JP2020500929A5 - - Google Patents

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JP2020500929A5
JP2020500929A5 JP2019547592A JP2019547592A JP2020500929A5 JP 2020500929 A5 JP2020500929 A5 JP 2020500929A5 JP 2019547592 A JP2019547592 A JP 2019547592A JP 2019547592 A JP2019547592 A JP 2019547592A JP 2020500929 A5 JP2020500929 A5 JP 2020500929A5
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nucleotides
dsrna agent
double
agent according
dsrna
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JP2019547592A
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JP7348067B2 (ja
JP2020500929A (ja
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JP2019547592A 2016-11-23 2017-11-21 ＳＥＲＰＩＮＡ１ ｉＲＮＡ組成物およびその使用方法 Active JP7348067B2 (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201662425907P 2016-11-23 2016-11-23
US62/425,907 2016-11-23
US201762548589P 2017-08-22 2017-08-22
US62/548,589 2017-08-22
US201762549099P 2017-08-23 2017-08-23
US62/549,099 2017-08-23
US201762561514P 2017-09-21 2017-09-21
US62/561,514 2017-09-21
PCT/US2017/062701 WO2018098117A1 (en) 2016-11-23 2017-11-21 SERPINA1 iRNA COMPOSITIONS AND METHODS OF USE THEREOF

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JP2020500929A JP2020500929A (ja) 2020-01-16
JP2020500929A5 true JP2020500929A5 (enrdf_load_html_response) 2021-01-07
JP7348067B2 JP7348067B2 (ja) 2023-09-20

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US (3) US10995336B2 (enrdf_load_html_response)
EP (1) EP3545093A1 (enrdf_load_html_response)
JP (1) JP7348067B2 (enrdf_load_html_response)
KR (1) KR20190082317A (enrdf_load_html_response)
CN (1) CN110114463B (enrdf_load_html_response)
AU (1) AU2017363604A1 (enrdf_load_html_response)
BR (1) BR112019010342A2 (enrdf_load_html_response)
CA (1) CA3044562A1 (enrdf_load_html_response)
CL (1) CL2019001388A1 (enrdf_load_html_response)
CO (1) CO2019005992A2 (enrdf_load_html_response)
CR (1) CR20190294A (enrdf_load_html_response)
DO (1) DOP2019000132A (enrdf_load_html_response)
IL (1) IL266746A (enrdf_load_html_response)
MA (1) MA46923A (enrdf_load_html_response)
MX (1) MX2019005898A (enrdf_load_html_response)
MY (1) MY199978A (enrdf_load_html_response)
PH (1) PH12019550076A1 (enrdf_load_html_response)
RU (2) RU2761667C2 (enrdf_load_html_response)
SG (1) SG10201913877WA (enrdf_load_html_response)
TW (2) TWI788312B (enrdf_load_html_response)
UY (1) UY37494A (enrdf_load_html_response)
WO (1) WO2018098117A1 (enrdf_load_html_response)
ZA (1) ZA202103080B (enrdf_load_html_response)

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JP2024537251A (ja) * 2021-10-08 2024-10-10 イー－セラピューティクス・ピーエルシー 脱塩基ヌクレオシドを含有する核酸
EP4493570A2 (en) 2022-03-16 2025-01-22 Empirico Inc. Galnac compositions for improving sirna bioavailability
TW202403044A (zh) 2022-03-28 2024-01-16 美商安彼瑞可股份有限公司 經修飾之寡核苷酸
JP2025524135A (ja) * 2022-07-27 2025-07-25 イー－セラピューティクス・ピーエルシー 核酸化合物
CN117070583B (zh) * 2023-10-16 2024-05-14 吉林凯莱英制药有限公司 抑制PCSK9基因表达的siRNA的制备方法
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