JP2019519470A5 - - Google Patents
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- Publication number
- JP2019519470A5 JP2019519470A5 JP2018552798A JP2018552798A JP2019519470A5 JP 2019519470 A5 JP2019519470 A5 JP 2019519470A5 JP 2018552798 A JP2018552798 A JP 2018552798A JP 2018552798 A JP2018552798 A JP 2018552798A JP 2019519470 A5 JP2019519470 A5 JP 2019519470A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- pharmaceutical composition
- composition according
- antigen
- binding fragment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 claims description 31
- 239000012634 fragment Substances 0.000 claims description 26
- 239000000427 antigen Substances 0.000 claims description 20
- 102000036639 antigens Human genes 0.000 claims description 20
- 108091007433 antigens Proteins 0.000 claims description 20
- 239000008194 pharmaceutical composition Substances 0.000 claims description 16
- 125000003275 alpha amino acid group Chemical group 0.000 claims description 12
- 102000004889 Interleukin-6 Human genes 0.000 claims description 11
- 108090001005 Interleukin-6 Proteins 0.000 claims description 11
- 230000004043 responsiveness Effects 0.000 claims description 8
- 102000010781 Interleukin-6 Receptors Human genes 0.000 claims description 7
- 108010038501 Interleukin-6 Receptors Proteins 0.000 claims description 7
- 239000003795 chemical substances by application Substances 0.000 claims description 5
- 239000012472 biological sample Substances 0.000 claims description 4
- 208000015325 multicentric Castleman disease Diseases 0.000 claims description 4
- 206010039073 rheumatoid arthritis Diseases 0.000 claims description 4
- 230000003001 depressive effect Effects 0.000 claims description 2
- 230000036651 mood Effects 0.000 claims description 2
- 210000002966 serum Anatomy 0.000 claims description 2
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662319558P | 2016-04-07 | 2016-04-07 | |
| US62/319,558 | 2016-04-07 | ||
| PCT/US2017/026395 WO2017177032A2 (en) | 2016-04-07 | 2017-04-06 | Treatment of depression using agents that block binding of il-6 to il-6 receptor |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019519470A JP2019519470A (ja) | 2019-07-11 |
| JP2019519470A5 true JP2019519470A5 (enExample) | 2020-05-07 |
Family
ID=59998986
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018552798A Pending JP2019519470A (ja) | 2016-04-07 | 2017-04-06 | Il−6受容体へのil−6の結合を遮断する薬剤を用いたうつ病の治療 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20170291942A1 (enExample) |
| EP (1) | EP3440108A4 (enExample) |
| JP (1) | JP2019519470A (enExample) |
| AU (1) | AU2017248280A1 (enExample) |
| CA (1) | CA3019828A1 (enExample) |
| MA (1) | MA44631A (enExample) |
| WO (1) | WO2017177032A2 (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2021523138A (ja) * | 2018-05-11 | 2021-09-02 | ヤンセン バイオテツク,インコーポレーテツド | Il−23抗体を使用してうつを治療する方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0214168B8 (pt) * | 2001-11-14 | 2021-05-25 | Centocor Inc | anticorpos anti-il-6, moléculas de ácido nucleico codificando os mesmos, vetores compreendendo as referidas moléculas, composições e formulações compreendendo os referidos anticorpos, bem como métodos de produção dos mesmos |
| PA8672101A1 (es) * | 2005-04-29 | 2006-12-07 | Centocor Inc | Anticuerpos anti-il-6, composiciones, métodos y usos |
| CN102387814A (zh) * | 2009-01-29 | 2012-03-21 | 米迪缪尼有限公司 | 延长体内半衰期的人抗il-6抗体及其在治疗肿瘤、自身免疫性疾病和炎症性疾病中的应用 |
| JP6347477B2 (ja) * | 2013-12-27 | 2018-06-27 | 国立大学法人千葉大学 | 関節リウマチ患者に対する抗il−6受容体抗体治療の有効性予測方法 |
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2017
- 2017-04-06 AU AU2017248280A patent/AU2017248280A1/en not_active Abandoned
- 2017-04-06 MA MA044631A patent/MA44631A/fr unknown
- 2017-04-06 WO PCT/US2017/026395 patent/WO2017177032A2/en not_active Ceased
- 2017-04-06 CA CA3019828A patent/CA3019828A1/en active Pending
- 2017-04-06 EP EP17779843.6A patent/EP3440108A4/en not_active Ceased
- 2017-04-06 JP JP2018552798A patent/JP2019519470A/ja active Pending
- 2017-04-06 US US15/480,924 patent/US20170291942A1/en not_active Abandoned