JP2019516757A5 - - Google Patents
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- JP2019516757A5 JP2019516757A5 JP2018561543A JP2018561543A JP2019516757A5 JP 2019516757 A5 JP2019516757 A5 JP 2019516757A5 JP 2018561543 A JP2018561543 A JP 2018561543A JP 2018561543 A JP2018561543 A JP 2018561543A JP 2019516757 A5 JP2019516757 A5 JP 2019516757A5
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- Japan
- Prior art keywords
- compound
- alkyl
- membered
- oxo
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022164864A JP2023002643A (ja) | 2016-05-24 | 2022-10-13 | Ｃｂｐ／ｅｐ３００の複素環式インヒビターおよびがんの処置におけるそれらの使用 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNPCT/CN2016/083124 | 2016-05-24 | ||
| CN2016083124 | 2016-05-24 | ||
| PCT/US2017/034320 WO2017205536A2 (en) | 2016-05-24 | 2017-05-24 | Therapeutic compounds and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022164864A Division JP2023002643A (ja) | 2016-05-24 | 2022-10-13 | Ｃｂｐ／ｅｐ３００の複素環式インヒビターおよびがんの処置におけるそれらの使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019516757A JP2019516757A (ja) | 2019-06-20 |
| JP2019516757A5 true JP2019516757A5 (https=) | 2020-07-09 |
| JP7160688B2 JP7160688B2 (ja) | 2022-10-25 |
Family
ID=59014798
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018561543A Active JP7160688B2 (ja) | 2016-05-24 | 2017-05-24 | Ｃｂｐ／ｅｐ３００の複素環式インヒビターおよびがんの処置におけるそれらの使用 |
| JP2022164864A Pending JP2023002643A (ja) | 2016-05-24 | 2022-10-13 | Ｃｂｐ／ｅｐ３００の複素環式インヒビターおよびがんの処置におけるそれらの使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022164864A Pending JP2023002643A (ja) | 2016-05-24 | 2022-10-13 | Ｃｂｐ／ｅｐ３００の複素環式インヒビターおよびがんの処置におけるそれらの使用 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US10696655B2 (https=) |
| EP (2) | EP3464270B1 (https=) |
| JP (2) | JP7160688B2 (https=) |
| CN (2) | CN115028617A (https=) |
| MA (1) | MA45122A (https=) |
| WO (1) | WO2017205536A2 (https=) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4014967A1 (en) | 2016-04-29 | 2022-06-22 | Icahn School of Medicine at Mount Sinai | Targeting the innate immunesystem to induce long-term tolerance and to resolve macrophage accumulation in atherosclerosis |
| MA45122A (fr) | 2016-05-24 | 2019-04-10 | Constellation Pharmaceuticals Inc | Inhibiteurs hétérocycliques de cbp/ep300 et leur utilisation dans le traitement du cancer |
| ES2928773T3 (es) | 2017-01-17 | 2022-11-22 | Heparegenix Gmbh | Inhibidores de proteína cinasas para fomentar la regeneración hepática o reducir o prevenir la muerte de hepatocitos |
| WO2019000682A1 (zh) * | 2017-06-30 | 2019-01-03 | 北京泰德制药股份有限公司 | Rho相关蛋白激酶抑制剂、包含其的药物组合物及其制备方法和用途 |
| CN110582489B (zh) * | 2017-06-30 | 2023-10-27 | 北京泰德制药股份有限公司 | Rho相关蛋白激酶抑制剂、包含其的药物组合物及其制备方法和用途 |
| US10323023B2 (en) | 2017-06-30 | 2019-06-18 | Beijing Tide Pharmaceutical Co., Ltd. | Rho-associated protein kinase inhibitor, pharmaceutical composition comprising the same, as well as preparation method and use thereof |
| US11292791B2 (en) | 2017-09-15 | 2022-04-05 | Forma Therapeutics, Inc. | Tetrahydro-imidazo quinoline compositions as CBP/P300 inhibitors |
| WO2019161157A1 (en) * | 2018-02-16 | 2019-08-22 | Constellation Pharmceuticals, Inc. | P300/cbp hat inhibitors |
| DK3752497T3 (da) * | 2018-02-16 | 2024-09-30 | Constellation Pharmaceuticals Inc | P300/cbp-hat-hæmmere |
| AU2019245403B2 (en) * | 2018-03-29 | 2025-02-06 | Board Of Regents, The University Of Texas System | Imidazopiperazine inhibitors of transcription activating proteins |
| WO2019195846A1 (en) | 2018-04-06 | 2019-10-10 | Board Of Regents, The University Of Texas System | Imidazopiperazinone inhibitors of transcription activating proteins |
| WO2019201291A1 (zh) * | 2018-04-20 | 2019-10-24 | 中国科学院上海药物研究所 | 组蛋白乙酰转移酶(hat)抑制剂及其用途 |
| EP3793521A4 (en) | 2018-05-18 | 2022-02-23 | Janssen Biotech, Inc. | SAFE AND EFFECTIVE METHOD OF TREATING LUPUS WITH AN ANTI-IL12/IL23 ANTIBODY |
| IL279734B2 (en) | 2018-06-29 | 2024-11-01 | Forma Therapeutics Inc | Inhibiting creb binding protein (cbp) |
| US11420977B2 (en) | 2018-08-02 | 2022-08-23 | Trustees Of Boston University | Late SV40 (LSF) inhibitors |
| CN109336836A (zh) * | 2018-11-23 | 2019-02-15 | 厦门大学 | Carm1小分子抑制剂的化合物及用途 |
| CN113646002A (zh) * | 2019-02-27 | 2021-11-12 | 上海睿跃生物科技有限公司 | 环amp反应元件结合蛋白(cbp)和/或300kda腺病毒e1a结合蛋白(p300)降解化合物和使用方法 |
| SMT202400386T1 (it) * | 2019-02-27 | 2024-11-15 | Constellation Pharmaceuticals Inc | Derivati di n-(piridinil)acetammide come inibitori di hat p300/cbp e metodi per il loro utilizzo |
| US12351577B2 (en) | 2019-03-15 | 2025-07-08 | Forma Therapeutics, Inc. | Inhibiting cyclic AMP-responsive element-binding protein (CREB) |
| CN111763180B (zh) * | 2019-04-02 | 2023-06-09 | 中国医学科学院药物研究所 | 苯并氮杂环类化合物及其制法和药物用途 |
| TW202120095A (zh) * | 2019-08-05 | 2021-06-01 | 美商美國禮來大藥廠 | 7,8-二氫-4H-吡唑并[4,3-c]氮呯-6-酮化合物 |
| CN114761013A (zh) | 2019-09-27 | 2022-07-15 | 迪斯克医药公司 | 治疗骨髓纤维化和相关病症的方法 |
| CN112574189B (zh) * | 2019-09-27 | 2024-05-31 | 海创药业股份有限公司 | 一种ep300/cbp抑制剂 |
| WO2021150835A1 (en) * | 2020-01-24 | 2021-07-29 | Trustees Of Boston University | Heterocyclic lsf inhibitors and their uses |
| AU2021259814B2 (en) * | 2020-04-25 | 2023-09-28 | Pharmablock Sciences (Nanjing), Inc. | CBP/EP300 inhibitor and use thereof |
| WO2021231798A1 (en) | 2020-05-13 | 2021-11-18 | Disc Medicine, Inc. | Anti-hemojuvelin (hjv) antibodies for treating myelofibrosis |
| US11458132B2 (en) | 2020-09-01 | 2022-10-04 | Trustees Of Boston University | Quinolin-2(1H)-one inhibitors of Late SV40 Factor |
| IL301225A (en) * | 2020-09-09 | 2023-05-01 | Aurigene Oncology Ltd | Heterocyclic compounds as CBP/EP300 bromodomain inhibitors |
| US11801243B2 (en) | 2020-09-23 | 2023-10-31 | Forma Therapeutics, Inc. | Bromodomain inhibitors for androgen receptor-driven cancers |
| US11795168B2 (en) | 2020-09-23 | 2023-10-24 | Forma Therapeutics, Inc. | Inhibiting cyclic amp-responsive element-binding protein (CREB) binding protein (CBP) |
| WO2022072648A1 (en) | 2020-10-02 | 2022-04-07 | Board Of Regents, The University Of Texas System | Imidazopiperazine inhibitors of transcription activating proteins |
| JP7777131B2 (ja) | 2020-10-02 | 2025-11-27 | ボード オブ レジェンツ，ザ ユニバーシティ オブ テキサス システム | 転写活性化タンパク質のイミダゾピペラジン阻害剤 |
| CN118459539B (zh) * | 2021-03-19 | 2026-01-06 | 生物治疗探索股份有限公司 | 用于调节训练免疫的化合物及其使用方法 |
| CN113087683B (zh) * | 2021-03-22 | 2022-04-22 | 华南理工大学 | 氮取代苯并噻唑啉酮类xor/urat1双重抑制剂及其制备方法与应用 |
| TW202409023A (zh) | 2022-07-14 | 2024-03-01 | 美商富曼西公司 | 除草苯并𠯤 |
| CN117843618A (zh) * | 2022-08-29 | 2024-04-09 | 北京沐华生物科技有限责任公司 | 一种ep300/cbp调节剂及其制备方法和用途 |
| TW202515547A (zh) * | 2023-08-30 | 2025-04-16 | 美商昂科皮治療公司亦以Ｓｋ生命科學實驗室名稱營業 | 作為ｃｂｐ／ｐ３００降解劑之化合物及組合物以及其用途 |
| WO2025111184A1 (en) | 2023-11-21 | 2025-05-30 | Fmc Corporation | Substituted tetrahydroquinoline and tetrahydroquinoxaline herbicides |
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| AR108326A1 (es) * | 2016-04-27 | 2018-08-08 | Samumed Llc | Isoquinolin-3-il carboxamidas y preparación y uso de las mismas |
| AR108325A1 (es) * | 2016-04-27 | 2018-08-08 | Samumed Llc | Isoquinolin-3-il carboxamidas y preparación y uso de las mismas |
| MA45122A (fr) | 2016-05-24 | 2019-04-10 | Constellation Pharmaceuticals Inc | Inhibiteurs hétérocycliques de cbp/ep300 et leur utilisation dans le traitement du cancer |
-
2017
- 2017-05-24 MA MA045122A patent/MA45122A/fr unknown
- 2017-05-24 CN CN202210701205.7A patent/CN115028617A/zh active Pending
- 2017-05-24 EP EP17728375.1A patent/EP3464270B1/en active Active
- 2017-05-24 CN CN201780045651.4A patent/CN109476641B/zh active Active
- 2017-05-24 EP EP22152776.5A patent/EP4067347B1/en active Active
- 2017-05-24 JP JP2018561543A patent/JP7160688B2/ja active Active
- 2017-05-24 WO PCT/US2017/034320 patent/WO2017205536A2/en not_active Ceased
-
2018
- 2018-11-21 US US16/198,597 patent/US10696655B2/en active Active
-
2020
- 2020-05-28 US US16/886,541 patent/US11168070B2/en not_active Expired - Fee Related
-
2022
- 2022-10-13 JP JP2022164864A patent/JP2023002643A/ja active Pending
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