JP2020506916A - 活動性乾癬性関節炎の治療のための抗ｔｎｆ抗体、組成物、及び方法 - Google Patents

活動性乾癬性関節炎の治療のための抗ｔｎｆ抗体、組成物、及び方法 Download PDF

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JP2020506916A
JP2020506916A JP2019540538A JP2019540538A JP2020506916A JP 2020506916 A JP2020506916 A JP 2020506916A JP 2019540538 A JP2019540538 A JP 2019540538A JP 2019540538 A JP2019540538 A JP 2019540538A JP 2020506916 A JP2020506916 A JP 2020506916A
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antibody
tnf
human
composition
antibodies
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Japanese (ja)
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ハリソン，ダイアン，ディー．
シャー，エリザベス，シー．
キム，リー−ライアン
ハン ロ，キム
ハン ロ，キム
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ヤンセン バイオテツク，インコーポレーテツド
ヤンセン バイオテツク，インコーポレーテツド
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Application filed by ヤンセン バイオテツク，インコーポレーテツド, ヤンセン バイオテツク，インコーポレーテツド filed Critical ヤンセン バイオテツク，インコーポレーテツド
Publication of JP2020506916A publication Critical patent/JP2020506916A/ja
Priority to JP2022110247A priority Critical patent/JP2022137167A/ja
Priority to JP2024151883A priority patent/JP2024174927A/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/241—Tumor Necrosis Factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Biochemistry (AREA)
  • Dermatology (AREA)
  • Endocrinology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP2019540538A 2017-01-30 2017-11-16 活動性乾癬性関節炎の治療のための抗ｔｎｆ抗体、組成物、及び方法 Withdrawn JP2020506916A (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2022110247A JP2022137167A (ja) 2017-01-30 2022-07-08 活動性乾癬性関節炎の治療のための抗ｔｎｆ抗体、組成物、及び方法
JP2024151883A JP2024174927A (ja) 2017-01-30 2024-09-04 活動性乾癬性関節炎の治療のための抗ｔｎｆ抗体、組成物、及び方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762452079P 2017-01-30 2017-01-30
US62/452,079 2017-01-30
PCT/US2017/061949 WO2018140121A1 (en) 2017-01-30 2017-11-16 Anti-tnf antibodies, compositions, and methods for the treatment of active psoriatic arthritis

Related Child Applications (2)

Application Number Title Priority Date Filing Date
JP2022110247A Division JP2022137167A (ja) 2017-01-30 2022-07-08 活動性乾癬性関節炎の治療のための抗ｔｎｆ抗体、組成物、及び方法
JP2024151883A Division JP2024174927A (ja) 2017-01-30 2024-09-04 活動性乾癬性関節炎の治療のための抗ｔｎｆ抗体、組成物、及び方法

Publications (1)

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JP2020506916A true JP2020506916A (ja) 2020-03-05

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ID=62977170

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JP2019540538A Withdrawn JP2020506916A (ja) 2017-01-30 2017-11-16 活動性乾癬性関節炎の治療のための抗ｔｎｆ抗体、組成物、及び方法
JP2022110247A Pending JP2022137167A (ja) 2017-01-30 2022-07-08 活動性乾癬性関節炎の治療のための抗ｔｎｆ抗体、組成物、及び方法
JP2024151883A Pending JP2024174927A (ja) 2017-01-30 2024-09-04 活動性乾癬性関節炎の治療のための抗ｔｎｆ抗体、組成物、及び方法

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JP2022110247A Pending JP2022137167A (ja) 2017-01-30 2022-07-08 活動性乾癬性関節炎の治療のための抗ｔｎｆ抗体、組成物、及び方法
JP2024151883A Pending JP2024174927A (ja) 2017-01-30 2024-09-04 活動性乾癬性関節炎の治療のための抗ｔｎｆ抗体、組成物、及び方法

Country Status (12)

Country Link
US (4) US20180215819A1 (https=)
EP (1) EP3573658A4 (https=)
JP (3) JP2020506916A (https=)
KR (2) KR20190113858A (https=)
CN (1) CN110234351A (https=)
AU (1) AU2017396503B2 (https=)
CA (1) CA3052095A1 (https=)
IL (1) IL268007B2 (https=)
MA (1) MA47362A (https=)
MX (1) MX2019008989A (https=)
NZ (2) NZ794353A (https=)
WO (1) WO2018140121A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2023528265A (ja) * 2020-05-21 2023-07-04 ヤンセン バイオテツク，インコーポレーテツド Ｉｌ－２３に対する抗体及びｔｎｆアルファに対する抗体の組み合わせ療法を用いた炎症性腸疾患の治療方法

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018119142A1 (en) 2016-12-21 2018-06-28 Amgen Inc. Anti-tnf alpha antibody formulations
MA54750A (fr) * 2019-01-15 2021-11-24 Janssen Biotech Inc Compositions d'anticorps anti-tnf et procédés pour le traitement de l'arthrite idiopathique juvénile
BR112021014267A2 (pt) * 2019-01-23 2022-02-15 Janssen Biotech Inc Composições de anticorpo anti-tnf e métodos para o tratamento de artrite psoriática
JP7662529B2 (ja) 2019-03-14 2025-04-15 ヤンセン バイオテツク，インコーポレーテツド 抗ｔｎｆ抗体組成物を産生するための方法
CA3133381A1 (en) 2019-03-14 2020-09-17 Janssen Biotech, Inc. Manufacturing methods for producing anti-tnf antibody compositions
KR20210141976A (ko) 2019-03-14 2021-11-23 얀센 바이오테크 인코포레이티드 항-tnf 항체 조성물의 제조 방법
MA56015A (fr) * 2019-06-03 2022-04-06 Janssen Biotech Inc Compositions d'anticorps anti-tnf et méthodes pour le traitement de l'arthrite psoriasique
MX2021014953A (es) * 2019-06-04 2022-01-24 Janssen Biotech Inc Metodo seguro y eficaz para tratar la artritis psoriasica con el anticuerpo especifico anti-il23.
CN113274349A (zh) * 2020-02-20 2021-08-20 百奥泰生物制药股份有限公司 抗TNF-α的抗体制剂及其制备方法和用途
BR112022021766A2 (pt) * 2020-04-27 2022-12-13 Janssen Biotech Inc Materiais e métodos para tratar artrite idiopática juvenil
KR102394378B1 (ko) 2020-10-14 2022-05-03 한림대학교 산학협력단 피부 각질세포에서의 아릴탄화수소 수용체 억제자(AhRR) 과발현 방법
IL309997A (en) * 2021-07-09 2024-03-01 Janssen Biotech Inc Production methods for the production of anti-TNF antibody compositions
AU2022308201A1 (en) 2021-07-09 2024-02-22 Janssen Biotech, Inc. Manufacturing methods for producing anti-tnf antibody compositions

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