JP2019533426A5 - - Google Patents

Download PDF

Info

Publication number
JP2019533426A5
JP2019533426A5 JP2019501965A JP2019501965A JP2019533426A5 JP 2019533426 A5 JP2019533426 A5 JP 2019533426A5 JP 2019501965 A JP2019501965 A JP 2019501965A JP 2019501965 A JP2019501965 A JP 2019501965A JP 2019533426 A5 JP2019533426 A5 JP 2019533426A5
Authority
JP
Japan
Prior art keywords
seq
nos
antibody
cdr
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
JP2019501965A
Other languages
English (en)
Japanese (ja)
Other versions
JP2019533426A (ja
Filing date
Publication date
Priority claimed from PCT/CA2016/051303 external-priority patent/WO2017079833A1/en
Application filed filed Critical
Priority claimed from PCT/CA2017/050866 external-priority patent/WO2018014126A1/en
Publication of JP2019533426A publication Critical patent/JP2019533426A/ja
Publication of JP2019533426A5 publication Critical patent/JP2019533426A5/ja
Priority to JP2022130540A priority Critical patent/JP7357834B2/ja
Ceased legal-status Critical Current

Links

JP2019501965A 2016-07-18 2017-07-18 アミロイドベータに対する抗体 Ceased JP2019533426A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2022130540A JP7357834B2 (ja) 2016-07-18 2022-08-18 アミロイドベータに対する抗体

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US201662363566P 2016-07-18 2016-07-18
US62/363,566 2016-07-18
CAPCT/CA2016/051303 2016-11-09
PCT/CA2016/051303 WO2017079833A1 (en) 2015-11-09 2016-11-09 Epitopes in amyloid beta mid-region and conformationally-selective antibodies thereto
US201762443766P 2017-01-08 2017-01-08
US62/443,766 2017-01-08
US201762507633P 2017-05-17 2017-05-17
US201762507587P 2017-05-17 2017-05-17
US62/507,633 2017-05-17
US62/507,587 2017-05-17
PCT/CA2017/050866 WO2018014126A1 (en) 2016-07-18 2017-07-18 Antibodies to amyloid beta

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2022130540A Division JP7357834B2 (ja) 2016-07-18 2022-08-18 アミロイドベータに対する抗体

Publications (2)

Publication Number Publication Date
JP2019533426A JP2019533426A (ja) 2019-11-21
JP2019533426A5 true JP2019533426A5 (enExample) 2020-08-27

Family

ID=60991830

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2019501965A Ceased JP2019533426A (ja) 2016-07-18 2017-07-18 アミロイドベータに対する抗体
JP2022130540A Active JP7357834B2 (ja) 2016-07-18 2022-08-18 アミロイドベータに対する抗体

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2022130540A Active JP7357834B2 (ja) 2016-07-18 2022-08-18 アミロイドベータに対する抗体

Country Status (8)

Country Link
US (2) US12071472B2 (enExample)
EP (1) EP3484919A4 (enExample)
JP (2) JP2019533426A (enExample)
KR (1) KR102550991B1 (enExample)
CN (2) CN109476729A (enExample)
AU (1) AU2017299858B2 (enExample)
CA (1) CA3031135A1 (enExample)
WO (1) WO2018014126A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3004498A1 (en) 2015-11-09 2017-05-18 Neil R. Cashman Amyloid beta epitopes and antibodies thereto
WO2017079833A1 (en) 2015-11-09 2017-05-18 The University Of British Columbia Epitopes in amyloid beta mid-region and conformationally-selective antibodies thereto
WO2017079831A1 (en) 2015-11-09 2017-05-18 The University Of British Columbia N-terminal epitopes in amyloid beta and conformationally-selective antibodies thereto
AU2017299858B2 (en) * 2016-07-18 2024-07-25 Promis Neurosciences, Inc. Antibodies to Amyloid beta
US20180125920A1 (en) 2016-11-09 2018-05-10 The University Of British Columbia Methods for preventing and treating A-beta oligomer-associated and/or -induced diseases and conditions
US12286469B2 (en) 2017-07-18 2025-04-29 The University Of British Columbia Humanized antibodies binding to amyloid-beta (A-beta)
JP7330164B2 (ja) * 2017-07-18 2023-08-21 ザ・ユニバーシティ・オブ・ブリティッシュ・コロンビア アミロイドベータに対する抗体
US12325741B2 (en) * 2018-07-17 2025-06-10 Jiangsu Hengrui Medicine Co., Ltd. Anti-Aβ antibodies and antigen-binding fragments thereof
JP7719713B2 (ja) 2018-10-07 2025-08-06 ザ ユニヴァーシティ オブ ブリティッシュ コロンビア α-シヌクレインの立体配座特異的エピトープ、それに対する抗体、およびそれに関連する方法
GB201912008D0 (en) * 2019-08-21 2019-10-02 Cambridge Entpr Ltd Antibody
KR102397684B1 (ko) * 2019-12-09 2022-05-13 (주)옵토레인 항체의 항원 결합 부위에 결합하는 펩티드 및 이를 이용한 분석 방법
KR102504175B1 (ko) * 2020-06-17 2023-02-28 (주)옵토레인 항체의 항원 결합 부위에 결합하는 펩타이드, 이를 이용한 약물 복합체, 바이오센서 및 분석 방법

Family Cites Families (112)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1331443C (en) 1987-05-29 1994-08-16 Charlotte A. Kensil Saponin adjuvant
GB8911525D0 (en) 1989-05-19 1989-07-05 Allied Colloids Ltd Polymeric composition
CA2050918A1 (en) 1990-01-12 1991-07-13 Raju Kucherlapati Generation of xenogeneic antibodies
US6150584A (en) 1990-01-12 2000-11-21 Abgenix, Inc. Human antibodies derived from immunized xenomice
US5427908A (en) 1990-05-01 1995-06-27 Affymax Technologies N.V. Recombinant library screening methods
GB9015198D0 (en) 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
US5770429A (en) 1990-08-29 1998-06-23 Genpharm International, Inc. Transgenic non-human animals capable of producing heterologous antibodies
US5283185A (en) 1991-08-28 1994-02-01 University Of Tennessee Research Corporation Method for delivering nucleic acids into cells
US5766846A (en) 1992-07-10 1998-06-16 Athena Neurosciences Methods of screening for compounds which inhibit soluble β-amyloid peptide production
US5562909A (en) 1993-07-12 1996-10-08 Massachusetts Institute Of Technology Phosphazene polyelectrolytes as immunoadjuvants
AU7642494A (en) 1993-08-31 1995-03-22 Gliatech Inc. Inhibition of beta amyloid binding to glycosaminoglycans for treatment of alzheimer's disease
GB9326174D0 (en) 1993-12-22 1994-02-23 Biocine Sclavo Mucosal adjuvant
US20030072774A1 (en) 1994-06-10 2003-04-17 Diane M. Gajewczyk Proteinaceous adjuvants
US6019982A (en) 1994-08-26 2000-02-01 The Administrators Of The Tulane Educational Fund Mutant enterotoxin effective as a non-toxic oral adjuvant
FR2726764B1 (fr) 1994-11-14 1997-01-31 Pasteur Merieux Serums Vacc Adjuvant pour composition vaccinale
WO1996028471A1 (en) 1995-03-14 1996-09-19 Praecis Pharmaceuticals Incorporated Modulators of amyloid aggregation
AU1072897A (en) 1995-12-12 1997-07-03 Karolinska Innovations Ab Peptide binding the klvff-sequence of amyloid beta
US5735814A (en) 1996-04-30 1998-04-07 Medtronic, Inc. Techniques of treating neurodegenerative disorders by brain infusion
US6043283A (en) 1996-09-20 2000-03-28 Baylor College Of Medicine Tyramine compounds and their neuronal effects
US6071493A (en) 1996-09-20 2000-06-06 Baylor College Of Medicine Method of screening for an agent that inhibits mononuclear phagocyte-plaque component complex formation
US7790856B2 (en) 1998-04-07 2010-09-07 Janssen Alzheimer Immunotherapy Humanized antibodies that recognize beta amyloid peptide
US20080050367A1 (en) 1998-04-07 2008-02-28 Guriq Basi Humanized antibodies that recognize beta amyloid peptide
US7179892B2 (en) 2000-12-06 2007-02-20 Neuralab Limited Humanized antibodies that recognize beta amyloid peptide
US6913745B1 (en) 1997-12-02 2005-07-05 Neuralab Limited Passive immunization of Alzheimer's disease
TWI239847B (en) 1997-12-02 2005-09-21 Elan Pharm Inc N-terminal fragment of Abeta peptide and an adjuvant for preventing and treating amyloidogenic disease
US7588766B1 (en) 2000-05-26 2009-09-15 Elan Pharma International Limited Treatment of amyloidogenic disease
US6761888B1 (en) 2000-05-26 2004-07-13 Neuralab Limited Passive immunization treatment of Alzheimer's disease
US7964192B1 (en) 1997-12-02 2011-06-21 Janssen Alzheimer Immunotherapy Prevention and treatment of amyloidgenic disease
US7012061B1 (en) 1998-10-19 2006-03-14 New York University Method for increasing the permeability of the blood brain barrier
UA81216C2 (en) 1999-06-01 2007-12-25 Prevention and treatment of amyloid disease
US20020094335A1 (en) 1999-11-29 2002-07-18 Robert Chalifour Vaccine for the prevention and treatment of alzheimer's and amyloid related diseases
JP2004500354A (ja) 1999-11-29 2004-01-08 ニューロケム インコーポレーティッド 全d体ペプチドを含む、アルツハイマー病およびアミロイド関連疾患の予防および処置のためのワクチン
EP1257584B2 (en) 2000-02-24 2013-03-06 Washington University St. Louis Humanized antibodies that sequester amyloid beta peptide
AU2007234495A1 (en) 2000-09-08 2007-12-06 Board Of Regents, The University Of Texas System Biopanning and rapid analysis of selective interactive ligands (BRASIL)
US7700751B2 (en) 2000-12-06 2010-04-20 Janssen Alzheimer Immunotherapy Humanized antibodies that recognize β-amyloid peptide
TWI255272B (en) 2000-12-06 2006-05-21 Guriq Basi Humanized antibodies that recognize beta amyloid peptide
CA2436789A1 (en) 2000-12-19 2002-08-22 Palatin Technologies, Inc. Identification of target-specific folding sites in peptides and proteins
AR038568A1 (es) 2002-02-20 2005-01-19 Hoffmann La Roche Anticuerpos anti-a beta y su uso
MY139983A (en) 2002-03-12 2009-11-30 Janssen Alzheimer Immunotherap Humanized antibodies that recognize beta amyloid peptide
EP1911765A3 (en) 2002-07-24 2008-04-23 Innogenetics N.V. Prevention, treatment and diagnosis of diseases associated with Beta-Amyloid formation and/or aggregation
WO2010011999A2 (en) 2008-07-25 2010-01-28 The Regents Of The University Of California Methods and compositions for eliciting an amyloid-selective immune response
WO2004029629A1 (en) 2002-09-27 2004-04-08 Janssen Pharmaceutica N.V. N-11 truncated amyloid-beta nomoclonal antibodies, compositions, methods and uses
MXPA05006940A (es) 2002-12-24 2006-02-22 Neurochem Int Ltd Formulaciones terapeuticas para el tratamiento de enfermedades relacionadas con beta - amiloide.
WO2004071408A2 (en) 2003-02-10 2004-08-26 Applied Molecular Evolution, Inc. Aβ BINDING MOLECULES
CN101245105A (zh) * 2003-03-28 2008-08-20 森托科尔公司 抗淀粉状蛋白抗体、组合物、方法和用途
PE20050627A1 (es) 2003-05-30 2005-08-10 Wyeth Corp Anticuerpos humanizados que reconocen el peptido beta amiloideo
AU2004272112A1 (en) 2003-09-12 2005-03-24 The Regents Of The University Of California Monoclonal antibodies specific for conformational epitopes of prefibrillar aggregates
CN1562050A (zh) 2004-03-24 2005-01-12 中国海洋大学 褐藻酸寡糖在抗痴呆、抗糖尿病中的应用
WO2005095633A1 (en) 2004-04-02 2005-10-13 Queen's University At Kingston A cell culture system for modelling serum amyloid a amyloidogenesis and identifying amyloid modulating compounds
WO2006066049A2 (en) 2004-12-15 2006-06-22 Neuralab Limited Humanized antibodies that recognize beta amyloid peptide
CA2590337C (en) 2004-12-15 2017-07-11 Neuralab Limited Humanized amyloid beta antibodies for use in improving cognition
EP1676859A1 (en) 2004-12-30 2006-07-05 Pevion Biotech Ltd. Immunogenic compositions of cyclic peptides derived from the beta-amyloid peptide
ES2259270B1 (es) 2005-03-09 2007-11-01 Consejo Superior De Investigaciones Cientificas Metodo de diagnostico in vitro de la enfermedad de alzheimer mediante un anticuerpo monoclonal.
AU2006251832A1 (en) 2005-05-27 2006-11-30 Queen's University At Kingston Treatment of protein folding disorders
EP1951750A4 (en) 2005-11-10 2009-12-09 Roskamp Res Llc MODULATION OF THE ANGIOGENESIS BY A-BETA PEPTIDE FRAGMENTS
EP1960428B1 (en) 2005-12-12 2011-07-27 F. Hoffmann-La Roche AG Antibodies against amyloid beta with glycosylation in the variable region
US8784810B2 (en) 2006-04-18 2014-07-22 Janssen Alzheimer Immunotherapy Treatment of amyloidogenic diseases
HUE033466T2 (en) 2006-10-02 2017-12-28 Ac Immune Sa Humanized antibody to beta-amyloid
SI2842967T1 (sl) 2007-01-18 2017-01-31 Eli Lilly And Company Pegilirani amiloid beta fab
US8003097B2 (en) 2007-04-18 2011-08-23 Janssen Alzheimer Immunotherapy Treatment of cerebral amyloid angiopathy
NZ599497A (en) 2007-06-12 2013-11-29 Ac Immune Sa Humanized antibodies to amyloid beta
CL2008001742A1 (es) 2007-06-12 2008-11-21 Ac Immune Sa Anticuerpo monoclonal que reconoce un epitope conformacional y se une a peptidos amiloides solubles polimericos y peptidos amiloides oligomericos; polinucleotido que lo codifica; composicion que lo comprende; y su uso para tratar enfermedades asociados a proteinas amiloides.
PT2182983E (pt) 2007-07-27 2014-09-01 Janssen Alzheimer Immunotherap Tratamento de doenças amiloidogénicas com anticorpos anti-abeta humanizados
SG178809A1 (en) 2007-10-05 2012-03-29 Genentech Inc Use of anti-amyloid beta antibody in ocular diseases
WO2009048537A2 (en) 2007-10-05 2009-04-16 Genentech, Inc. Humanized antibody
WO2009048631A1 (en) 2007-10-11 2009-04-16 University Of Tennessee Research Foundation PREPARATION OF PURIFIED COVALENTYLY CROSS-LINKED A β OLIGOMERS AND USES THEREOF
JO3076B1 (ar) 2007-10-17 2017-03-15 Janssen Alzheimer Immunotherap نظم العلاج المناعي المعتمد على حالة apoe
AP2957A (en) 2007-10-29 2014-08-31 Inst Nat Sante Rech Med New antibodies specific of the Beta-amyloid peptides and their uses as diagnostic agents or drugs
MY158903A (en) 2007-11-16 2016-11-30 Univ Rockefeller Antibodies specific for the protofibril form of beta-amyloid protein
EP2237803B1 (en) 2007-12-28 2015-07-01 Prothena Biosciences Limited Treatment and prophylaxis of amyloidosis
WO2009143489A2 (en) 2008-05-22 2009-11-26 Archer Pharmaceuticals, Inc. Modulation of angiogenesis by a-beta peptide fragments
AT506820B1 (de) 2008-06-12 2011-07-15 Affiris Forschungs Und Entwicklungs Gmbh Vakzine gegen alzheimer-krankheit
AT506819B1 (de) * 2008-06-12 2011-06-15 Affiris Forschungs Und Entwicklungs Gmbh Vakzin zur behandlung von alzheimer-krankheit
US20110092436A1 (en) 2008-06-12 2011-04-21 Affiris Ag Compounds for treating symptoms associated with parkinson's disease
KR101694788B1 (ko) 2008-07-01 2017-01-13 드 슈타트 데르 네덜란덴, 베르테겐부어디그트 두어 드 미니스터 반 베이웨이에스, 미니스테리 반 폭스겐트존하이트, 벨지인 엔 스포츠 아밀로이드 접힘 매개체에 대한 백신
US9801865B2 (en) 2008-09-24 2017-10-31 The United States Of America As Represented By The Department Of Veteran Affairs Materials and methods for diagnosis, prevention and/or treatment of stress disorders and conditions associated with abeta peptide aggregation
JP5898495B2 (ja) 2008-10-06 2016-04-06 ザ ユニヴァーシティ オブ ブリティッシュ コロンビア ミスフォールドタンパク質エピトープを予測するための方法およびシステム
US9067981B1 (en) 2008-10-30 2015-06-30 Janssen Sciences Ireland Uc Hybrid amyloid-beta antibodies
ES2641612T3 (es) * 2009-04-17 2017-11-10 Immunas Pharma, Inc. Anticuerpos que se unen específicamente a oligómeros de beta A y uso de los mismos
WO2010128139A1 (en) 2009-05-08 2010-11-11 Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts, Universitätsmedizin Biomarkers and methods for diagnosing alzheimer's disease and/ or mild cognitive impairment
CN102574915B (zh) * 2009-08-06 2014-10-22 伊缪纳斯制药株式会社 特异性结合Aβ寡聚体的抗体及其用途
EP2463369A4 (en) * 2009-08-07 2013-09-18 Kyowa Hakko Kirin Co Ltd HUMANIZED ANTIBODIES AGAINST AMYLOID B OLIGOMERS
SG179095A1 (en) 2009-09-18 2012-04-27 Probiodrug Ag Novel assay for the detection of amyloid beta peptides
HRP20180230T8 (hr) 2010-02-26 2021-04-30 Bioarctic Neuroscience Ab Protutijela koja se vežu na protofibrile i njihova upotreba u terapijskim i dijagnostičkim postupcima kod parkinsonove bolesti, demencije s lewyjevim tijelima i drugih alfa-sinukleinopatija
US9216217B2 (en) 2010-03-03 2015-12-22 The University Of British Columbia Oligomer-specific amyloid beta epitope and antibodies
AU2011239966B2 (en) 2010-04-16 2014-05-08 Ac Immune S.A. Novel compounds for the treatment of diseases associated with amyloid or amyloid-like proteins
US20110256064A1 (en) 2010-04-16 2011-10-20 Ac Immune, S.A. Novel Compounds for the Treatment of Diseases Associated with Amyloid or Amyloid-like Proteins
MX358739B (es) 2010-08-14 2018-09-03 Abbvie Inc Star Proteinas de union a amiloide beta.
AU2011315920B2 (en) 2010-10-15 2016-04-28 The Board Of Regents Of The University Of Texas System Antibodies that bind amyloid oligomers
FR2966827B1 (fr) 2010-10-27 2014-08-22 Kimonella Ventures Ltd Compose peptidique utile pour l'inhibition de la formation de plaques amyloides
US20120328605A1 (en) 2010-10-27 2012-12-27 Daniel Larocque Compositions and uses
WO2012104824A1 (en) 2011-02-04 2012-08-09 Ecole polytechnique fédérale de Lausanne (EPFL) Therapeutic antibodies targeting app-c99
EP2511296A1 (en) 2011-04-12 2012-10-17 Araclón Biotech, S. L. Antibody, kit and method for determination of amyloid peptides
GB201113570D0 (en) 2011-08-05 2011-09-21 Glaxosmithkline Biolog Sa Vaccine
CN104093454A (zh) 2011-11-10 2014-10-08 坎格尼美国股份有限公司 治疗阿耳茨海默氏病的组合物和方法
EP2659908A1 (en) 2012-05-01 2013-11-06 Affiris AG Compositions
AU2013305848B2 (en) 2012-08-21 2020-10-15 Institute For Molecular Medicine, Inc. Compositions and methods related to diseases associated with deposits of amyloid, Tau, and alpha-synuclein
EP2787347A1 (en) 2013-04-03 2014-10-08 Affiris AG Method for detecting Aß-specific antibodies in a biological sample
AU2014305658A1 (en) 2013-08-05 2016-02-11 St. Vincent's Institute Of Medical Research An antibody therapy for amyloid beta disease
KR20160044042A (ko) * 2013-08-28 2016-04-22 스템센트알엑스 인코포레이티드 부위-특이적 항체 접합 방법 및 조성물
CA2938129A1 (en) 2014-02-03 2015-08-06 Cangene Corporation Humanized beta-amyloid binding molecules and uses thereof
WO2016138525A1 (en) * 2015-02-27 2016-09-01 University Of Washington Polypeptide assemblies and methods for the production thereof
US20170021020A1 (en) 2015-07-23 2017-01-26 The Board Of Trustees Of The Leland Stanford Junior University Monoclonal antibody and vaccine targeting filamentous bacteriophage
SI3334431T1 (sl) 2015-08-11 2020-01-31 Novartis Ag 5-bromo-2,6-di-(1h-pirazol-l-il)pyrimidin-4-amin za uporabo v zdravljenju raka
CA3004498A1 (en) 2015-11-09 2017-05-18 Neil R. Cashman Amyloid beta epitopes and antibodies thereto
CN108475298A (zh) * 2015-11-09 2018-08-31 英属哥伦比亚大学 通过集体坐标偏置预测错误折叠的蛋白质表位的系统和方法
WO2017079831A1 (en) 2015-11-09 2017-05-18 The University Of British Columbia N-terminal epitopes in amyloid beta and conformationally-selective antibodies thereto
CA3004496A1 (en) 2015-11-09 2017-05-18 Neil R. Cashman Epitopes in amyloid beta and conformationally-selective antibodies thereto
CN108368160A (zh) 2015-11-09 2018-08-03 英属哥伦比亚大学 淀粉样蛋白β中的C-末端表位及其构象选择性抗体
WO2017079833A1 (en) 2015-11-09 2017-05-18 The University Of British Columbia Epitopes in amyloid beta mid-region and conformationally-selective antibodies thereto
AU2017299858B2 (en) 2016-07-18 2024-07-25 Promis Neurosciences, Inc. Antibodies to Amyloid beta
US20180125920A1 (en) * 2016-11-09 2018-05-10 The University Of British Columbia Methods for preventing and treating A-beta oligomer-associated and/or -induced diseases and conditions

Similar Documents

Publication Publication Date Title
JP2019533426A5 (enExample)
AU2017367734B2 (en) Radiolabeled anti-PD-l1 antibodies for immuno-PET imaging
JP7357834B2 (ja) アミロイドベータに対する抗体
JP6952827B2 (ja) 血液脳関門輸送分子およびそれらの使用
RU2557319C2 (ru) ГУМАНИЗИРОВАННЫЕ АНТИТЕЛА ПРОТИВ CD79b И ИММУНОКОНЪЮГАТЫ И СПОСОБЫ ПРИМЕНЕНИЯ
CN102471380B (zh) 抗FcRH5抗体和免疫偶联物及使用方法
TWI392503B (zh) 抗-cd79b抗體及免疫共軛物及使用方法
JP2018500014A5 (enExample)
JP2020513791A5 (enExample)
IL261666B2 (en) Binding proteins and methods of use thereof
JP2017514143A5 (enExample)
JP2020502996A5 (enExample)
JP2013500941A5 (enExample)
JP2016511254A5 (enExample)
JP2020502271A5 (enExample)
JP2013506428A5 (enExample)
JP2017505604A5 (enExample)
JP2011509245A5 (enExample)
JP2014511179A5 (enExample)
JP7452829B2 (ja) アミロイドベータのエピトープおよびそれに対する抗体
JP2019505166A5 (enExample)
CN108368160A (zh) 淀粉样蛋白β中的C-末端表位及其构象选择性抗体
CA3084098A1 (en) Binding molecules that specifically bind to tau
JP2019507580A5 (enExample)
KR20190133191A (ko) 타우에 특이적으로 결합하는 결합 분자