JP2019516665A5 - - Google Patents

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Publication number
JP2019516665A5
JP2019516665A5 JP2018546587A JP2018546587A JP2019516665A5 JP 2019516665 A5 JP2019516665 A5 JP 2019516665A5 JP 2018546587 A JP2018546587 A JP 2018546587A JP 2018546587 A JP2018546587 A JP 2018546587A JP 2019516665 A5 JP2019516665 A5 JP 2019516665A5
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JP
Japan
Prior art keywords
polypeptide
terminal
mhc
multimeric
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2018546587A
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English (en)
Japanese (ja)
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JP2019516665A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2017/020276 external-priority patent/WO2017151818A2/en
Publication of JP2019516665A publication Critical patent/JP2019516665A/ja
Publication of JP2019516665A5 publication Critical patent/JP2019516665A5/ja
Pending legal-status Critical Current

Links

JP2018546587A 2016-03-02 2017-03-01 T細胞調節多量体ポリペプチド及びその使用方法 Pending JP2019516665A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662302654P 2016-03-02 2016-03-02
US62/302,654 2016-03-02
PCT/US2017/020276 WO2017151818A2 (en) 2016-03-02 2017-03-01 T-cell modulatory multimeric polypeptides and methods of use thereof

Publications (2)

Publication Number Publication Date
JP2019516665A JP2019516665A (ja) 2019-06-20
JP2019516665A5 true JP2019516665A5 (enExample) 2020-04-09

Family

ID=59743228

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2018546587A Pending JP2019516665A (ja) 2016-03-02 2017-03-01 T細胞調節多量体ポリペプチド及びその使用方法

Country Status (9)

Country Link
US (2) US20190062400A1 (enExample)
EP (1) EP3423108A4 (enExample)
JP (1) JP2019516665A (enExample)
KR (1) KR20180132663A (enExample)
CN (1) CN109311945A (enExample)
AU (1) AU2017226269B2 (enExample)
CA (1) CA3014458A1 (enExample)
IL (1) IL261401A (enExample)
WO (1) WO2017151818A2 (enExample)

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JP2016500255A (ja) 2012-12-11 2016-01-12 アルバート アインシュタイン カレッジ オブ メディシン オブ イエシバ ユニバーシティ ハイスループットなレセプター:リガンド同定の方法
EP3283508B1 (en) 2015-04-17 2021-03-17 Alpine Immune Sciences, Inc. Immunomodulatory proteins with tunable affinities
CA3001131A1 (en) 2015-11-02 2017-05-11 Five Prime Therapeutics, Inc. Cd80 extracellular domain polypeptides and their use in cancer treatment
US11078282B2 (en) 2016-04-15 2021-08-03 Alpine Immune Sciences, Inc. CD80 variant immunomodulatory proteins and uses thereof
US11339201B2 (en) 2016-05-18 2022-05-24 Albert Einstein College Of Medicine Variant PD-L1 polypeptides, T-cell modulatory multimeric polypeptides, and methods of use thereof
JP7071288B2 (ja) 2016-05-18 2022-05-18 キュー バイオファーマ, インコーポレイテッド T細胞調節多量体ポリペプチド及びその使用方法
MX2019007611A (es) 2016-12-22 2020-07-29 Cue Biopharma Inc Polipéptidos multiméricos moduladores de linfocitos t y métodos para su uso.
EP3565829A4 (en) 2017-01-09 2021-01-27 Cue Biopharma, Inc. T-CELL-MODULATING MULTIMERIC POLYPEPTIDES AND METHOD OF USING THEREOF
CN118453840A (zh) 2017-03-15 2024-08-09 库尔生物制药有限公司 用于调节免疫应答的方法
CN110662758A (zh) 2017-03-16 2020-01-07 高山免疫科学股份有限公司 Cd80变体免疫调节蛋白及其用途
CA3057866A1 (en) 2017-04-28 2018-11-01 Five Prime Therapeutics, Inc. Methods of treatment with cd80 extracellular domain polypeptides
CA3074839A1 (en) * 2017-09-07 2019-03-14 Cue Biopharma, Inc. T-cell modulatory multimeric polypeptide with conjugation sites and methods of use thereof
AU2018328283A1 (en) * 2017-09-07 2020-02-20 Cue Biopharma, Inc. Antigen-presenting polypeptides and methods of use thereof
WO2019139896A1 (en) 2018-01-09 2019-07-18 Cue Biopharma, Inc. Multimeric t-cell modulatory polypeptides and methods of use thereof
WO2020132368A1 (en) * 2018-12-19 2020-06-25 Cue Biopharma, Inc. T-cell modulatory multimeric polypeptides with conjugation sites and methods of use thereof
WO2020181272A1 (en) * 2019-03-06 2020-09-10 Cue Biopharma, Inc. Antigen-presenting polypeptides with chemical conjugation sites and methods of use thereof
WO2020243315A1 (en) * 2019-05-29 2020-12-03 Cue Biopharma, Inc. Multimeric t-cell modulatory polypeptides and methods of use thereof
WO2021055594A1 (en) * 2019-09-20 2021-03-25 Cue Biopharma, Inc. T-cell modulatory polypeptides and methods of use thereof
TW202130655A (zh) 2019-10-23 2021-08-16 美商庫爾生物製藥有限公司 TGF—β多肽
WO2021178975A1 (en) * 2020-03-06 2021-09-10 Albert Einstein College Of Medicine A method to generate chimeric antigen receptor (car) t-cells (car-t cells) from pathogen-specific cytotoxic lymphocytes to enable the subsequent in vivo modulation of their functional activity
WO2021181233A2 (en) * 2020-03-09 2021-09-16 Pfizer Inc. Fusion proteins and uses thereof
TW202208395A (zh) 2020-05-12 2022-03-01 美商信號生物製藥公司 多聚體t細胞調節多肽及其使用方法
EP4157350A4 (en) * 2020-05-26 2025-07-23 Cue Biopharma Inc ANTIGEN-PRESENTING POLYPEPTIDE COMPLEXES AND METHODS OF USE THEREOF
WO2021242935A1 (en) * 2020-05-26 2021-12-02 Cue Biopharma, Inc. Antigen presenting polypeptide complexes and methods of use thereof
IL299834A (en) * 2020-07-14 2023-03-01 Cue Biopharma Inc with binding sites and methods for using them T - cellular modulatory polypeptides
JP2023541366A (ja) 2020-09-09 2023-10-02 キュー バイオファーマ, インコーポレイテッド 1型真性糖尿病(t1d)を治療するためのmhcクラスii t細胞調節多量体ポリペプチド及びその使用方法
CA3216273A1 (en) * 2021-04-21 2022-10-27 Ronald D. SEIDEL III Antigen presenting polypeptide complexes bearing tgf-beta and methods of use thereof
US20240270815A1 (en) * 2021-05-26 2024-08-15 Cue Biopharma, Inc. Antigen Presenting Polypeptide Complexes and Methods of Use Thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9909472A (pt) * 1998-04-07 2001-09-11 Corixa Corp Polipeptìdeo purificado, processo para prevenir tuberculose, e, composição farmacêutica
CN107988156B (zh) * 2011-06-30 2022-01-04 建新公司 T细胞活化的抑制剂
CN102898504B (zh) * 2012-10-23 2014-08-06 中国农业大学 抗氧化活性合成肽及其用途
JP6652932B2 (ja) * 2014-06-18 2020-02-26 アルバート アインシュタイン カレッジ オブ メディシン synTacポリペプチド及びその使用

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