JP2019532051A5 - - Google Patents

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JP2019532051A5
JP2019532051A5 JP2019515203A JP2019515203A JP2019532051A5 JP 2019532051 A5 JP2019532051 A5 JP 2019532051A5 JP 2019515203 A JP2019515203 A JP 2019515203A JP 2019515203 A JP2019515203 A JP 2019515203A JP 2019532051 A5 JP2019532051 A5 JP 2019532051A5
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pharmaceutically acceptable
acceptable salt
inhibitor
compound
cancer
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JP2019515203A
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JP2019532051A (ja
JP7114575B2 (ja
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Priority claimed from PCT/IB2017/055641 external-priority patent/WO2018051306A1/en
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JP2019515203A 2016-09-19 2017-09-18 Ｒａｆ阻害剤及びｅｒｋ阻害剤を含む治療用組合せ Active JP7114575B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662396504P 2016-09-19 2016-09-19
US62/396,504 2016-09-19
PCT/IB2017/055641 WO2018051306A1 (en) 2016-09-19 2017-09-18 Therapeutic combinations comprising a raf inhibitor and a erk inhibitor

Publications (3)

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JP2019532051A JP2019532051A (ja) 2019-11-07
JP2019532051A5 true JP2019532051A5 (OSRAM) 2020-10-22
JP7114575B2 JP7114575B2 (ja) 2022-08-08

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JP2019515203A Active JP7114575B2 (ja) 2016-09-19 2017-09-18 Ｒａｆ阻害剤及びｅｒｋ阻害剤を含む治療用組合せ

Country Status (11)

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US (2) US10973829B2 (OSRAM)
EP (1) EP3515446B1 (OSRAM)
JP (1) JP7114575B2 (OSRAM)
KR (1) KR102341660B1 (OSRAM)
CN (1) CN109715163B (OSRAM)
AU (1) AU2017329090B9 (OSRAM)
CL (1) CL2019000681A1 (OSRAM)
ES (1) ES2974991T3 (OSRAM)
IL (1) IL264931B (OSRAM)
MX (1) MX386413B (OSRAM)
WO (1) WO2018051306A1 (OSRAM)

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AU2019407159A1 (en) 2018-12-20 2021-07-15 Novartis Ag Combination therapy with a Raf inhibitor and a CKD4/6 inhibitor for use in the treatment of cancer
BR112021022335A2 (pt) 2019-05-13 2021-12-28 Novartis Ag Formas cristalinas de n-(3-(2-(2-hidroxietoxi)-6-morfolinopiridin-4-il)-4-metilfenil)-2 (trifluorome-til)isonicotinamida como inibidores raf para o tratamento de câncer
EP4106756A1 (en) 2020-02-18 2022-12-28 Novartis AG Therapeutic combinations comprising a raf inhibitor for use in treating braf mutant nsclc
US20240000789A1 (en) 2020-05-12 2024-01-04 Novartis Ag Therapeutic combinations comprising a craf inhibitor

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