JP2020039346A5 - - Google Patents

Download PDF

Info

Publication number
JP2020039346A5
JP2020039346A5 JP2019205184A JP2019205184A JP2020039346A5 JP 2020039346 A5 JP2020039346 A5 JP 2020039346A5 JP 2019205184 A JP2019205184 A JP 2019205184A JP 2019205184 A JP2019205184 A JP 2019205184A JP 2020039346 A5 JP2020039346 A5 JP 2020039346A5
Authority
JP
Japan
Prior art keywords
sequencing
sequence
analyzing
polynucleotide
adapter sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2019205184A
Other languages
English (en)
Japanese (ja)
Other versions
JP2020039346A (ja
JP6977014B2 (ja
Filing date
Publication date
Priority claimed from JP2016515024A external-priority patent/JP6618894B2/ja
Application filed filed Critical
Publication of JP2020039346A publication Critical patent/JP2020039346A/ja
Publication of JP2020039346A5 publication Critical patent/JP2020039346A5/ja
Priority to JP2021183126A priority Critical patent/JP7504854B2/ja
Application granted granted Critical
Publication of JP6977014B2 publication Critical patent/JP6977014B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2019205184A 2013-05-23 2019-11-13 個別的エピゲノミクスのための天然クロマチンへの転移 Active JP6977014B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2021183126A JP7504854B2 (ja) 2013-05-23 2021-11-10 個別的エピゲノミクスのための天然クロマチンへの転移

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361826728P 2013-05-23 2013-05-23
US61/826,728 2013-05-23
JP2016515024A JP6618894B2 (ja) 2013-05-23 2014-05-20 個別的エピゲノミクスのための天然クロマチンへの転移

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2016515024A Division JP6618894B2 (ja) 2013-05-23 2014-05-20 個別的エピゲノミクスのための天然クロマチンへの転移

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2021183126A Division JP7504854B2 (ja) 2013-05-23 2021-11-10 個別的エピゲノミクスのための天然クロマチンへの転移

Publications (3)

Publication Number Publication Date
JP2020039346A JP2020039346A (ja) 2020-03-19
JP2020039346A5 true JP2020039346A5 (enExample) 2020-06-25
JP6977014B2 JP6977014B2 (ja) 2021-12-08

Family

ID=51934332

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2016515024A Active JP6618894B2 (ja) 2013-05-23 2014-05-20 個別的エピゲノミクスのための天然クロマチンへの転移
JP2019205184A Active JP6977014B2 (ja) 2013-05-23 2019-11-13 個別的エピゲノミクスのための天然クロマチンへの転移
JP2021183126A Active JP7504854B2 (ja) 2013-05-23 2021-11-10 個別的エピゲノミクスのための天然クロマチンへの転移

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2016515024A Active JP6618894B2 (ja) 2013-05-23 2014-05-20 個別的エピゲノミクスのための天然クロマチンへの転移

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2021183126A Active JP7504854B2 (ja) 2013-05-23 2021-11-10 個別的エピゲノミクスのための天然クロマチンへの転移

Country Status (8)

Country Link
US (12) US10059989B2 (enExample)
EP (5) EP4617376A3 (enExample)
JP (3) JP6618894B2 (enExample)
CN (2) CN111394426B (enExample)
AU (4) AU2014268710B2 (enExample)
HK (1) HK1222416A1 (enExample)
SG (1) SG11201508985VA (enExample)
WO (1) WO2014189957A2 (enExample)

Families Citing this family (235)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8835358B2 (en) 2009-12-15 2014-09-16 Cellular Research, Inc. Digital counting of individual molecules by stochastic attachment of diverse labels
US9074251B2 (en) 2011-02-10 2015-07-07 Illumina, Inc. Linking sequence reads using paired code tags
JP6017458B2 (ja) 2011-02-02 2016-11-02 ユニヴァーシティ・オブ・ワシントン・スルー・イッツ・センター・フォー・コマーシャリゼーション 大量並列連続性マッピング
US9260753B2 (en) 2011-03-24 2016-02-16 President And Fellows Of Harvard College Single cell nucleic acid detection and analysis
US9938524B2 (en) 2011-11-22 2018-04-10 Active Motif, Inc. Multiplex isolation of protein-associated nucleic acids
US10689643B2 (en) 2011-11-22 2020-06-23 Active Motif, Inc. Targeted transposition for use in epigenetic studies
US10323279B2 (en) 2012-08-14 2019-06-18 10X Genomics, Inc. Methods and systems for processing polynucleotides
US9951386B2 (en) 2014-06-26 2018-04-24 10X Genomics, Inc. Methods and systems for processing polynucleotides
US9701998B2 (en) 2012-12-14 2017-07-11 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10221442B2 (en) 2012-08-14 2019-03-05 10X Genomics, Inc. Compositions and methods for sample processing
US10752949B2 (en) 2012-08-14 2020-08-25 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10273541B2 (en) 2012-08-14 2019-04-30 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10400280B2 (en) 2012-08-14 2019-09-03 10X Genomics, Inc. Methods and systems for processing polynucleotides
US11591637B2 (en) 2012-08-14 2023-02-28 10X Genomics, Inc. Compositions and methods for sample processing
KR102090851B1 (ko) 2012-08-14 2020-03-19 10엑스 제노믹스, 인크. 마이크로캡슐 조성물 및 방법
US10876152B2 (en) 2012-09-04 2020-12-29 Guardant Health, Inc. Systems and methods to detect rare mutations and copy number variation
US20160040229A1 (en) 2013-08-16 2016-02-11 Guardant Health, Inc. Systems and methods to detect rare mutations and copy number variation
IL269097B2 (en) 2012-09-04 2024-01-01 Guardant Health Inc Systems and methods to detect rare mutations and copy number variation
US11913065B2 (en) 2012-09-04 2024-02-27 Guardent Health, Inc. Systems and methods to detect rare mutations and copy number variation
WO2014060483A1 (en) 2012-10-17 2014-04-24 Spatial Transcriptomics Ab Methods and product for optimising localised or spatial detection of gene expression in a tissue sample
CA2894694C (en) 2012-12-14 2023-04-25 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10533221B2 (en) 2012-12-14 2020-01-14 10X Genomics, Inc. Methods and systems for processing polynucleotides
US9683230B2 (en) 2013-01-09 2017-06-20 Illumina Cambridge Limited Sample preparation on a solid support
DK2954065T3 (da) 2013-02-08 2021-09-06 10X Genomics Inc Opdeling og bearbejdning af analytter og andre arter
DK3553175T3 (da) * 2013-03-13 2021-08-23 Illumina Inc Fremgangsmåde til fremstilling af et nukleinsyresekvenseringsbibliotek
EP4617376A3 (en) * 2013-05-23 2025-12-10 The Board of Trustees of the Leland Stanford Junior University Transposition into native chromatin for personal epigenomics
US20160208323A1 (en) * 2013-06-21 2016-07-21 The Broad Institute, Inc. Methods for Shearing and Tagging DNA for Chromatin Immunoprecipitation and Sequencing
US9868979B2 (en) 2013-06-25 2018-01-16 Prognosys Biosciences, Inc. Spatially encoded biological assays using a microfluidic device
US10395758B2 (en) 2013-08-30 2019-08-27 10X Genomics, Inc. Sequencing methods
US9824068B2 (en) 2013-12-16 2017-11-21 10X Genomics, Inc. Methods and apparatus for sorting data
EP3378952B1 (en) 2013-12-28 2020-02-05 Guardant Health, Inc. Methods and systems for detecting genetic variants
KR102596508B1 (ko) 2014-04-10 2023-10-30 10엑스 제노믹스, 인크. 시약을 캡슐화 및 구획화하기 위한 유체 디바이스, 시스템, 및 방법, 및 이의 응용
MX2016016904A (es) 2014-06-26 2017-03-27 10X Genomics Inc Analisis de secuencias de acidos nucleicos.
KR102531677B1 (ko) 2014-06-26 2023-05-10 10엑스 제노믹스, 인크. 개별 세포 또는 세포 개체군으로부터 핵산을 분석하는 방법
US12312640B2 (en) 2014-06-26 2025-05-27 10X Genomics, Inc. Analysis of nucleic acid sequences
US10526641B2 (en) 2014-08-01 2020-01-07 Dovetail Genomics, Llc Tagging nucleic acids for sequence assembly
AU2015331739B2 (en) 2014-10-17 2021-12-02 Illumina Cambridge Limited Contiguity preserving transposition
KR20170073667A (ko) 2014-10-29 2017-06-28 10엑스 제노믹스, 인크. 표적화 핵산 서열 분석을 위한 방법 및 조성물
US9975122B2 (en) 2014-11-05 2018-05-22 10X Genomics, Inc. Instrument systems for integrated sample processing
US10900065B2 (en) 2014-11-14 2021-01-26 University Of Washington Methods and kits for labeling cellular molecules
EP3031929A1 (en) * 2014-12-11 2016-06-15 Mdc Max-Delbrück-Centrum Für Molekulare Medizin Berlin - Buch Genome architecture mapping
AU2015364286B2 (en) 2014-12-20 2021-11-04 Arc Bio, Llc Compositions and methods for targeted depletion, enrichment, and partitioning of nucleic acids using CRISPR/Cas system proteins
KR102321863B1 (ko) 2015-01-12 2021-11-08 10엑스 제노믹스, 인크. 핵산 시퀀싱 라이브러리의 제조 방법 및 시스템 및 이를 이용하여 제조한 라이브러리
EP4286516A3 (en) 2015-02-24 2024-03-06 10X Genomics, Inc. Partition processing methods and systems
BR112017018054A2 (pt) 2015-02-24 2018-07-24 10X Genomics Inc métodos para a cobertura de sequências de ácidos nucleicos direcionadas
EP4282977B1 (en) 2015-04-10 2024-06-05 10x Genomics Sweden AB Spatially distinguished, multiplex nucleic acid analysis of biological specimens
EP3985111A1 (en) 2015-08-19 2022-04-20 Arc Bio, LLC Capture of nucleic acids using a nucleic acid-guided nuclease-based system
CN108368548A (zh) * 2015-11-09 2018-08-03 普罗格尼迪公司 用于确定dna分子的来源的方法
US11371094B2 (en) 2015-11-19 2022-06-28 10X Genomics, Inc. Systems and methods for nucleic acid processing using degenerate nucleotides
DK3882357T3 (da) 2015-12-04 2022-08-29 10X Genomics Inc Fremgangsmåder og sammensætninger til analyse af nukleinsyrer
WO2017106768A1 (en) 2015-12-17 2017-06-22 Guardant Health, Inc. Methods to determine tumor gene copy number by analysis of cell-free dna
CN105463089A (zh) * 2015-12-21 2016-04-06 同济大学 应用于斑马鱼胚胎的易接近转座酶核染色质高通量测序实验的方法
JP6735348B2 (ja) 2016-02-11 2020-08-05 10エックス ジェノミクス, インコーポレイテッド 全ゲノム配列データのデノボアセンブリのためのシステム、方法及び媒体
CN109072206A (zh) * 2016-03-10 2018-12-21 斯坦福大学托管董事会 转座酶介导的对可接近基因组的成像
ES3002715T3 (en) 2016-04-14 2025-03-07 Guardant Health Inc Methods for early detection of cancer
US11384382B2 (en) 2016-04-14 2022-07-12 Guardant Health, Inc. Methods of attaching adapters to sample nucleic acids
US11932847B2 (en) 2016-04-19 2024-03-19 Kapa Biosystems, Inc. Transposase competitor control system
WO2017197343A2 (en) 2016-05-12 2017-11-16 10X Genomics, Inc. Microfluidic on-chip filters
WO2017197338A1 (en) 2016-05-13 2017-11-16 10X Genomics, Inc. Microfluidic systems and methods of use
ES2873723T3 (es) * 2016-07-22 2021-11-03 Univ Oregon Health & Science Colecciones de genoma completo de células individuales y métodos de indexación combinatoria para prepararlas
WO2018035388A1 (en) * 2016-08-17 2018-02-22 The Broad Institute, Inc. Novel crispr enzymes and systems
US11414680B2 (en) 2016-08-30 2022-08-16 Kyushu University National University Corporation Method for inserting desired DNA fragment into site located adjacent to binding domain of DNA-binding protein
KR20240155386A (ko) 2016-09-30 2024-10-28 가던트 헬쓰, 인크. 무세포 핵산의 다중-해상도 분석 방법
US9850523B1 (en) 2016-09-30 2017-12-26 Guardant Health, Inc. Methods for multi-resolution analysis of cell-free nucleic acids
CA3043708A1 (en) * 2016-11-17 2018-05-24 Cleveland State University Chip platforms for microarray 3d bioprinting
JP2020501240A (ja) * 2016-11-18 2020-01-16 ナントミクス,エルエルシー 汎がんゲノムにおけるdnaアクセシビリティを予測するための方法及びシステム
WO2018103025A1 (zh) * 2016-12-07 2018-06-14 深圳华大智造科技有限公司 单细胞测序文库的构建方法及其应用
US10550429B2 (en) 2016-12-22 2020-02-04 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10815525B2 (en) 2016-12-22 2020-10-27 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10011872B1 (en) 2016-12-22 2018-07-03 10X Genomics, Inc. Methods and systems for processing polynucleotides
KR102747205B1 (ko) * 2016-12-29 2024-12-31 일루미나, 인코포레이티드 세포 구획 내의 생체분자에 대한 직교 접근 및 그의 태그부착을 위한 분석 시스템
JP7429338B2 (ja) 2017-01-10 2024-02-08 ジュノー セラピューティクス インコーポレイテッド 細胞療法および関連方法のエピジェネティック解析
CN117512066A (zh) 2017-01-30 2024-02-06 10X基因组学有限公司 用于基于微滴的单细胞条形编码的方法和系统
US12264411B2 (en) 2017-01-30 2025-04-01 10X Genomics, Inc. Methods and systems for analysis
US10995333B2 (en) 2017-02-06 2021-05-04 10X Genomics, Inc. Systems and methods for nucleic acid preparation
EP3583112A4 (en) * 2017-02-14 2021-04-07 Seqwell, Inc. COMPOSITIONS AND METHODS FOR THE SEQUENCING OF NUCLEIC ACIDS
JP7197567B2 (ja) 2017-05-05 2022-12-27 スキピオ バイオサイエンス ハイドロゲル中の個別の生物学的単位を捕捉およびバーコード付与するための方法
US10914729B2 (en) 2017-05-22 2021-02-09 The Trustees Of Princeton University Methods for detecting protein binding sequences and tagging nucleic acids
EP3445876B1 (en) 2017-05-26 2023-07-05 10X Genomics, Inc. Single cell analysis of transposase accessible chromatin
US10400235B2 (en) 2017-05-26 2019-09-03 10X Genomics, Inc. Single cell analysis of transposase accessible chromatin
WO2018226546A1 (en) 2017-06-05 2018-12-13 10X Genomics, Inc. Gaskets for the distribution of pressures in a microfluidic system
US11180804B2 (en) 2017-07-25 2021-11-23 Massachusetts Institute Of Technology In situ ATAC sequencing
US20200347441A1 (en) * 2017-08-30 2020-11-05 Kapa Biosystems, Inc. Transposase compositions, methods of making, and methods of screening
JP7241069B2 (ja) * 2017-09-25 2023-03-16 フレッド ハッチンソン キャンサー センター 高効率標的in situゲノムワイドプロファイリング
US10837047B2 (en) 2017-10-04 2020-11-17 10X Genomics, Inc. Compositions, methods, and systems for bead formation using improved polymers
WO2019071054A1 (en) 2017-10-04 2019-04-11 The Broad Institute, Inc. METHODS AND COMPOSITIONS FOR MODIFYING THE FUNCTION AND STRUCTURE OF BUCKLES AND / OR CHROMATIN DOMAINS
US10590244B2 (en) 2017-10-04 2020-03-17 10X Genomics, Inc. Compositions, methods, and systems for bead formation using improved polymers
WO2019084055A1 (en) 2017-10-23 2019-05-02 Massachusetts Institute Of Technology CLASSIFICATION OF GENETIC VARIATION FROM UNICELLULAR TRANSCRIPTOMS
WO2019084043A1 (en) 2017-10-26 2019-05-02 10X Genomics, Inc. METHODS AND SYSTEMS FOR NUCLEIC ACID PREPARATION AND CHROMATIN ANALYSIS
EP4241882B1 (en) 2017-10-27 2025-04-30 10X Genomics, Inc. Methods for sample preparation and analysis
CN118186055A (zh) 2017-11-02 2024-06-14 生物辐射实验室股份有限公司 基于转座酶的基因组分析
SG11201913654QA (en) 2017-11-15 2020-01-30 10X Genomics Inc Functionalized gel beads
US10829815B2 (en) 2017-11-17 2020-11-10 10X Genomics, Inc. Methods and systems for associating physical and genetic properties of biological particles
WO2019108851A1 (en) 2017-11-30 2019-06-06 10X Genomics, Inc. Systems and methods for nucleic acid preparation and analysis
US11332736B2 (en) 2017-12-07 2022-05-17 The Broad Institute, Inc. Methods and compositions for multiplexing single cell and single nuclei sequencing
CN118818037A (zh) 2017-12-12 2024-10-22 10X基因组学有限公司 用于单细胞处理的系统和方法
EP3728631A1 (en) 2017-12-22 2020-10-28 10X Genomics, Inc. Systems and methods for processing nucleic acid molecules from one or more cells
CN108085379A (zh) * 2017-12-28 2018-05-29 上海嘉因生物科技有限公司 应用于组织样本中染色体开放结合区域定位的ATAC-seq方法
AU2019214956B2 (en) 2018-01-31 2025-06-26 Dovetail Genomics, Llc Sample prep for DNA linkage recovery
WO2019152108A1 (en) 2018-02-05 2019-08-08 The Board Of Trustees Of The Leland Stanford Junior University Systems and methods for multiplexed measurements in single and ensemble cells
CN108360074B (zh) * 2018-02-11 2022-01-18 奥明(杭州)基因科技有限公司 一种组织淋巴细胞转座酶可接近性染色质分析的建库方法
CN112005115A (zh) 2018-02-12 2020-11-27 10X基因组学有限公司 表征来自单个细胞或细胞群体的多种分析物的方法
KR102773714B1 (ko) 2018-02-13 2025-02-27 일루미나, 인코포레이티드 하이드로겔 비드를 사용한 dna 서열분석
US11639928B2 (en) 2018-02-22 2023-05-02 10X Genomics, Inc. Methods and systems for characterizing analytes from individual cells or cell populations
WO2019169028A1 (en) 2018-02-28 2019-09-06 10X Genomics, Inc. Transcriptome sequencing through random ligation
US11841371B2 (en) 2018-03-13 2023-12-12 The Broad Institute, Inc. Proteomics and spatial patterning using antenna networks
WO2019195166A1 (en) 2018-04-06 2019-10-10 10X Genomics, Inc. Systems and methods for quality control in single cell processing
JP7511344B2 (ja) 2018-04-20 2024-07-05 イルミナ インコーポレイテッド 単一細胞を封入する方法、封入された細胞およびその使用
US11957695B2 (en) 2018-04-26 2024-04-16 The Broad Institute, Inc. Methods and compositions targeting glucocorticoid signaling for modulating immune responses
WO2019213294A1 (en) 2018-05-03 2019-11-07 Becton, Dickinson And Company High throughput multiomics sample analysis
WO2019213660A2 (en) 2018-05-04 2019-11-07 The Broad Institute, Inc. Compositions and methods for modulating cgrp signaling to regulate innate lymphoid cell inflammatory responses
WO2019217758A1 (en) 2018-05-10 2019-11-14 10X Genomics, Inc. Methods and systems for molecular library generation
CN119955902A (zh) 2018-05-17 2025-05-09 伊鲁米纳公司 具有减少的扩增偏倚的高通量单细胞测序
US11414701B2 (en) 2018-05-24 2022-08-16 The Broad Institute, Inc. Multimodal readouts for quantifying and sequencing nucleic acids in single cells
US11932899B2 (en) 2018-06-07 2024-03-19 10X Genomics, Inc. Methods and systems for characterizing nucleic acid molecules
US12012633B2 (en) 2018-06-11 2024-06-18 The Broad Institute, Inc. Lineage tracing using mitochondrial genome mutations and single cell genomics
US11703427B2 (en) 2018-06-25 2023-07-18 10X Genomics, Inc. Methods and systems for cell and bead processing
US12188014B1 (en) 2018-07-25 2025-01-07 10X Genomics, Inc. Compositions and methods for nucleic acid processing using blocking agents
US20200032335A1 (en) 2018-07-27 2020-01-30 10X Genomics, Inc. Systems and methods for metabolome analysis
US12163179B2 (en) 2018-08-03 2024-12-10 10X Gemomics, Inc. Methods and systems to minimize barcode exchange
US20210277454A1 (en) * 2018-08-14 2021-09-09 Trustees Of Dartmouth College Atac-array for prediction of disease-free survival in pancreatic cancer
EP4249651B1 (en) 2018-08-20 2025-01-29 Bio-Rad Laboratories, Inc. Nucleotide sequence generation by barcode bead-colocalization in partitions
WO2020041148A1 (en) 2018-08-20 2020-02-27 10X Genomics, Inc. Methods and systems for detection of protein-dna interactions using proximity ligation
US12065688B2 (en) 2018-08-20 2024-08-20 10X Genomics, Inc. Compositions and methods for cellular processing
US11519033B2 (en) 2018-08-28 2022-12-06 10X Genomics, Inc. Method for transposase-mediated spatial tagging and analyzing genomic DNA in a biological sample
CN113227388A (zh) 2018-10-01 2021-08-06 龙沙有限公司 具有可预测和稳定的转基因表达的ssi细胞及形成方法
WO2020077236A1 (en) 2018-10-12 2020-04-16 The Broad Institute, Inc. Method for extracting nuclei or whole cells from formalin-fixed paraffin-embedded tissues
SG11202102703VA (en) 2018-10-26 2021-04-29 Illumina Inc Modulating polymer beads for dna processing
US12402610B2 (en) 2018-11-09 2025-09-02 The Broad Institute, Inc. Methods and compositions for modulating innate lymphoid cell pathogenic effectors
KR20210098432A (ko) 2018-11-30 2021-08-10 일루미나, 인코포레이티드 단일 검정을 이용한 다수의 분석물의 분석
US11459607B1 (en) 2018-12-10 2022-10-04 10X Genomics, Inc. Systems and methods for processing-nucleic acid molecules from a single cell using sequential co-partitioning and composite barcodes
US12529094B2 (en) 2018-12-10 2026-01-20 10X Genomics, Inc. Imaging system hardware
WO2020123311A2 (en) 2018-12-10 2020-06-18 10X Genomics, Inc. Resolving spatial arrays using deconvolution
SG11202102424QA (en) 2018-12-17 2021-04-29 Illumina Inc Methods and means for preparing a library for sequencing
US11657897B2 (en) 2018-12-31 2023-05-23 Nvidia Corporation Denoising ATAC-seq data with deep learning
US11926867B2 (en) 2019-01-06 2024-03-12 10X Genomics, Inc. Generating capture probes for spatial analysis
SG11202107418SA (en) 2019-01-06 2021-08-30 10X Genomics Inc Methods and systems for enrichment of barcodes
US11649485B2 (en) 2019-01-06 2023-05-16 10X Genomics, Inc. Generating capture probes for spatial analysis
US12169198B2 (en) 2019-01-08 2024-12-17 10X Genomics, Inc. Systems and methods for sample analysis
US11845983B1 (en) 2019-01-09 2023-12-19 10X Genomics, Inc. Methods and systems for multiplexing of droplet based assays
US12529092B2 (en) 2019-01-28 2026-01-20 The Broad Institute, Inc. In-situ spatial transcriptomics
EP3918089B1 (en) 2019-01-31 2025-01-15 Guardant Health, Inc. Method for isolating and sequencing cell-free dna
JP2022521708A (ja) * 2019-02-11 2022-04-12 エピサイファー,インコーポレイテッド ロングリードシーケンシングを使用するクロマチンマッピングアッセイおよびキット
WO2020167866A1 (en) 2019-02-12 2020-08-20 10X Genomics, Inc. Systems and methods for transposon loading
WO2020167862A1 (en) 2019-02-12 2020-08-20 10X Genomics, Inc. Systems and methods for transfer of reagents between droplets
US11851683B1 (en) 2019-02-12 2023-12-26 10X Genomics, Inc. Methods and systems for selective analysis of cellular samples
US12275993B2 (en) 2019-02-12 2025-04-15 10X Genomics, Inc. Analysis of nucleic acid sequences
US12305239B2 (en) 2019-02-12 2025-05-20 10X Genomics, Inc. Analysis of nucleic acid sequences
WO2020168013A1 (en) 2019-02-12 2020-08-20 10X Genomics, Inc. Methods for processing nucleic acid molecules
US11467153B2 (en) 2019-02-12 2022-10-11 10X Genomics, Inc. Methods for processing nucleic acid molecules
US11655499B1 (en) 2019-02-25 2023-05-23 10X Genomics, Inc. Detection of sequence elements in nucleic acid molecules
WO2020180778A1 (en) 2019-03-01 2020-09-10 Illumina, Inc. High-throughput single-nuclei and single-cell libraries and methods of making and of using
WO2020185791A1 (en) 2019-03-11 2020-09-17 10X Genomics, Inc. Systems and methods for processing optically tagged beads
US20220154282A1 (en) 2019-03-12 2022-05-19 The Broad Institute, Inc. Detection means, compositions and methods for modulating synovial sarcoma cells
WO2020186235A1 (en) 2019-03-14 2020-09-17 The Broad Institute, Inc. Compositions and methods for modulating cgrp signaling to regulate intestinal innate lymphoid cells
WO2020191069A1 (en) 2019-03-18 2020-09-24 The Broad Institute, Inc. Modulation of type 2 immunity by targeting clec-2 signaling
WO2020191079A1 (en) 2019-03-18 2020-09-24 The Broad Institute, Inc. Compositions and methods for modulating metabolic regulators of t cell pathogenicity
CN111755071B (zh) * 2019-03-29 2023-04-21 中国科学技术大学 基于峰聚类的单细胞染色质可及性测序数据分析方法和系统
EP3947719A4 (en) * 2019-03-29 2023-01-04 The Board of Trustees of the Leland Stanford Junior University TREATMENT METHODS BASED ON ANTHRACYCLINE RESPONSE
US20220170110A1 (en) * 2019-04-05 2022-06-02 Korea Advanced Institute Of Science And Technology Cancer diagnostic marker using transposase-accessible chromatin sequencing information about individual, and use thereof
KR102192455B1 (ko) * 2019-04-05 2020-12-17 한국과학기술원 개인의 전이효소-접근가능한 염색질 시퀀싱 정보를 이용한 암 진단 마커 및 이의 용도
WO2020210802A1 (en) * 2019-04-11 2020-10-15 University Of Virginia Patent Foundation Tagmentation to open up circles of dna and detect extrachromosomal circles of dna for diagnosis
WO2020243579A1 (en) 2019-05-30 2020-12-03 10X Genomics, Inc. Methods of detecting spatial heterogeneity of a biological sample
CN112176041A (zh) * 2019-07-01 2021-01-05 深圳华大生命科学研究院 一种表观遗传修饰的检测方法、试剂和应用
US20220282333A1 (en) 2019-08-13 2022-09-08 The General Hospital Corporation Methods for predicting outcomes of checkpoint inhibition and treatment thereof
US12421557B2 (en) 2019-08-16 2025-09-23 The Broad Institute, Inc. Methods for predicting outcomes and treating colorectal cancer using a cell atlas
US12235262B1 (en) 2019-09-09 2025-02-25 10X Genomics, Inc. Methods and systems for single cell protein analysis
US12264367B2 (en) 2019-09-19 2025-04-01 The Broad Institute, Inc. Methods of in vivo evaluation of gene function
US11793787B2 (en) 2019-10-07 2023-10-24 The Broad Institute, Inc. Methods and compositions for enhancing anti-tumor immunity by targeting steroidogenesis
EP4025711A2 (en) 2019-11-08 2022-07-13 10X Genomics, Inc. Enhancing specificity of analyte binding
US12241830B2 (en) 2019-12-06 2025-03-04 Broad Institute, Inc. Living biosensors
EP3927824A2 (en) 2019-12-19 2021-12-29 Illumina, Inc. High-throughput single-cell libraries and methods of making and of using
WO2021127610A1 (en) 2019-12-20 2021-06-24 EDWARD Via COLLEGE OF OSTEOPATHIC MEDICINE Cancer signatures, methods of generating cancer signatures, and uses thereof
DK3891300T3 (da) 2019-12-23 2023-05-22 10X Genomics Inc Fremgangsmåder til rumlig analyse ved anvendelse af rna-template-ligering
US12241890B2 (en) 2019-12-23 2025-03-04 10X Genomics, Inc. Methods for generating barcoded nucleic acid molecules using fixed cells
CN115135984B (zh) 2019-12-23 2025-12-23 10X基因组学有限公司 可逆固定试剂及其使用方法
WO2021128034A1 (zh) * 2019-12-25 2021-07-01 苏州绘真生物科技有限公司 高通量单细胞染色质可及性的测序方法
US12365942B2 (en) 2020-01-13 2025-07-22 10X Genomics, Inc. Methods of decreasing background on a spatial array
CN111172257A (zh) * 2020-01-16 2020-05-19 南方科技大学 一种带编码的凝胶微粒及其制备方法和应用
US12405264B2 (en) 2020-01-17 2025-09-02 10X Genomics, Inc. Electrophoretic system and method for analyte capture
US11702693B2 (en) 2020-01-21 2023-07-18 10X Genomics, Inc. Methods for printing cells and generating arrays of barcoded cells
US11732299B2 (en) 2020-01-21 2023-08-22 10X Genomics, Inc. Spatial assays with perturbed cells
US12165747B2 (en) 2020-01-23 2024-12-10 The Broad Institute, Inc. Molecular spatial mapping of metastatic tumor microenvironment
US20210230681A1 (en) 2020-01-24 2021-07-29 10X Genomics, Inc. Methods for spatial analysis using proximity ligation
US12076701B2 (en) 2020-01-31 2024-09-03 10X Genomics, Inc. Capturing oligonucleotides in spatial transcriptomics
US12110541B2 (en) 2020-02-03 2024-10-08 10X Genomics, Inc. Methods for preparing high-resolution spatial arrays
US11898205B2 (en) 2020-02-03 2024-02-13 10X Genomics, Inc. Increasing capture efficiency of spatial assays
US12112833B2 (en) 2020-02-04 2024-10-08 10X Genomics, Inc. Systems and methods for index hopping filtering
US11732300B2 (en) 2020-02-05 2023-08-22 10X Genomics, Inc. Increasing efficiency of spatial analysis in a biological sample
US12129516B2 (en) 2020-02-07 2024-10-29 10X Genomics, Inc. Quantitative and automated permeabilization performance evaluation for spatial transcriptomics
WO2021163611A1 (en) 2020-02-13 2021-08-19 10X Genomics, Inc. Methods for characterizing cells using gene expression and chromatin accessibility
US12281357B1 (en) 2020-02-14 2025-04-22 10X Genomics, Inc. In situ spatial barcoding
US11891654B2 (en) 2020-02-24 2024-02-06 10X Genomics, Inc. Methods of making gene expression libraries
ES3014967T3 (en) 2020-04-22 2025-04-28 10X Genomics Inc Methods for spatial analysis using targeted rna depletion
US11851700B1 (en) 2020-05-13 2023-12-26 10X Genomics, Inc. Methods, kits, and compositions for processing extracellular molecules
EP4414459B1 (en) 2020-05-22 2025-09-03 10X Genomics, Inc. Simultaneous spatio-temporal measurement of gene expression and cellular activity
EP4153776B1 (en) 2020-05-22 2025-03-05 10X Genomics, Inc. Spatial analysis to detect sequence variants
WO2021242834A1 (en) 2020-05-26 2021-12-02 10X Genomics, Inc. Method for resetting an array
US12031177B1 (en) 2020-06-04 2024-07-09 10X Genomics, Inc. Methods of enhancing spatial resolution of transcripts
EP4421186B1 (en) 2020-06-08 2025-08-13 10X Genomics, Inc. Methods of determining a surgical margin and methods of use thereof
WO2021252591A1 (en) 2020-06-10 2021-12-16 10X Genomics, Inc. Methods for determining a location of an analyte in a biological sample
EP4450639B1 (en) 2020-06-25 2025-10-15 10X Genomics, Inc. Spatial analysis of dna methylation
US12168801B1 (en) 2020-07-02 2024-12-17 10X Genomics, Inc. Hybrid/capture probe designs for full-length cDNA
US11761038B1 (en) 2020-07-06 2023-09-19 10X Genomics, Inc. Methods for identifying a location of an RNA in a biological sample
US11981960B1 (en) 2020-07-06 2024-05-14 10X Genomics, Inc. Spatial analysis utilizing degradable hydrogels
US12209280B1 (en) 2020-07-06 2025-01-28 10X Genomics, Inc. Methods of identifying abundance and location of an analyte in a biological sample using second strand synthesis
EP4192486A4 (en) 2020-08-07 2024-05-01 The Broad Institute, Inc. THERAPEUTIC TARGETING OF PHOSPHATE DISREGULATION IN CANCER VIA THE XPR1 PROTEIN COMPLEX: KIDINS220
US11981958B1 (en) 2020-08-20 2024-05-14 10X Genomics, Inc. Methods for spatial analysis using DNA capture
WO2022056704A1 (zh) * 2020-09-16 2022-03-24 深圳华大生命科学研究院 多维度解析细胞表观基因组学的方法
US11926822B1 (en) 2020-09-23 2024-03-12 10X Genomics, Inc. Three-dimensional spatial analysis
US12480158B1 (en) 2020-11-05 2025-11-25 10X Genomics, Inc. Methods and systems for processing polynucleotides
US12084715B1 (en) 2020-11-05 2024-09-10 10X Genomics, Inc. Methods and systems for reducing artifactual antisense products
US11827935B1 (en) 2020-11-19 2023-11-28 10X Genomics, Inc. Methods for spatial analysis using rolling circle amplification and detection probes
WO2022140028A1 (en) 2020-12-21 2022-06-30 10X Genomics, Inc. Methods, compositions, and systems for capturing probes and/or barcodes
JP2024502028A (ja) * 2020-12-30 2024-01-17 ダブテイル ゲノミクス エルエルシー 配列決定ライブラリー調製のための方法および組成物
US12398262B1 (en) 2021-01-22 2025-08-26 10X Genomics, Inc. Triblock copolymer-based cell stabilization and fixation system and methods of use thereof
EP4298244A1 (en) 2021-02-23 2024-01-03 10X Genomics, Inc. Probe-based analysis of nucleic acids and proteins
EP4305196B1 (en) 2021-04-14 2025-04-02 10X Genomics, Inc. Methods of measuring mislocalization of an analyte
WO2022236054A1 (en) 2021-05-06 2022-11-10 10X Genomics, Inc. Methods for increasing resolution of spatial analysis
EP4582555A3 (en) 2021-06-03 2025-10-22 10X Genomics, Inc. Methods, compositions, kits, and systems for enhancing analyte capture for spatial analysis
EP4196605B1 (en) 2021-09-01 2024-12-04 10X Genomics, Inc. Methods for blocking a capture probe on a spatial array
CN113774136A (zh) * 2021-09-17 2021-12-10 杭州瀚因生命科技有限公司 一种基因组特定区域染色质开放性定量检测方法
CN113774052A (zh) * 2021-09-30 2021-12-10 首都医科大学附属北京安贞医院 mtDNA的提取和建库试剂
GB202114206D0 (en) 2021-10-04 2021-11-17 Genome Res Ltd Novel method
WO2023086880A1 (en) 2021-11-10 2023-05-19 10X Genomics, Inc. Methods, compositions, and kits for determining the location of an analyte in a biological sample
WO2023102118A2 (en) 2021-12-01 2023-06-08 10X Genomics, Inc. Methods, compositions, and systems for improved in situ detection of analytes and spatial analysis
EP4272764A1 (en) 2022-05-03 2023-11-08 Scipio Bioscience Method of complexing biological units with particles
WO2024076728A1 (en) 2022-10-06 2024-04-11 Dana-Farber Cancer Institute, Inc. Cyclic nucleotides and uses thereof
WO2024086673A2 (en) * 2022-10-18 2024-04-25 Moonwalk Biosciences, Inc. Controlled reprogramming of a cell
EP4482979B1 (en) 2022-11-09 2025-10-01 10X Genomics, Inc. Methods, compositions, and kits for determining the location of multiple analytes in a biological sample
WO2024112806A1 (en) * 2022-11-21 2024-05-30 Moonwalk Biosciences, Inc. Generation and use of epigenetic maps for drug discovery
WO2025072383A1 (en) 2023-09-25 2025-04-03 The Broad Institute, Inc. Viral open reading frames, uses thereof, and methods of detecting the same
WO2025215010A1 (en) * 2024-04-08 2025-10-16 Belgian Volition Srl Method for investigating neutrophils
WO2025245269A1 (en) 2024-05-21 2025-11-27 The Broad Institute, Inc. Screening method to identify mechanisms of cancer resistance and synthetic lethality in resistant cancer cells
WO2026024826A1 (en) * 2024-07-25 2026-01-29 Episteme Prognostics, Inc. Combination methods for profiling genetic mutations and chromatin accessibility

Family Cites Families (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5137829A (en) 1987-10-05 1992-08-11 Washington University DNA transposon TN5SEQ1
US5981179A (en) 1991-11-14 1999-11-09 Digene Diagnostics, Inc. Continuous amplification reaction
US5840865A (en) 1992-09-14 1998-11-24 Institute Of Molecular Biology And Biotechnology/Forth Eukaryotic transposable element
US5604097A (en) 1994-10-13 1997-02-18 Spectragen, Inc. Methods for sorting polynucleotides using oligonucleotide tags
US6458530B1 (en) 1996-04-04 2002-10-01 Affymetrix Inc. Selecting tag nucleic acids
US5965443A (en) 1996-09-09 1999-10-12 Wisconsin Alumni Research Foundation System for in vitro transposition
FI103809B1 (fi) 1997-07-14 1999-09-30 Finnzymes Oy In vitro -menetelmä templaattien tuottamiseksi DNA-sekventointia varten
US5948902A (en) 1997-11-20 1999-09-07 South Alabama Medical Science Foundation Antisense oligonucleotides to human serine/threonine protein phosphatase genes
AU3196099A (en) 1998-03-27 1999-10-18 President And Fellows Of Harvard College Systematic identification of essential genes by (in vitro) transposon mutagenesis
US6022716A (en) 1998-04-10 2000-02-08 Genset Sa High throughput DNA sequencing vector
US6159736A (en) 1998-09-23 2000-12-12 Wisconsin Alumni Research Foundation Method for making insertional mutations using a Tn5 synaptic complex
US6291243B1 (en) 1999-04-28 2001-09-18 The Board Of Trustees Of The Leland Stanford Jr. University P element derived vector and methods for its use
WO2001030965A2 (en) 1999-10-28 2001-05-03 The Board Of Trustees Of The Leland Stanford Junior University Methods of in vivo gene transfer using a sleeping beauty transposon system
CA2332186A1 (en) 2001-02-08 2002-08-08 Her Majesty In Right Of Canada As Represented By The Minister Of Agricul Ture And Agri-Food Canada Replicative in vivo gene targeting
US7138267B1 (en) 2001-04-04 2006-11-21 Epicentre Technologies Corporation Methods and compositions for amplifying DNA clone copy number
EP1427746A4 (en) * 2001-07-20 2005-09-28 California Inst Of Techn SYSTEMS FOR THE EXPRESSION OF PROTEINS AND NUCLEIC ACIDS
EP1465993B1 (en) * 2002-01-09 2009-09-23 Minos Biosystems Limited Inducible transposition in transgenic organism using transposon vector
KR100459870B1 (ko) 2002-02-22 2004-12-04 한국과학기술원 트랜스포존과 Cre/loxP 부위 특이적 재조합 방법을 이용하는 염색체의 특정부위가 제거된 미생물 변이주 제조방법
US7527966B2 (en) 2002-06-26 2009-05-05 Transgenrx, Inc. Gene regulation in transgenic animals using a transposon-based vector
US6979713B2 (en) 2002-11-25 2005-12-27 3M Innovative Properties Company Curable compositions and abrasive articles therefrom
EP1594973B1 (en) 2003-02-10 2011-12-07 Max-Delbrück-Centrum für Molekulare Medizin (MDC) Transposon-based targeting system
GB2403475B (en) 2003-07-01 2008-02-06 Oxitec Ltd Stable integrands
US8071364B2 (en) 2003-12-24 2011-12-06 Transgenrx, Inc. Gene therapy using transposon-based vectors
US20050233340A1 (en) 2004-04-20 2005-10-20 Barrett Michael T Methods and compositions for assessing CpG methylation
US7608434B2 (en) 2004-08-04 2009-10-27 Wisconsin Alumni Research Foundation Mutated Tn5 transposase proteins and the use thereof
EP2392657B1 (en) 2005-07-05 2013-09-25 The Chemo-Sero-Therapeutic Research Institute Modified transposon vector and its use
GB0603251D0 (en) 2006-02-17 2006-03-29 Isis Innovation DNA conformation
JP5320546B2 (ja) 2006-12-13 2013-10-23 国立大学法人名古屋大学 Tol1因子のトランスポザーゼ及びそれを用いたDNA導入システム
GB0810051D0 (en) 2008-06-02 2008-07-09 Oxford Biodynamics Ltd Method of diagnosis
US9080211B2 (en) 2008-10-24 2015-07-14 Epicentre Technologies Corporation Transposon end compositions and methods for modifying nucleic acids
DK2787565T3 (en) 2008-10-24 2015-10-12 Epict Technologies Corp Transposon-end COMPOSITIONS AND METHODS TO MODIFY nucleic acids
SG171916A1 (en) * 2008-12-02 2011-07-28 Bio Rad Laboratories Chromatin structure detection
US8514860B2 (en) * 2010-02-23 2013-08-20 Broadcom Corporation Systems and methods for implementing a high throughput mode for a MoCA device
US20110306042A1 (en) * 2010-06-04 2011-12-15 Bio-Rad Laboratories, Inc. Determination of chromatin conformation
US9074251B2 (en) 2011-02-10 2015-07-07 Illumina, Inc. Linking sequence reads using paired code tags
US8829171B2 (en) 2011-02-10 2014-09-09 Illumina, Inc. Linking sequence reads using paired code tags
ES2762866T3 (es) 2011-01-28 2020-05-26 Illumina Inc Reemplazo de nucleótidos por bibliotecas doblemente etiquetadas y direccionales
JP6017458B2 (ja) 2011-02-02 2016-11-02 ユニヴァーシティ・オブ・ワシントン・スルー・イッツ・センター・フォー・コマーシャリゼーション 大量並列連続性マッピング
US9005935B2 (en) 2011-05-23 2015-04-14 Agilent Technologies, Inc. Methods and compositions for DNA fragmentation and tagging by transposases
US9150916B2 (en) 2011-06-24 2015-10-06 Beat Christen Compositions and methods for identifying the essential genome of an organism
US8927218B2 (en) 2011-06-27 2015-01-06 Flir Systems, Inc. Methods and compositions for segregating target nucleic acid from mixed nucleic acid samples
EP2739394A2 (en) 2011-08-04 2014-06-11 Sage Science, Inc. Microfluidic systems and methods for processing fluids
US10689643B2 (en) 2011-11-22 2020-06-23 Active Motif, Inc. Targeted transposition for use in epigenetic studies
WO2014190214A1 (en) 2013-05-22 2014-11-27 Active Motif, Inc. Targeted transposition for use in epigenetic studies
US9938524B2 (en) * 2011-11-22 2018-04-10 Active Motif, Inc. Multiplex isolation of protein-associated nucleic acids
NO2694769T3 (enExample) 2012-03-06 2018-03-03
US20150284768A1 (en) 2012-05-29 2015-10-08 The Johns Hopkins University Eukaryotic transposase mutants and transposon end compositions for modifying nucleic acids and methods for production and use in the generation of sequencing libraries
EP2898096B1 (en) 2012-09-21 2024-02-14 The Broad Institute, Inc. Methods for labeling of rnas
US9683230B2 (en) 2013-01-09 2017-06-20 Illumina Cambridge Limited Sample preparation on a solid support
DK3553175T3 (da) 2013-03-13 2021-08-23 Illumina Inc Fremgangsmåde til fremstilling af et nukleinsyresekvenseringsbibliotek
US9328382B2 (en) 2013-03-15 2016-05-03 Complete Genomics, Inc. Multiple tagging of individual long DNA fragments
EP2971097B1 (en) 2013-03-15 2018-08-01 Verinata Health, Inc Generating cell-free dna libraries directly from blood
EP4617376A3 (en) * 2013-05-23 2025-12-10 The Board of Trustees of the Leland Stanford Junior University Transposition into native chromatin for personal epigenomics
US20160122753A1 (en) 2013-06-12 2016-05-05 Tarjei Mikkelsen High-throughput rna-seq
US20160208323A1 (en) 2013-06-21 2016-07-21 The Broad Institute, Inc. Methods for Shearing and Tagging DNA for Chromatin Immunoprecipitation and Sequencing
EP3019618B1 (en) 2013-07-12 2018-10-31 University of South Alabama Minimal piggybac vectors for genome integration
EP3102691B1 (en) 2014-02-03 2019-09-11 Thermo Fisher Scientific Baltics UAB Method for controlled dna fragmentation
JP6996844B2 (ja) 2014-02-27 2022-02-03 ジャンプコード ゲノミクス,インク. 体細胞可動要素の分析のための方法、およびその使用
WO2015179706A1 (en) 2014-05-23 2015-11-26 Fluidigm Corporation Haploidome determination by digitized transposons
US10017759B2 (en) 2014-06-26 2018-07-10 Illumina, Inc. Library preparation of tagged nucleic acid
US20180087050A1 (en) 2015-05-27 2018-03-29 Jianbiao Zheng Methods of inserting molecular barcodes
EP3314018A1 (en) 2015-06-24 2018-05-02 Oxford Biodynamics Limited Detection processes using sites of chromosome interaction
AU2016297510B2 (en) 2015-07-17 2021-09-09 President And Fellows Of Harvard College Methods of amplifying nucleic acid sequences
EP3334841B1 (en) 2015-08-12 2019-10-30 CeMM - Forschungszentrum für Molekulare Medizin GmbH Methods for studying nucleic acids

Similar Documents

Publication Publication Date Title
JP2020039346A5 (enExample)
Wang et al. High-resolution genome-wide functional dissection of transcriptional regulatory regions and nucleotides in human
Sanz et al. RiboTag: Ribosomal tagging strategy to analyze cell‐type‐specific mRNA expression in vivo
Weber et al. Plant enhancers: a call for discovery
Denker et al. The second decade of 3C technologies: detailed insights into nuclear organization
Schmidt et al. ChIP-seq: using high-throughput sequencing to discover protein–DNA interactions
Bouwman et al. Genome-wide detection of DNA double-strand breaks by in-suspension BLISS
Kadakkuzha et al. Genomics and proteomics in solving brain complexity
Awasthi et al. An overview of circular RNAs
Goh et al. Chromatin interaction analysis with paired-end tag sequencing (ChIA-PET) for mapping chromatin interactions and understanding transcription regulation
CN110669834A (zh) 一种基于转录组序列开发多态性ssr标记的方法
Farzad et al. Spatially resolved epigenome sequencing via Tn5 transposition and deterministic DNA barcoding in tissue
Lusvarghi et al. RNA secondary structure prediction using high-throughput SHAPE
Wakimoto et al. Isolation of Single‐Stranded DNA
Geisenberger et al. A cost-effective and scalable approach for DNA extraction from FFPE tissues
Chiu Next-generation sequencing and sequence data analysis
Matteau et al. Precise identification of DNA-binding proteins genomic location by exonuclease coupled chromatin immunoprecipitation (ChIP-exo)
Yadav et al. Chromatin immunoprecipitation and library preparation: A powerful tool to unravel the epigenome
Yang et al. Chromatin immunoprecipitation and an open chromatin assay in zebrafish erythrocytes
CN107794257A (zh) 一种dna大片段文库的构建方法及其应用
Hou et al. Best practices for ChIP-seq and its data analysis
Haas et al. Targeted next-generation sequencing: the clinician’s stethoscope for genetic disorders
Fish et al. Transcriptome Analysis at the Single‐Cell Level Using SMART Technology
Mueller et al. Sequencing of mRNA from whole blood using nanopore sequencing
Head et al. RNA purification and expression analysis using microarrays and RNA deep sequencing