KR20220143057A - Cd2 활성화를 갖는 키메라 항원 수용체 - Google Patents

Cd2 활성화를 갖는 키메라 항원 수용체 Download PDF

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KR20220143057A
KR20220143057A KR1020227031318A KR20227031318A KR20220143057A KR 20220143057 A KR20220143057 A KR 20220143057A KR 1020227031318 A KR1020227031318 A KR 1020227031318A KR 20227031318 A KR20227031318 A KR 20227031318A KR 20220143057 A KR20220143057 A KR 20220143057A
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antigen
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로비 지. 마즈너
크리스탈 엘. 맥콜
에이단 투슬리
미셸 몬제-다이서로스
루아이 라바니
크리스토퍼 마운트
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더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티
더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티
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Publication of KR20220143057A publication Critical patent/KR20220143057A/ko
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KR1020227031318A 2020-02-14 2021-02-12 Cd2 활성화를 갖는 키메라 항원 수용체 Pending KR20220143057A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202062976997P 2020-02-14 2020-02-14
US62/976,997 2020-02-14
US202063109831P 2020-11-04 2020-11-04
US63/109,831 2020-11-04
PCT/US2021/018027 WO2021163616A1 (en) 2020-02-14 2021-02-12 Chimeric antigen receptors with cd2 activation

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KR20220143057A true KR20220143057A (ko) 2022-10-24

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EP (1) EP4103596A4 (enExample)
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CN120174005A (zh) 2019-02-13 2025-06-20 比姆医疗股份有限公司 具有用于修饰靶标序列中核碱基的腺苷脱氨酶碱基编辑器的经修饰的免疫细胞
EP4034138A4 (en) 2019-09-27 2024-07-31 Beam Therapeutics, Inc. COMPOSITIONS AND METHODS FOR THE TREATMENT OF LIQUID CANCERS
CA3196831A1 (en) 2020-09-25 2022-03-31 Beam Therapeutics Inc. Fratricide resistant modified immune cells and methods of using the same
WO2023217796A1 (en) * 2022-05-10 2023-11-16 Miltenyi Biotec B.V. & Co. KG Compositions comprising il-15, il-15 receptor alpha and the intracellular signaling domain of cd2 for immune cell therapy
WO2024091848A2 (en) * 2022-10-25 2024-05-02 The Trustees Of The University Of Pennsylvania Anti-ceacam6 car-t cells for the treatment of ceacam6+ tumors
EP4713467A1 (en) * 2023-05-15 2026-03-25 Umoja Biopharma, Inc. Lentiviral delivery of anti-cd20 chimeric antigen receptors
EP4724486A1 (en) * 2023-06-06 2026-04-15 Molecular Partners AG Recombinant cd2 binding proteins and their use

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WO2013126729A1 (en) * 2012-02-22 2013-08-29 The Trustees Of The University Of Pennsylvania Use of the cd2 signaling domain in second-generation chimeric antigen receptors
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EP3535423B1 (en) * 2016-11-07 2022-01-05 The United States of America, as represented by the Secretary, Department of Health and Human Services Methods for selecting therapy for a cancer patient
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US12473342B2 (en) * 2018-04-27 2025-11-18 The Trustees Of The University Of Pennsylvania Chimeric antigen receptor T regulatory cells for the treatment of atherosclerosis

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GB2608729A (en) 2023-01-11
MX2022009827A (es) 2022-09-05
CA3167572A1 (en) 2021-08-19
CN115698285A (zh) 2023-02-03
GB202213361D0 (en) 2022-10-26
JP2023514232A (ja) 2023-04-05
US20230183312A1 (en) 2023-06-15
EP4103596A1 (en) 2022-12-21
IL295421A (en) 2022-10-01
BR112022014722A2 (pt) 2022-10-11
EP4103596A4 (en) 2024-09-04
WO2021163616A1 (en) 2021-08-19

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