JP2020504723A5 - - Google Patents

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JP2020504723A5
JP2020504723A5 JP2019533085A JP2019533085A JP2020504723A5 JP 2020504723 A5 JP2020504723 A5 JP 2020504723A5 JP 2019533085 A JP2019533085 A JP 2019533085A JP 2019533085 A JP2019533085 A JP 2019533085A JP 2020504723 A5 JP2020504723 A5 JP 2020504723A5
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seq
amino acid
acid sequence
cdr
variable region
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JP7247091B2 (ja
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JP2019533085A 2016-12-20 2017-12-18 抗cd20/抗cd3二重特異性抗体と4-1bb(cd137)アゴニストの併用療法 Active JP7247091B2 (ja)

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Application Number Priority Date Filing Date Title
EP16205493 2016-12-20
EP16205493.6 2016-12-20
PCT/EP2017/083222 WO2018114748A1 (en) 2016-12-20 2017-12-18 Combination therapy of anti-cd20/anti-cd3 bispecific antibodies and 4-1bb (cd137) agonists

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JP2020504723A JP2020504723A (ja) 2020-02-13
JP2020504723A5 true JP2020504723A5 (https=) 2021-02-04
JP7247091B2 JP7247091B2 (ja) 2023-03-28

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JP2019533085A Active JP7247091B2 (ja) 2016-12-20 2017-12-18 抗cd20/抗cd3二重特異性抗体と4-1bb(cd137)アゴニストの併用療法

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US (2) US11718680B2 (https=)
EP (1) EP3559034B1 (https=)
JP (1) JP7247091B2 (https=)
KR (1) KR102692708B1 (https=)
CN (1) CN110088135A (https=)
AU (1) AU2017384126B2 (https=)
BR (1) BR112019007267A2 (https=)
CA (1) CA3039446A1 (https=)
ES (1) ES2847973T3 (https=)
IL (1) IL267406B2 (https=)
MX (1) MX2019006954A (https=)
PL (1) PL3559034T3 (https=)
TW (1) TWI773712B (https=)
WO (1) WO2018114748A1 (https=)

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BR112020007630A2 (pt) 2017-11-01 2020-11-17 F. Hoffmann-La Roche Ag anticorpo biespecífico ox40, produto farmacêutico, composição farmacêutica e anticorpos biespecíficos anti-fap/ anti-ox40
JP2021500902A (ja) 2017-11-01 2021-01-14 エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト 新規tnfファミリーリガンド三量体含有抗原結合分子
MY205342A (en) 2017-11-01 2024-10-16 Hoffmann La Roche Bispecific 2+1 contorsbodies
TWI841551B (zh) 2018-03-13 2024-05-11 瑞士商赫孚孟拉羅股份公司 使用靶向4-1bb (cd137)之促效劑的組合療法
EP3765489B1 (en) 2018-03-13 2024-10-16 F. Hoffmann-La Roche AG Therapeutic combination of 4-1bb agonists with anti-cd20 antibodies
SG11202007961QA (en) 2018-04-13 2020-09-29 Hoffmann La Roche Her2-targeting antigen binding molecules comprising 4-1bbl
WO2020007817A1 (en) 2018-07-04 2020-01-09 F. Hoffmann-La Roche Ag Novel bispecific agonistic 4-1bb antigen binding molecules
WO2020070041A1 (en) 2018-10-01 2020-04-09 F. Hoffmann-La Roche Ag Bispecific antigen binding molecules comprising anti-fap clone 212
CN112654641A (zh) 2018-10-01 2021-04-13 豪夫迈·罗氏有限公司 具有与cd40的三价结合的双特异性抗原结合分子
UA128001C2 (uk) 2018-12-21 2024-03-06 Ф. Хоффманн-Ля Рош Аг Націлені на пухлину агоністичні cd28-антигензв'язувальні молекули
JP7301155B2 (ja) 2019-04-12 2023-06-30 エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト リポカリンムテインを含む二重特異性抗原結合分子
KR20220025848A (ko) 2019-06-26 2022-03-03 에프. 호프만-라 로슈 아게 Cea 및 4-1bbl에 결합하는 항체의 융합
CN114929734A (zh) 2020-01-09 2022-08-19 豪夫迈·罗氏有限公司 新型含有4-1bbl三聚体的抗原结合分子
AR121706A1 (es) 2020-04-01 2022-06-29 Hoffmann La Roche Moléculas de unión a antígeno biespecíficas dirigidas a ox40 y fap

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