JP2018507220A5 - - Google Patents
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- Publication number
- JP2018507220A5 JP2018507220A5 JP2017544657A JP2017544657A JP2018507220A5 JP 2018507220 A5 JP2018507220 A5 JP 2018507220A5 JP 2017544657 A JP2017544657 A JP 2017544657A JP 2017544657 A JP2017544657 A JP 2017544657A JP 2018507220 A5 JP2018507220 A5 JP 2018507220A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- amino acid
- acid sequence
- antagonistic
- set forth
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562118350P | 2015-02-19 | 2015-02-19 | |
| US62/118,350 | 2015-02-19 | ||
| US201562150235P | 2015-04-20 | 2015-04-20 | |
| US62/150,235 | 2015-04-20 | ||
| PCT/US2016/018634 WO2016134234A1 (en) | 2015-02-19 | 2016-02-19 | Methods, compositions, and kits for treatment of cancer |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020167443A Division JP7122357B2 (ja) | 2015-02-19 | 2020-10-02 | がんの治療のための方法、組成物、及びキット |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018507220A JP2018507220A (ja) | 2018-03-15 |
| JP2018507220A5 true JP2018507220A5 (enExample) | 2019-04-04 |
| JP6774421B2 JP6774421B2 (ja) | 2020-10-21 |
Family
ID=56689191
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017544657A Expired - Fee Related JP6774421B2 (ja) | 2015-02-19 | 2016-02-19 | がんの治療のための方法、組成物、及びキット |
| JP2020167443A Expired - Fee Related JP7122357B2 (ja) | 2015-02-19 | 2020-10-02 | がんの治療のための方法、組成物、及びキット |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020167443A Expired - Fee Related JP7122357B2 (ja) | 2015-02-19 | 2020-10-02 | がんの治療のための方法、組成物、及びキット |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20160243228A1 (enExample) |
| EP (1) | EP3258966A4 (enExample) |
| JP (2) | JP6774421B2 (enExample) |
| KR (1) | KR20170137717A (enExample) |
| CN (1) | CN107635583A (enExample) |
| AU (2) | AU2016219917B2 (enExample) |
| BR (1) | BR112017017700A2 (enExample) |
| CA (1) | CA2976638A1 (enExample) |
| IL (1) | IL253979B (enExample) |
| MX (1) | MX2017010595A (enExample) |
| SG (1) | SG11201706727XA (enExample) |
| WO (1) | WO2016134234A1 (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2549769T3 (es) | 2009-03-25 | 2015-11-02 | Genentech, Inc. | Anticuerpos anti-FGFR3 y métodos que emplean los mismos |
| GB201007286D0 (en) | 2010-04-30 | 2010-06-16 | Astex Therapeutics Ltd | New compounds |
| GB201209613D0 (en) | 2012-05-30 | 2012-07-11 | Astex Therapeutics Ltd | New compounds |
| US10736900B2 (en) | 2014-03-26 | 2020-08-11 | Astex Therapeutics Ltd | Combinations of an FGFR inhibitor and an IGF1R inhibitor |
| BR112016022056B1 (pt) | 2014-03-26 | 2023-04-11 | Astex Therapeutics Limited | Combinação, composição farmacêutica, uso de uma combinação ou uma composição farmacêutica, e, produto farmacêutico |
| JO3512B1 (ar) | 2014-03-26 | 2020-07-05 | Astex Therapeutics Ltd | مشتقات كينوكسالين مفيدة كمعدلات لإنزيم fgfr كيناز |
| TWI719960B (zh) | 2015-02-10 | 2021-03-01 | 英商阿斯迪克治療公司 | 新穎組成物 |
| US10478494B2 (en) * | 2015-04-03 | 2019-11-19 | Astex Therapeutics Ltd | FGFR/PD-1 combination therapy for the treatment of cancer |
| HUE050567T2 (hu) | 2015-09-23 | 2020-12-28 | Janssen Pharmaceutica Nv | Triciklusos heterociklusok rák kezelésére |
| WO2017050865A1 (en) | 2015-09-23 | 2017-03-30 | Janssen Pharmaceutica Nv | Bi-heteroaryl substituted 1,4-benzodiazepines and uses thereof for the treatment of cancer |
| AU2016374441B2 (en) | 2015-12-17 | 2021-10-21 | Eisai R&D Management Co., Ltd. | Therapeutic agent for breast cancer |
| CN110785184A (zh) * | 2017-02-06 | 2020-02-11 | 雷尼尔医疗公司 | 用于治疗癌症的方法，组合物和试剂盒 |
| CN108440673B (zh) * | 2018-04-08 | 2021-08-17 | 海南医学院 | Fc融合蛋白PD1/FGFR1及其应用 |
| US20200277387A1 (en) * | 2019-03-01 | 2020-09-03 | Rainier Therapeutics, Inc. | Methods and compositions for treating cancer |
| JP2023514795A (ja) * | 2019-06-03 | 2023-04-11 | フュージョン ファーマシューティカルズ インコーポレイテッド | がんを処置するための方法および組成物 |
| US20220348662A1 (en) * | 2019-09-26 | 2022-11-03 | Janssen Pharmaceutica Nv | Use of fgfr inhibitors in fgfr-genetically altered cancers to enhance patient response to immune checkpoint inhibitors in sequential treatment settings |
| KR20220157464A (ko) * | 2020-03-23 | 2022-11-29 | 퓨전 파마슈티칼즈 인크. | Fgfr3-표적화된 방사선면역접합체 및 그의 용도 |
| TW202229343A (zh) | 2020-08-21 | 2022-08-01 | 美商健臻公司 | Fgfr3抗體及使用方法 |
| WO2022092085A1 (ja) * | 2020-10-28 | 2022-05-05 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 腫瘍治療用医薬組成物 |
| CN121002062A (zh) | 2023-01-13 | 2025-11-21 | 再生元制药公司 | Fgfr3结合分子及其使用方法 |
| WO2025240335A1 (en) | 2024-05-13 | 2025-11-20 | Regeneron Pharmaceuticals, Inc. | Fgfr3 binding molecules and methods of use thereof |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR073770A1 (es) * | 2008-10-20 | 2010-12-01 | Imclone Llc | Anticuerpo aislado que se enlaza especificamente con, e induce la degradacion del receptor-3 del factor de crecimiento del fibroblasto humano (fgfr-3), fragmento de enlace fgfr-3 humano del mismo, composicion farmaceutica y producto que lo comprenden |
| ES2549769T3 (es) * | 2009-03-25 | 2015-11-02 | Genentech, Inc. | Anticuerpos anti-FGFR3 y métodos que emplean los mismos |
| WO2012088266A2 (en) * | 2010-12-22 | 2012-06-28 | Incyte Corporation | Substituted imidazopyridazines and benzimidazoles as inhibitors of fgfr3 |
| AR091649A1 (es) * | 2012-07-02 | 2015-02-18 | Bristol Myers Squibb Co | Optimizacion de anticuerpos que se fijan al gen de activacion de linfocitos 3 (lag-3) y sus usos |
| BR112015001724A2 (pt) * | 2012-07-27 | 2018-04-03 | Genentech Inc | métodos de tratamento de condições relacionadas a fgfr3 |
| TWI888366B (zh) * | 2013-07-16 | 2025-07-01 | 美商建南德克公司 | 利用pd-1軸結合拮抗劑及tigit抑制劑治療癌症之方法 |
-
2016
- 2016-02-19 SG SG11201706727XA patent/SG11201706727XA/en unknown
- 2016-02-19 CA CA2976638A patent/CA2976638A1/en active Pending
- 2016-02-19 AU AU2016219917A patent/AU2016219917B2/en active Active
- 2016-02-19 BR BR112017017700A patent/BR112017017700A2/pt not_active Application Discontinuation
- 2016-02-19 MX MX2017010595A patent/MX2017010595A/es unknown
- 2016-02-19 CN CN201680022780.7A patent/CN107635583A/zh active Pending
- 2016-02-19 KR KR1020177025882A patent/KR20170137717A/ko not_active Ceased
- 2016-02-19 WO PCT/US2016/018634 patent/WO2016134234A1/en not_active Ceased
- 2016-02-19 US US15/048,030 patent/US20160243228A1/en not_active Abandoned
- 2016-02-19 JP JP2017544657A patent/JP6774421B2/ja not_active Expired - Fee Related
- 2016-02-19 EP EP16753128.4A patent/EP3258966A4/en not_active Withdrawn
-
2017
- 2017-08-14 IL IL253979A patent/IL253979B/en active IP Right Grant
-
2020
- 2020-10-02 JP JP2020167443A patent/JP7122357B2/ja not_active Expired - Fee Related
-
2022
- 2022-01-13 AU AU2022200196A patent/AU2022200196B2/en not_active Expired - Fee Related
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