CN115698285A - 具有cd2激活的嵌合抗原受体 - Google Patents

具有cd2激活的嵌合抗原受体 Download PDF

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Publication number
CN115698285A
CN115698285A CN202180026973.0A CN202180026973A CN115698285A CN 115698285 A CN115698285 A CN 115698285A CN 202180026973 A CN202180026973 A CN 202180026973A CN 115698285 A CN115698285 A CN 115698285A
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antigen
domain
car
ser
cell
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Chinese (zh)
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R·G·马兹纳
C·L·麦考尔
A·图斯利
M·蒙耶-戴瑟罗斯
L·拉巴尼
C·蒙特
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Leland Stanford Junior University
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Leland Stanford Junior University
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    • A61K40/41—Vertebrate antigens
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    • A61K40/4202—Receptors, cell surface antigens or cell surface determinants
    • A61K40/4221—CD20
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    • C07K16/2896—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
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CN202180026973.0A 2020-02-14 2021-02-12 具有cd2激活的嵌合抗原受体 Pending CN115698285A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202062976997P 2020-02-14 2020-02-14
US62/976,997 2020-02-14
US202063109831P 2020-11-04 2020-11-04
US63/109,831 2020-11-04
PCT/US2021/018027 WO2021163616A1 (en) 2020-02-14 2021-02-12 Chimeric antigen receptors with cd2 activation

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CN115698285A true CN115698285A (zh) 2023-02-03

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EP (1) EP4103596A4 (enExample)
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KR (1) KR20220143057A (enExample)
CN (1) CN115698285A (enExample)
AU (1) AU2021218441A1 (enExample)
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IL (1) IL295421A (enExample)
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US12600971B2 (en) 2019-02-13 2026-04-14 Beam Therapeutics Inc. Modified immune cells having adenosine deaminase base editors for modifying a nucleobase in a target sequence
US12594301B2 (en) 2019-09-27 2026-04-07 Beam Therapeutics Inc. Compositions and methods for treatment of liquid cancers
AU2021347359A1 (en) 2020-09-25 2023-05-18 Beam Therapeutics Inc. Fratricide resistant modified immune cells and methods of using the same
US20250295773A1 (en) * 2022-05-10 2025-09-25 Miltenyi Biotec B.V. & Co. KG Compositions comprising il-15, il-15 receptor alpha and the intracellular signaling domain of cd2 for immune cell therapy
WO2024091848A2 (en) * 2022-10-25 2024-05-02 The Trustees Of The University Of Pennsylvania Anti-ceacam6 car-t cells for the treatment of ceacam6+ tumors
WO2024238153A1 (en) * 2023-05-15 2024-11-21 Umoja Biopharma, Inc. Lentiviral delivery of anti-cd20 chimeric antigen receptors
JP2026524079A (ja) * 2023-06-06 2026-07-17 モレキュラー パートナーズ アクチェンゲゼルシャフト 組換えcd2結合タンパク質及びその使用

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US20230183312A1 (en) 2023-06-15
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AU2021218441A1 (en) 2022-09-01
IL295421A (en) 2022-10-01
CA3167572A1 (en) 2021-08-19
EP4103596A1 (en) 2022-12-21
EP4103596A4 (en) 2024-09-04
GB202213361D0 (en) 2022-10-26
BR112022014722A2 (pt) 2022-10-11
JP2023514232A (ja) 2023-04-05
WO2021163616A1 (en) 2021-08-19

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