JP2020506727A5 - - Google Patents
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- JP2020506727A5 JP2020506727A5 JP2019563679A JP2019563679A JP2020506727A5 JP 2020506727 A5 JP2020506727 A5 JP 2020506727A5 JP 2019563679 A JP2019563679 A JP 2019563679A JP 2019563679 A JP2019563679 A JP 2019563679A JP 2020506727 A5 JP2020506727 A5 JP 2020506727A5
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- Prior art keywords
- cancer
- chimeric protein
- receptor
- mutations
- activity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022165861A JP7605800B2 (ja) | 2017-02-06 | 2022-10-14 | 標的化キメラタンパク質及びその使用 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762454993P | 2017-02-06 | 2017-02-06 | |
| US62/454,993 | 2017-02-06 | ||
| PCT/EP2018/052814 WO2018141964A1 (en) | 2017-02-06 | 2018-02-05 | Targeted chimeric proteins and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022165861A Division JP7605800B2 (ja) | 2017-02-06 | 2022-10-14 | 標的化キメラタンパク質及びその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020506727A JP2020506727A (ja) | 2020-03-05 |
| JP2020506727A5 true JP2020506727A5 (https=) | 2021-03-18 |
| JP7476467B2 JP7476467B2 (ja) | 2024-05-01 |
Family
ID=61274224
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019563679A Active JP7476467B2 (ja) | 2017-02-06 | 2018-02-05 | 標的化キメラタンパク質及びその使用 |
| JP2022165861A Active JP7605800B2 (ja) | 2017-02-06 | 2022-10-14 | 標的化キメラタンパク質及びその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022165861A Active JP7605800B2 (ja) | 2017-02-06 | 2022-10-14 | 標的化キメラタンパク質及びその使用 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US11384154B2 (https=) |
| EP (1) | EP3577133A1 (https=) |
| JP (2) | JP7476467B2 (https=) |
| KR (1) | KR102642385B1 (https=) |
| CN (1) | CN110546160A (https=) |
| AU (1) | AU2018216032B2 (https=) |
| CA (1) | CA3052523A1 (https=) |
| IL (1) | IL268346B2 (https=) |
| MX (1) | MX2019009255A (https=) |
| WO (1) | WO2018141964A1 (https=) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN109563141A (zh) * | 2016-05-13 | 2019-04-02 | 奥里尼斯生物科学公司 | 对非细胞结构的治疗性靶向 |
| EP3577133A1 (en) * | 2017-02-06 | 2019-12-11 | Orionis Biosciences NV | Targeted chimeric proteins and uses thereof |
| US12091463B2 (en) | 2017-08-09 | 2024-09-17 | Orionis Biosciences, Inc. | Clec9A binding agents comprising a recombinant heavy-chain only antibody (VHH) |
| JP7423511B2 (ja) | 2017-08-09 | 2024-01-29 | オリオンズ バイオサイエンス インコーポレイテッド | Ｐｄ－１およびｐｄ－ｌ１結合物質 |
| EP3665201A4 (en) | 2017-08-09 | 2021-06-02 | Orionis Biosciences, Inc. | CD8 BINDERS |
| JP2021513361A (ja) | 2018-02-05 | 2021-05-27 | オリオニス バイオサイエンシーズ，インコーポレイテッド | 線維芽細胞結合物質およびその使用 |
| WO2020033646A1 (en) | 2018-08-08 | 2020-02-13 | Orionis Biosciences, Inc. | SIRP1α TARGETED CHIMERIC PROTEINS AND USES THEREOF |
| AU2019353367A1 (en) * | 2018-10-02 | 2021-02-18 | Mitsubishi Tanabe Pharma Corporation | Bi-specific binding agents targeting syndecan-1 and fibroblast growth factor receptor |
| CN113286613A (zh) * | 2018-10-29 | 2021-08-20 | Umc乌得勒支控股有限公司 | IgA介导的通过中性粒细胞的CD47-SIRPα检查点抑制对异常细胞的杀伤 |
| US12410225B2 (en) | 2018-11-08 | 2025-09-09 | Orionis Biosciences, Inc | Modulation of dendritic cell lineages |
| EP3880239A4 (en) | 2018-11-14 | 2022-11-23 | Arch Oncology, Inc. | THERAPEUTIC SIRPalpha ANTIBODIES |
| CN120590542A (zh) | 2019-03-28 | 2025-09-05 | 奥里尼斯生物科学股份有限公司 | 基于clec9a的嵌合蛋白复合物 |
| CA3133648A1 (en) | 2019-03-28 | 2020-10-01 | Orionis Biosciences, Inc. | Fibroblast activation protein binding agents and use thereof |
| JP7689079B2 (ja) | 2019-03-28 | 2025-06-05 | オリオニス バイオサイエンシズ，インコーポレイテッド | 治療用インターフェロンアルファ１タンパク質 |
| WO2021037184A1 (zh) * | 2019-08-30 | 2021-03-04 | 正大天晴药业集团南京顺欣制药有限公司 | 一种靶向PD-L1和TGF-β的融合蛋白及其用途 |
| EP4034146A4 (en) * | 2019-09-26 | 2024-03-06 | Orionis Biosciences, Inc. | CONJUGATED CHIMERIC PROTEINS |
| US20220409684A1 (en) * | 2019-11-18 | 2022-12-29 | The Brigham And Women's Hospital, Inc. | Codon optimized new generation regulatable fusogenic oncolytic herpes simplex virus type 1 virus and methods of use |
| KR20220109436A (ko) | 2019-12-03 | 2022-08-04 | 에보텍 인터내셔널 게엠베하 | 인터페론-결합된 항원 결합 단백질 및 이의 용도 |
| CN113354738B (zh) * | 2020-03-05 | 2022-09-09 | 绍兴德方华生物技术有限公司 | 融合毒素VEGF165b/mGEL及其编码基因与应用 |
| CN116234572A (zh) * | 2020-04-30 | 2023-06-06 | 安驰肿瘤公司 | 治疗性SIRPα抗体 |
| WO2022002153A1 (zh) * | 2020-06-30 | 2022-01-06 | 正大天晴药业集团股份有限公司 | 用于治疗肿瘤的药物 |
| WO2022047220A1 (en) * | 2020-08-27 | 2022-03-03 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Oncolytic viruses encoding recombinant tranforming growth factor (tgf)-beta monomers and uses thereof |
| JP2023541601A (ja) | 2020-09-10 | 2023-10-03 | プレシリックス・ナームローゼ・ベンノートシヤープ | Ｆａｐに対する抗体フラグメント |
| WO2022120286A1 (en) * | 2020-12-06 | 2022-06-09 | ALX Oncology Inc. | Multimers for reducing the interference of drugs that bind cd47 in serological assays |
| CN114349850A (zh) * | 2020-12-18 | 2022-04-15 | 蒋庆华 | 抗体及其制备方法和编码核酸以及工程细胞 |
| WO2023203135A1 (en) | 2022-04-22 | 2023-10-26 | Precirix N.V. | Improved radiolabelled antibody |
| CA3251753A1 (en) | 2022-05-02 | 2023-11-09 | Precirix N.V. | PRE-TARGETTING |
| EP4619435A1 (en) | 2022-11-16 | 2025-09-24 | Boehringer Ingelheim International GmbH | Predictive efficacy biomarkers for anti-sirpa antibodies |
| CN116732012A (zh) * | 2023-03-13 | 2023-09-12 | 山东舜丰生物科技有限公司 | 碱基编辑器及其应用 |
| EP4480501A1 (en) * | 2023-06-21 | 2024-12-25 | Nmi Naturwissenschaftliches Und Medizinisches Institut An Der Universität Tübingen | Sirp nanobodies |
| KR20260049221A (ko) * | 2023-07-29 | 2026-04-13 | 상하이 카이진 바이오테크놀로지, 리미티드 | 변형된 e형 다중특이성 항체 |
| CN117430716B (zh) * | 2023-10-16 | 2024-05-31 | 珠海臻谱基因科技有限公司 | 靶向保守的HIV gp41亚基近膜端外区的重组干扰素药物及其应用 |
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- 2018-02-05 IL IL268346A patent/IL268346B2/en unknown
- 2018-02-05 WO PCT/EP2018/052814 patent/WO2018141964A1/en not_active Ceased
- 2018-02-05 KR KR1020197024342A patent/KR102642385B1/ko active Active
- 2018-02-05 AU AU2018216032A patent/AU2018216032B2/en active Active
- 2018-02-05 CA CA3052523A patent/CA3052523A1/en active Pending
- 2018-02-05 US US16/483,114 patent/US11384154B2/en active Active
- 2018-02-05 CN CN201880023712.1A patent/CN110546160A/zh active Pending
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