JP2021521794A5 - - Google Patents
Info
- Publication number
- JP2021521794A5 JP2021521794A5 JP2020557910A JP2020557910A JP2021521794A5 JP 2021521794 A5 JP2021521794 A5 JP 2021521794A5 JP 2020557910 A JP2020557910 A JP 2020557910A JP 2020557910 A JP2020557910 A JP 2020557910A JP 2021521794 A5 JP2021521794 A5 JP 2021521794A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutically acceptable
- antisense oligomer
- acceptable salt
- exon
- dystrophin
- Prior art date
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023202664A JP2024009344A (ja) | 2018-04-26 | 2023-11-30 | 筋ジストロフィーに対するエクソンスキッピングオリゴマーおよびオリゴマーコンジュゲート |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862663162P | 2018-04-26 | 2018-04-26 | |
| US62/663,162 | 2018-04-26 | ||
| PCT/US2019/028613 WO2019209764A2 (en) | 2018-04-26 | 2019-04-23 | Exon skipping oligomers and oligomer conjugates for muscular dystrophy |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023202664A Division JP2024009344A (ja) | 2018-04-26 | 2023-11-30 | 筋ジストロフィーに対するエクソンスキッピングオリゴマーおよびオリゴマーコンジュゲート |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021521794A JP2021521794A (ja) | 2021-08-30 |
| JP2021521794A5 true JP2021521794A5 (https=) | 2022-04-25 |
| JPWO2019209764A5 JPWO2019209764A5 (https=) | 2022-04-25 |
Family
ID=68295765
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020557910A Pending JP2021521794A (ja) | 2018-04-26 | 2019-04-23 | 筋ジストロフィーに対するエクソンスキッピングオリゴマーおよびオリゴマーコンジュゲート |
| JP2023202664A Pending JP2024009344A (ja) | 2018-04-26 | 2023-11-30 | 筋ジストロフィーに対するエクソンスキッピングオリゴマーおよびオリゴマーコンジュゲート |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023202664A Pending JP2024009344A (ja) | 2018-04-26 | 2023-11-30 | 筋ジストロフィーに対するエクソンスキッピングオリゴマーおよびオリゴマーコンジュゲート |
Country Status (4)
| Country | Link |
|---|---|
| US (2) | US20210102205A1 (https=) |
| EP (1) | EP3784248A4 (https=) |
| JP (2) | JP2021521794A (https=) |
| WO (1) | WO2019209764A2 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11168141B2 (en) | 2018-08-02 | 2021-11-09 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating dystrophinopathies |
| EP3829595A4 (en) | 2018-08-02 | 2022-08-24 | Dyne Therapeutics, Inc. | MUSCLE-DIRECTED COMPLEXES AND USES THEREOF IN THE TREATMENT OF DYSTROPHINOPATHIES |
| US12018087B2 (en) | 2018-08-02 | 2024-06-25 | Dyne Therapeutics, Inc. | Muscle-targeting complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and methods of delivering oligonucleotide to a subject |
| US20220193250A1 (en) | 2018-08-02 | 2022-06-23 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy |
| CA3211038A1 (en) * | 2021-02-12 | 2022-08-18 | Oxford University Innovation Limited | Cell-penetrating peptide conjugates and methods of their use |
| US11771776B2 (en) | 2021-07-09 | 2023-10-03 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating dystrophinopathies |
| US11969475B2 (en) | 2021-07-09 | 2024-04-30 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE498685T1 (de) * | 2004-06-28 | 2011-03-15 | Univ Western Australia | Antisense-oligonukleotide zur induktion von exon- skipping sowie verfahren zur verwendung davon |
| CN112574988A (zh) * | 2008-10-24 | 2021-03-30 | 萨雷普塔治疗公司 | 用于dmd的多外显子跳跃组合物 |
| TWI541024B (zh) * | 2010-09-01 | 2016-07-11 | 日本新藥股份有限公司 | 反義核酸 |
| WO2012150960A1 (en) * | 2011-05-05 | 2012-11-08 | Avi Biopharma, Inc. | Peptide oligonucleotide conjugates |
| CN103998458B (zh) * | 2011-08-30 | 2018-10-09 | 医学研究理事会 | 具有中央疏水域的细胞穿透肽 |
| CA2894899A1 (en) * | 2012-12-20 | 2014-06-26 | Sarepta Therapeutics, Inc. | Improved exon skipping compositions for treating muscular dystrophy |
| RS58529B1 (sr) * | 2013-03-14 | 2019-04-30 | Sarepta Therapeutics Inc | Sastavi koji preskaču egzon za tretiranje mišićne distrofije |
| CA2906812A1 (en) * | 2013-03-15 | 2014-09-18 | Sarepta Therapeutics, Inc. | Improved compositions for treating muscular dystrophy |
| WO2016138534A2 (en) * | 2015-02-27 | 2016-09-01 | Sarepta Therapeutics, Inc. | Antisense-induced exon2 inclusion in acid alpha-glucosidase |
| EP3858993A1 (en) * | 2015-10-09 | 2021-08-04 | Sarepta Therapeutics, Inc. | Compositions and methods for treating duchenne muscular dystrophy and related disorders |
| MA49775A (fr) * | 2016-05-24 | 2020-06-10 | Sarepta Therapeutics Inc | Procédés de préparation d'oligomères morpholino de phosphorodiamidate |
| TW201811807A (zh) * | 2016-06-30 | 2018-04-01 | 美商薩羅塔治療公司 | 用於肌肉萎縮症之外顯子跳躍寡聚物 |
-
2019
- 2019-04-23 EP EP19793325.2A patent/EP3784248A4/en active Pending
- 2019-04-23 JP JP2020557910A patent/JP2021521794A/ja active Pending
- 2019-04-23 US US17/048,163 patent/US20210102205A1/en not_active Abandoned
- 2019-04-23 WO PCT/US2019/028613 patent/WO2019209764A2/en not_active Ceased
-
2023
- 2023-11-30 JP JP2023202664A patent/JP2024009344A/ja active Pending
-
2024
- 2024-04-12 US US18/634,360 patent/US20250092393A1/en active Pending
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