|
US5288609A
(en)
|
1984-04-27 |
1994-02-22 |
Enzo Diagnostics, Inc. |
Capture sandwich hybridization method and composition
|
|
US4965188A
(en)
|
1986-08-22 |
1990-10-23 |
Cetus Corporation |
Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme
|
|
US4683195A
(en)
|
1986-01-30 |
1987-07-28 |
Cetus Corporation |
Process for amplifying, detecting, and/or-cloning nucleic acid sequences
|
|
US4683202A
(en)
|
1985-03-28 |
1987-07-28 |
Cetus Corporation |
Process for amplifying nucleic acid sequences
|
|
US5011769A
(en)
|
1985-12-05 |
1991-04-30 |
Meiogenics U.S. Limited Partnership |
Methods for detecting nucleic acid sequences
|
|
US5124246A
(en)
|
1987-10-15 |
1992-06-23 |
Chiron Corporation |
Nucleic acid multimers and amplified nucleic acid hybridization assays using same
|
|
US5359100A
(en)
|
1987-10-15 |
1994-10-25 |
Chiron Corporation |
Bifunctional blocked phosphoramidites useful in making nucleic acid mutimers
|
|
US5403711A
(en)
|
1987-11-30 |
1995-04-04 |
University Of Iowa Research Foundation |
Nucleic acid hybridization and amplification method for detection of specific sequences in which a complementary labeled nucleic acid probe is cleaved
|
|
CA1340807C
(en)
|
1988-02-24 |
1999-11-02 |
Lawrence T. Malek |
Nucleic acid amplification process
|
|
US5639611A
(en)
|
1988-12-12 |
1997-06-17 |
City Of Hope |
Allele specific polymerase chain reaction
|
|
CA2036946C
(en)
|
1990-04-06 |
2001-10-16 |
Kenneth V. Deugau |
Indexing linkers
|
|
US5494810A
(en)
|
1990-05-03 |
1996-02-27 |
Cornell Research Foundation, Inc. |
Thermostable ligase-mediated DNA amplifications system for the detection of genetic disease
|
|
US5849481A
(en)
|
1990-07-27 |
1998-12-15 |
Chiron Corporation |
Nucleic acid hybridization assays employing large comb-type branched polynucleotides
|
|
US6872816B1
(en)
|
1996-01-24 |
2005-03-29 |
Third Wave Technologies, Inc. |
Nucleic acid detection kits
|
|
US5994069A
(en)
|
1996-01-24 |
1999-11-30 |
Third Wave Technologies, Inc. |
Detection of nucleic acids by multiple sequential invasive cleavages
|
|
US5846717A
(en)
|
1996-01-24 |
1998-12-08 |
Third Wave Technologies, Inc. |
Detection of nucleic acid sequences by invader-directed cleavage
|
|
US5338671A
(en)
|
1992-10-07 |
1994-08-16 |
Eastman Kodak Company |
DNA amplification with thermostable DNA polymerase and polymerase inhibiting antibody
|
|
SE501439C2
(sv)
|
1993-06-22 |
1995-02-13 |
Pharmacia Lkb Biotech |
Sätt och anordning för analys av polynukleotidsekvenser
|
|
WO1995014106A2
(en)
|
1993-11-17 |
1995-05-26 |
Id Biomedical Corporation |
Cycling probe cleavage detection of nucleic acid sequences
|
|
KR100392057B1
(ko)
|
1993-11-30 |
2003-10-30 |
맥길 유니버시티 |
세포의 CpG 디뉴클레오티드 내의 시토신의 메틸화를 감소하는 방법
|
|
EP0760002B1
(en)
|
1994-04-25 |
2003-08-27 |
Avitech Diagnostics, Inc. |
Detection of mutation by resolvase cleavage
|
|
US5851770A
(en)
|
1994-04-25 |
1998-12-22 |
Variagenics, Inc. |
Detection of mismatches by resolvase cleavage using a magnetic bead support
|
|
WO1996020287A2
(en)
|
1994-12-23 |
1996-07-04 |
Behringwerke Aktiengesellschaft |
Detection of nucleic acids by target-catalyzed product formation
|
|
US5882867A
(en)
|
1995-06-07 |
1999-03-16 |
Dade Behring Marburg Gmbh |
Detection of nucleic acids by formation of template-dependent product
|
|
US5773258A
(en)
|
1995-08-25 |
1998-06-30 |
Roche Molecular Systems, Inc. |
Nucleic acid amplification using a reversibly inactivated thermostable enzyme
|
|
US5854033A
(en)
|
1995-11-21 |
1998-12-29 |
Yale University |
Rolling circle replication reporter systems
|
|
US5965408A
(en)
|
1996-07-09 |
1999-10-12 |
Diversa Corporation |
Method of DNA reassembly by interrupting synthesis
|
|
WO1997023647A1
(en)
|
1995-12-22 |
1997-07-03 |
Behringwerke Aktiengesellschaft |
Homogeneous amplification and detection of nucleic acids
|
|
US5985557A
(en)
|
1996-01-24 |
1999-11-16 |
Third Wave Technologies, Inc. |
Invasive cleavage of nucleic acids
|
|
AU713667B2
(en)
|
1996-04-12 |
1999-12-09 |
Phri Properties, Inc. |
Detection probes, kits and assays
|
|
US6017704A
(en)
|
1996-06-03 |
2000-01-25 |
The Johns Hopkins University School Of Medicine |
Method of detection of methylated nucleic acid using agents which modify unmethylated cytosine and distinguishing modified methylated and non-methylated nucleic acids
|
|
US5786146A
(en)
|
1996-06-03 |
1998-07-28 |
The Johns Hopkins University School Of Medicine |
Method of detection of methylated nucleic acid using agents which modify unmethylated cytosine and distinguishing modified methylated and non-methylated nucleic acids
|
|
US6096273A
(en)
|
1996-11-05 |
2000-08-01 |
Clinical Micro Sensors |
Electrodes linked via conductive oligomers to nucleic acids
|
|
US6251594B1
(en)
|
1997-06-09 |
2001-06-26 |
Usc/Norris Comprehensive Cancer Ctr. |
Cancer diagnostic method based upon DNA methylation differences
|
|
US6013459A
(en)
|
1997-06-12 |
2000-01-11 |
Clinical Micro Sensors, Inc. |
Detection of analytes using reorganization energy
|
|
DE19754482A1
(de)
|
1997-11-27 |
1999-07-01 |
Epigenomics Gmbh |
Verfahren zur Herstellung komplexer DNA-Methylierungs-Fingerabdrücke
|
|
US6063573A
(en)
|
1998-01-27 |
2000-05-16 |
Clinical Micro Sensors, Inc. |
Cycling probe technology using electron transfer detection
|
|
DE69902996T2
(de)
|
1998-02-04 |
2003-04-30 |
Variagenics, Inc. |
Techniken zu detektion von fehlpaarungen
|
|
US6235502B1
(en)
|
1998-09-18 |
2001-05-22 |
Molecular Staging Inc. |
Methods for selectively isolating DNA using rolling circle amplification
|
|
US7700324B1
(en)
|
1998-11-03 |
2010-04-20 |
The Johns Hopkins University School Of Medicine |
Methylated CpG island amplification (MCA)
|
|
WO2002000926A2
(en)
*
|
2000-06-30 |
2002-01-03 |
Epigenomics Ag |
Diagnosis of diseases associated with signal transduction
|
|
US7662594B2
(en)
|
2002-09-20 |
2010-02-16 |
New England Biolabs, Inc. |
Helicase-dependent amplification of RNA
|
|
AU2004270220B2
(en)
|
2003-09-05 |
2009-03-05 |
The Chinese University Of Hong Kong |
Method for non-invasive prenatal diagnosis
|
|
US20080039413A1
(en)
*
|
2003-10-21 |
2008-02-14 |
Morris David W |
Novel compositions and methods in cancer
|
|
SI3002338T1
(sl)
|
2006-02-02 |
2019-11-29 |
Univ Leland Stanford Junior |
Neinvaziven genetski pregled zarodka z digitalno analizo
|
|
JP2009095262A
(ja)
|
2007-10-15 |
2009-05-07 |
Japan Found Cancer Res |
Znフィンガータンパク質
|
|
CN102301000B
(zh)
|
2008-03-15 |
2015-04-29 |
豪洛捷公司 |
核酸分子扩增反应的分析组分及方法
|
|
EP2233590A1
(en)
*
|
2009-01-28 |
2010-09-29 |
AIT Austrian Institute of Technology GmbH |
Methylation assay
|
|
US20110217297A1
(en)
*
|
2010-03-03 |
2011-09-08 |
Koo Foundation Sun Yat-Sen Cancer Center |
Methods for classifying and treating breast cancers
|
|
US20110256538A1
(en)
*
|
2010-04-15 |
2011-10-20 |
Philadelphia Health & Education Corporation D/B/A Drexel University College Of Medicine |
Epigenomic dna modifications for tissue typing, early cancer detection, and disease management
|
|
US20130237445A1
(en)
*
|
2010-09-14 |
2013-09-12 |
The University Of North Carolina At Chapel Hill |
Methods and kits for detecting melanoma
|
|
US8361720B2
(en)
|
2010-11-15 |
2013-01-29 |
Exact Sciences Corporation |
Real time cleavage assay
|
|
US8715937B2
(en)
|
2010-11-15 |
2014-05-06 |
Exact Sciences Corporation |
Mutation detection assay
|
|
US8916344B2
(en)
|
2010-11-15 |
2014-12-23 |
Exact Sciences Corporation |
Methylation assay
|
|
US20130129668A1
(en)
*
|
2011-09-01 |
2013-05-23 |
The Regents Of The University Of California |
Diagnosis and treatment of arthritis using epigenetics
|
|
WO2013174432A1
(en)
|
2012-05-24 |
2013-11-28 |
Fundació Institut D'investigació Biomèdica De Bellvitge (Idibell) |
Method for the identification of the origin of a cancer of unknown primary origin by methylation analysis
|
|
EP2899274A4
(en)
*
|
2012-09-19 |
2016-06-01 |
Sysmex Corp |
METHOD FOR OBTAINING INFORMATION ON HEPATOCELLULAR CARCINOMAS AND MARKERS AND KIT FOR OBTAINING INFORMATION ON HEPATOCELLULAR CARCINOMAS
|
|
US10233495B2
(en)
*
|
2012-09-27 |
2019-03-19 |
The Hospital For Sick Children |
Methods and compositions for screening and treating developmental disorders
|
|
ES2947873T3
(es)
*
|
2013-03-14 |
2023-08-23 |
Mayo Found Medical Education & Res |
Detección de neoplasias
|
|
JP6369857B2
(ja)
|
2013-05-29 |
2018-08-08 |
シスメックス株式会社 |
肝細胞癌に関する情報の取得方法、ならびに肝細胞癌に関する情報を取得するためのマーカーおよびキット
|
|
CA2938451C
(en)
*
|
2014-01-30 |
2023-10-17 |
The Regents Of The University Of California |
Methylation haplotyping for non-invasive diagnosis (monod)
|
|
US10184154B2
(en)
*
|
2014-09-26 |
2019-01-22 |
Mayo Foundation For Medical Education And Research |
Detecting cholangiocarcinoma
|
|
EP3034624A1
(en)
*
|
2014-12-18 |
2016-06-22 |
Hospital Clínic de Barcelona |
Method for the prognosis of hepatocellular carcinoma
|
|
EP3274440B1
(en)
*
|
2015-03-27 |
2026-03-04 |
Exact Sciences Corporation |
Detecting esophageal disorders
|
|
CN104762301B
(zh)
*
|
2015-04-24 |
2017-12-26 |
武汉大学 |
一种检测肝癌风险基因tspyl5甲基化水平的试剂盒及方法
|
|
JP7481804B2
(ja)
*
|
2016-04-14 |
2024-05-13 |
マヨ ファウンデーション フォア メディカル エデュケーション アンド リサーチ |
高度膵異形成の検出
|