JP2020500528A5 - - Google Patents
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- JP2020500528A5 JP2020500528A5 JP2019529497A JP2019529497A JP2020500528A5 JP 2020500528 A5 JP2020500528 A5 JP 2020500528A5 JP 2019529497 A JP2019529497 A JP 2019529497A JP 2019529497 A JP2019529497 A JP 2019529497A JP 2020500528 A5 JP2020500528 A5 JP 2020500528A5
- Authority
- JP
- Japan
- Prior art keywords
- nanopore
- sample
- adapter
- strand
- tag
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1620450.5 | 2016-12-01 | ||
| GBGB1620450.5A GB201620450D0 (en) | 2016-12-01 | 2016-12-01 | Method |
| US201762471338P | 2017-03-14 | 2017-03-14 | |
| US62/471,338 | 2017-03-14 | ||
| PCT/GB2017/053603 WO2018100370A1 (en) | 2016-12-01 | 2017-11-29 | Methods and systems for characterizing analytes using nanopores |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020500528A JP2020500528A (ja) | 2020-01-16 |
| JP2020500528A5 true JP2020500528A5 (enExample) | 2021-01-14 |
| JP7055805B2 JP7055805B2 (ja) | 2022-04-18 |
Family
ID=58159754
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019529497A Active JP7055805B2 (ja) | 2016-12-01 | 2017-11-29 | ナノポアを用いて検体を特徴付けるための方法及びシステム |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US11466317B2 (enExample) |
| EP (2) | EP4269617A3 (enExample) |
| JP (1) | JP7055805B2 (enExample) |
| CN (3) | CN116377044B (enExample) |
| AU (1) | AU2017367238B2 (enExample) |
| CA (1) | CA3044351A1 (enExample) |
| GB (1) | GB201620450D0 (enExample) |
| WO (1) | WO2018100370A1 (enExample) |
Families Citing this family (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6226869B2 (ja) | 2011-10-21 | 2017-11-08 | オックスフォード ナノポール テクノロジーズ リミテッド | 酵素法 |
| AU2013291763B2 (en) | 2012-07-19 | 2019-06-20 | Oxford Nanopore Technologies Limited | Modified helicases |
| GB201222928D0 (en) | 2012-12-19 | 2013-01-30 | Oxford Nanopore Tech Ltd | Analysis of a polynucleotide |
| CA2927726A1 (en) | 2013-10-18 | 2015-04-23 | Oxford Nanopore Technologies Limited | Modified helicases for use in nucleic acid sequencing |
| GB201417712D0 (en) | 2014-10-07 | 2014-11-19 | Oxford Nanopore Tech Ltd | Method |
| GB201609221D0 (en) | 2016-05-25 | 2016-07-06 | Oxford Nanopore Tech Ltd | Method |
| WO2017203268A1 (en) | 2016-05-25 | 2017-11-30 | Oxford Nanopore Technologies Limited | Method |
| GB201620450D0 (en) * | 2016-12-01 | 2017-01-18 | Oxford Nanopore Tech Ltd | Method |
| GB201707140D0 (en) | 2017-05-04 | 2017-06-21 | Oxford Nanopore Tech Ltd | Method |
| GB2569630B (en) | 2017-12-21 | 2022-10-12 | Sharp Life Science Eu Ltd | Droplet Interfaces in Electro-wetting Devices |
| WO2019226689A1 (en) | 2018-05-22 | 2019-11-28 | Axbio Inc. | Methods, systems, and compositions for nucleic acid sequencing |
| CN112203767B (zh) | 2018-05-24 | 2023-04-11 | 牛津纳米孔科技公司 | 电润湿装置中的液滴界面 |
| GB201809323D0 (en) | 2018-06-06 | 2018-07-25 | Oxford Nanopore Tech Ltd | Method |
| GB2585816A (en) * | 2018-12-12 | 2021-01-27 | Univ York | Proof-of-work for blockchain applications |
| CN111455031A (zh) * | 2019-01-18 | 2020-07-28 | 中国科学院微生物研究所 | 基于Nanopore测序技术的多组学测序及分析方法 |
| KR20210138594A (ko) * | 2019-03-12 | 2021-11-19 | 옥스포드 나노포어 테크놀로지즈 피엘씨 | 나노포어 감지 디바이스 및 이를 작동하는 방법 및 형성하는 방법 |
| GB201907243D0 (en) | 2019-05-22 | 2019-07-03 | Oxford Nanopore Tech Ltd | Sensing interactions between molecular entities and nanapores |
| GB2603061A (en) * | 2019-09-18 | 2022-07-27 | Hitachi High Tech Corp | Adapter molecule, biomolecule-adapter molecule complex composed of adapter molecule and biomolecule bound together, biomolecule analyzer and biomolecule |
| WO2021163163A1 (en) * | 2020-02-10 | 2021-08-19 | Palogen, Inc. | Nanopore device and methods of detecting and classifying charged particles using same |
| EP3991211A4 (en) * | 2020-03-20 | 2022-07-20 | GeneSense Technology Inc. | High throughput analytical system for molecule detection and sensing |
| CN115698331A (zh) | 2020-06-18 | 2023-02-03 | 牛津纳米孔科技公开有限公司 | 使用检测器选择性地表征多核苷酸的方法 |
| CN113930406B (zh) * | 2021-12-17 | 2022-04-08 | 北京齐碳科技有限公司 | 一种Pif1-like解旋酶及其应用 |
| MX2022014721A (es) * | 2020-07-06 | 2023-03-06 | Illumina Inc | Separacion de fragmentos de polinucleotidos. |
| CN112309503A (zh) * | 2020-10-19 | 2021-02-02 | 深圳市儒翰基因科技有限公司 | 基于纳米孔电信号的碱基判读方法、判读设备及存储介质 |
| US12090477B2 (en) * | 2021-03-05 | 2024-09-17 | Taiwan Semiconductor Manufacturing Company Ltd. | System and method for detecting biomolecules |
| GB202107192D0 (en) * | 2021-05-19 | 2021-06-30 | Oxford Nanopore Tech Ltd | Method |
| CN117337333A (zh) | 2021-05-19 | 2024-01-02 | 牛津纳米孔科技公开有限公司 | 用于补体链测序的方法 |
| CN113322180B (zh) * | 2021-05-31 | 2022-07-15 | 中国科学院物理研究所 | 基于纳米孔测序的力谱分析方法和分析装置 |
| CN115537413A (zh) * | 2021-06-29 | 2022-12-30 | 中国农业大学 | 一种双链功能核酸纳米花的组装和形貌调控方法及其应用 |
| CN113462764B (zh) * | 2021-09-01 | 2021-12-17 | 北京齐碳科技有限公司 | 用于表征双链靶多核苷酸的类发夹衔接子、构建体和方法 |
| WO2023055752A2 (en) | 2021-09-28 | 2023-04-06 | Axbio Inc. | Methods for processing a nucleic acid sample and compositions thereof |
| CN114134142B (zh) * | 2021-11-23 | 2024-05-28 | 成都齐碳科技有限公司 | 衔接体、复合物、单链分子、试剂盒、方法和应用 |
| WO2023125605A1 (zh) * | 2021-12-30 | 2023-07-06 | 深圳华大生命科学研究院 | 单分子纳米孔测序方法 |
| US20250136974A1 (en) * | 2021-12-31 | 2025-05-01 | Bgi Shenzhen | Nucleic acid molecule capable of blocking motor protein, and construction method and application thereof |
| EP4519453A1 (en) | 2022-05-06 | 2025-03-12 | 10X Genomics, Inc. | Methods and compositions for in situ analysis of v(d)j sequences |
| WO2023222657A1 (en) | 2022-05-17 | 2023-11-23 | Oxford Nanopore Technologies Plc | Method and adaptors |
| GB202207267D0 (en) | 2022-05-18 | 2022-06-29 | Oxford Nanopore Tech Plc | Calibration and profiling of a nanopore array device |
| WO2024077281A2 (en) * | 2022-10-06 | 2024-04-11 | Cornell University | Genotyping and sequencing assays for prrsv |
| GB202215442D0 (en) | 2022-10-19 | 2022-11-30 | Oxford Nanopore Tech Plc | Analysis of a polymer |
| EP4605552A2 (en) * | 2022-10-21 | 2025-08-27 | Axbio Inc. | Systems and methods for analyzing a target molecule |
| GB202216905D0 (en) | 2022-11-11 | 2022-12-28 | Oxford Nanopore Tech Plc | Novel pore monomers and pores |
| WO2024101988A1 (en) | 2022-11-11 | 2024-05-16 | Umc Utrecht Holding B.V. | Computer-implemented method for identifying a dna modification |
| CN116478983B (zh) * | 2022-11-21 | 2023-10-24 | 北京普译生物科技有限公司 | 一种rna-dna嵌合接头及其应用 |
| EP4636094A1 (en) * | 2022-12-16 | 2025-10-22 | BGI Shenzhen | Nanopore sequencing method and kit |
| GB202301095D0 (en) | 2023-01-25 | 2023-03-08 | Oxford Nanopore Tech Plc | Calibration of a nanopore array device |
| GB202304324D0 (en) | 2023-03-24 | 2023-05-10 | Oxford Nanopore Tech Plc | Method and kits |
| GB202305524D0 (en) | 2023-04-14 | 2023-05-31 | Oxford Nanopore Tech Plc | Novel pore monomers and pores |
| GB202307141D0 (en) | 2023-05-12 | 2023-06-28 | Oxford Nanopore Tech Plc | Modified helicases |
| WO2025000432A1 (zh) * | 2023-06-30 | 2025-01-02 | 深圳华大生命科学研究院 | 利用封闭子进行纳米孔测序的方法 |
| WO2025223677A1 (en) * | 2024-04-26 | 2025-10-30 | Helmholtz-Zentrum für Infektionsforschung GmbH | Method for analyzing molecules of interest, method for automatically selecting electrical signals related to a set of known barcode molecules, signal processing unit and computer program for executing the method |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20120160687A1 (en) | 1995-03-17 | 2012-06-28 | President And Fellows Of Harvard College | Characterization of individual polymer molecules based on monomer-interface interactions |
| US6362002B1 (en) | 1995-03-17 | 2002-03-26 | President And Fellows Of Harvard College | Characterization of individual polymer molecules based on monomer-interface interactions |
| US6267872B1 (en) | 1998-11-06 | 2001-07-31 | The Regents Of The University Of California | Miniature support for thin films containing single channels or nanopores and methods for using same |
| US6465193B2 (en) | 1998-12-11 | 2002-10-15 | The Regents Of The University Of California | Targeted molecular bar codes and methods for using the same |
| AU2001241474A1 (en) * | 2000-02-11 | 2001-08-20 | The Texas A And M University System | Biosensor compositions and methods of use |
| FR2814939B1 (fr) | 2000-10-05 | 2002-12-20 | Sofradim Production | Ensemble de soutenement sous-uretral dans le traitement de l'incontinence urinaire d'effort de la femme |
| US20020197618A1 (en) | 2001-01-20 | 2002-12-26 | Sampson Jeffrey R. | Synthesis and amplification of unstructured nucleic acids for rapid sequencing |
| US8278055B2 (en) | 2002-05-01 | 2012-10-02 | Intel Corporation | Methods and device for analyte characterization |
| WO2005124888A1 (en) | 2004-06-08 | 2005-12-29 | President And Fellows Of Harvard College | Suspended carbon nanotube field effect transistor |
| GB0505971D0 (en) | 2005-03-23 | 2005-04-27 | Isis Innovation | Delivery of molecules to a lipid bilayer |
| NZ579083A (en) | 2007-02-20 | 2012-07-27 | Oxford Nanopore Tech Ltd | Lipid bilayer sensor system |
| WO2009035647A1 (en) | 2007-09-12 | 2009-03-19 | President And Fellows Of Harvard College | High-resolution molecular graphene sensor comprising an aperture in the graphene layer |
| GB0724736D0 (en) | 2007-12-19 | 2008-01-30 | Oxford Nanolabs Ltd | Formation of layers of amphiphilic molecules |
| US20110229877A1 (en) * | 2008-07-07 | 2011-09-22 | Oxford Nanopore Technologies Limited | Enzyme-pore constructs |
| GB0820927D0 (en) | 2008-11-14 | 2008-12-24 | Isis Innovation | Method |
| CA2750874A1 (en) | 2009-01-30 | 2010-08-05 | Oxford Nanopore Technologies Limited | Hybridization linkers |
| GB0901588D0 (en) | 2009-02-02 | 2009-03-11 | Itis Holdings Plc | Apparatus and methods for providing journey information |
| BR112012013074B1 (pt) | 2009-12-01 | 2018-09-18 | Oxford Nanopore Technologies Limited | instrumento de análise e módulo para realizar análise bioquímica, e, método para operar um instrumento de análise para realizar análise bioquímica |
| US8586301B2 (en) | 2010-06-30 | 2013-11-19 | Stratos Genomics, Inc. | Multiplexed identification of nucleic acid sequences |
| CN103370617B (zh) | 2010-10-01 | 2015-11-25 | 牛津纳米孔技术有限公司 | 生物化学分析设备和旋转阀 |
| KR101939420B1 (ko) | 2011-02-11 | 2019-01-16 | 옥스포드 나노포어 테크놀로지즈 리미티드 | 돌연변이체 세공 |
| US9347929B2 (en) | 2011-03-01 | 2016-05-24 | The Regents Of The University Of Michigan | Controlling translocation through nanopores with fluid wall |
| AU2012264497B2 (en) * | 2011-05-27 | 2017-06-15 | Oxford Nanopore Technologies Limited | Coupling method |
| JP6298404B2 (ja) | 2011-07-25 | 2018-03-20 | オックスフォード ナノポール テクノロジーズ リミテッド | 膜貫通ポアを用いる二重鎖ポリヌクレオチド配列決定のためのヘアピンループ方法 |
| WO2013041878A1 (en) | 2011-09-23 | 2013-03-28 | Oxford Nanopore Technologies Limited | Analysis of a polymer comprising polymer units |
| JP6226869B2 (ja) | 2011-10-21 | 2017-11-08 | オックスフォード ナノポール テクノロジーズ リミテッド | 酵素法 |
| KR102086182B1 (ko) | 2011-12-29 | 2020-03-06 | 옥스포드 나노포어 테크놀로지즈 리미티드 | 효소 방법 |
| EP2798083B1 (en) | 2011-12-29 | 2017-08-09 | Oxford Nanopore Technologies Limited | Method for characterising a polynucelotide by using a xpd helicase |
| EP3415901A1 (en) * | 2012-01-20 | 2018-12-19 | Genia Technologies, Inc. | Nanopore based molecular detection and sequencing |
| EP2814959B1 (en) | 2012-02-17 | 2018-01-17 | Fred Hutchinson Cancer Research Center | Compositions and methods for accurately identifying mutations |
| CN112646019B (zh) * | 2012-04-10 | 2022-08-16 | 牛津纳米孔科技公开有限公司 | 突变胞溶素孔 |
| WO2013181170A1 (en) | 2012-05-31 | 2013-12-05 | Board Of Regents, The University Of Texas System | Method for accurate sequencing of dna |
| WO2013185137A1 (en) * | 2012-06-08 | 2013-12-12 | Pacific Biosciences Of California, Inc. | Modified base detection with nanopore sequencing |
| EP2864502B1 (en) * | 2012-06-20 | 2019-10-23 | The Trustees of Columbia University in the City of New York | Nucleic acid sequencing by nanopore detection of tag molecules |
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| US9797009B2 (en) | 2012-07-19 | 2017-10-24 | Oxford Nanopore Technologies Limited | Enzyme construct |
| AU2013291763B2 (en) | 2012-07-19 | 2019-06-20 | Oxford Nanopore Technologies Limited | Modified helicases |
| US9823235B2 (en) | 2012-10-26 | 2017-11-21 | Oxford Nanopre Technologies Ltd. | Droplet interfaces |
| GB201313121D0 (en) | 2013-07-23 | 2013-09-04 | Oxford Nanopore Tech Ltd | Array of volumes of polar medium |
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| CN105102627B (zh) | 2013-03-15 | 2018-10-19 | 纽约哥伦比亚大学理事会 | 用于检测样品中多种预定化合物的方法 |
| CN203450281U (zh) | 2013-08-01 | 2014-02-26 | 大行科技(深圳)有限公司 | 一种折叠自行车走线结构 |
| GB201406151D0 (en) | 2014-04-04 | 2014-05-21 | Oxford Nanopore Tech Ltd | Method |
| CA2927726A1 (en) | 2013-10-18 | 2015-04-23 | Oxford Nanopore Technologies Limited | Modified helicases for use in nucleic acid sequencing |
| GB201406155D0 (en) | 2014-04-04 | 2014-05-21 | Oxford Nanopore Tech Ltd | Method |
| EP3097210B2 (en) | 2014-01-22 | 2022-04-20 | Oxford Nanopore Technologies Limited | Method for attaching one or more polynucleotide binding proteins to a target polynucleotide |
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| WO2015127387A1 (en) | 2014-02-21 | 2015-08-27 | Northeastern University | Fluorescence-based analysis of biopolymers using nanopores |
| US20170096703A1 (en) | 2014-03-21 | 2017-04-06 | Oxford Nanopore Technologies Ltd. | Analysis of a polymer from multi-dimensional measurements |
| EP3126515B1 (en) | 2014-04-04 | 2018-08-29 | Oxford Nanopore Technologies Limited | Method for characterising a double stranded nucleic acid using a nano-pore and anchor molecules at both ends of said nucleic acid |
| GB201417712D0 (en) | 2014-10-07 | 2014-11-19 | Oxford Nanopore Tech Ltd | Method |
| US10400014B2 (en) * | 2014-09-01 | 2019-09-03 | Oxford Nanopore Technologies Ltd. | Mutant CsgG pores |
| GB201418159D0 (en) | 2014-10-14 | 2014-11-26 | Oxford Nanopore Tech Ltd | Method |
| CN115851894B (zh) | 2014-10-16 | 2025-06-27 | 牛津楠路珀尔科技股份有限公司 | 聚合物的分析 |
| CN107109489B (zh) | 2014-10-17 | 2021-11-30 | 牛津纳米孔技术公司 | 纳米孔rna表征方法 |
| GB201418469D0 (en) | 2014-10-17 | 2014-12-03 | Oxford Nanopore Tech Ltd | Method |
| US9557294B2 (en) * | 2014-12-19 | 2017-01-31 | Genia Technologies, Inc. | Nanopore-based sequencing with varying voltage stimulus |
| AU2016220404B2 (en) * | 2015-02-17 | 2021-05-27 | Mgi Tech Co., Ltd. | DNA sequencing using controlled strand displacement |
| KR102782598B1 (ko) | 2015-06-25 | 2025-03-14 | 로스웰 엠이 아이엔씨. | 바이오분자 센서들 및 방법들 |
| WO2017125565A1 (en) | 2016-01-21 | 2017-07-27 | Genia Technologies, Inc. | Nanopore sequencing complexes |
| GB201609221D0 (en) | 2016-05-25 | 2016-07-06 | Oxford Nanopore Tech Ltd | Method |
| GB201620450D0 (en) | 2016-12-01 | 2017-01-18 | Oxford Nanopore Tech Ltd | Method |
| GB201809323D0 (en) | 2018-06-06 | 2018-07-25 | Oxford Nanopore Tech Ltd | Method |
-
2016
- 2016-12-01 GB GBGB1620450.5A patent/GB201620450D0/en not_active Ceased
-
2017
- 2017-11-29 AU AU2017367238A patent/AU2017367238B2/en active Active
- 2017-11-29 EP EP23182828.6A patent/EP4269617A3/en active Pending
- 2017-11-29 CN CN202310379925.0A patent/CN116377044B/zh active Active
- 2017-11-29 EP EP17817029.6A patent/EP3548636B1/en active Active
- 2017-11-29 JP JP2019529497A patent/JP7055805B2/ja active Active
- 2017-11-29 WO PCT/GB2017/053603 patent/WO2018100370A1/en not_active Ceased
- 2017-11-29 CN CN201780083105.XA patent/CN110168104A/zh active Pending
- 2017-11-29 US US16/465,987 patent/US11466317B2/en active Active
- 2017-11-29 CA CA3044351A patent/CA3044351A1/en active Pending
- 2017-11-29 CN CN202310379929.9A patent/CN116334200B/zh active Active
-
2022
- 2022-08-03 US US17/817,065 patent/US20230084931A1/en active Pending
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