JP2019534288A5 - - Google Patents
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- Publication number
- JP2019534288A5 JP2019534288A5 JP2019522825A JP2019522825A JP2019534288A5 JP 2019534288 A5 JP2019534288 A5 JP 2019534288A5 JP 2019522825 A JP2019522825 A JP 2019522825A JP 2019522825 A JP2019522825 A JP 2019522825A JP 2019534288 A5 JP2019534288 A5 JP 2019534288A5
- Authority
- JP
- Japan
- Prior art keywords
- delivery device
- pain
- transdermal delivery
- subject
- dexmedetomidine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 230000037317 transdermal delivery Effects 0.000 claims 14
- 208000002193 Pain Diseases 0.000 claims 8
- 238000001356 surgical procedure Methods 0.000 claims 8
- HRLIOXLXPOHXTA-NSHDSACASA-N dexmedetomidine Chemical compound C1([C@@H](C)C=2C(=C(C)C=CC=2)C)=CN=C[N]1 HRLIOXLXPOHXTA-NSHDSACASA-N 0.000 claims 6
- 229960004253 dexmedetomidine Drugs 0.000 claims 6
- 239000012530 fluid Substances 0.000 claims 3
- 230000036571 hydration Effects 0.000 claims 3
- 238000006703 hydration reaction Methods 0.000 claims 3
- 208000001294 Nociceptive Pain Diseases 0.000 claims 2
- 238000010521 absorption reaction Methods 0.000 claims 2
- 206010058019 Cancer Pain Diseases 0.000 claims 1
- 208000000094 Chronic Pain Diseases 0.000 claims 1
- 208000007914 Labor Pain Diseases 0.000 claims 1
- 208000035945 Labour pain Diseases 0.000 claims 1
- 206010028980 Neoplasm Diseases 0.000 claims 1
- BRUQQQPBMZOVGD-XFKAJCMBSA-N Oxycodone Chemical compound O=C([C@@H]1O2)CC[C@@]3(O)[C@H]4CC5=CC=C(OC)C2=C5[C@@]13CCN4C BRUQQQPBMZOVGD-XFKAJCMBSA-N 0.000 claims 1
- 208000004550 Postoperative Pain Diseases 0.000 claims 1
- 239000004820 Pressure-sensitive adhesive Substances 0.000 claims 1
- 208000005298 acute pain Diseases 0.000 claims 1
- 238000011882 arthroplasty Methods 0.000 claims 1
- 210000000988 bone and bone Anatomy 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
- 210000003127 knee Anatomy 0.000 claims 1
- 238000002357 laparoscopic surgery Methods 0.000 claims 1
- 208000004296 neuralgia Diseases 0.000 claims 1
- 208000021722 neuropathic pain Diseases 0.000 claims 1
- 229960002085 oxycodone Drugs 0.000 claims 1
- 230000036470 plasma concentration Effects 0.000 claims 1
- 210000004872 soft tissue Anatomy 0.000 claims 1
- 238000013334 tissue model Methods 0.000 claims 1
- 208000009935 visceral pain Diseases 0.000 claims 1
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022206760A JP2023036825A (ja) | 2016-10-31 | 2022-12-23 | デクスメデトミジン経皮送達デバイスを用いた疼痛管理の方法 |
| JP2025071090A JP2025108704A (ja) | 2016-10-31 | 2025-04-23 | デクスメデトミジン経皮送達デバイスを用いた疼痛管理の方法 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662415248P | 2016-10-31 | 2016-10-31 | |
| US62/415,248 | 2016-10-31 | ||
| US201762547582P | 2017-08-18 | 2017-08-18 | |
| US62/547,582 | 2017-08-18 | ||
| PCT/US2017/059357 WO2018081812A2 (en) | 2016-10-31 | 2017-10-31 | Methods of managing pain using dexmedetomidine transdermal delivery devices |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022206760A Division JP2023036825A (ja) | 2016-10-31 | 2022-12-23 | デクスメデトミジン経皮送達デバイスを用いた疼痛管理の方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019534288A JP2019534288A (ja) | 2019-11-28 |
| JP2019534288A5 true JP2019534288A5 (enExample) | 2020-04-23 |
Family
ID=62020311
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019522825A Withdrawn JP2019534288A (ja) | 2016-10-31 | 2017-10-31 | デクスメデトミジン経皮送達デバイスを用いた疼痛管理の方法 |
| JP2022206760A Withdrawn JP2023036825A (ja) | 2016-10-31 | 2022-12-23 | デクスメデトミジン経皮送達デバイスを用いた疼痛管理の方法 |
| JP2025071090A Pending JP2025108704A (ja) | 2016-10-31 | 2025-04-23 | デクスメデトミジン経皮送達デバイスを用いた疼痛管理の方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022206760A Withdrawn JP2023036825A (ja) | 2016-10-31 | 2022-12-23 | デクスメデトミジン経皮送達デバイスを用いた疼痛管理の方法 |
| JP2025071090A Pending JP2025108704A (ja) | 2016-10-31 | 2025-04-23 | デクスメデトミジン経皮送達デバイスを用いた疼痛管理の方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20180117012A1 (enExample) |
| EP (1) | EP3532038A4 (enExample) |
| JP (3) | JP2019534288A (enExample) |
| KR (4) | KR20210113439A (enExample) |
| CN (1) | CN110022865A (enExample) |
| BR (1) | BR112019006955A2 (enExample) |
| CA (1) | CA3038354C (enExample) |
| RU (1) | RU2723761C1 (enExample) |
| TW (1) | TWI764951B (enExample) |
| WO (1) | WO2018081812A2 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20210113439A (ko) * | 2016-10-31 | 2021-09-15 | 테이코쿠 팔마 유에스에이, 인코포레이티드 | 덱스메데토미딘 경피 전달 장치를 이용한 통증을 관리하는 방법 |
| CN110087641B (zh) | 2016-12-20 | 2024-03-12 | 罗曼治疗系统股份公司 | 含有阿塞那平和聚硅氧烷或聚异丁烯的透皮治疗系统 |
| KR102506333B1 (ko) | 2016-12-20 | 2023-03-06 | 에르테에스 로만 테라피-시스테메 아게 | 아세나핀을 함유하는 경피흡수 치료 시스템 |
| CA3045043A1 (en) | 2016-12-31 | 2018-07-05 | Bioxcel Therapeutics, Inc. | Use of sublingual dexmedetomidine for the treatment of agitation |
| CN112533593A (zh) * | 2018-06-20 | 2021-03-19 | 罗曼治疗系统股份公司 | 含有阿塞那平的透皮治疗系统 |
| CN115154440A (zh) | 2018-06-27 | 2022-10-11 | 比奥克斯塞尔医疗股份有限公司 | 含右美托咪定的膜制剂及其制造方法 |
| JP7453994B2 (ja) * | 2019-04-17 | 2024-03-21 | エルテーエス ローマン テラピー－ジステーメ アーゲー | 経皮治療システム |
| WO2021016112A2 (en) | 2019-07-19 | 2021-01-28 | Bioxcel Therapeutics, Inc. | Non-sedating dexmedetomidine treatment regimens |
| WO2021026377A1 (en) * | 2019-08-07 | 2021-02-11 | Alkermes, Inc. | Lactam-containing compounds for the treatment of pain |
| WO2021026378A1 (en) * | 2019-08-07 | 2021-02-11 | Alkermes, Inc. | Indole compounds for the treatment of pain |
| WO2021026375A1 (en) * | 2019-08-07 | 2021-02-11 | Alkermes, Inc. | Fused bicyclic compounds for the treatment of pain |
| WO2021026380A1 (en) * | 2019-08-07 | 2021-02-11 | Alkermes, Inc. | Phenyltriazole compounds for the treatment of pain |
| CN111281850A (zh) * | 2020-03-14 | 2020-06-16 | 周琛 | 止痛药物组合物及其用途 |
| CN116098876A (zh) * | 2021-11-11 | 2023-05-12 | 北京泰德制药股份有限公司 | 一种右美托咪定透皮贴剂及其制备方法和应用 |
| WO2024037545A1 (zh) * | 2022-08-17 | 2024-02-22 | 宜昌人福药业有限责任公司 | 右美托咪定经皮组合物、透皮贴剂及其制备方法和应用 |
| US11806334B1 (en) | 2023-01-12 | 2023-11-07 | Bioxcel Therapeutics, Inc. | Non-sedating dexmedetomidine treatment regimens |
| US20250099399A1 (en) * | 2023-09-05 | 2025-03-27 | Teikoku Pharma Usa, Inc. | Transdermal delivery patch for treating pain |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2215206B (en) * | 1988-02-29 | 1991-07-03 | Farmos Oy | 4-substituted imidazole derivatives useful in perioperative care |
| US5124157A (en) * | 1989-08-18 | 1992-06-23 | Cygnus Therapeutic Systems | Method and device for administering dexmedetomidine transdermally |
| JP2819236B2 (ja) * | 1994-05-06 | 1998-10-30 | 日東電工株式会社 | 経皮吸収製剤 |
| AU4341401A (en) * | 2000-03-10 | 2001-09-24 | Durect Corp | Opioid formulations |
| US8629172B2 (en) * | 2008-04-18 | 2014-01-14 | Warsaw Orthopedic, Inc. | Methods and compositions for treating post-operative pain comprising clonidine |
| JP2011524345A (ja) * | 2008-06-04 | 2011-09-01 | コーダ セラピューティクス， インコーポレイテッド | ギャップジャンクション調節化合物を用いる疼痛の治療 |
| RU2012133969A (ru) * | 2010-01-08 | 2014-02-20 | Рекро Фарма, Инк. | Локальные трансдермальные композиции дексмедетомидина и способы их применения |
| US20130096170A1 (en) * | 2011-10-14 | 2013-04-18 | Hospira, Inc. | Methods of treating pediatric patients using dexmedetomidine |
| US11547676B2 (en) * | 2012-12-28 | 2023-01-10 | Teikoku Seiyaku Co., Ltd. | Extended buprenorphine transdermal delivery compositions and methods for using the same |
| WO2015054063A1 (en) * | 2013-10-07 | 2015-04-16 | Teikoku Pharma Usa, Inc. | Methods and compositions for treating withdrawal syndromes using non-sedative dexmedetomidine transdermal compositions |
| CN105764496B (zh) * | 2013-10-07 | 2020-09-25 | 帝国制药美国公司 | 用于经皮递送非镇静量的右旋美托咪啶的方法和组合物 |
| KR20180095733A (ko) * | 2013-10-07 | 2018-08-27 | 테이코쿠 팔마 유에스에이, 인코포레이티드 | 덱스메데토미딘 경피 조성물을 포함하는 통증을 관리하기 위한 방법 및 조성물 |
| TWI704933B (zh) * | 2013-10-07 | 2020-09-21 | 美商帝國製藥美國股份有限公司 | 右美托咪啶經皮輸送裝置及使用其之方法 |
| JP6469587B2 (ja) * | 2013-12-18 | 2019-02-13 | 丸石製薬株式会社 | 含水型貼付剤 |
| KR20210113439A (ko) * | 2016-10-31 | 2021-09-15 | 테이코쿠 팔마 유에스에이, 인코포레이티드 | 덱스메데토미딘 경피 전달 장치를 이용한 통증을 관리하는 방법 |
-
2017
- 2017-10-31 KR KR1020217028734A patent/KR20210113439A/ko not_active Ceased
- 2017-10-31 JP JP2019522825A patent/JP2019534288A/ja not_active Withdrawn
- 2017-10-31 WO PCT/US2017/059357 patent/WO2018081812A2/en not_active Ceased
- 2017-10-31 KR KR1020197014883A patent/KR20190060007A/ko not_active Ceased
- 2017-10-31 BR BR112019006955A patent/BR112019006955A2/pt not_active Application Discontinuation
- 2017-10-31 RU RU2019109873A patent/RU2723761C1/ru active
- 2017-10-31 KR KR1020257021141A patent/KR20250105683A/ko active Pending
- 2017-10-31 EP EP17865069.3A patent/EP3532038A4/en active Pending
- 2017-10-31 CA CA3038354A patent/CA3038354C/en active Active
- 2017-10-31 TW TW106137654A patent/TWI764951B/zh active
- 2017-10-31 CN CN201780072175.5A patent/CN110022865A/zh active Pending
- 2017-10-31 US US15/799,602 patent/US20180117012A1/en active Pending
- 2017-10-31 KR KR1020237010276A patent/KR20230048156A/ko not_active Ceased
-
2022
- 2022-12-23 JP JP2022206760A patent/JP2023036825A/ja not_active Withdrawn
-
2025
- 2025-04-23 JP JP2025071090A patent/JP2025108704A/ja active Pending
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