023514232A/ja
Publication of JP2023514232A5 publication Critical patent/JP2023514232A5/ja
Pending legal-status Critical Current

Links

JP2022548920A 2020-02-14 2021-02-12 Cd2活性化を伴うキメラ抗原受容体 Pending JP2023514232A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202062976997P 2020-02-14 2020-02-14
US62/976,997 2020-02-14
US202063109831P 2020-11-04 2020-11-04
US63/109,831 2020-11-04
PCT/US2021/018027 WO2021163616A1 (en) 2020-02-14 2021-02-12 Chimeric antigen receptors with cd2 activation

Publications (2)

Publication Number Publication Date
JP2023514232A JP2023514232A (ja) 2023-04-05
JP2023514232A5 true JP2023514232A5 (enExample) 2024-02-21

Family

ID=77292741

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022548920A Pending JP2023514232A (ja) 2020-02-14 2021-02-12 Cd2活性化を伴うキメラ抗原受容体

Country Status (12)

Country Link
US (1) US20230183312A1 (enExample)
EP (1) EP4103596A4 (enExample)
JP (1) JP2023514232A (enExample)
KR (1) KR20220143057A (enExample)
CN (1) CN115698285A (enExample)
AU (1) AU2021218441A1 (enExample)
BR (1) BR112022014722A2 (enExample)
CA (1) CA3167572A1 (enExample)
GB (1) GB2608729A (enExample)
IL (1) IL295421A (enExample)
MX (1) MX2022009827A (enExample)
WO (1) WO2021163616A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN120174005A (zh) 2019-02-13 2025-06-20 比姆医疗股份有限公司 具有用于修饰靶标序列中核碱基的腺苷脱氨酶碱基编辑器的经修饰的免疫细胞
EP4034138A4 (en) 2019-09-27 2024-07-31 Beam Therapeutics, Inc. COMPOSITIONS AND METHODS FOR THE TREATMENT OF LIQUID CANCERS
CA3196831A1 (en) 2020-09-25 2022-03-31 Beam Therapeutics Inc. Fratricide resistant modified immune cells and methods of using the same
WO2023217796A1 (en) * 2022-05-10 2023-11-16 Miltenyi Biotec B.V. & Co. KG Compositions comprising il-15, il-15 receptor alpha and the intracellular signaling domain of cd2 for immune cell therapy
WO2024091848A2 (en) * 2022-10-25 2024-05-02 The Trustees Of The University Of Pennsylvania Anti-ceacam6 car-t cells for the treatment of ceacam6+ tumors
EP4713467A1 (en) * 2023-05-15 2026-03-25 Umoja Biopharma, Inc. Lentiviral delivery of anti-cd20 chimeric antigen receptors
EP4724486A1 (en) * 2023-06-06 2026-04-15 Molecular Partners AG Recombinant cd2 binding proteins and their use

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050113564A1 (en) * 2003-11-05 2005-05-26 St. Jude Children's Research Hospital Chimeric receptors with 4-1BB stimulatory signaling domain
WO2013126729A1 (en) * 2012-02-22 2013-08-29 The Trustees Of The University Of Pennsylvania Use of the cd2 signaling domain in second-generation chimeric antigen receptors
RU2658485C2 (ru) * 2012-10-24 2018-06-21 Дзе Юнайтед Стейтс Оф Америка, Эз Репрезентед Бай Дзе Секретари, Департмент Оф Хелс Энд Хьюман Сёрвисез Химерные антигенные рецепторы м971
DK4074735T3 (da) * 2014-08-28 2025-07-14 Bioatla Inc Betinget aktive kimæriske antigenreceptorer til modificerede t-celler
HRP20191873T1 (hr) * 2014-12-12 2020-01-24 Bluebird Bio, Inc. Kimerni antigenski receptori
US9777064B2 (en) * 2015-03-17 2017-10-03 Chimera Bioengineering, Inc. Smart CAR devices, DE CAR polypeptides, side CARs and uses thereof
WO2017024318A1 (en) * 2015-08-06 2017-02-09 Dana-Farber Cancer Institute, Inc. Targeted protein degradation to attenuate adoptive t-cell therapy associated adverse inflammatory responses
CN105384825B (zh) * 2015-08-11 2018-06-01 南京传奇生物科技有限公司 一种基于单域抗体的双特异性嵌合抗原受体及其应用
EP3535423B1 (en) * 2016-11-07 2022-01-05 The United States of America, as represented by the Secretary, Department of Health and Human Services Methods for selecting therapy for a cancer patient
EP3568416A4 (en) * 2017-01-13 2020-07-08 Celdara Medical, LLC TIM-1 TARGETED CHIMERIC ANTIGENIC RECEPTORS
EP3615574A4 (en) * 2017-04-26 2021-02-24 Eureka Therapeutics, Inc. SPECIFIC GLYPICAN 3 RECOGNIZING CONSTRUCTS AND THEIR USE
WO2019028051A1 (en) * 2017-07-31 2019-02-07 Lentigen Technology, Inc. COMPOSITIONS AND METHODS FOR TREATING CANCER BY ANTI-CD19 / CD20 IMMUNOTHERAPY
ES2960419T3 (es) * 2017-09-15 2024-03-04 Lentigen Tech Inc Composiciones y métodos de tratamiento de cáncer con inmunoterapia anti-CD19
US12473342B2 (en) * 2018-04-27 2025-11-18 The Trustees Of The University Of Pennsylvania Chimeric antigen receptor T regulatory cells for the treatment of atherosclerosis

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