IL253979B - Methods, preparations and kits for cancer treatment - Google Patents
Methods, preparations and kits for cancer treatmentInfo
- Publication number
- IL253979B IL253979B IL253979A IL25397917A IL253979B IL 253979 B IL253979 B IL 253979B IL 253979 A IL253979 A IL 253979A IL 25397917 A IL25397917 A IL 25397917A IL 253979 B IL253979 B IL 253979B
- Authority
- IL
- Israel
- Prior art keywords
- kits
- cancer
- compositions
- treatment
- methods
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title 1
- 201000011510 cancer Diseases 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2818—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- A61K2039/507—Comprising a combination of two or more separate antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562118350P | 2015-02-19 | 2015-02-19 | |
| US201562150235P | 2015-04-20 | 2015-04-20 | |
| PCT/US2016/018634 WO2016134234A1 (en) | 2015-02-19 | 2016-02-19 | Methods, compositions, and kits for treatment of cancer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL253979A0 IL253979A0 (en) | 2017-10-31 |
| IL253979B true IL253979B (en) | 2021-06-30 |
Family
ID=56689191
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL253979A IL253979B (en) | 2015-02-19 | 2017-08-14 | Methods, preparations and kits for cancer treatment |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20160243228A1 (enExample) |
| EP (1) | EP3258966A4 (enExample) |
| JP (2) | JP6774421B2 (enExample) |
| KR (1) | KR20170137717A (enExample) |
| CN (1) | CN107635583A (enExample) |
| AU (2) | AU2016219917B2 (enExample) |
| BR (1) | BR112017017700A2 (enExample) |
| CA (1) | CA2976638A1 (enExample) |
| IL (1) | IL253979B (enExample) |
| MX (1) | MX2017010595A (enExample) |
| SG (1) | SG11201706727XA (enExample) |
| WO (1) | WO2016134234A1 (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8410250B2 (en) | 2009-03-25 | 2013-04-02 | Genentech, Inc. | Anti-FGFR3 antibodies and methods using same |
| GB201007286D0 (en) | 2010-04-30 | 2010-06-16 | Astex Therapeutics Ltd | New compounds |
| GB201209613D0 (en) | 2012-05-30 | 2012-07-11 | Astex Therapeutics Ltd | New compounds |
| JO3512B1 (ar) | 2014-03-26 | 2020-07-05 | Astex Therapeutics Ltd | مشتقات كينوكسالين مفيدة كمعدلات لإنزيم fgfr كيناز |
| PT3122358T (pt) | 2014-03-26 | 2021-03-04 | Astex Therapeutics Ltd | Combinações de inibidores do fgfr e cmet para o tratamento do cancro |
| EP3122359B1 (en) | 2014-03-26 | 2020-12-16 | Astex Therapeutics Ltd. | Combinations of an fgfr inhibitor and an igf1r inhibitor |
| JOP20200201A1 (ar) | 2015-02-10 | 2017-06-16 | Astex Therapeutics Ltd | تركيبات صيدلانية تشتمل على n-(3.5- ثنائي ميثوكسي فينيل)-n'-(1-ميثيل إيثيل)-n-[3-(ميثيل-1h-بيرازول-4-يل) كينوكسالين-6-يل]إيثان-1.2-ثنائي الأمين |
| US10478494B2 (en) | 2015-04-03 | 2019-11-19 | Astex Therapeutics Ltd | FGFR/PD-1 combination therapy for the treatment of cancer |
| CN108026095B (zh) | 2015-09-23 | 2021-07-27 | 詹森药业有限公司 | 新化合物 |
| HRP20220012T1 (hr) | 2015-09-23 | 2022-04-01 | Janssen Pharmaceutica Nv | Bi-heteroaril supstituirani 1,4-benzodiazepini i njihova upotreba za liječenje raka |
| KR102486722B1 (ko) | 2015-12-17 | 2023-01-11 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 유방암 치료제 |
| KR20200026787A (ko) * | 2017-02-06 | 2020-03-11 | 레이니어 테라퓨틱스, 인크. | 암 치료를 위한 방법, 조성물, 및 키트 |
| CN108440673B (zh) * | 2018-04-08 | 2021-08-17 | 海南医学院 | Fc融合蛋白PD1/FGFR1及其应用 |
| US20200277387A1 (en) * | 2019-03-01 | 2020-09-03 | Rainier Therapeutics, Inc. | Methods and compositions for treating cancer |
| JP2023514795A (ja) * | 2019-06-03 | 2023-04-11 | フュージョン ファーマシューティカルズ インコーポレイテッド | がんを処置するための方法および組成物 |
| JP7709959B2 (ja) * | 2019-09-26 | 2025-07-17 | ヤンセン ファーマシューティカ エヌ．ベー． | 連続的な治療設定における免疫チェックポイント阻害剤に対する患者の応答を高めるためのｆｇｆｒ遺伝子改変癌におけるｆｇｆｒ阻害剤の使用 |
| US20230201384A1 (en) * | 2020-03-23 | 2023-06-29 | Fusion Pharmaceuticals Inc. | Fgfr3-targeted radioimmunoconjugates and uses thereof |
| CA3189470A1 (en) | 2020-08-21 | 2022-02-24 | Yves SABBAGH | Fgfr3 antibodies and methods of use |
| CN116390757A (zh) * | 2020-10-28 | 2023-07-04 | 卫材R&D管理有限公司 | 用于治疗肿瘤的药物组合物 |
| KR20250148746A (ko) | 2023-01-13 | 2025-10-14 | 리제너론 파아마슈티컬스, 인크. | Fgfr3 결합 분자 및 그의 사용 방법 |
| WO2025240335A1 (en) | 2024-05-13 | 2025-11-20 | Regeneron Pharmaceuticals, Inc. | Fgfr3 binding molecules and methods of use thereof |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR073770A1 (es) * | 2008-10-20 | 2010-12-01 | Imclone Llc | Anticuerpo aislado que se enlaza especificamente con, e induce la degradacion del receptor-3 del factor de crecimiento del fibroblasto humano (fgfr-3), fragmento de enlace fgfr-3 humano del mismo, composicion farmaceutica y producto que lo comprenden |
| US8410250B2 (en) * | 2009-03-25 | 2013-04-02 | Genentech, Inc. | Anti-FGFR3 antibodies and methods using same |
| US8754114B2 (en) * | 2010-12-22 | 2014-06-17 | Incyte Corporation | Substituted imidazopyridazines and benzimidazoles as inhibitors of FGFR3 |
| AR091649A1 (es) * | 2012-07-02 | 2015-02-18 | Bristol Myers Squibb Co | Optimizacion de anticuerpos que se fijan al gen de activacion de linfocitos 3 (lag-3) y sus usos |
| US20140030259A1 (en) * | 2012-07-27 | 2014-01-30 | Genentech, Inc. | Methods of treating fgfr3 related conditions |
| BR112016000853A2 (pt) * | 2013-07-16 | 2017-12-12 | Genentech Inc | métodos para tratar ou retardar, reduzir ou inibir a recidiva ou a progressão do câncer e a progressão de uma doença imune-relacionada em um indivíduo, para aumentar, melhorar ou estimular uma resposta ou função imune em um indivíduo e kit |
-
2016
- 2016-02-19 WO PCT/US2016/018634 patent/WO2016134234A1/en not_active Ceased
- 2016-02-19 CA CA2976638A patent/CA2976638A1/en active Pending
- 2016-02-19 EP EP16753128.4A patent/EP3258966A4/en not_active Withdrawn
- 2016-02-19 SG SG11201706727XA patent/SG11201706727XA/en unknown
- 2016-02-19 AU AU2016219917A patent/AU2016219917B2/en active Active
- 2016-02-19 US US15/048,030 patent/US20160243228A1/en not_active Abandoned
- 2016-02-19 BR BR112017017700A patent/BR112017017700A2/pt not_active Application Discontinuation
- 2016-02-19 MX MX2017010595A patent/MX2017010595A/es unknown
- 2016-02-19 KR KR1020177025882A patent/KR20170137717A/ko not_active Ceased
- 2016-02-19 CN CN201680022780.7A patent/CN107635583A/zh active Pending
- 2016-02-19 JP JP2017544657A patent/JP6774421B2/ja active Active
-
2017
- 2017-08-14 IL IL253979A patent/IL253979B/en active IP Right Grant
-
2020
- 2020-10-02 JP JP2020167443A patent/JP7122357B2/ja active Active
-
2022
- 2022-01-13 AU AU2022200196A patent/AU2022200196B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| BR112017017700A2 (pt) | 2018-07-31 |
| JP2021020909A (ja) | 2021-02-18 |
| WO2016134234A1 (en) | 2016-08-25 |
| EP3258966A1 (en) | 2017-12-27 |
| AU2016219917A1 (en) | 2017-09-07 |
| JP2018507220A (ja) | 2018-03-15 |
| NZ735243A (en) | 2024-11-29 |
| AU2022200196B2 (en) | 2025-04-10 |
| SG11201706727XA (en) | 2017-09-28 |
| JP7122357B2 (ja) | 2022-08-19 |
| AU2016219917B2 (en) | 2021-12-16 |
| CA2976638A1 (en) | 2016-08-25 |
| KR20170137717A (ko) | 2017-12-13 |
| CN107635583A (zh) | 2018-01-26 |
| IL253979A0 (en) | 2017-10-31 |
| MX2017010595A (es) | 2018-11-12 |
| JP6774421B2 (ja) | 2020-10-21 |
| EP3258966A4 (en) | 2018-07-25 |
| US20160243228A1 (en) | 2016-08-25 |
| AU2022200196A1 (en) | 2022-02-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted |