JP2020114264A5 - - Google Patents
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- JP2020114264A5 JP2020114264A5 JP2020081118A JP2020081118A JP2020114264A5 JP 2020114264 A5 JP2020114264 A5 JP 2020114264A5 JP 2020081118 A JP2020081118 A JP 2020081118A JP 2020081118 A JP2020081118 A JP 2020081118A JP 2020114264 A5 JP2020114264 A5 JP 2020114264A5
- Authority
- JP
- Japan
- Prior art keywords
- fusion protein
- seq
- amino acid
- acid sequence
- intracellular
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021150184A JP7441201B2 (ja) | 2015-03-05 | 2021-09-15 | 免疫調節性融合タンパク質およびその使用 |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562128979P | 2015-03-05 | 2015-03-05 | |
| US62/128,979 | 2015-03-05 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017546715A Division JP6917896B2 (ja) | 2015-03-05 | 2016-03-04 | 免疫調節性融合タンパク質およびその使用 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021150184A Division JP7441201B2 (ja) | 2015-03-05 | 2021-09-15 | 免疫調節性融合タンパク質およびその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020114264A JP2020114264A (ja) | 2020-07-30 |
| JP2020114264A5 true JP2020114264A5 (OSRAM) | 2020-11-12 |
| JP7026161B2 JP7026161B2 (ja) | 2022-02-25 |
Family
ID=55587371
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017546715A Active JP6917896B2 (ja) | 2015-03-05 | 2016-03-04 | 免疫調節性融合タンパク質およびその使用 |
| JP2020081118A Expired - Fee Related JP7026161B2 (ja) | 2015-03-05 | 2020-05-01 | 免疫調節性融合タンパク質およびその使用 |
| JP2021150184A Active JP7441201B2 (ja) | 2015-03-05 | 2021-09-15 | 免疫調節性融合タンパク質およびその使用 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017546715A Active JP6917896B2 (ja) | 2015-03-05 | 2016-03-04 | 免疫調節性融合タンパク質およびその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021150184A Active JP7441201B2 (ja) | 2015-03-05 | 2021-09-15 | 免疫調節性融合タンパク質およびその使用 |
Country Status (17)
| Country | Link |
|---|---|
| US (3) | US20180044404A1 (OSRAM) |
| EP (2) | EP4406604A3 (OSRAM) |
| JP (3) | JP6917896B2 (OSRAM) |
| KR (1) | KR20170120701A (OSRAM) |
| CN (1) | CN107531805A (OSRAM) |
| AU (3) | AU2016226022B2 (OSRAM) |
| BR (1) | BR112017018919A8 (OSRAM) |
| CA (2) | CA2978186A1 (OSRAM) |
| ES (1) | ES2979088T3 (OSRAM) |
| HK (1) | HK1246317A1 (OSRAM) |
| IL (1) | IL254165B (OSRAM) |
| MX (4) | MX2017011201A (OSRAM) |
| MY (2) | MY196588A (OSRAM) |
| RU (1) | RU2755227C2 (OSRAM) |
| SA (1) | SA517382216B1 (OSRAM) |
| SG (2) | SG11201707182WA (OSRAM) |
| WO (1) | WO2016141357A1 (OSRAM) |
Families Citing this family (66)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG11201505858VA (en) | 2013-01-28 | 2015-09-29 | St Jude Childrens Res Hospital | A chimeric receptor with nkg2d specificity for use in cell therapy against cancer and infectious disease |
| EP3805371A1 (en) | 2014-05-15 | 2021-04-14 | National University of Singapore | Modified natural killer cells and uses thereof |
| CN107206024B (zh) | 2014-10-31 | 2021-12-03 | 宾夕法尼亚大学董事会 | 改变cart细胞中的基因表达及其用途 |
| MY196588A (en) | 2015-03-05 | 2023-04-19 | Hutchinson Fred Cancer Res | Immunomodulatory Fusion Proteins and uses Thereof |
| IL303905A (en) | 2015-05-18 | 2023-08-01 | Tcr2 Therapeutics Inc | Compositions and methods for TCR programming using fusion proteins |
| US11026969B2 (en) | 2015-12-23 | 2021-06-08 | Fred Hutchinson Cancer Research Center | High affinity T cell receptors and uses thereof |
| US11365237B2 (en) * | 2016-03-23 | 2022-06-21 | Helmholtz Zentrum Muenchen—Deutsches Forschungszentrum Fuer Gesundheit Und Umwelt (Gmbh) | Fusion proteins of PD-1 and 4-1BB |
| KR20190019068A (ko) | 2016-05-18 | 2019-02-26 | 큐 바이오파마, 인크. | T-세포 조절 다량체 폴리펩타이드 및 이의 사용 방법 |
| WO2018009972A1 (en) * | 2016-07-14 | 2018-01-18 | Peter Maccallum Cancer Institute | Chimeric antigen receptor modified t cells |
| SG10201911972QA (en) | 2016-07-14 | 2020-02-27 | Bristol Myers Squibb Co | Antibodies against tim3 and uses thereof |
| AU2017363311A1 (en) | 2016-11-22 | 2019-06-13 | TCR2 Therapeutics Inc. | Compositions and methods for TCR reprogramming using fusion proteins |
| WO2018102761A1 (en) * | 2016-12-02 | 2018-06-07 | City Of Hope | Methods for manufacturing and expanding t cells expressing chimeric antigen receptors and other receptors |
| PT3558339T (pt) | 2016-12-22 | 2024-03-15 | Cue Biopharma Inc | Polipeptídeos multiméricos moduladores de células t e métodos de utilização dos mesmos |
| JP2020512284A (ja) * | 2016-12-22 | 2020-04-23 | ウィンドミル セラピューティクス インコーポレイテッド | 免疫系調節組成物および方法 |
| US11851471B2 (en) | 2017-01-09 | 2023-12-26 | Cue Biopharma, Inc. | T-cell modulatory multimeric polypeptides and methods of use thereof |
| CA3054955A1 (en) | 2017-03-15 | 2018-09-20 | Cue Biopharma, Inc. | Methods for modulating an immune response |
| JP2020511136A (ja) * | 2017-03-17 | 2020-04-16 | フレッド ハッチンソン キャンサー リサーチ センター | 免疫調節性融合タンパク質およびその使用 |
| CA3056439A1 (en) | 2017-03-27 | 2018-10-04 | National University Of Singapore | Truncated nkg2d chimeric receptors and uses thereof in natural killer cell immunotherapy |
| SG11201908337VA (en) | 2017-03-27 | 2019-10-30 | Nat Univ Singapore | Stimulatory cell lines for ex vivo expansion and activation of natural killer cells |
| BR112020001679A2 (pt) | 2017-08-02 | 2020-07-21 | Phanes Therapeutics, Inc. | anticorpos anti-cd47 e usos dos mesmos |
| US10960071B2 (en) | 2017-08-07 | 2021-03-30 | The Regents Of The University Of California | Platform for generating safe cell therapeutics |
| US20200368285A1 (en) | 2017-08-07 | 2020-11-26 | The Regents Of The University Of California | Platform for generating safe cell therapeutics |
| AU2018328283A1 (en) * | 2017-09-07 | 2020-02-20 | Cue Biopharma, Inc. | Antigen-presenting polypeptides and methods of use thereof |
| WO2019055862A1 (en) | 2017-09-14 | 2019-03-21 | Fred Hutchinson Cancer Research Center | HIGH AFFINITY T CELL RECEPTORS AND USES THEREOF |
| WO2019090355A1 (en) * | 2017-11-06 | 2019-05-09 | Children's National Medical Center | Cells expressing antibodies and methods of treatment using the same |
| US11866731B2 (en) | 2017-11-10 | 2024-01-09 | Chineo Medical Technology Co., Ltd | Modified immune cells and uses thereof |
| EP3737689A4 (en) | 2018-01-09 | 2021-12-01 | Cue Biopharma, Inc. | MULTIMER POLYPEPTIDES T-LYMPHOCYTE MODULATORS AND THEIR METHODS OF USE |
| SG11202007156QA (en) | 2018-02-09 | 2020-08-28 | Nat Univ Singapore | Activating chimeric receptors and uses thereof in natural killer cell immunotherapy |
| SG11202008976YA (en) | 2018-04-02 | 2020-10-29 | Nat Univ Singapore | Neutralization of human cytokines with membrane-bound anti-cytokine non-signaling binders expressed in immune cells |
| CN112566650A (zh) * | 2018-06-21 | 2021-03-26 | 沙塔克实验室有限公司 | 异二聚体蛋白及其用途 |
| KR102839381B1 (ko) | 2018-08-29 | 2025-07-28 | 내셔널 유니버시티 오브 싱가포르 | 유전적으로 변형된 면역 세포의 생존 및 확장을 특이적으로 자극하는 방법 |
| US12331320B2 (en) | 2018-10-10 | 2025-06-17 | The Research Foundation For The State University Of New York | Genome edited cancer cell vaccines |
| KR102261407B1 (ko) * | 2018-10-10 | 2021-06-08 | 한국화학연구원 | Hvem을 표적으로 하는 키메라 항원 수용체 |
| WO2020102240A1 (en) * | 2018-11-13 | 2020-05-22 | Memorial Sloan Kettering Cancer Center | Compositions and methods for adoptive cell therapy for cancer |
| TWI856047B (zh) | 2018-12-19 | 2024-09-21 | 美商信號生物製藥公司 | 多聚體ｔ細胞調節多肽及其使用方法 |
| GB201900858D0 (en) * | 2019-01-22 | 2019-03-13 | Price Nicola Kaye | Receptors providing targeted costimulation for adoptive cell therapy |
| AU2020232691B2 (en) | 2019-03-05 | 2023-06-29 | Nkarta, Inc. | CD19-directed chimeric antigen receptors and uses thereof in immunotherapy |
| CA3132845A1 (en) | 2019-03-11 | 2020-09-17 | Fred Hutchinson Cancer Research Center | High avidity wt1 t cell receptors and uses thereof |
| WO2020190771A1 (en) * | 2019-03-15 | 2020-09-24 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Chimeric adaptor and kinase signaling proteins and their use in immunotherapy |
| MX2021011373A (es) * | 2019-03-21 | 2022-01-06 | Onk Therapeutics Ltd | Celulas efectoras inmunitarias modificadas con mayor resistencia a la muerte celular. |
| JP7711945B2 (ja) | 2019-04-30 | 2025-07-23 | センティ バイオサイエンシズ インコーポレイテッド | キメラ受容体及びその使用方法 |
| AU2020315796A1 (en) * | 2019-07-19 | 2022-02-24 | Memorial Hospital For Cancer And Allied Diseases | Fusion polypeptide for immunotherapy |
| CN114929751B (zh) * | 2019-09-27 | 2024-11-05 | 南京艾美斐生物医药科技有限公司 | Ror1特异性嵌合抗原受体及其治疗应用 |
| CN115989034A (zh) * | 2019-11-27 | 2023-04-18 | 得克萨斯大学体系董事会 | Nk细胞的大规模组合car转导和crispr基因编辑 |
| EP4066842A4 (en) * | 2019-11-29 | 2023-01-25 | Suzhou Nova Therapeutics Co. Ltd | APPLICATION OF CAR-T CELLS IN MANUFACTURE OF DRUG FOR TREATMENT OF CANCER |
| IL293718A (en) * | 2019-12-11 | 2022-08-01 | Myeloid Therapeutics Inc | Therapeutic cell compositions and methods for manufacture and uses thereof |
| US20230293689A1 (en) * | 2020-01-19 | 2023-09-21 | Chineo Medical Technology Co., Ltd. | Strengthened receptor for improving immune cell function |
| GB202101491D0 (en) * | 2021-02-03 | 2021-03-17 | Autolus Ltd | Molecule |
| EP4132962A1 (en) * | 2020-04-09 | 2023-02-15 | Autolus Limited | Molecule |
| CN115315439A (zh) * | 2020-04-09 | 2022-11-08 | 奥托路斯有限公司 | 细胞 |
| WO2021231376A2 (en) | 2020-05-12 | 2021-11-18 | Cue Biopharma, Inc. | Multimeric t-cell modulatory polypeptides and methods of use thereof |
| CN113698490B (zh) * | 2020-05-22 | 2024-04-30 | 重庆精准生物技术有限公司 | 靶向cea的缺氧诱导启动的car结构及免疫细胞和应用 |
| CN116348485A (zh) | 2020-07-17 | 2023-06-27 | 英研生物(英国)有限公司 | 提供用于过继性细胞疗法的靶向共刺激的受体 |
| WO2022020745A1 (en) * | 2020-07-23 | 2022-01-27 | Emory University | Galectin-9 specific binding agents for use in treating cancer |
| JP2023541366A (ja) | 2020-09-09 | 2023-10-02 | キュー バイオファーマ， インコーポレイテッド | １型真性糖尿病（ｔ１ｄ）を治療するためのｍｈｃクラスｉｉ ｔ細胞調節多量体ポリペプチド及びその使用方法 |
| CA3211402A1 (en) * | 2021-03-10 | 2022-09-15 | Moshe ELKABETS | Reporter cells expressing chimeric polypeptides for use in determining presence and or activity of immune checkpoint molecules |
| WO2022246041A2 (en) * | 2021-05-20 | 2022-11-24 | Achelois Biopharma, Inc. | Compositions and methods for multivalent surface display on enveloped particles |
| EP4340862A4 (en) * | 2021-05-20 | 2025-05-21 | Achelois Biopharma, Inc. | Immune checkpoint multivalent particles compositions and methods of use |
| TW202306997A (zh) | 2021-06-16 | 2023-02-16 | 英商英斯特生物科技有限公司 | 用於在過繼細胞療法中提供標靶共刺激之受體 |
| WO2023288278A1 (en) | 2021-07-16 | 2023-01-19 | Instil Bio (Uk) Limited | Chimeric molecules providing targeted costimulation for adoptive cell therapy |
| CN113621077B (zh) * | 2021-09-02 | 2023-01-31 | 山东大学 | 一种tim-3/cd28融合蛋白及所述融合蛋白修饰的car-t细胞 |
| WO2023150801A2 (en) * | 2022-02-07 | 2023-08-10 | Seattle Children's Hospital D/B/A Seattle Children's Research Institute | Recombinant proteins that stimulate an immune response in the presence of naturally inhibitory ligand binding |
| KR20250121414A (ko) * | 2022-12-15 | 2025-08-12 | 칼리버 임뮤노쎄라퓨틱스, 인크. | Cd47/sirp-알파 면역 체크포인트 억제제 조성물 및 그의 용도 |
| WO2025081123A1 (en) | 2023-10-12 | 2025-04-17 | Fred Hutchinson Cancer Center | Methods and compositions for improving t cell immunotherapy |
| EP4599843A1 (en) | 2024-02-09 | 2025-08-13 | Fundació Institut de recerca de l'Hospital de la Santa Creu i Sant Pau | Car and modified cd200r combination |
| WO2025245169A1 (en) | 2024-05-21 | 2025-11-27 | Fred Hutchinson Cancer Center | Immunotherapy cells equipped with a collagen-targeting payload |
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-
2016
- 2016-03-04 MY MYPI2021007596A patent/MY196588A/en unknown
- 2016-03-04 MX MX2017011201A patent/MX2017011201A/es unknown
- 2016-03-04 US US15/555,951 patent/US20180044404A1/en not_active Abandoned
- 2016-03-04 EP EP24169396.9A patent/EP4406604A3/en not_active Withdrawn
- 2016-03-04 RU RU2017133637A patent/RU2755227C2/ru active
- 2016-03-04 EP EP16711081.6A patent/EP3265481B1/en active Active
- 2016-03-04 SG SG11201707182WA patent/SG11201707182WA/en unknown
- 2016-03-04 KR KR1020177027794A patent/KR20170120701A/ko active Pending
- 2016-03-04 AU AU2016226022A patent/AU2016226022B2/en not_active Ceased
- 2016-03-04 WO PCT/US2016/021064 patent/WO2016141357A1/en not_active Ceased
- 2016-03-04 HK HK18105732.2A patent/HK1246317A1/zh unknown
- 2016-03-04 JP JP2017546715A patent/JP6917896B2/ja active Active
- 2016-03-04 ES ES16711081T patent/ES2979088T3/es active Active
- 2016-03-04 MY MYPI2017001281A patent/MY189195A/en unknown
- 2016-03-04 CN CN201680023758.4A patent/CN107531805A/zh active Pending
- 2016-03-04 CA CA2978186A patent/CA2978186A1/en active Pending
- 2016-03-04 CA CA3177938A patent/CA3177938A1/en active Pending
- 2016-03-04 BR BR112017018919A patent/BR112017018919A8/pt not_active Application Discontinuation
- 2016-03-04 SG SG10201908203S patent/SG10201908203SA/en unknown
-
2017
- 2017-08-27 IL IL254165A patent/IL254165B/en unknown
- 2017-08-30 SA SA517382216A patent/SA517382216B1/ar unknown
- 2017-08-31 MX MX2022006002A patent/MX2022006002A/es unknown
- 2017-08-31 MX MX2022006004A patent/MX2022006004A/es unknown
- 2017-08-31 MX MX2022006006A patent/MX2022006006A/es unknown
-
2020
- 2020-05-01 JP JP2020081118A patent/JP7026161B2/ja not_active Expired - Fee Related
- 2020-09-30 AU AU2020244495A patent/AU2020244495B2/en not_active Ceased
-
2021
- 2021-02-03 US US17/166,903 patent/US12012443B2/en active Active
- 2021-09-15 JP JP2021150184A patent/JP7441201B2/ja active Active
-
2022
- 2022-11-16 AU AU2022271411A patent/AU2022271411A1/en not_active Abandoned
-
2024
- 2024-05-07 US US18/657,687 patent/US20250109180A1/en active Pending
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