JP2020530298A5 - - Google Patents
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- JP2020530298A5 JP2020530298A5 JP2020507585A JP2020507585A JP2020530298A5 JP 2020530298 A5 JP2020530298 A5 JP 2020530298A5 JP 2020507585 A JP2020507585 A JP 2020507585A JP 2020507585 A JP2020507585 A JP 2020507585A JP 2020530298 A5 JP2020530298 A5 JP 2020530298A5
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- cancer
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762542921P | 2017-08-09 | 2017-08-09 | |
| US62/542,921 | 2017-08-09 | ||
| PCT/US2018/045743 WO2019032663A1 (en) | 2017-08-09 | 2018-08-08 | PD-1 AND PD-L1 BINDING AGENTS |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020530298A JP2020530298A (ja) | 2020-10-22 |
| JP2020530298A5 true JP2020530298A5 (https=) | 2021-09-16 |
| JP7423511B2 JP7423511B2 (ja) | 2024-01-29 |
Family
ID=65271869
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020507585A Active JP7423511B2 (ja) | 2017-08-09 | 2018-08-08 | Ｐｄ－１およびｐｄ－ｌ１結合物質 |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US11498966B2 (https=) |
| EP (1) | EP3664829A4 (https=) |
| JP (1) | JP7423511B2 (https=) |
| CN (2) | CN111328286B (https=) |
| CA (1) | CA3069994A1 (https=) |
| WO (1) | WO2019032663A1 (https=) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
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| EP3455245A2 (en) * | 2016-05-13 | 2019-03-20 | Orionis Biosciences NV | Therapeutic targeting of non-cellular structures |
| EP3596108A4 (en) | 2017-03-15 | 2020-12-23 | Pandion Operations, Inc. | TARGETED IMMUNOTOLERANCE |
| US10676516B2 (en) | 2017-05-24 | 2020-06-09 | Pandion Therapeutics, Inc. | Targeted immunotolerance |
| US10174092B1 (en) | 2017-12-06 | 2019-01-08 | Pandion Therapeutics, Inc. | IL-2 muteins |
| US10946068B2 (en) | 2017-12-06 | 2021-03-16 | Pandion Operations, Inc. | IL-2 muteins and uses thereof |
| USRE50550E1 (en) | 2017-12-06 | 2025-08-26 | Pandion Operations, Inc. | IL-2 muteins and uses thereof |
| KR102877915B1 (ko) | 2018-02-05 | 2025-10-29 | 오리오니스 바이오사이언시즈 인코포레이티드 | 섬유아세포 결합제 및 이의 용도 |
| GB2593632B (en) * | 2018-10-29 | 2023-05-24 | Umc Utrecht Holding Bv | IGA mediated killing of aberrant cells by CD47-Sirpalpha checkpoint inhibition of neutrophils |
| US12410225B2 (en) | 2018-11-08 | 2025-09-09 | Orionis Biosciences, Inc | Modulation of dendritic cell lineages |
| US12351614B2 (en) | 2019-03-28 | 2025-07-08 | Orionis Biosciences, Inc. | CLEC9A-based chimeric protein complexes |
| JP7773372B2 (ja) | 2019-03-28 | 2025-11-19 | オリオニス バイオサイエンシズ，インコーポレイテッド | 線維芽細胞活性化タンパク質結合物質およびその使用 |
| US11440943B2 (en) | 2019-03-28 | 2022-09-13 | Orionis Biosciences, Inc. | Therapeutic interferon alpha 1 proteins |
| JP7725066B2 (ja) * | 2019-04-18 | 2025-08-19 | キューエルエスエフ バイオセラピューティック インコーポレイテッド | ヒト化抗ｐｄ－ｌ１抗体 |
| BR112021023345A2 (pt) | 2019-05-20 | 2022-02-01 | Pandion Operations Inc | Imunotolerância com alvo em madcam |
| CN112142842B (zh) | 2019-06-27 | 2023-09-01 | 启愈生物技术(上海)有限公司 | 抗PD-L1纳米抗体及其Fc融合蛋白和应用 |
| WO2021062184A1 (en) * | 2019-09-26 | 2021-04-01 | Orionis Biosciences, Inc. | Pd-l1 targeted chimeric proteins and uses thereof |
| US20220378925A1 (en) * | 2019-09-26 | 2022-12-01 | Orionis Biosciences, Inc. | Conjugated chimeric proteins |
| WO2021083335A1 (zh) * | 2019-10-30 | 2021-05-06 | 三优生物医药(上海)有限公司 | Pd-l1结合分子 |
| US20230242655A1 (en) | 2019-12-03 | 2023-08-03 | Evotec International Gmbh | Interferon-associated antigen binding proteins and uses thereof |
| BR112022010824A2 (pt) * | 2019-12-11 | 2022-08-23 | Wuxi Biologics Ireland Ltd | Anticorpo bifuncional contra pd-l1 e tgf¿ |
| EP4107187A4 (en) | 2020-02-21 | 2024-07-03 | Pandion Operations, Inc. | TISSUE-TARGETED IMMUNOTOLERANCE WITH A CD39 EFFECTOR |
| JP2023541601A (ja) | 2020-09-10 | 2023-10-03 | プレシリックス・ナームローゼ・ベンノートシヤープ | Ｆａｐに対する抗体フラグメント |
| IL303149A (en) * | 2020-11-30 | 2023-07-01 | Fred Hutchinson Cancer Center | Pd-l1 binding peptides and peptide complexes and methods of use thereof |
| BR112023016706A2 (pt) * | 2021-02-19 | 2023-10-31 | Seoul Nat Univ R&Db Foundation | Anticorpo ou um fragmento de ligação ao antígeno do mesmo, molécula de ácido nucleico, métodos para produzir um anticorpo ou um fragmento de ligação ao antígeno do mesmo e para detectar agrupamento de diferenciação 47 ou determinar uma quantidade de agrupamento de diferenciação 47 em uma amostra, e, uso do anticorpo ou de um fragmento de ligação ao antígeno do mesmo |
| TWI833227B (zh) * | 2021-05-28 | 2024-02-21 | 大陸商和鉑醫藥（上海）有限責任公司 | 靶向pd-l1和cd73的特異性結合蛋白及其應用 |
| WO2023203135A1 (en) | 2022-04-22 | 2023-10-26 | Precirix N.V. | Improved radiolabelled antibody |
| AU2023264245A1 (en) | 2022-05-02 | 2024-12-19 | Precirix N.V. | Pre-targeting |
| EP4412636A4 (en) * | 2022-06-01 | 2025-09-17 | Remd Biotherapeutics Inc | NOVEL INTERFERON VARIANTS AND BIFUNCTIONAL FUSION MOLECULES THEREOF |
| CN117736323A (zh) * | 2022-09-21 | 2024-03-22 | 三优生物医药(上海)有限公司 | 抗pd-l1抗体及其用途 |
| WO2024137442A1 (en) | 2022-12-21 | 2024-06-27 | Gilead Sciences, Inc. | Combination therapy for treating cancer |
| CN120603849A (zh) * | 2023-01-18 | 2025-09-05 | 科望(苏州)生物医药科技有限公司 | 抗pdl1单域抗体、融合蛋白及其用途 |
| US12459994B2 (en) | 2024-04-12 | 2025-11-04 | Paragon Therapeutics, Inc. | Albumin binding proteins and methods of use |
| WO2025217579A1 (en) * | 2024-04-12 | 2025-10-16 | Paragon Therapeutics, Inc. | Anti-hsa vhh antibodies and compositions thereof |
| WO2026015864A1 (en) * | 2024-07-12 | 2026-01-15 | Outpace Bio, Inc. | Cd8 binding polypeptides and methods of use |
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| DE69007975T2 (de) | 1989-08-22 | 1994-07-21 | Immunex Corp | Fusionsprotein bestehend aus gm-csf und il-3. |
| US6277969B1 (en) | 1991-03-18 | 2001-08-21 | New York University | Anti-TNF antibodies and peptides of human tumor necrosis factor |
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| BR112016001128A2 (pt) | 2013-07-19 | 2018-01-23 | Vib Vzw | membros da família il-1 modificados direcionados |
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| UA119352C2 (uk) | 2014-05-01 | 2019-06-10 | Тева Фармасьютикалз Острейліа Пті Лтд | Комбінація леналідоміду або помалідоміду і конструкції анти-cd38 антитіло-атенуйований інтерферон альфа-2b та спосіб лікування суб'єкта, який має cd38-експресуючу пухлину |
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| WO2018146074A1 (en) | 2017-02-07 | 2018-08-16 | Vib Vzw | Immune-cell targeted bispecific chimeric proteins and uses thereof |
-
2018
- 2018-08-08 EP EP18844220.6A patent/EP3664829A4/en active Pending
- 2018-08-08 US US16/636,501 patent/US11498966B2/en active Active
- 2018-08-08 WO PCT/US2018/045743 patent/WO2019032663A1/en not_active Ceased
- 2018-08-08 CA CA3069994A patent/CA3069994A1/en active Pending
- 2018-08-08 CN CN201880065727.4A patent/CN111328286B/zh active Active
- 2018-08-08 JP JP2020507585A patent/JP7423511B2/ja active Active
- 2018-08-08 CN CN202411067631.5A patent/CN119285770A/zh active Pending
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2022
- 2022-10-05 US US17/938,109 patent/US12351633B2/en active Active
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2025
- 2025-06-03 US US19/226,780 patent/US20250361305A1/en active Pending
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