JP2020089382A5 - - Google Patents
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- JP2020089382A5 JP2020089382A5 JP2020009595A JP2020009595A JP2020089382A5 JP 2020089382 A5 JP2020089382 A5 JP 2020089382A5 JP 2020009595 A JP2020009595 A JP 2020009595A JP 2020009595 A JP2020009595 A JP 2020009595A JP 2020089382 A5 JP2020089382 A5 JP 2020089382A5
- Authority
- JP
- Japan
- Prior art keywords
- compound according
- modified
- nucleoside
- wing
- antisense oligonucleotide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30246910P | 2010-02-08 | 2010-02-08 | |
| US61/302,469 | 2010-02-08 | ||
| US37163510P | 2010-08-06 | 2010-08-06 | |
| US61/371,635 | 2010-08-06 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018055560A Division JP6652984B2 (ja) | 2010-02-08 | 2018-03-23 | 対立遺伝子多様体の選択的低減 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020089382A JP2020089382A (ja) | 2020-06-11 |
| JP2020089382A5 true JP2020089382A5 (https=) | 2020-11-12 |
Family
ID=44355846
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012552932A Active JP6006120B2 (ja) | 2010-02-08 | 2011-02-08 | 対立遺伝子多様体の選択的低減 |
| JP2016078592A Active JP6316334B2 (ja) | 2010-02-08 | 2016-04-11 | 対立遺伝子多様体の選択的低減 |
| JP2018055560A Active JP6652984B2 (ja) | 2010-02-08 | 2018-03-23 | 対立遺伝子多様体の選択的低減 |
| JP2020009595A Pending JP2020089382A (ja) | 2010-02-08 | 2020-01-24 | 対立遺伝子多様体の選択的低減 |
Family Applications Before (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012552932A Active JP6006120B2 (ja) | 2010-02-08 | 2011-02-08 | 対立遺伝子多様体の選択的低減 |
| JP2016078592A Active JP6316334B2 (ja) | 2010-02-08 | 2016-04-11 | 対立遺伝子多様体の選択的低減 |
| JP2018055560A Active JP6652984B2 (ja) | 2010-02-08 | 2018-03-23 | 対立遺伝子多様体の選択的低減 |
Country Status (9)
| Country | Link |
|---|---|
| US (5) | US8957040B2 (https=) |
| EP (3) | EP3561060A1 (https=) |
| JP (4) | JP6006120B2 (https=) |
| AU (3) | AU2011213562B2 (https=) |
| CA (1) | CA2789005A1 (https=) |
| DK (1) | DK2534248T3 (https=) |
| ES (1) | ES2733708T3 (https=) |
| IL (2) | IL221272A (https=) |
| WO (1) | WO2011097643A1 (https=) |
Families Citing this family (68)
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| CA2767253A1 (en) | 2009-07-06 | 2011-01-13 | Ontorii, Inc. | Novel nucleic acid prodrugs and methods of use thereof |
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| US10017764B2 (en) | 2011-02-08 | 2018-07-10 | Ionis Pharmaceuticals, Inc. | Oligomeric compounds comprising bicyclic nucleotides and uses thereof |
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| EA202092001A1 (ru) | 2018-03-27 | 2021-01-29 | ПиТиСи ТЕРАПЬЮТИКС, ИНК. | Соединения для лечения болезни гентингтона |
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| WO2020033899A1 (en) | 2018-08-10 | 2020-02-13 | University Of Massachusetts | Modified oligonucleotides targeting snps |
| JP7627042B2 (ja) | 2018-08-23 | 2025-02-05 | ユニバーシティー オブ マサチューセッツ | O-メチルリッチ完全安定化オリゴヌクレオチド |
| CN113614232A (zh) | 2019-01-18 | 2021-11-05 | 马萨诸塞大学 | 动态药代动力学修饰锚 |
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| US12365894B2 (en) | 2019-09-16 | 2025-07-22 | University Of Massachusetts | Branched lipid conjugates of siRNA for specific tissue delivery |
| TW202131920A (zh) | 2019-11-01 | 2021-09-01 | 瑞士商諾華公司 | 剪接調節子用於減慢杭丁頓氏舞蹈症進展的治療之用途 |
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2011
- 2011-02-08 WO PCT/US2011/024103 patent/WO2011097643A1/en not_active Ceased
- 2011-02-08 EP EP19164928.4A patent/EP3561060A1/en active Pending
- 2011-02-08 ES ES17206749T patent/ES2733708T3/es active Active
- 2011-02-08 DK DK11740542.3T patent/DK2534248T3/en active
- 2011-02-08 US US13/577,616 patent/US8957040B2/en active Active
- 2011-02-08 EP EP11740542.3A patent/EP2534248B1/en active Active
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- 2011-02-08 EP EP17206749.8A patent/EP3321361B1/en not_active Revoked
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2012
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2014
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2016
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2017
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2018
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2020
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2022
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2024
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