JP2020508303A5 - - Google Patents

Download PDF

Info

Publication number
JP2020508303A5
JP2020508303A5 JP2019544658A JP2019544658A JP2020508303A5 JP 2020508303 A5 JP2020508303 A5 JP 2020508303A5 JP 2019544658 A JP2019544658 A JP 2019544658A JP 2019544658 A JP2019544658 A JP 2019544658A JP 2020508303 A5 JP2020508303 A5 JP 2020508303A5
Authority
JP
Japan
Prior art keywords
amino acid
seq
acid sequence
antibody
fragment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2019544658A
Other languages
English (en)
Japanese (ja)
Other versions
JP2020508303A (ja
JP6929951B2 (ja
Filing date
Publication date
Priority claimed from PCT/CN2017/074365 external-priority patent/WO2018152687A1/en
Application filed filed Critical
Priority claimed from PCT/CN2018/076940 external-priority patent/WO2018153340A1/en
Publication of JP2020508303A publication Critical patent/JP2020508303A/ja
Publication of JP2020508303A5 publication Critical patent/JP2020508303A5/ja
Application granted granted Critical
Publication of JP6929951B2 publication Critical patent/JP6929951B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2019544658A 2017-02-22 2018-02-22 抗ｌａｇ−３抗体およびその使用 Active JP6929951B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
PCT/CN2017/074365 WO2018152687A1 (en) 2017-02-22 2017-02-22 Anti-lymphocyte activation gene-3 (lag-3) antibodies and uses thereof
CNPCT/CN2017/074365 2017-02-22
CN2017088570 2017-06-16
CNPCT/CN2017/088570 2017-06-16
PCT/CN2018/076940 WO2018153340A1 (en) 2017-02-22 2018-02-22 Anti-lag-3 antibodies and uses thereof

Publications (3)

Publication Number Publication Date
JP2020508303A JP2020508303A (ja) 2020-03-19
JP2020508303A5 true JP2020508303A5 (enExample) 2020-06-25
JP6929951B2 JP6929951B2 (ja) 2021-09-01

Family

ID=63253327

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2019544658A Active JP6929951B2 (ja) 2017-02-22 2018-02-22 抗ｌａｇ−３抗体およびその使用

Country Status (12)

Country Link
US (2) US10577421B2 (enExample)
EP (1) EP3389702A4 (enExample)
JP (1) JP6929951B2 (enExample)
KR (2) KR102236259B1 (enExample)
CN (1) CN109475617B (enExample)
AU (1) AU2018226298B2 (enExample)
CA (1) CA3053989C (enExample)
IL (1) IL268734A (enExample)
NZ (1) NZ756678A (enExample)
SG (1) SG11201907561PA (enExample)
WO (1) WO2018153340A1 (enExample)
ZA (1) ZA201905790B (enExample)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019009728A1 (en) * 2017-07-06 2019-01-10 Merus N.V. ANTIBODIES THAT MODULATE A BIOLOGICAL ACTIVITY EXPRESSED BY A CELL
WO2020038397A1 (en) * 2018-08-21 2020-02-27 I-Mab Anti-pd-l1/anti-lag3 bispecific antibodies and uses thereof
CN110678484B (zh) * 2018-08-21 2022-12-27 天境生物科技(杭州)有限公司 抗pd-l1/抗lag3双特异性抗体及其用途
CN110066334B (zh) * 2019-03-22 2020-03-10 南京医科大学 抗Galectin-3的全人源化单域抗体及应用
CN112010975B (zh) * 2019-05-29 2022-09-13 山东博安生物技术股份有限公司 Lag3结合片段及其用途
CN110320367A (zh) * 2019-05-30 2019-10-11 广州医科大学附属第一医院（广州呼吸中心） 基于lag-3的诊断试剂盒及其在帕金森病诊断产品上的应用
EA202193058A1 (ru) * 2019-06-14 2022-03-05 ЭйБиЭл БИО ИНК. БИСПЕЦИФИЧЕСКОЕ АНТИТЕЛО К -syn/IGF1R И ЕГО ПРИМЕНЕНИЕ
WO2021003739A1 (zh) * 2019-07-11 2021-01-14 武汉友芝友生物制药有限公司 四价对称双特异性抗体
WO2021013215A1 (zh) * 2019-07-23 2021-01-28 南京金斯瑞生物科技有限公司 抗cd47/抗lag-3双特异抗体及其制备方法和应用
CN113004407B (zh) * 2019-12-20 2022-11-11 广东菲鹏制药股份有限公司 Lag3抗体及其应用
CN113348182B (zh) * 2019-12-30 2022-07-12 上海海路生物技术有限公司 Lag-3抗体及其医药用途
WO2021163989A1 (en) * 2020-02-21 2021-08-26 Yinnuolai Biotech Ltd. Anti-baff receptor antibodies and uses thereof
CN116063473A (zh) * 2020-05-19 2023-05-05 益科思特(北京)医药科技发展有限公司 抗新型冠状病毒Spike蛋白抗体及其应用
CN111808192B (zh) * 2020-06-05 2022-02-15 北京天广实生物技术股份有限公司 结合lag3的抗体及其用途
CN112062832B (zh) * 2020-09-24 2021-08-03 河南赛诺特生物技术有限公司 Galectin-3抗原表位肽、抗原、抗体、杂交瘤细胞株及试剂盒
CN115819585B (zh) * 2020-12-10 2023-06-02 北京东方百泰生物科技股份有限公司 一种抗lag-3的单克隆抗体、其抗原结合片段及其应用
MX2023009100A (es) 2021-02-03 2023-09-25 Mozart Therapeutics Inc Agentes aglutinantes y métodos para usar los mismos.
CN115490764B (zh) * 2021-06-18 2025-06-03 佛山热休生物技术有限公司 Lgals3的表位肽及所述表位肽与热休克蛋白的复合物
WO2023076876A1 (en) 2021-10-26 2023-05-04 Mozart Therapeutics, Inc. Modulation of immune responses to viral vectors
WO2023178201A2 (en) * 2022-03-15 2023-09-21 The Board Of Trustees Of The Leland Stanford Junior University Methods of identifying anti-lag-3 agents
CN115819595B (zh) * 2023-01-03 2023-05-16 上海百英生物科技股份有限公司 一种抗lag3纳米抗体及其制备方法与应用
WO2024189628A1 (en) * 2023-03-16 2024-09-19 Technion Research And Development Foundation Limited Lag-3 inhibition for enhanced antiviral immune response
WO2024196072A1 (ko) * 2023-03-20 2024-09-26 경북대학교 산학협력단 Lag-3에 결합하는 펩타이드 및 이의 용도
TW202509063A (zh) * 2023-08-21 2025-03-01 瑞士商百濟神州瑞士有限責任公司 用抗lag3、抗pd-1和化學療法治療食管癌
WO2025128836A1 (en) * 2023-12-13 2025-06-19 Eli Lilly And Company Lag-3 agonist antibodies

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR072999A1 (es) * 2008-08-11 2010-10-06 Medarex Inc Anticuerpos humanos que se unen al gen 3 de activacion linfocitaria (lag-3) y los usos de estos
AR091649A1 (es) * 2012-07-02 2015-02-18 Bristol Myers Squibb Co Optimizacion de anticuerpos que se fijan al gen de activacion de linfocitos 3 (lag-3) y sus usos
SI2970464T1 (sl) * 2013-03-15 2020-08-31 Glaxosmithkline Intellectual Propety Development Limited Anti-LAG-3 vezavni proteini
WO2015085210A1 (en) * 2013-12-06 2015-06-11 Dana-Farber Cancer Institute, Inc. Therapeutic peptides
ME03558B (me) * 2014-03-14 2020-07-20 Novartis Ag Molekuli anti-lag-3 antiтela i njihove upotrebe
JO3663B1 (ar) * 2014-08-19 2020-08-27 Merck Sharp & Dohme الأجسام المضادة لمضاد lag3 وأجزاء ربط الأنتيجين
MA41463A (fr) * 2015-02-03 2017-12-12 Anaptysbio Inc Anticorps dirigés contre le gène d'activation 3 des lymphocytes (lag-3)
TWI773646B (zh) * 2015-06-08 2022-08-11 美商宏觀基因股份有限公司 結合lag-3的分子和其使用方法
AR105444A1 (es) 2015-07-22 2017-10-04 Sorrento Therapeutics Inc Anticuerpos terapéuticos que se unen a la proteína codificada por el gen de activación de linfocitos 3 (lag3)
CN116333138A (zh) * 2015-07-30 2023-06-27 宏观基因有限公司 Pd-1结合分子和其使用方法

Similar Documents

Publication Publication Date Title
JP2020508303A5 (enExample)
JP2017528476A5 (enExample)
JP2020500538A5 (enExample)
JP2018521638A5 (enExample)
AR123305A2 (es) Proteínas de unión a antígeno
IL257281A (en) Anti-pd-1 antibodies and methods of using them
PH12021500002A1 (en) ANTIBODY-SIRPa ANTIBODY
JP2024175003A5 (enExample)
JP2019522961A5 (enExample)
RU2017104815A (ru) Молекулы со специфичностью в отношении cd79 и cd22
RU2588467C3 (ru) Стабильные и растворимые антитела, ингибирующие vegf
JP2015534982A5 (enExample)
PE20090518A1 (es) Proteinas enlazantes de antigenos que enlazan al receptor de la interleucina 18 (il-18)
FI4045533T3 (fi) Ihmisen monoklonaalisia vasta-aineita vakavalle akuutille koronavirus 2 -hengityselinoireyhtymälle (sars-cov-2)
JP2019536806A5 (enExample)
AR080698A1 (es) Anticuerpo o fragmento del mismo que especificamente enlaza la variante de csf -1r humano, composicion farmaceutica que lo comprende, su uso para la manufactura de un medicamento util para el tratamiento de cancer y metodo para determinar si un sujeto es candidato para tratamiento de cancer basado e
IL296682B1 (en) Method for treating or improving metabolic disorders using gastric inhibitory peptide receptor binding proteins in combination with glucagon-like peptide 1 agonists
JP2015508762A5 (enExample)
PE20170687A1 (es) Proteinas de enlace a cd127
JP2010536384A5 (enExample)
AR086579A1 (es) Proteinas de union a antigeno
JP2006512899A5 (enExample)
JP2011528902A5 (enExample)
PE20161033A1 (es) Proteinas de union al antigeno gitr
JP2010516229A5 (enExample)