KR20180132663A - T-세포 조절 다량체 폴리펩타이드 및 이의 사용 방법 - Google Patents
T-세포 조절 다량체 폴리펩타이드 및 이의 사용 방법 Download PDFInfo
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| BR112015013557B1 (pt) | 2012-12-11 | 2021-12-14 | Albert Einstein College Of Medicine | Sistema, método, método para determinar o efeito de um resíduo de aminoácido predeterminado de uma primeira proteína sobre a ligação da primeira proteína a uma segunda proteína e polipeptídeo pd-l1 mutante |
| PT3283508T (pt) | 2015-04-17 | 2021-06-21 | Alpine Immune Sciences Inc | Proteínas imuno modulatórias com afinidades afináveis |
| EP3371208B8 (en) | 2015-11-02 | 2024-10-23 | Five Prime Therapeutics, Inc. | Cd80 extracellular domain polypeptides and their use in cancer treatment |
| IL310729A (en) | 2016-04-15 | 2024-04-01 | Alpine Immune Sciences Inc | Cd80 variant immunomodulatory proteins and uses thereof |
| AU2017266905B2 (en) | 2016-05-18 | 2022-12-15 | Albert Einstein College Of Medicine, Inc. | Variant PD-L1 polypeptides, T-cell modulatory multimeric polypeptides, and methods of use thereof |
| CA3019005A1 (en) | 2016-05-18 | 2017-11-23 | Cue Biopharma, Inc. | T-cell modulatory multimeric polypeptides and methods of use thereof |
| JP7250677B2 (ja) | 2016-12-22 | 2023-04-03 | キュー バイオファーマ， インコーポレイテッド | Ｔ細胞調節多量体ポリペプチド及びその使用方法 |
| US11851471B2 (en) | 2017-01-09 | 2023-12-26 | Cue Biopharma, Inc. | T-cell modulatory multimeric polypeptides and methods of use thereof |
| KR102619015B1 (ko) | 2017-03-15 | 2023-12-28 | 큐 바이오파마, 인크. | 면역 반응을 조절하는 방법 |
| IL268781B2 (en) | 2017-03-16 | 2025-09-01 | Alpine Immune Sciences Inc | Cd80 variant immunomodulatory proteins and uses thereof |
| EA201992586A1 (ru) | 2017-04-28 | 2020-03-03 | Файв Прайм Терапьютикс, Инк. | Способы лечения с помощью полипептидов внеклеточного домена cd80 |
| CN111278864A (zh) * | 2017-09-07 | 2020-06-12 | 库尔生物制药有限公司 | 抗原呈递多肽及其使用方法 |
| CA3074839A1 (en) * | 2017-09-07 | 2019-03-14 | Cue Biopharma, Inc. | T-cell modulatory multimeric polypeptide with conjugation sites and methods of use thereof |
| EP3737689A4 (en) | 2018-01-09 | 2021-12-01 | Cue Biopharma, Inc. | MULTIMER POLYPEPTIDES T-LYMPHOCYTE MODULATORS AND THEIR METHODS OF USE |
| EP3897690A4 (en) * | 2018-12-19 | 2022-09-28 | Cue Biopharma, Inc. | T LYMPHOCYTE MODULATOR MULTIMERIC POLYPEPTIDES HAVING CONJUGATION SITES AND METHODS OF USE THEREOF |
| WO2020181272A1 (en) * | 2019-03-06 | 2020-09-10 | Cue Biopharma, Inc. | Antigen-presenting polypeptides with chemical conjugation sites and methods of use thereof |
| WO2020243315A1 (en) * | 2019-05-29 | 2020-12-03 | Cue Biopharma, Inc. | Multimeric t-cell modulatory polypeptides and methods of use thereof |
| CA3146591A1 (en) * | 2019-09-20 | 2021-03-25 | Ronald D. Seidel Iii | T-cell modulatory polypeptides and methods of use thereof |
| BR112022007749A2 (pt) | 2019-10-23 | 2022-07-05 | Cue Biopharma Inc | Construto de tgf-b, mascarado, complexo de tgf-b, heterodímero do complexo de tgf-b mascarado, um ou mais ácidos nucleicos, uso de um ou mais construtos ou complexos de tgf-b mascarados, composição, método de produção de um construto ou complexo de tgf-b mascarado e composição farmacêutica |
| WO2021178975A1 (en) * | 2020-03-06 | 2021-09-10 | Albert Einstein College Of Medicine | A method to generate chimeric antigen receptor (car) t-cells (car-t cells) from pathogen-specific cytotoxic lymphocytes to enable the subsequent in vivo modulation of their functional activity |
| US20240209061A1 (en) * | 2020-03-09 | 2024-06-27 | Pfizer Inc. | Fusion proteins and uses thereof |
| CA3169949A1 (en) | 2020-05-12 | 2021-11-18 | Cue Biopharma, Inc. | Multimeric t-cell modulatory polypeptides and methods of use thereof |
| EP4157349A4 (en) * | 2020-05-26 | 2024-07-17 | Cue Biopharma, Inc. | ANTIGEN-PRESENTING POLYPEPTIDE COMPLEXES AND ASSOCIATED METHODS OF USE |
| WO2021242937A2 (en) * | 2020-05-26 | 2021-12-02 | Cue Biopharma, Inc. | Antigen presenting polypeptide complexes and methods of use thereof |
| EP4182465A4 (en) * | 2020-07-14 | 2024-08-07 | Cue Biopharma, Inc. | T-CELL MODULATORY POLYPEPTIDES HAVING CONJUGATION SITES AND METHODS OF USE THEREOF |
| JP2023541366A (ja) | 2020-09-09 | 2023-10-02 | キュー バイオファーマ， インコーポレイテッド | １型真性糖尿病（ｔ１ｄ）を治療するためのｍｈｃクラスｉｉ ｔ細胞調節多量体ポリペプチド及びその使用方法 |
| WO2022226037A1 (en) * | 2021-04-21 | 2022-10-27 | Cue Biopharma, Inc. | Antigen presenting polypeptide complexes bearing tgf-beta and methods of use thereof |
| EP4346889A4 (en) * | 2021-05-26 | 2025-04-30 | Cue Biopharma, Inc. | Antigen-presenting polypeptide complexes and methods of using them |
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| CZ302870B6 (cs) * | 1998-04-07 | 2011-12-28 | Corixa Corporation | Polynukleotid, polypeptid, farmaceutický prostredek, vakcínový prostredek a jejich použití k lécbe a prevenci infekce tuberkulózou |
| BR112013033661A2 (pt) * | 2011-06-30 | 2017-01-24 | Genzyme Corp | inibidores de ativação de células t |
| CN102898504B (zh) * | 2012-10-23 | 2014-08-06 | 中国农业大学 | 抗氧化活性合成肽及其用途 |
| ES2767259T3 (es) * | 2014-06-18 | 2020-06-17 | Albert Einstein College Medicine | Polipéptidos syntac y usos de los mismos |
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| WO2017151818A2 (en) | 2017-09-08 |
| AU2017226269A1 (en) | 2018-09-06 |
| EP3423108A2 (en) | 2019-01-09 |
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| EP3423108A4 (en) | 2019-10-02 |
| AU2017226269B2 (en) | 2021-10-28 |
| CN109311945A (zh) | 2019-02-05 |
| WO2017151818A3 (en) | 2017-10-26 |
| US20230227530A1 (en) | 2023-07-20 |
| IL261401A (en) | 2018-10-31 |
| JP2019516665A (ja) | 2019-06-20 |
| CA3014458A1 (en) | 2017-09-08 |
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