JP2023514232A5 - - Google Patents
Info
- Publication number
- JP2023514232A5 JP2023514232A5 JP2022548920A JP2022548920A JP2023514232A5 JP 2023514232 A5 JP2023514232 A5 JP 2023514232A5 JP 2022548920 A JP2022548920 A JP 2022548920A JP 2022548920 A JP2022548920 A JP 2022548920A JP 2023514232 A5 JP2023514232 A5 JP 2023514232A5
- Authority
- JP
- Japan
- Prior art keywords
- domain
- antigen
- item
- nucleic acid
- car
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202062976997P | 2020-02-14 | 2020-02-14 | |
| US62/976,997 | 2020-02-14 | ||
| US202063109831P | 2020-11-04 | 2020-11-04 | |
| US63/109,831 | 2020-11-04 | ||
| PCT/US2021/018027 WO2021163616A1 (en) | 2020-02-14 | 2021-02-12 | Chimeric antigen receptors with cd2 activation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023514232A JP2023514232A (ja) | 2023-04-05 |
| JP2023514232A5 true JP2023514232A5 (enExample) | 2024-02-21 |
Family
ID=77292741
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022548920A Pending JP2023514232A (ja) | 2020-02-14 | 2021-02-12 | Ｃｄ２活性化を伴うキメラ抗原受容体 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20230183312A1 (enExample) |
| EP (1) | EP4103596A4 (enExample) |
| JP (1) | JP2023514232A (enExample) |
| KR (1) | KR20220143057A (enExample) |
| CN (1) | CN115698285A (enExample) |
| AU (1) | AU2021218441A1 (enExample) |
| BR (1) | BR112022014722A2 (enExample) |
| CA (1) | CA3167572A1 (enExample) |
| GB (1) | GB2608729A (enExample) |
| IL (1) | IL295421A (enExample) |
| MX (1) | MX2022009827A (enExample) |
| WO (1) | WO2021163616A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12600971B2 (en) | 2019-02-13 | 2026-04-14 | Beam Therapeutics Inc. | Modified immune cells having adenosine deaminase base editors for modifying a nucleobase in a target sequence |
| US12594301B2 (en) | 2019-09-27 | 2026-04-07 | Beam Therapeutics Inc. | Compositions and methods for treatment of liquid cancers |
| AU2021347359A1 (en) | 2020-09-25 | 2023-05-18 | Beam Therapeutics Inc. | Fratricide resistant modified immune cells and methods of using the same |
| US20250295773A1 (en) * | 2022-05-10 | 2025-09-25 | Miltenyi Biotec B.V. & Co. KG | Compositions comprising il-15, il-15 receptor alpha and the intracellular signaling domain of cd2 for immune cell therapy |
| WO2024091848A2 (en) * | 2022-10-25 | 2024-05-02 | The Trustees Of The University Of Pennsylvania | Anti-ceacam6 car-t cells for the treatment of ceacam6+ tumors |
| WO2024238153A1 (en) * | 2023-05-15 | 2024-11-21 | Umoja Biopharma, Inc. | Lentiviral delivery of anti-cd20 chimeric antigen receptors |
| JP2026524079A (ja) * | 2023-06-06 | 2026-07-17 | モレキュラー パートナーズ アクチェンゲゼルシャフト | 組換えｃｄ２結合タンパク質及びその使用 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050113564A1 (en) * | 2003-11-05 | 2005-05-26 | St. Jude Children's Research Hospital | Chimeric receptors with 4-1BB stimulatory signaling domain |
| BR112014020502A2 (pt) * | 2012-02-22 | 2019-09-24 | Univ Pennsylvania | sequência de ácido nucleico isolada, receptor quimérico de antígeno isolado, célula, vetor, e, métodos para estimular uma resposta imune, para fornecer uma imunidade antitumoral, para tratamento de um mamífero, para gerar e para expandir uma população de células - t, e para modular a quantidade de citocina secretada por uma célula -t |
| CN104822705B (zh) * | 2012-10-24 | 2019-07-12 | 美国卫生和人力服务部 | M971嵌合抗原受体 |
| GB201506423D0 (en) * | 2015-04-15 | 2015-05-27 | Tc Biopharm Ltd | Gamma delta T cells and uses thereof |
| DK3186284T3 (da) * | 2014-08-28 | 2022-05-09 | Bioatla Inc | Betinget aktive kimæriske antigenreceptorer til modificerede t-celler |
| US10383929B2 (en) * | 2014-12-12 | 2019-08-20 | Bluebird Bio, Inc. | BCMA chimeric antigen receptors |
| CN107708710A (zh) * | 2015-03-17 | 2018-02-16 | 嵌合体生物工程公司 | Smart CAR装置,DE CAR多肽,Side CAR及其使用 |
| CA2994969A1 (en) * | 2015-08-06 | 2017-02-09 | Dana-Farber Cancer Institute, Inc. | Targeted protein degradation to attenuate adoptive t-cell therapy associated adverse inflammatory responses |
| CN105384825B (zh) * | 2015-08-11 | 2018-06-01 | 南京传奇生物科技有限公司 | 一种基于单域抗体的双特异性嵌合抗原受体及其应用 |
| CN117298260A (zh) * | 2016-09-02 | 2023-12-29 | 莱蒂恩技术公司 | 用DuoCAR治疗癌症的组合物和方法 |
| US11312998B2 (en) * | 2016-11-07 | 2022-04-26 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Methods for selecting therapy for a cancer patient |
| US11541076B2 (en) * | 2017-01-13 | 2023-01-03 | Celdara Medical, Llc | Chimeric antigen receptors targeting TIM-1 |
| EP3615574B1 (en) * | 2017-04-26 | 2026-06-24 | Eureka Therapeutics, Inc. | Constructs specifically recognizing glypican 3 and uses thereof |
| AU2018309735B2 (en) * | 2017-07-31 | 2025-03-13 | Lentigen Technology, Inc. | Compositions and methods for treating cancer with anti-CD19/CD20 immunotherapy |
| JP7035170B2 (ja) * | 2017-09-15 | 2022-03-14 | レンティジェン・テクノロジー・インコーポレイテッド | 抗ｃｄ１９免疫療法によりがんを処置するための組成物および方法 |
| WO2019210207A2 (en) * | 2018-04-27 | 2019-10-31 | The Trustees Of The University Of Pennsylvania | Chimeric antigen receptor t regulatory cells for the treatment of atherosclerosis |
| CN110526983B (zh) * | 2018-05-24 | 2022-02-11 | 北京马力喏生物科技有限公司 | 改良型抗cd19 car-t细胞 |
| GB2569692A (en) * | 2018-10-30 | 2019-06-26 | Tc Biopharm Ltd | T cell antigen receptor chimera |
-
2021
- 2021-02-12 CN CN202180026973.0A patent/CN115698285A/zh active Pending
- 2021-02-12 IL IL295421A patent/IL295421A/en unknown
- 2021-02-12 US US17/904,219 patent/US20230183312A1/en active Pending
- 2021-02-12 EP EP21754453.5A patent/EP4103596A4/en active Pending
- 2021-02-12 MX MX2022009827A patent/MX2022009827A/es unknown
- 2021-02-12 GB GB2213361.5A patent/GB2608729A/en not_active Withdrawn
- 2021-02-12 AU AU2021218441A patent/AU2021218441A1/en active Pending
- 2021-02-12 WO PCT/US2021/018027 patent/WO2021163616A1/en not_active Ceased
- 2021-02-12 JP JP2022548920A patent/JP2023514232A/ja active Pending
- 2021-02-12 KR KR1020227031318A patent/KR20220143057A/ko active Pending
- 2021-02-12 CA CA3167572A patent/CA3167572A1/en active Pending
- 2021-02-12 BR BR112022014722A patent/BR112022014722A2/pt unknown
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