|
CH445129A
(fr)
|
1964-04-29 |
1967-10-15 |
Nestle Sa |
Procédé pour la préparation de composés d'inclusion à poids moléculaire élevé
|
|
US3459731A
(en)
|
1966-12-16 |
1969-08-05 |
Corn Products Co |
Cyclodextrin polyethers and their production
|
|
US3453257A
(en)
|
1967-02-13 |
1969-07-01 |
Corn Products Co |
Cyclodextrin with cationic properties
|
|
US3426011A
(en)
|
1967-02-13 |
1969-02-04 |
Corn Products Co |
Cyclodextrins with anionic properties
|
|
US3453259A
(en)
|
1967-03-22 |
1969-07-01 |
Corn Products Co |
Cyclodextrin polyol ethers and their oxidation products
|
|
US4235871A
(en)
|
1978-02-24 |
1980-11-25 |
Papahadjopoulos Demetrios P |
Method of encapsulating biologically active materials in lipid vesicles
|
|
US5521063A
(en)
|
1985-03-15 |
1996-05-28 |
Antivirals Inc. |
Polynucleotide reagent containing chiral subunits and methods of use
|
|
WO1986005519A1
(en)
|
1985-03-15 |
1986-09-25 |
James Summerton |
Polynucleotide assay reagent and method
|
|
US5506337A
(en)
|
1985-03-15 |
1996-04-09 |
Antivirals Inc. |
Morpholino-subunit combinatorial library and method
|
|
US5034506A
(en)
|
1985-03-15 |
1991-07-23 |
Anti-Gene Development Group |
Uncharged morpholino-based polymers having achiral intersubunit linkages
|
|
US5217866A
(en)
|
1985-03-15 |
1993-06-08 |
Anti-Gene Development Group |
Polynucleotide assay reagent and method
|
|
US5166315A
(en)
|
1989-12-20 |
1992-11-24 |
Anti-Gene Development Group |
Sequence-specific binding polymers for duplex nucleic acids
|
|
US4737323A
(en)
|
1986-02-13 |
1988-04-12 |
Liposome Technology, Inc. |
Liposome extrusion method
|
|
US5525465A
(en)
|
1987-10-28 |
1996-06-11 |
Howard Florey Institute Of Experimental Physiology And Medicine |
Oligonucleotide-polyamide conjugates and methods of production and applications of the same
|
|
US5087617A
(en)
|
1989-02-15 |
1992-02-11 |
Board Of Regents, The University Of Texas System |
Methods and compositions for treatment of cancer using oligonucleotides
|
|
US5670617A
(en)
|
1989-12-21 |
1997-09-23 |
Biogen Inc |
Nucleic acid conjugates of tat-derived transport polypeptides
|
|
KR0166088B1
(ko)
|
1990-01-23 |
1999-01-15 |
. |
수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도
|
|
US5539082A
(en)
|
1993-04-26 |
1996-07-23 |
Nielsen; Peter E. |
Peptide nucleic acids
|
|
US5714331A
(en)
|
1991-05-24 |
1998-02-03 |
Buchardt, Deceased; Ole |
Peptide nucleic acids having enhanced binding affinity, sequence specificity and solubility
|
|
US5719262A
(en)
|
1993-11-22 |
1998-02-17 |
Buchardt, Deceased; Ole |
Peptide nucleic acids having amino acid side chains
|
|
GB9209032D0
(en)
|
1992-04-25 |
1992-06-10 |
Ciba Geigy Ag |
New peptide derivatives
|
|
EP0786522A2
(en)
|
1992-07-17 |
1997-07-30 |
Ribozyme Pharmaceuticals, Inc. |
Enzymatic RNA molecules for treatment of stenotic conditions
|
|
ES2123062T3
(es)
|
1992-08-21 |
1999-01-01 |
Biogen Inc |
Polipeptidos de transporte derivados de la proteina tat.
|
|
DE69429087T2
(de)
|
1993-01-07 |
2002-07-11 |
Thomas Jefferson University, Philadelphia |
Modulation der proliferation von glatten muskelzellen durch antisense inhibition von c-myc
|
|
DE69435005T2
(de)
|
1993-05-11 |
2008-04-17 |
The University Of North Carolina At Chapel Hill |
Antisense Oligonukleotide die anomales Splicing verhindern und deren Verwendung
|
|
US5820873A
(en)
|
1994-09-30 |
1998-10-13 |
The University Of British Columbia |
Polyethylene glycol modified ceramide lipids and liposome uses thereof
|
|
US5753613A
(en)
|
1994-09-30 |
1998-05-19 |
Inex Pharmaceuticals Corporation |
Compositions for the introduction of polyanionic materials into cells
|
|
US5885613A
(en)
|
1994-09-30 |
1999-03-23 |
The University Of British Columbia |
Bilayer stabilizing components and their use in forming programmable fusogenic liposomes
|
|
IL115849A0
(en)
|
1994-11-03 |
1996-01-31 |
Merz & Co Gmbh & Co |
Tangential filtration preparation of liposomal drugs and liposome product thereof
|
|
US5849727A
(en)
|
1996-06-28 |
1998-12-15 |
Board Of Regents Of The University Of Nebraska |
Compositions and methods for altering the biodistribution of biological agents
|
|
CN1263473A
(zh)
|
1997-05-21 |
2000-08-16 |
利兰·斯坦福青年大学托管委员会 |
增加跨生物膜转运的组合物和方法
|
|
US6329501B1
(en)
|
1997-05-29 |
2001-12-11 |
Auburn University |
Methods and compositions for targeting compounds to muscle
|
|
US7572582B2
(en)
|
1997-09-12 |
2009-08-11 |
Exiqon A/S |
Oligonucleotide analogues
|
|
US6794499B2
(en)
|
1997-09-12 |
2004-09-21 |
Exiqon A/S |
Oligonucleotide analogues
|
|
WO1999042091A2
(en)
|
1998-02-19 |
1999-08-26 |
Massachusetts Institute Of Technology |
Use of polycations as endosomolytic agents
|
|
US6683173B2
(en)
|
1998-04-03 |
2004-01-27 |
Epoch Biosciences, Inc. |
Tm leveling methods
|
|
AU5583799A
(en)
|
1998-08-25 |
2000-03-14 |
Human Genome Sciences, Inc. |
49 human secreted proteins
|
|
US6210892B1
(en)
|
1998-10-07 |
2001-04-03 |
Isis Pharmaceuticals, Inc. |
Alteration of cellular behavior by antisense modulation of mRNA processing
|
|
JP2000125448A
(ja)
|
1998-10-14 |
2000-04-28 |
Yazaki Corp |
電気接続箱
|
|
KR20010102992A
(ko)
|
1999-01-29 |
2001-11-17 |
추후보정 |
표적 ｒｎａ를 검출하는 비-침입적 방법
|
|
JP2000256547A
(ja)
|
1999-03-10 |
2000-09-19 |
Sumitomo Dow Ltd |
耐熱性プラスチックカード用樹脂組成物
|
|
US7084125B2
(en)
|
1999-03-18 |
2006-08-01 |
Exiqon A/S |
Xylo-LNA analogues
|
|
CA2365984A1
(en)
|
1999-04-08 |
2000-10-19 |
Oasis Biosciences, Inc. |
Antisense oligonucleotides comprising universal and/or degenerate bases
|
|
US7053207B2
(en)
|
1999-05-04 |
2006-05-30 |
Exiqon A/S |
L-ribo-LNA analogues
|
|
JP2000325085A
(ja)
|
1999-05-21 |
2000-11-28 |
Masafumi Matsuo |
デュシェンヌ型筋ジストロフィー治療剤
|
|
DE60039601D1
(de)
|
1999-05-24 |
2008-09-04 |
Avi Biopharma Inc |
Antisense gegen c-myc zur behandlung von polyzystischer nierenkrankheit
|
|
US6303573B1
(en)
|
1999-06-07 |
2001-10-16 |
The Burnham Institute |
Heart homing peptides and methods of using same
|
|
US6593292B1
(en)
|
1999-08-24 |
2003-07-15 |
Cellgate, Inc. |
Compositions and methods for enhancing drug delivery across and into epithelial tissues
|
|
US7229961B2
(en)
|
1999-08-24 |
2007-06-12 |
Cellgate, Inc. |
Compositions and methods for enhancing drug delivery across and into ocular tissues
|
|
US6669951B2
(en)
|
1999-08-24 |
2003-12-30 |
Cellgate, Inc. |
Compositions and methods for enhancing drug delivery across and into epithelial tissues
|
|
US20030104622A1
(en)
|
1999-09-01 |
2003-06-05 |
Robbins Paul D. |
Identification of peptides that facilitate uptake and cytoplasmic and/or nuclear transport of proteins, DNA and viruses
|
|
WO2001047496A1
(en)
|
1999-12-29 |
2001-07-05 |
Mixson A James |
Histidine copolymer and methods for using same
|
|
US7070807B2
(en)
|
1999-12-29 |
2006-07-04 |
Mixson A James |
Branched histidine copolymers and methods for using same
|
|
US20020009491A1
(en)
|
2000-02-14 |
2002-01-24 |
Rothbard Jonathan B. |
Compositions and methods for enhancing drug delivery across biological membranes and tissues
|
|
US6653467B1
(en)
|
2000-04-26 |
2003-11-25 |
Jcr Pharmaceutical Co., Ltd. |
Medicament for treatment of Duchenne muscular dystrophy
|
|
US6727355B2
(en)
|
2000-08-25 |
2004-04-27 |
Jcr Pharmaceuticals Co., Ltd. |
Pharmaceutical composition for treatment of Duchenne muscular dystrophy
|
|
US6559279B1
(en)
|
2000-09-08 |
2003-05-06 |
Isis Pharmaceuticals, Inc. |
Process for preparing peptide derivatized oligomeric compounds
|
|
US20040170955A1
(en)
|
2000-09-08 |
2004-09-02 |
Wadih Arap |
Human and mouse targeting peptides identified by phage display
|
|
EP1191097A1
(en)
|
2000-09-21 |
2002-03-27 |
Leids Universitair Medisch Centrum |
Induction of exon skipping in eukaryotic cells
|
|
WO2002038764A2
(en)
|
2000-11-10 |
2002-05-16 |
The Regents Of The University Of California |
Il-17 receptor-like protein, uses thereof, and modulation of catabolic activity of il-17 cytokines on bone and cartilage
|
|
WO2002063280A1
(en)
|
2001-02-06 |
2002-08-15 |
Auburn University |
Ligand sensor devices and uses thereof
|
|
AU2002250034A1
(en)
|
2001-02-08 |
2002-08-19 |
Sequitur, Inc. |
Methods of light activated release 0f ligands from endosomes
|
|
DE60233137D1
(de)
|
2001-02-16 |
2009-09-10 |
Univ R |
Transporter mit beabstandeten arginin-teilchen
|
|
US7456146B2
(en)
|
2001-05-09 |
2008-11-25 |
Ghc Research Development Corporation |
Lytic peptide prodrugs
|
|
NZ530101A
(en)
|
2001-05-17 |
2007-01-26 |
Avi Biopharma Inc |
Methods for treating cancer by administering an oligomer antisense to c-myc together with a cancer chemotherapeutic agent
|
|
JP3735292B2
(ja)
|
2001-07-26 |
2006-01-18 |
三菱重工業株式会社 |
ダイエット効果のある健康食品および製剤
|
|
US6645974B2
(en)
|
2001-07-31 |
2003-11-11 |
Merck & Co., Inc. |
Androgen receptor modulators and methods for use thereof
|
|
US20090075377A1
(en)
|
2001-08-03 |
2009-03-19 |
Arbor Vita Corporation |
Molecular interactions in cells
|
|
CA2459347C
(en)
|
2001-09-04 |
2012-10-09 |
Exiqon A/S |
Locked nucleic acid (lna) compositions and uses thereof
|
|
WO2003049772A2
(en)
|
2001-12-11 |
2003-06-19 |
The Board Of Trustees Of The Leland Stanford Junior University |
Guanidinium transport reagents and conjugates
|
|
KR100464261B1
(ko)
|
2002-01-24 |
2005-01-03 |
주식회사 파나진 |
Ｐｎａ 올리고머를 합성하기 위한 신규한 단량체 및 그의제조방법
|
|
KR20030084444A
(ko)
|
2002-04-26 |
2003-11-01 |
주식회사 파나진 |
Ｐｎａ 올리고머를 합성하기 위한 신규한 단량체 및 그의제조방법
|
|
US7569575B2
(en)
|
2002-05-08 |
2009-08-04 |
Santaris Pharma A/S |
Synthesis of locked nucleic acid derivatives
|
|
AU2003287464A1
(en)
|
2002-11-05 |
2004-06-03 |
Isis Pharmaceuticals, Inc. |
2'-fluoro substituted oligomeric compounds and compositions for use in gene modulations
|
|
EP2392660A3
(en)
|
2002-11-25 |
2012-03-28 |
Masafumi Matsuo |
ENA Nucleic Acid Drugs Modifying Splicing in mRNA Precursor
|
|
WO2004084805A2
(en)
|
2003-03-19 |
2004-10-07 |
The J. David Gladstone Institutes |
Acetylated tat polypeptides and methods of use thereof
|
|
AU2003225410A1
(en)
|
2003-03-21 |
2004-10-11 |
Academisch Ziekenhuis Leiden |
Modulation of exon recognition in pre-mrna by interfering with the secondary rna structure
|
|
US7468418B2
(en)
|
2003-04-29 |
2008-12-23 |
Avi Biopharma., Inc. |
Compositions for enhancing transport of molecules into cells
|
|
EP2784084B2
(en)
|
2003-07-08 |
2023-10-04 |
Novartis Pharma AG |
Antagonist antibodies to IL-17A/F heterologous polypeptides
|
|
US7211668B2
(en)
|
2003-07-28 |
2007-05-01 |
Panagene, Inc. |
PNA monomer and precursor
|
|
US20050203041A1
(en)
|
2003-09-23 |
2005-09-15 |
Mourich Dan V. |
Antisense compound and method for selectively killing activated T cells
|
|
US20050222068A1
(en)
|
2003-10-23 |
2005-10-06 |
Mourich Dan V |
Method and antisense composition for selective inhibition of HIV infection in hematopoietic cells
|
|
US7786151B2
(en)
|
2004-01-09 |
2010-08-31 |
Kinopharma, Inc. |
Therapeutic composition of treating abnormal splicing caused by the excessive kinase induction
|
|
CA2553104A1
(en)
|
2004-01-23 |
2005-08-11 |
Avi Biopharma, Inc. |
Antisense oligomers and methods for inducing immune tolerance and immunosuppression
|
|
WO2005077333A2
(en)
|
2004-02-10 |
2005-08-25 |
University Of Florida Research Foundation, Inc. |
Gel-based delivery of recombinant adeno-associated virus vectors
|
|
US7402574B2
(en)
|
2004-03-12 |
2008-07-22 |
Avi Biopharma, Inc. |
Antisense composition and method for treating cancer
|
|
US20050288246A1
(en)
|
2004-05-24 |
2005-12-29 |
Iversen Patrick L |
Peptide conjugated, inosine-substituted antisense oligomer compound and method
|
|
US20060014712A1
(en)
|
2004-05-30 |
2006-01-19 |
Cemines, Inc. |
Controlled delivery of therapeutic compounds
|
|
EP2933332A1
(en)
|
2004-06-28 |
2015-10-21 |
The University Of Western Australia |
Antisense oligonucleotides for inducing exon skipping and methods of use thereof
|
|
EP1789553B1
(en)
|
2004-06-30 |
2014-03-26 |
Alnylam Pharmaceuticals Inc. |
Oligonucleotides comprising a non-phosphate backbone linkage
|
|
US7947645B2
(en)
|
2004-09-02 |
2011-05-24 |
Cognosci, Inc. |
APO E analogs and methods for their use
|
|
WO2006031996A2
(en)
|
2004-09-14 |
2006-03-23 |
University Of Pittsburgh Of The Commonwealth System Of Higher Education |
Targeting viruses using a modified sindbis glycoprotein
|
|
US8129352B2
(en)
|
2004-09-16 |
2012-03-06 |
Avi Biopharma, Inc. |
Antisense antiviral compound and method for treating ssRNA viral infection
|
|
US8357664B2
(en)
|
2004-10-26 |
2013-01-22 |
Avi Biopharma, Inc. |
Antisense antiviral compound and method for treating influenza viral infection
|
|
US7524829B2
(en)
|
2004-11-01 |
2009-04-28 |
Avi Biopharma, Inc. |
Antisense antiviral compounds and methods for treating a filovirus infection
|
|
NZ538097A
(en)
|
2005-02-07 |
2006-07-28 |
Ovita Ltd |
Method and compositions for improving wound healing
|
|
EP1855694B1
(en)
|
2005-02-09 |
2020-12-02 |
Sarepta Therapeutics, Inc. |
Antisense composition for treating muscle atrophy
|
|
GT200600065A
(es)
|
2005-02-14 |
2006-10-02 |
|
Anticuerpos para interleucina-17f y otros antagonistas de la señalizacion de il-17f y sus usos
|
|
WO2006112705A2
(en)
|
2005-04-22 |
2006-10-26 |
Academisch Ziekenhuis Leiden |
Modulation of exon recognition in pre-mrna by interfering with the binding of sr proteins and by interfering with secondary rna structure.
|
|
WO2006114478A1
(en)
|
2005-04-26 |
2006-11-02 |
Karyon-Ctt Ltd |
Diagnostic and therapeutic agents
|
|
US8067571B2
(en)
|
2005-07-13 |
2011-11-29 |
Avi Biopharma, Inc. |
Antibacterial antisense oligonucleotide and method
|
|
US7790694B2
(en)
|
2005-07-13 |
2010-09-07 |
Avi Biopharma Inc. |
Antisense antibacterial method and compound
|
|
WO2007009094A2
(en)
|
2005-07-13 |
2007-01-18 |
Avi Biopharma, Inc. |
Antisense antibacterial method and compound
|
|
WO2007030576A2
(en)
|
2005-09-08 |
2007-03-15 |
Avi Biopharma, Inc. |
Antisense antiviral compound and method for treating picornavirus infection
|
|
US8524676B2
(en)
|
2005-09-08 |
2013-09-03 |
Sarepta Therapeutics, Inc. |
Method for treating enterovirus or rhinovirus infection using antisense antiviral compounds
|
|
EP1941275B1
(en)
|
2005-09-29 |
2013-07-24 |
Medimmune, Inc. |
Method of identifying membrane lg specific antibodies and use thereof for targeting immunoglobulin-producing precursor cells
|
|
US20070111962A1
(en)
|
2005-11-08 |
2007-05-17 |
Mourich Dan V |
Immunosuppression compound and treatment method
|
|
US8501704B2
(en)
|
2005-11-08 |
2013-08-06 |
Sarepta Therapeutics, Inc. |
Immunosuppression compound and treatment method
|
|
WO2007058894A2
(en)
|
2005-11-10 |
2007-05-24 |
The University Of North Carolina At Chapel Hill |
Splice switching oligomers for tnf superfamily receptors and their use in treatment of disease
|
|
US7582615B2
(en)
|
2006-03-07 |
2009-09-01 |
Avi Biopharma, Inc. |
Antisense antiviral compound and method for treating arenavirus infection
|
|
US8785407B2
(en)
|
2006-05-10 |
2014-07-22 |
Sarepta Therapeutics, Inc. |
Antisense antiviral agent and method for treating ssRNA viral infection
|
|
PL2735568T3
(pl)
|
2006-05-10 |
2018-02-28 |
Sarepta Therapeutics, Inc. |
Analogi oligonukleotydowe mające kationowe połączenia pomiędzy podjednostkami
|
|
DE212006000097U1
(de)
|
2006-05-17 |
2009-02-26 |
Sokolova, Svetlana Anatolevna |
Transportmittel
|
|
AU2006345724B2
(en)
|
2006-06-30 |
2013-11-21 |
Lakewood-Amedex, Inc. |
Compositions and methods for the treatment of muscle wasting
|
|
SI2049664T1
(sl)
|
2006-08-11 |
2012-04-30 |
Prosensa Technologies Bv |
Enojna veriga oligonukleotidov, komplementarna repetitivnim elementom, za zdravljenje genetskih bolezni, povezanih z nestabilnostjo dnk ponovitev
|
|
US20080199961A1
(en)
|
2006-08-25 |
2008-08-21 |
Avi Biopharma, Inc. |
ANTISENSE COMPOSITION AND METHOD FOR INHIBITION OF miRNA BIOGENESIS
|
|
US20080267978A1
(en)
|
2006-08-28 |
2008-10-30 |
Mary Zutter |
Anti-angiogenic targets for cancer therapy
|
|
EP2560001B1
(en)
|
2006-09-21 |
2016-04-13 |
University of Rochester |
Compositions and methods related to protein displacement therapy for myotonic distrophy
|
|
FR2908999B1
(fr)
|
2006-11-29 |
2012-04-27 |
Biomerieux Sa |
Nouveau medicament destine a l'inhibition, la prevention ou le traitement de la polyarthrite rhumatoide.
|
|
EP1938802A1
(en)
|
2006-12-22 |
2008-07-02 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Interfering RNAs targeting pro-inflammatory cytokines
|
|
US20100016215A1
(en)
|
2007-06-29 |
2010-01-21 |
Avi Biopharma, Inc. |
Compound and method for treating myotonic dystrophy
|
|
WO2009005793A2
(en)
|
2007-06-29 |
2009-01-08 |
Avi Biopharma, Inc. |
Tissue specific peptide conjugates and methods
|
|
CA2693742A1
(en)
|
2007-07-12 |
2009-01-15 |
Prosensa Technologies B.V. |
Molecules for targeting compounds to various selected organs, tissues or tumor cells
|
|
US20110300154A1
(en)
|
2007-08-21 |
2011-12-08 |
Children's Medical Center Corporation |
Treatment of airway hyperreactivity
|
|
ES2639852T3
(es)
|
2007-10-26 |
2017-10-30 |
Academisch Ziekenhuis Leiden |
Medios y métodos para contrarrestar los trastornos musculares
|
|
RU2606627C2
(ru)
|
2007-11-15 |
2017-01-10 |
Серепта Терапьютикс,Инк. |
Способ синтеза морфолиновых олигомеров
|
|
US8299206B2
(en)
|
2007-11-15 |
2012-10-30 |
Avi Biopharma, Inc. |
Method of synthesis of morpholino oligomers
|
|
US8076476B2
(en)
|
2007-11-15 |
2011-12-13 |
Avi Biopharma, Inc. |
Synthesis of morpholino oligomers using doubly protected guanine morpholino subunits
|
|
EP2235034B1
(en)
|
2007-12-28 |
2016-11-23 |
Sarepta Therapeutics, Inc. |
Immunomodulatory agents and methods of use
|
|
WO2009127230A1
(en)
|
2008-04-16 |
2009-10-22 |
Curevac Gmbh |
MODIFIED (m)RNA FOR SUPPRESSING OR AVOIDING AN IMMUNOSTIMULATORY RESPONSE AND IMMUNOSUPPRESSIVE COMPOSITION
|
|
EP2119783A1
(en)
|
2008-05-14 |
2009-11-18 |
Prosensa Technologies B.V. |
Method for efficient exon (44) skipping in Duchenne Muscular Dystrophy and associated means
|
|
WO2009144481A2
(en)
|
2008-05-30 |
2009-12-03 |
Isis Innovation Limited |
Conjugates for delivery of biologically active compounds
|
|
US8084601B2
(en)
|
2008-09-11 |
2011-12-27 |
Royal Holloway And Bedford New College Royal Holloway, University Of London |
Oligomers
|
|
BR122020021379B1
(pt)
|
2008-10-24 |
2021-05-11 |
Sarepta Therapeutics, Inc. |
oligômero morfolino fosforodiamidato, composição que compreende o mesmo e uso do dito oligômero para tratar distrofia muscular
|
|
AU2009310557B2
(en)
|
2008-10-27 |
2014-09-11 |
Academisch Ziekenhuis Leiden |
Methods and means for efficient skipping of exon 45 in Duchenne Muscular Dystrophy pre-mRNA
|
|
CN102282155B
(zh)
|
2008-12-02 |
2017-06-09 |
日本波涛生命科学公司 |
磷原子修饰的核酸的合成方法
|
|
EP2376633A1
(en)
|
2008-12-17 |
2011-10-19 |
AVI BioPharma, Inc. |
Antisense compositions and methods for modulating contact hypersensitivity or contact dermatitis
|
|
CA2758189C
(en)
|
2009-04-10 |
2020-12-29 |
Association Institut De Myologie |
Tricyclo-dna antisense oligonucleotides, compositions, and methods for the treatment of disease
|
|
EP2421971B1
(en)
|
2009-04-24 |
2016-07-06 |
BioMarin Technologies B.V. |
Oligonucleotide comprising an inosine for treating dmd
|
|
US20110269665A1
(en)
|
2009-06-26 |
2011-11-03 |
Avi Biopharma, Inc. |
Compound and method for treating myotonic dystrophy
|
|
RU2612521C2
(ru)
|
2009-07-06 |
2017-03-09 |
Онтории, Инк. |
Новые пролекарства нуклеиновых кислот и способы их применения
|
|
ES2586683T3
(es)
|
2009-09-16 |
2016-10-18 |
Wave Life Sciences Japan, Inc. |
Grupo protector novedoso para sintetizar ARN y derivados del mismo
|
|
TR201816523T4
(tr)
|
2009-11-12 |
2018-11-21 |
Univ Western Australia |
Patolojilerin tedavisine yönelik antisens moleküller ve yöntemler.
|
|
CA3090304A1
(en)
|
2010-05-13 |
2011-11-17 |
Sarepta Therapeutics, Inc. |
Antisense modulation of interleukins 17 and 23 signaling
|
|
KR20200133284A
(ko)
|
2010-05-28 |
2020-11-26 |
사렙타 쎄러퓨틱스, 인코퍼레이티드 |
변형된 서브유니트간 결합 및/또는 말단 그룹을 갖는 올리고뉴클레오타이드 유사체
|
|
TWI541024B
(zh)
|
2010-09-01 |
2016-07-11 |
日本新藥股份有限公司 |
反義核酸
|
|
JP5868324B2
(ja)
|
2010-09-24 |
2016-02-24 |
株式会社Wave Life Sciences Japan |
不斉補助基
|
|
EP2672977A1
(en)
|
2011-02-08 |
2013-12-18 |
The Charlotte-Mecklenburg Hospital Authority d/b/a Carolina Healthcare System |
Antisense oligonucleotides
|
|
US9161948B2
(en)
*
|
2011-05-05 |
2015-10-20 |
Sarepta Therapeutics, Inc. |
Peptide oligonucleotide conjugates
|
|
CA3092114A1
(en)
*
|
2011-05-05 |
2012-11-08 |
Sarepta Therapeutics, Inc. |
Peptide oligonucleotide conjugates
|
|
US9607308B2
(en)
|
2011-06-29 |
2017-03-28 |
American Express Travel Related Services Company, Inc. |
Spend based digital ad targeting and measurement
|
|
PL2581448T3
(pl)
|
2011-10-13 |
2015-08-31 |
Association Inst De Myologie |
Tricyklo-tiofosforanowy DNA
|
|
JP6496549B2
(ja)
|
2011-11-30 |
2019-04-03 |
サレプタ セラピューティクス， インコーポレイテッド |
脊髄性筋萎縮症における誘発されたエクソン包含
|
|
CA2861247C
(en)
|
2011-12-28 |
2021-11-16 |
Nippon Shinyaku Co., Ltd. |
Antisense nucleic acids
|
|
NZ627896A
(en)
|
2012-01-27 |
2016-11-25 |
Biomarin Technologies B V |
Rna modulating oligonucleotides with improved characteristics for the treatment of duchenne and becker muscular dystrophy
|
|
DE102012101676A1
(de)
|
2012-02-29 |
2013-08-29 |
Klaus-Dieter Rösler |
Verfahren und Vorrichtung zum Bearbeiten von Formularen mit einer Datenverarbeitungsanlage
|
|
EP2870246B1
(en)
|
2012-07-03 |
2019-09-11 |
BioMarin Technologies B.V. |
Oligonucleotide for the treatment of muscular dystrophy patients
|
|
PL2872485T3
(pl)
|
2012-07-13 |
2021-05-31 |
Wave Life Sciences Ltd. |
Asymetryczna grupa pomocnicza
|
|
KR102213609B1
(ko)
|
2012-07-13 |
2021-02-08 |
웨이브 라이프 사이언시스 리미티드 |
키랄 제어
|
|
HK1216902A1
(zh)
|
2012-12-20 |
2016-12-09 |
Sarepta Therapeutics, Inc. |
用作治疗肌肉萎缩的改进外显子跳跃组合物
|
|
US20140315977A1
(en)
|
2013-03-14 |
2014-10-23 |
Sarepta Therapeutics, Inc. |
Exon skipping compositions for treating muscular dystrophy
|
|
CN110218727A
(zh)
|
2013-03-14 |
2019-09-10 |
萨勒普塔医疗公司 |
用于治疗肌营养不良的外显子跳跃组合物
|
|
US20140329762A1
(en)
*
|
2013-03-15 |
2014-11-06 |
Sarepta Therapeutics, Inc. |
Compositions for treating muscular dystrophy
|
|
US11236338B2
(en)
*
|
2013-09-05 |
2022-02-01 |
Sarepta Therapeutics, Inc. |
Antisense-induced exon2 inclusion in acid alpha-glucosidase
|
|
JPWO2015108047A1
(ja)
|
2014-01-15 |
2017-03-23 |
株式会社新日本科学 |
免疫誘導活性を有するキラル核酸アジュバンド及び免疫誘導活性剤
|
|
JPWO2015108048A1
(ja)
|
2014-01-15 |
2017-03-23 |
株式会社新日本科学 |
抗腫瘍作用を有するキラル核酸アジュバンド及び抗腫瘍剤
|
|
US10322173B2
(en)
|
2014-01-15 |
2019-06-18 |
Shin Nippon Biomedical Laboratories, Ltd. |
Chiral nucleic acid adjuvant having anti-allergic activity, and anti-allergic agent
|
|
BR112016016400A2
(pt)
|
2014-01-16 |
2017-10-03 |
Wave Life Sciences Ltd |
Composições de oligonucleotídeos quiralmente controlados, seu uso, sua composição farmacêutica, e métodos
|
|
DK3118311T3
(en)
|
2014-03-12 |
2019-03-11 |
Nippon Shinyaku Co Ltd |
Antisense nucleic acid
|
|
MX373052B
(es)
|
2014-06-17 |
2020-05-11 |
Nippon Shinyaku Co Ltd |
Acidos nucleicos antisentido.
|
|
AU2015338923B2
(en)
|
2014-11-02 |
2021-10-21 |
Arcturus Therapeutics, Inc. |
Messenger UNA molecules and uses thereof
|
|
IL320434A
(en)
|
2015-07-22 |
2025-06-01 |
Wave Life Sciences Ltd |
Oligonucleotide preparations and methods
|
|
IL295755A
(en)
|
2015-10-09 |
2022-10-01 |
Wave Life Sciences Ltd |
Oligonucleotide compositions and methods thereof
|
|
EP3858993A1
(en)
|
2015-10-09 |
2021-08-04 |
Sarepta Therapeutics, Inc. |
Compositions and methods for treating duchenne muscular dystrophy and related disorders
|
|
CN109462995A
(zh)
|
2016-05-04 |
2019-03-12 |
波涛生命科学有限公司 |
生物活性剂的方法和组合物
|
|
EP3452596A4
(en)
|
2016-05-04 |
2020-03-18 |
Wave Life Sciences Ltd. |
OLIGONUCLEOTIDE COMPOSITIONS AND RELATED METHODS
|
|
KR102810425B1
(ko)
*
|
2016-12-19 |
2025-05-21 |
사렙타 쎄러퓨틱스 인코퍼레이티드 |
근육 이상증에 대한 엑손 스킵핑 올리고머 결합체
|