|
CA1331443C
(en)
|
1987-05-29 |
1994-08-16 |
Charlotte A. Kensil |
Saponin adjuvant
|
|
GB8911525D0
(en)
|
1989-05-19 |
1989-07-05 |
Allied Colloids Ltd |
Polymeric composition
|
|
US6150584A
(en)
|
1990-01-12 |
2000-11-21 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
DE69133566T2
(de)
|
1990-01-12 |
2007-12-06 |
Amgen Fremont Inc. |
Bildung von xenogenen Antikörpern
|
|
US5427908A
(en)
|
1990-05-01 |
1995-06-27 |
Affymax Technologies N.V. |
Recombinant library screening methods
|
|
GB9015198D0
(en)
|
1990-07-10 |
1990-08-29 |
Brien Caroline J O |
Binding substance
|
|
US5770429A
(en)
|
1990-08-29 |
1998-06-23 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5283185A
(en)
|
1991-08-28 |
1994-02-01 |
University Of Tennessee Research Corporation |
Method for delivering nucleic acids into cells
|
|
US5766846A
(en)
|
1992-07-10 |
1998-06-16 |
Athena Neurosciences |
Methods of screening for compounds which inhibit soluble β-amyloid peptide production
|
|
US5562909A
(en)
|
1993-07-12 |
1996-10-08 |
Massachusetts Institute Of Technology |
Phosphazene polyelectrolytes as immunoadjuvants
|
|
AU7642494A
(en)
|
1993-08-31 |
1995-03-22 |
Gliatech Inc. |
Inhibition of beta amyloid binding to glycosaminoglycans for treatment of alzheimer's disease
|
|
GB9326174D0
(en)
|
1993-12-22 |
1994-02-23 |
Biocine Sclavo |
Mucosal adjuvant
|
|
US20030072774A1
(en)
|
1994-06-10 |
2003-04-17 |
Diane M. Gajewczyk |
Proteinaceous adjuvants
|
|
US6019982A
(en)
|
1994-08-26 |
2000-02-01 |
The Administrators Of The Tulane Educational Fund |
Mutant enterotoxin effective as a non-toxic oral adjuvant
|
|
FR2726764B1
(fr)
|
1994-11-14 |
1997-01-31 |
Pasteur Merieux Serums Vacc |
Adjuvant pour composition vaccinale
|
|
CA2214247C
(en)
|
1995-03-14 |
2004-02-10 |
Praecis Pharmaceuticals Incorporated |
Modulators of amyloid aggregation
|
|
EP0866805A1
(en)
|
1995-12-12 |
1998-09-30 |
Karolinska Innovations AB |
PEPTIDE BINDING THE KLVFF-SEQUENCE OF AMYLOID $g(b)
|
|
US5735814A
(en)
|
1996-04-30 |
1998-04-07 |
Medtronic, Inc. |
Techniques of treating neurodegenerative disorders by brain infusion
|
|
US6071493A
(en)
|
1996-09-20 |
2000-06-06 |
Baylor College Of Medicine |
Method of screening for an agent that inhibits mononuclear phagocyte-plaque component complex formation
|
|
US6043283A
(en)
|
1996-09-20 |
2000-03-28 |
Baylor College Of Medicine |
Tyramine compounds and their neuronal effects
|
|
TWI239847B
(en)
|
1997-12-02 |
2005-09-21 |
Elan Pharm Inc |
N-terminal fragment of Abeta peptide and an adjuvant for preventing and treating amyloidogenic disease
|
|
US7964192B1
(en)
|
1997-12-02 |
2011-06-21 |
Janssen Alzheimer Immunotherapy |
Prevention and treatment of amyloidgenic disease
|
|
US7588766B1
(en)
|
2000-05-26 |
2009-09-15 |
Elan Pharma International Limited |
Treatment of amyloidogenic disease
|
|
US20080050367A1
(en)
|
1998-04-07 |
2008-02-28 |
Guriq Basi |
Humanized antibodies that recognize beta amyloid peptide
|
|
US7179892B2
(en)
|
2000-12-06 |
2007-02-20 |
Neuralab Limited |
Humanized antibodies that recognize beta amyloid peptide
|
|
US6761888B1
(en)
|
2000-05-26 |
2004-07-13 |
Neuralab Limited |
Passive immunization treatment of Alzheimer's disease
|
|
US6913745B1
(en)
|
1997-12-02 |
2005-07-05 |
Neuralab Limited |
Passive immunization of Alzheimer's disease
|
|
US7790856B2
(en)
|
1998-04-07 |
2010-09-07 |
Janssen Alzheimer Immunotherapy |
Humanized antibodies that recognize beta amyloid peptide
|
|
US7012061B1
(en)
|
1998-10-19 |
2006-03-14 |
New York University |
Method for increasing the permeability of the blood brain barrier
|
|
UA81216C2
(en)
|
1999-06-01 |
2007-12-25 |
|
Prevention and treatment of amyloid disease
|
|
AU784312B2
(en)
|
1999-11-29 |
2006-03-09 |
Bellus Health (International) Limited |
Vaccine for the prevention and treatment of alzheimer's and amyloid related diseases
|
|
US20020094335A1
(en)
|
1999-11-29 |
2002-07-18 |
Robert Chalifour |
Vaccine for the prevention and treatment of alzheimer's and amyloid related diseases
|
|
KR100767146B1
(ko)
|
2000-02-24 |
2007-10-15 |
워싱톤 유니버시티 |
Ａβ 펩티드를 격리시키는 인간화 항체
|
|
AU2007234495A1
(en)
|
2000-09-08 |
2007-12-06 |
Board Of Regents, The University Of Texas System |
Biopanning and rapid analysis of selective interactive ligands (BRASIL)
|
|
US7700751B2
(en)
|
2000-12-06 |
2010-04-20 |
Janssen Alzheimer Immunotherapy |
Humanized antibodies that recognize β-amyloid peptide
|
|
PE20020574A1
(es)
|
2000-12-06 |
2002-07-02 |
Wyeth Corp |
Anticuerpos humanizados que reconocen el peptido amiloideo beta
|
|
CA2436789A1
(en)
|
2000-12-19 |
2002-08-22 |
Palatin Technologies, Inc. |
Identification of target-specific folding sites in peptides and proteins
|
|
AR038568A1
(es)
|
2002-02-20 |
2005-01-19 |
Hoffmann La Roche |
Anticuerpos anti-a beta y su uso
|
|
MY139983A
(en)
|
2002-03-12 |
2009-11-30 |
Janssen Alzheimer Immunotherap |
Humanized antibodies that recognize beta amyloid peptide
|
|
CA2487528A1
(en)
|
2002-07-24 |
2004-02-12 |
Innogenetics N.V. |
Prevention, treatment and diagnosis of diseases associated with beta-amyloid formation and/or aggregation
|
|
US9535076B2
(en)
|
2002-09-12 |
2017-01-03 |
The Regents Of The University Of California |
Methods and compositions for eliciting an amyloid-selective immune response
|
|
WO2004029629A1
(en)
|
2002-09-27 |
2004-04-08 |
Janssen Pharmaceutica N.V. |
N-11 truncated amyloid-beta nomoclonal antibodies, compositions, methods and uses
|
|
JP2006512417A
(ja)
|
2002-12-24 |
2006-04-13 |
ニューロケム （インターナショナル） リミテッド |
β−アミロイド関連疾患の治療のための治療用製剤
|
|
DE602004027348D1
(de)
|
2003-02-10 |
2010-07-08 |
Applied Molecular Evolution |
Abeta-bindende moleküle
|
|
CN101367874A
(zh)
*
|
2003-03-28 |
2009-02-18 |
森托科尔公司 |
抗淀粉状蛋白抗体、组合物、方法和用途
|
|
PE20050627A1
(es)
|
2003-05-30 |
2005-08-10 |
Wyeth Corp |
Anticuerpos humanizados que reconocen el peptido beta amiloideo
|
|
JP2007527865A
(ja)
|
2003-09-12 |
2007-10-04 |
ザ・レジェンツ・オブ・ザ・ユニバーシティ・オブ・カリフォルニア |
種々の配列を有するタンパク質から形成されたアミロイドに共通の高分子量凝集中間体に特異的なモノクローナル抗体
|
|
CN1562050A
(zh)
|
2004-03-24 |
2005-01-12 |
中国海洋大学 |
褐藻酸寡糖在抗痴呆、抗糖尿病中的应用
|
|
CA2560618A1
(en)
|
2004-04-02 |
2005-10-13 |
Queen's University At Kingston |
A cell culture system for modelling serum amyloid a amyloidogenesis and identifying amyloid modulating compounds
|
|
EP1838854B1
(en)
|
2004-12-15 |
2012-10-31 |
Janssen Alzheimer Immunotherapy |
Antibodies that recognize Beta Amyloid Peptide
|
|
AR052051A1
(es)
|
2004-12-15 |
2007-02-28 |
Neuralab Ltd |
Anticuerpos ab humanizados usados en mejorar la cognicion
|
|
EP1676859A1
(en)
|
2004-12-30 |
2006-07-05 |
Pevion Biotech Ltd. |
Immunogenic compositions of cyclic peptides derived from the beta-amyloid peptide
|
|
ES2259270B1
(es)
|
2005-03-09 |
2007-11-01 |
Consejo Superior De Investigaciones Cientificas |
Metodo de diagnostico in vitro de la enfermedad de alzheimer mediante un anticuerpo monoclonal.
|
|
CA2609980C
(en)
|
2005-05-27 |
2015-10-13 |
Queen's University At Kingston |
Treatment of protein folding disorders
|
|
JP2009516654A
(ja)
|
2005-11-10 |
2009-04-23 |
ロスキャンプ リサーチ， エルエルシー |
Ａ−ベータペプチドによる血管新生の調節
|
|
BRPI0619605B8
(pt)
|
2005-12-12 |
2021-05-25 |
Hoffmann La Roche |
composições compreendendo moléculas de anticorpos contra amilóide beta4 com glicosilação na região variável, usos das mesmas, método de preparação de uma molécula de anticorpo, e kit
|
|
US8784810B2
(en)
|
2006-04-18 |
2014-07-22 |
Janssen Alzheimer Immunotherapy |
Treatment of amyloidogenic diseases
|
|
CN101611054B
(zh)
|
2006-10-02 |
2013-12-25 |
Ac免疫有限公司 |
针对淀粉状蛋白β的人源化抗体
|
|
ES2535641T3
(es)
|
2007-01-18 |
2015-05-13 |
Eli Lilly & Company |
Amiloide beta Fab pegilado
|
|
US8003097B2
(en)
|
2007-04-18 |
2011-08-23 |
Janssen Alzheimer Immunotherapy |
Treatment of cerebral amyloid angiopathy
|
|
AR066987A1
(es)
|
2007-06-12 |
2009-09-23 |
Ac Immune Sa |
Anticuerpo monoclonal contra proteina beta-amiloide
|
|
SG182192A1
(en)
|
2007-06-12 |
2012-07-30 |
Ac Immune Sa |
Humanized antibodies to amyloid beta
|
|
JP5889529B2
(ja)
|
2007-07-27 |
2016-03-22 |
ヤンセン・サイエンシズ・アイルランド・ユーシー |
アミロイド原性疾患の処置
|
|
AU2008311365B2
(en)
|
2007-10-05 |
2015-03-12 |
Ac Immune S.A. |
Humanized antibody
|
|
RU2542967C2
(ru)
|
2007-10-05 |
2015-02-27 |
Дженентек, Инк. |
Применение антитела против амилоида бета при глазных заболеваниях
|
|
US20090246191A1
(en)
|
2007-10-11 |
2009-10-01 |
University Of Tennessee Research Foundation |
Preparation of Purified Covalently Cross-linked Abeta Oligomers and Uses Thereof
|
|
JO3076B1
(ar)
|
2007-10-17 |
2017-03-15 |
Janssen Alzheimer Immunotherap |
نظم العلاج المناعي المعتمد على حالة apoe
|
|
NZ585000A
(en)
|
2007-10-29 |
2012-08-31 |
Inst Nat Sante Rech Med |
New antibodies specific of the beta-amyloid peptides and their uses as diagnostic agents or drugs
|
|
ME01026B
(me)
*
|
2007-11-16 |
2012-10-20 |
Univ Rockefeller |
Antitijela specifična za protofibrilni oblik beta-amiloid proteina
|
|
AU2008345022B2
(en)
|
2007-12-28 |
2014-11-06 |
Prothena Biosciences Limited |
Treatment and prophylaxis of amyloidosis
|
|
WO2009143489A2
(en)
|
2008-05-22 |
2009-11-26 |
Archer Pharmaceuticals, Inc. |
Modulation of angiogenesis by a-beta peptide fragments
|
|
AT506819B1
(de)
|
2008-06-12 |
2011-06-15 |
Affiris Forschungs Und Entwicklungs Gmbh |
Vakzin zur behandlung von alzheimer-krankheit
|
|
WO2009149487A2
(en)
|
2008-06-12 |
2009-12-17 |
Affiris Ag |
Compounds for treating symptoms associated with parkinson's disease
|
|
AT506820B1
(de)
|
2008-06-12 |
2011-07-15 |
Affiris Forschungs Und Entwicklungs Gmbh |
Vakzine gegen alzheimer-krankheit
|
|
ES2397641T3
(es)
|
2008-07-01 |
2013-03-08 |
De Staat Der Nederlanden, Vert. Door De Minister Van Vws |
Vacuna contra el intermediario de plegado amiloide
|
|
US9801865B2
(en)
|
2008-09-24 |
2017-10-31 |
The United States Of America As Represented By The Department Of Veteran Affairs |
Materials and methods for diagnosis, prevention and/or treatment of stress disorders and conditions associated with abeta peptide aggregation
|
|
CA2743361C
(en)
|
2008-10-06 |
2021-05-25 |
Neil R. Cashman |
Methods and systems for predicting misfolded protein epitopes
|
|
US9067981B1
(en)
|
2008-10-30 |
2015-06-30 |
Janssen Sciences Ireland Uc |
Hybrid amyloid-beta antibodies
|
|
JP5812418B2
(ja)
|
2009-04-17 |
2015-11-11 |
イムナス・ファーマ株式会社 |
Ａβオリゴマーに特異的に結合する抗体およびその利用
|
|
WO2010128139A1
(en)
|
2009-05-08 |
2010-11-11 |
Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts, Universitätsmedizin |
Biomarkers and methods for diagnosing alzheimer's disease and/ or mild cognitive impairment
|
|
JP5769316B2
(ja)
|
2009-08-06 |
2015-08-26 |
イムナス・ファーマ株式会社 |
Ａβオリゴマーに特異的に結合する抗体およびその利用
|
|
JP5692073B2
(ja)
*
|
2009-08-07 |
2015-04-01 |
協和発酵キリン株式会社 |
抗アミロイドβオリゴマーヒト化抗体
|
|
WO2011033046A1
(en)
|
2009-09-18 |
2011-03-24 |
Probiodrug Ag |
Novel assay for the detection of amyloid beta peptides
|
|
JP5894939B2
(ja)
|
2010-02-26 |
2016-03-30 |
バイオアークティック ニューロサイエンス アーベー |
プロトフィブリル結合抗体ならびにパーキンソン病、レビー小体型認知症および他のα−シヌクレイノパチーの治療および診断方法におけるこれらの使用
|
|
RU2644335C2
(ru)
|
2010-03-03 |
2018-02-08 |
Зе Юниверсити Оф Бритиш Коламбия |
Эпитоп, специфичный к олигомеру амилоида бета, и антитела
|
|
US20110256064A1
(en)
|
2010-04-16 |
2011-10-20 |
Ac Immune, S.A. |
Novel Compounds for the Treatment of Diseases Associated with Amyloid or Amyloid-like Proteins
|
|
RU2603008C2
(ru)
|
2010-04-16 |
2016-11-20 |
Ац Иммуне С.А. |
Новые соединения для лечения заболеваний, связанных с амилоидными или амилоидоподобными белками
|
|
US9062101B2
(en)
|
2010-08-14 |
2015-06-23 |
AbbVie Deutschland GmbH & Co. KG |
Amyloid-beta binding proteins
|
|
CA2817973C
(en)
|
2010-10-15 |
2019-06-25 |
The Board Of Regents Of The University Of Texas System |
Antibodies that bind amyloid oligomers
|
|
US20120321694A1
(en)
|
2010-10-27 |
2012-12-20 |
Daniel Larocque |
Compositions and uses
|
|
FR2966827B1
(fr)
|
2010-10-27 |
2014-08-22 |
Kimonella Ventures Ltd |
Compose peptidique utile pour l'inhibition de la formation de plaques amyloides
|
|
WO2012104824A1
(en)
|
2011-02-04 |
2012-08-09 |
Ecole polytechnique fédérale de Lausanne (EPFL) |
Therapeutic antibodies targeting app-c99
|
|
EP2511296A1
(en)
|
2011-04-12 |
2012-10-17 |
Araclón Biotech, S. L. |
Antibody, kit and method for determination of amyloid peptides
|
|
GB201113570D0
(en)
|
2011-08-05 |
2011-09-21 |
Glaxosmithkline Biolog Sa |
Vaccine
|
|
CA2855669A1
(en)
|
2011-11-10 |
2013-05-16 |
Cangene U.S., Incorporated |
Compositions and methods for treating alzheimer's disease
|
|
EP2659908A1
(en)
|
2012-05-01 |
2013-11-06 |
Affiris AG |
Compositions
|
|
AU2013305848B2
(en)
|
2012-08-21 |
2020-10-15 |
Institute For Molecular Medicine, Inc. |
Compositions and methods related to diseases associated with deposits of amyloid, Tau, and alpha-synuclein
|
|
EP2787347A1
(en)
|
2013-04-03 |
2014-10-08 |
Affiris AG |
Method for detecting Aß-specific antibodies in a biological sample
|
|
AU2014305658A1
(en)
|
2013-08-05 |
2016-02-11 |
St. Vincent's Institute Of Medical Research |
An antibody therapy for amyloid beta disease
|
|
PE20160674A1
(es)
|
2013-08-28 |
2016-07-21 |
Stemcentrx Inc |
Metodos de conjugacion de anticuerpos especificos de sitio y composiciones
|
|
WO2015113169A1
(en)
|
2014-02-03 |
2015-08-06 |
Cnj Holdings, Inc. |
Humanized beta-amyloid binding molecules and uses thereof
|
|
US10501733B2
(en)
*
|
2015-02-27 |
2019-12-10 |
University Of Washington |
Polypeptide assemblies and methods for the production thereof
|
|
US20170021020A1
(en)
|
2015-07-23 |
2017-01-26 |
The Board Of Trustees Of The Leland Stanford Junior University |
Monoclonal antibody and vaccine targeting filamentous bacteriophage
|
|
SG10202111808WA
(en)
|
2015-08-11 |
2021-11-29 |
Novartis Ag |
5-bromo-2,6-di-(1h-pyrazol-1-yl)pyrimidin-4-amine for use in the treatment of cancer
|
|
AU2016354688B2
(en)
*
|
2015-11-09 |
2021-12-16 |
The University Of British Columbia |
Epitopes in Amyloid beta mid-region and conformationally-selective antibodies thereto
|
|
CN108350051A
(zh)
|
2015-11-09 |
2018-07-31 |
英属哥伦比亚大学 |
淀粉样蛋白β中的N-末端表位及其构象选择性抗体
|
|
CA3004593A1
(en)
|
2015-11-09 |
2017-05-18 |
The University Of British Columbia |
Systems and methods for predicting misfolded protein epitopes by collective coordinate biasing
|
|
US20180326027A1
(en)
|
2015-11-09 |
2018-11-15 |
The University Of British Columbia |
Epitopes in amyloid beta and conformationally-selective antibodies thereto
|
|
CA3004498A1
(en)
*
|
2015-11-09 |
2017-05-18 |
Neil R. Cashman |
Amyloid beta epitopes and antibodies thereto
|
|
JP2019505165A
(ja)
|
2015-11-09 |
2019-02-28 |
ザ・ユニバーシティ・オブ・ブリティッシュ・コロンビア |
アミロイドベータのｃ末端エピトープおよびそれに対する立体配座選択的抗体
|
|
EP3484919A4
(en)
|
2016-07-18 |
2020-03-04 |
The University of British Columbia |
ANTI-BETA-AMYLOID ANTIBODIES
|
|
US20180125920A1
(en)
*
|
2016-11-09 |
2018-05-10 |
The University Of British Columbia |
Methods for preventing and treating A-beta oligomer-associated and/or -induced diseases and conditions
|