JP2022515330A5 - - Google Patents

Info

Publication number
JP2022515330A5
JP2022515330A5 JP2021531831A JP2021531831A JP2022515330A5 JP 2022515330 A5 JP2022515330 A5 JP 2022515330A5 JP 2021531831 A JP2021531831 A JP 2021531831A JP 2021531831 A JP2021531831 A JP 2021531831A JP 2022515330 A5 JP2022515330 A5 JP 2022515330A5
Authority
JP
Japan
Prior art keywords
polypeptide
amino acid
acid sequence
tmmp
seq
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2021531831A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022515330A (ja
JP7549579B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2019/067575 external-priority patent/WO2020132297A1/en
Publication of JP2022515330A publication Critical patent/JP2022515330A/ja
Publication of JP2022515330A5 publication Critical patent/JP2022515330A5/ja
Application granted granted Critical
Publication of JP7549579B2 publication Critical patent/JP7549579B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2021531831A 2018-12-19 2019-12-19 多量体t細胞調節ポリペプチド及びその使用方法 Active JP7549579B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201862782167P 2018-12-19 2018-12-19
US62/782,167 2018-12-19
US201962814684P 2019-03-06 2019-03-06
US62/814,684 2019-03-06
PCT/US2019/067575 WO2020132297A1 (en) 2018-12-19 2019-12-19 Multimeric t-cell modulatory polypeptides and methods of use thereof

Publications (3)

Publication Number Publication Date
JP2022515330A JP2022515330A (ja) 2022-02-18
JP2022515330A5 true JP2022515330A5 (enExample) 2022-12-26
JP7549579B2 JP7549579B2 (ja) 2024-09-11

Family

ID=71100921

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021531831A Active JP7549579B2 (ja) 2018-12-19 2019-12-19 多量体t細胞調節ポリペプチド及びその使用方法

Country Status (18)

Country Link
US (2) US20220112252A1 (enExample)
EP (2) EP3897701B1 (enExample)
JP (1) JP7549579B2 (enExample)
KR (1) KR20210104673A (enExample)
CN (1) CN113286609B (enExample)
AU (1) AU2019404285B2 (enExample)
BR (1) BR112021011814A2 (enExample)
CA (1) CA3113100A1 (enExample)
DK (1) DK3897701T3 (enExample)
ES (1) ES3052836T3 (enExample)
IL (1) IL281505B2 (enExample)
MX (1) MX2021007287A (enExample)
MY (1) MY206813A (enExample)
PH (1) PH12021500027A1 (enExample)
SG (1) SG11202103863UA (enExample)
SI (1) SI3897701T1 (enExample)
TW (1) TWI856047B (enExample)
WO (1) WO2020132297A1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11201808552XA (en) * 2016-05-18 2018-10-30 Cue Biopharma Inc T-cell modulatory multimeric polypeptides and methods of use thereof
CN110325205B (zh) 2016-12-22 2023-08-15 库尔生物制药有限公司 T细胞调节性多聚体多肽及其使用方法
KR20240005989A (ko) 2017-03-15 2024-01-12 큐 바이오파마, 인크. 면역 반응을 조절하는 방법
WO2019051127A1 (en) 2017-09-07 2019-03-14 Cue Biopharma, Inc. MULTIMER MODULATOR POLYPEPTIDE OF LYMPHOCYTE T HAVING CONJUGATION SITES AND METHODS OF USE THEREOF
WO2021230638A1 (en) * 2020-05-12 2021-11-18 Lg Chem, Ltd. Multimeric t-cell modulatory polypeptides and methods of use thereof
IL296209A (en) 2020-05-12 2022-11-01 Cue Biopharma Inc Multimeric t-cell modulatory polypeptides and methods of using them
WO2022015880A2 (en) * 2020-07-14 2022-01-20 Cue Biopharma, Inc. T-cell modulatory polypeptides with conjugation sites and methods of use thereof
WO2022099157A1 (en) * 2020-11-06 2022-05-12 Cue Biopharma, Inc. Antigen presenting polypeptide complexes and methods of use thereof
EP4308143A4 (en) * 2021-03-19 2025-06-04 Cue Biopharma, Inc. T-cell modulatory polypeptides and methods of use thereof
CN117222421A (zh) * 2021-03-19 2023-12-12 Cue生物制药股份有限公司 T细胞调节多肽和其使用方法
WO2023081718A1 (en) * 2021-11-04 2023-05-11 Cue Biopharma, Inc. Multimeric t-cell modulatory polypeptides and methods of use thereof
CN114805538B (zh) * 2022-05-20 2023-06-09 广州智瓴生物医药有限公司 一种增强til功效的培养方法
WO2026125765A1 (en) 2024-12-13 2026-06-18 Immunoscape Pte. Ltd. Combination therapy

Family Cites Families (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4235871A (en) 1978-02-24 1980-11-25 Papahadjopoulos Demetrios P Method of encapsulating biologically active materials in lipid vesicles
US4501728A (en) 1983-01-06 1985-02-26 Technology Unlimited, Inc. Masking of liposomes from RES recognition
US4837028A (en) 1986-12-24 1989-06-06 Liposome Technology, Inc. Liposomes with enhanced circulation time
US5585362A (en) 1989-08-22 1996-12-17 The Regents Of The University Of Michigan Adenovirus vectors for gene therapy
ATE237694T1 (de) 1991-08-20 2003-05-15 Us Gov Health & Human Serv Adenovirus vermittelter gentransfer in den gastrointestinaltrakt
US5252479A (en) 1991-11-08 1993-10-12 Research Corporation Technologies, Inc. Safe vector for gene therapy
FR2688514A1 (fr) 1992-03-16 1993-09-17 Centre Nat Rech Scient Adenovirus recombinants defectifs exprimant des cytokines et medicaments antitumoraux les contenant.
EP0673431A1 (en) 1992-12-03 1995-09-27 Genzyme Corporation Gene therapy for cystic fibrosis
EP0705344B8 (en) 1993-06-24 2006-05-10 Advec Inc. Adenovirus vectors for gene therapy
DE69435223D1 (de) 1993-10-25 2009-09-03 Canji Inc Rekombinanter Adenoviren-Vektor und Verfahren zur Verwendung
US7078387B1 (en) 1998-12-28 2006-07-18 Arch Development Corp. Efficient and stable in vivo gene transfer to cardiomyocytes using recombinant adeno-associated virus vectors
US6287860B1 (en) 2000-01-20 2001-09-11 Isis Pharmaceuticals, Inc. Antisense inhibition of MEKK2 expression
US7855279B2 (en) 2005-09-27 2010-12-21 Amunix Operating, Inc. Unstructured recombinant polymers and uses thereof
CA2644712C (en) 2006-03-06 2016-09-13 Amunix, Inc. Unstructured recombinant polymers and uses thereof
CA2695374A1 (en) 2007-08-15 2009-02-19 Amunix, Inc. Compositions and methods for modifying properties of biologically active polypeptides
MX356367B (es) 2008-12-09 2018-05-25 Genentech Inc Anticuerpos anti-pd-l1 y su uso para mejorar la funcion de celulas t.
DK3178835T3 (da) 2009-02-03 2019-06-24 Amunix Pharmaceuticals Inc Forlængede rekombinante polypeptider og sammensætninger omfattende samme
EP3279215B1 (en) 2009-11-24 2020-02-12 MedImmune Limited Targeted binding agents against b7-h1
US9205144B2 (en) 2011-06-03 2015-12-08 Dana-Farber Cancer Institute, Inc. Identification of conserved peptide blocks in homologous polypeptides
LT2945647T (lt) * 2013-01-15 2021-02-25 Memorial Sloan Kettering Cancer Center Imunogeniniai wt-1 peptidai ir jų panaudojimo būdai
JP6652932B2 (ja) * 2014-06-18 2020-02-26 アルバート アインシュタイン カレッジ オブ メディシン synTacポリペプチド及びその使用
ES2774380T3 (es) * 2014-08-29 2020-07-20 Hoffmann La Roche Politerapia de inmunocitocinas de variante de IL-2 dirigida a tumor y anticuerpos frente a PD-L1 humano
SG11201707182WA (en) 2015-03-05 2017-10-30 Hutchinson Fred Cancer Res Immunomodulatory fusion proteins and uses thereof
MX383464B (es) 2015-07-13 2025-03-14 Cytomx Therapeutics Inc Anticuerpos anti-pd-1, anticuerpos anti-pd-1 activables, y métodos de uso de los mismos.
HUE059694T2 (hu) * 2015-11-20 2022-12-28 Memorial Sloan Kettering Cancer Center Készítmény rák kezelésére
SG11201808552XA (en) * 2016-05-18 2018-10-30 Cue Biopharma Inc T-cell modulatory multimeric polypeptides and methods of use thereof
CN110325205B (zh) * 2016-12-22 2023-08-15 库尔生物制药有限公司 T细胞调节性多聚体多肽及其使用方法
KR20240005989A (ko) * 2017-03-15 2024-01-12 큐 바이오파마, 인크. 면역 반응을 조절하는 방법
US11725210B2 (en) * 2017-03-17 2023-08-15 Fred Hutchinson Cancer Center Immunomodulatory fusion proteins and uses thereof
MX2020002596A (es) * 2017-09-07 2020-07-20 Cue Biopharma Inc Polipeptidos moduladores de linfocitos t multimericos y metodos de uso de estos.
WO2019051127A1 (en) * 2017-09-07 2019-03-14 Cue Biopharma, Inc. MULTIMER MODULATOR POLYPEPTIDE OF LYMPHOCYTE T HAVING CONJUGATION SITES AND METHODS OF USE THEREOF
EP3897690A4 (en) * 2018-12-19 2022-09-28 Cue Biopharma, Inc. T LYMPHOCYTE MODULATOR MULTIMERIC POLYPEPTIDES HAVING CONJUGATION SITES AND METHODS OF USE THEREOF
WO2020132366A2 (en) * 2018-12-19 2020-06-25 Cue Biopharma, Inc. T-cell modulatory multimeric polypeptides with conjugation sites and methods of use thereof
WO2020132365A2 (en) * 2018-12-19 2020-06-25 Cue Biopharma, Inc. T-cell modulatory multimeric polypeptides with conjugation sites and methods of use thereof
EP4030897A4 (en) * 2019-09-20 2023-10-18 Cue Biopharma, Inc. T-cell modulatory polypeptides and methods of use thereof
US20230117521A1 (en) * 2020-03-25 2023-04-20 Cue Biopharma, Inc. T-cell modulatory multimeric polypeptides with conjugation sites and methods of use thereof
IL296209A (en) * 2020-05-12 2022-11-01 Cue Biopharma Inc Multimeric t-cell modulatory polypeptides and methods of using them
EP4308143A4 (en) * 2021-03-19 2025-06-04 Cue Biopharma, Inc. T-cell modulatory polypeptides and methods of use thereof

Similar Documents

Publication Publication Date Title
JP2022536581A5 (enExample)
JP2019512222A5 (enExample)
JP7270001B2 (ja) Mhcクラスii拘束性mage-a3を認識するt細胞受容体
JP7573075B2 (ja) 変異型p53を認識するt細胞受容体
JP2021500855A5 (enExample)
JP7385566B2 (ja) 突然変異rasに対するhlaクラスi拘束性t細胞受容体
Kelly et al. A new human HLA class II-related locus, DM
IL272085B2 (en) Multimeric t-cell modulatory polypeptides and methods of use thereof
JP2020511949A5 (enExample)
JP7635165B2 (ja) p53におけるR175H又はY220C変異を認識するT細胞受容体
IL308851B2 (en) T-cell modulatory multimeric polypeptides and methods of use thereof
JP2022515331A5 (enExample)
JP2021191265A5 (enExample)
JP2023526723A5 (enExample)
WO2020082130A1 (en) T-cell receptors and uses thereof
JP2017519491A5 (enExample)
JP2015535816A5 (enExample)
JP2010527919A5 (enExample)
RS55609B1 (sr) Fc fuzioni proteini koji sadrže nove linkere ili aranžmane
JP7735285B2 (ja) G12v突然変異rasに対するhlaクラスi拘束性t細胞受容体
JP2022522405A5 (enExample)
JP7742354B2 (ja) G12v変異を有するrasに対するhlaクラスii拘束性t細胞受容体
CN111892661A (zh) 一种嵌合抗原受体及其在制备治疗肿瘤的产品中的应用
JP2023541366A5 (enExample)
CN114901684A (zh) 粒细胞集落刺激因子受体(g-csfr)的经修饰胞外结构域和结合其的细胞因子