JP2022526720A5 - - Google Patents

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Publication number
JP2022526720A5
JP2022526720A5 JP2021555415A JP2021555415A JP2022526720A5 JP 2022526720 A5 JP2022526720 A5 JP 2022526720A5 JP 2021555415 A JP2021555415 A JP 2021555415A JP 2021555415 A JP2021555415 A JP 2021555415A JP 2022526720 A5 JP2022526720 A5 JP 2022526720A5
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JP
Japan
Prior art keywords
amino acid
acid sequence
seq
car
chimeric antigen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2021555415A
Other languages
English (en)
Japanese (ja)
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JP7735186B2 (ja
JP2022526720A (ja
Filing date
Publication date
Priority claimed from RU2019107136A external-priority patent/RU2742000C2/ru
Application filed filed Critical
Publication of JP2022526720A publication Critical patent/JP2022526720A/ja
Publication of JP2022526720A5 publication Critical patent/JP2022526720A5/ja
Application granted granted Critical
Publication of JP7735186B2 publication Critical patent/JP7735186B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2021555415A 2019-03-13 2020-03-13 キメラ抗原受容体の代替の細胞内シグナル伝達ドメイン Active JP7735186B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
RU2019107136A RU2742000C2 (ru) 2019-03-13 2019-03-13 Выделенный альтернативный внутриклеточный сигнальный домен химерного антигенного рецептора и включающий его химерный антигенный рецептор
RU2019107136 2019-03-13
PCT/RU2020/000136 WO2020185121A2 (ru) 2019-03-13 2020-03-13 Выделенный альтернативный внутриклеточный сигнальный домен химерного антигенного рецептора и включающий его химерный антигенный рецептор

Publications (3)

Publication Number Publication Date
JP2022526720A JP2022526720A (ja) 2022-05-26
JP2022526720A5 true JP2022526720A5 (enExample) 2023-03-17
JP7735186B2 JP7735186B2 (ja) 2025-09-08

Family

ID=72425914

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021555415A Active JP7735186B2 (ja) 2019-03-13 2020-03-13 キメラ抗原受容体の代替の細胞内シグナル伝達ドメイン

Country Status (7)

Country Link
US (1) US12540169B2 (enExample)
EP (1) EP3974444A4 (enExample)
JP (1) JP7735186B2 (enExample)
KR (1) KR20220157861A (enExample)
CN (1) CN114206918A (enExample)
RU (1) RU2742000C2 (enExample)
WO (1) WO2020185121A2 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201713078D0 (en) * 2017-08-15 2017-09-27 Adaptimmune Ltd T Cell Modification
KR20210137085A (ko) 2019-03-05 2021-11-17 엔카르타, 인크. Cd19 유도된 키메라 항원 수용체 및 면역 요법에서 이의 용도
CN116601174A (zh) * 2020-10-12 2023-08-15 索伦托药业有限公司 Cd19定向的嵌合抗原受体构建体
PL4401842T3 (pl) * 2021-09-16 2025-11-24 Aboleris Pharma Domeny wiążące przeciwko ludzkiemu CD45RC i ich zastosowania

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5703055A (en) 1989-03-21 1997-12-30 Wisconsin Alumni Research Foundation Generation of antibodies through lipid mediated DNA delivery
US5399346A (en) 1989-06-14 1995-03-21 The United States Of America As Represented By The Department Of Health And Human Services Gene therapy
US5585362A (en) 1989-08-22 1996-12-17 The Regents Of The University Of Michigan Adenovirus vectors for gene therapy
US5350674A (en) 1992-09-04 1994-09-27 Becton, Dickinson And Company Intrinsic factor - horse peroxidase conjugates and a method for increasing the stability thereof
EP1235842A4 (en) 1999-10-15 2003-04-23 Univ Massachusetts Rna interference pathway genes as tools for targeted genetic interference
US6326193B1 (en) 1999-11-05 2001-12-04 Cambria Biosciences, Llc Insect control agent
WO2001096584A2 (en) 2000-06-12 2001-12-20 Akkadix Corporation Materials and methods for the control of nematodes
US20130266551A1 (en) * 2003-11-05 2013-10-10 St. Jude Children's Research Hospital, Inc. Chimeric receptors with 4-1bb stimulatory signaling domain
US20160145348A1 (en) * 2013-03-14 2016-05-26 Fred Hutchinson Cancer Research Center Compositions and methods to modify cells for therapeutic objectives
SI2997141T1 (sl) * 2013-05-13 2023-04-28 Cellectis CD19 specifični himerni antigenski receptor in njegova uporaba
EP3066118B1 (en) * 2013-11-06 2020-01-08 The U.S.A. as represented by the Secretary, Department of Health and Human Services Alk antibodies, conjugates, and chimeric antigen receptors, and their use
ES2836743T3 (es) * 2014-06-02 2021-06-28 Us Health Receptores de antígeno quiméricos que seleccionan como diana CD-19
PT3393504T (pt) 2015-12-22 2025-12-30 Novartis Ag Recetor de antigénio quimérico (car) de mesotelina e anticorpo contra o inibidor de pd-l1 para utilização combinada em terapia anticancerígena
US11578115B2 (en) * 2017-01-10 2023-02-14 The General Hospital Corporation Chimeric antigen receptors based on alternative signal 1 domains

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