JP2019513726A5 - - Google Patents
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- JP2019513726A5 JP2019513726A5 JP2018552076A JP2018552076A JP2019513726A5 JP 2019513726 A5 JP2019513726 A5 JP 2019513726A5 JP 2018552076 A JP2018552076 A JP 2018552076A JP 2018552076 A JP2018552076 A JP 2018552076A JP 2019513726 A5 JP2019513726 A5 JP 2019513726A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- amino acid
- acid sequence
- cdr
- sequence seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021147485A JP7326393B2 (ja) | 2016-04-04 | 2021-09-10 | 抗補体Bb因子抗体及びその使用 |
| JP2023126155A JP2023139289A (ja) | 2016-04-04 | 2023-08-02 | 抗補体Bb因子抗体及びその使用 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662317897P | 2016-04-04 | 2016-04-04 | |
| US62/317,897 | 2016-04-04 | ||
| PCT/US2017/025784 WO2017176651A1 (en) | 2016-04-04 | 2017-04-03 | Anti-complement factor bb antibodies and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021147485A Division JP7326393B2 (ja) | 2016-04-04 | 2021-09-10 | 抗補体Bb因子抗体及びその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019513726A JP2019513726A (ja) | 2019-05-30 |
| JP2019513726A5 true JP2019513726A5 (enExample) | 2020-05-07 |
| JP6967528B2 JP6967528B2 (ja) | 2021-11-17 |
Family
ID=60000646
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018552076A Active JP6967528B2 (ja) | 2016-04-04 | 2017-04-03 | 抗補体Bb因子抗体及びその使用 |
| JP2021147485A Active JP7326393B2 (ja) | 2016-04-04 | 2021-09-10 | 抗補体Bb因子抗体及びその使用 |
| JP2023126155A Pending JP2023139289A (ja) | 2016-04-04 | 2023-08-02 | 抗補体Bb因子抗体及びその使用 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021147485A Active JP7326393B2 (ja) | 2016-04-04 | 2021-09-10 | 抗補体Bb因子抗体及びその使用 |
| JP2023126155A Pending JP2023139289A (ja) | 2016-04-04 | 2023-08-02 | 抗補体Bb因子抗体及びその使用 |
Country Status (23)
| Country | Link |
|---|---|
| US (3) | US10934347B2 (enExample) |
| EP (1) | EP3452510A4 (enExample) |
| JP (3) | JP6967528B2 (enExample) |
| KR (2) | KR102673420B1 (enExample) |
| CN (2) | CN109563158B (enExample) |
| AU (2) | AU2017246794B2 (enExample) |
| BR (1) | BR112018070357A2 (enExample) |
| CA (1) | CA3019332A1 (enExample) |
| CL (1) | CL2018002810A1 (enExample) |
| CO (1) | CO2018010827A2 (enExample) |
| CR (1) | CR20180529A (enExample) |
| DO (1) | DOP2018000219A (enExample) |
| EA (1) | EA201892225A1 (enExample) |
| EC (1) | ECSP18082302A (enExample) |
| IL (3) | IL311675A (enExample) |
| MA (1) | MA44878A (enExample) |
| MX (2) | MX2018012176A (enExample) |
| MY (1) | MY194603A (enExample) |
| PE (1) | PE20190209A1 (enExample) |
| PH (1) | PH12018502137A1 (enExample) |
| SG (1) | SG11201808525UA (enExample) |
| TN (1) | TN2018000341A1 (enExample) |
| WO (1) | WO2017176651A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2011282579B2 (en) | 2010-07-28 | 2014-10-23 | Gliknik Inc. | Fusion proteins of natural human protein fragments to create orderly multimerized immunoglobulin Fc compositions |
| FI3325011T6 (fi) | 2015-07-24 | 2023-05-11 | Ihmisen proteiinifragmenttien fuusioproteiineja järjestyksenmukaisesti multimerisoitujen, paremmin komplementtia sitovien immunoglobuliini-fc-koostumusten muodostamiseksi | |
| US10934347B2 (en) | 2016-04-04 | 2021-03-02 | Genzyme Corporation | Anti-complement factor BB antibodies and uses thereof |
| KR102729723B1 (ko) | 2016-12-09 | 2024-11-15 | 글리크닉 인코포레이티드 | 다합체화 스트라도머인 gl-2045의 제조 최적화 |
| JP7519774B2 (ja) * | 2016-12-09 | 2024-07-22 | グリックニック インコーポレイテッド | 多価fc化合物を用いる炎症性疾患の治療方法 |
| US11690919B2 (en) * | 2017-01-17 | 2023-07-04 | The Texas A&M University System | Endolysosomal targeting conjugates for improved delivery of cargo molecules to the endolysosomal compartment of target cells |
| US11192944B2 (en) | 2017-10-11 | 2021-12-07 | Bioverativ Usa Inc. | Methods of inducing complement activity |
| EP3728568A4 (en) | 2017-12-19 | 2021-10-06 | The University of North Carolina at Chapel Hill | METHODS AND COMPOSITIONS FOR DELIVERING VIRAL VECTORS BY THE BLOOD-BRAIN BARRIER |
| JP2022540768A (ja) * | 2019-06-27 | 2022-09-20 | ヴェルソー セラピューティクス, インコーポレイテッド | 骨髄細胞炎症性表現型を調節するための抗cd53組成物及び方法、ならびにその使用 |
| BR112022000739A2 (pt) * | 2019-07-17 | 2022-04-12 | Gemini Therapeutics Sub Inc | Anticorpos de potencialização de fator h e usos dos mesmos |
| US20230050339A1 (en) * | 2020-02-18 | 2023-02-16 | Children's Hospital Medical Center | Compositions and methods for treating liver disease |
| WO2021216458A1 (en) * | 2020-04-20 | 2021-10-28 | Genzyme Corporation | Humanized anti-complement factor bb antibodies and uses thereof |
| JP7787164B2 (ja) | 2020-09-23 | 2025-12-16 | アキリオン ファーマシューティカルズ, インコーポレーテッド | 補体媒介性障害の治療のための医薬化合物 |
Family Cites Families (59)
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| US4866132A (en) | 1986-04-17 | 1989-09-12 | The Research Foundation Of State University Of New York | Novel radiopaque barium polymer complexes, compositions of matter and articles prepared therefrom |
| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| AU612370B2 (en) | 1987-05-21 | 1991-07-11 | Micromet Ag | Targeted multifunctional proteins |
| US5256334A (en) | 1988-09-08 | 1993-10-26 | The Research Foundation Of The State University Of New York | Homogeneous radiopaque polymer-organobismuth composites |
| DE3920358A1 (de) | 1989-06-22 | 1991-01-17 | Behringwerke Ag | Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung |
| US5585362A (en) | 1989-08-22 | 1996-12-17 | The Regents Of The University Of Michigan | Adenovirus vectors for gene therapy |
| US5595732A (en) | 1991-03-25 | 1997-01-21 | Hoffmann-La Roche Inc. | Polyethylene-protein conjugates |
| DE69233482T2 (de) | 1991-05-17 | 2006-01-12 | Merck & Co., Inc. | Verfahren zur Verminderung der Immunogenität der variablen Antikörperdomänen |
| AU663725B2 (en) | 1991-08-20 | 1995-10-19 | United States Of America, Represented By The Secretary, Department Of Health And Human Services, The | Adenovirus mediated transfer of genes to the gastrointestinal tract |
| ATE181571T1 (de) | 1991-09-23 | 1999-07-15 | Medical Res Council | Methoden zur herstellung humanisierter antikörper |
| US5252479A (en) | 1991-11-08 | 1993-10-12 | Research Corporation Technologies, Inc. | Safe vector for gene therapy |
| JPH07501451A (ja) | 1991-11-25 | 1995-02-16 | エンゾン・インコーポレイテッド | 多価抗原結合タンパク質 |
| FR2688514A1 (fr) | 1992-03-16 | 1993-09-17 | Centre Nat Rech Scient | Adenovirus recombinants defectifs exprimant des cytokines et medicaments antitumoraux les contenant. |
| JPH08503855A (ja) | 1992-12-03 | 1996-04-30 | ジェンザイム・コーポレイション | 嚢胞性線維症に対する遺伝子治療 |
| US5346981A (en) | 1993-01-13 | 1994-09-13 | Miles Inc. | Radiopaque polyurethanes |
| CA2115811A1 (en) | 1993-02-17 | 1994-08-18 | Claus Krebber | A method for in vivo selection of ligand-binding proteins |
| ES2249761T3 (es) | 1993-06-24 | 2006-04-01 | Advec Inc. | Vectores de adenovirus para terapia genica. |
| SK283703B6 (sk) | 1993-10-25 | 2003-12-02 | Canji, Inc. | Rekombinantný adenovírusový vektor a jeho použitie |
| US5643575A (en) | 1993-10-27 | 1997-07-01 | Enzon, Inc. | Non-antigenic branched polymer conjugates |
| KR100551104B1 (ko) | 1994-12-09 | 2006-02-09 | 임페리얼 컬리지 이노베이션스 리미티드 | 유전자의 동정 |
| AU4188196A (en) | 1994-12-22 | 1996-07-10 | Nissan Chemical Industries Ltd. | Organobismuth derivatives and process for producing the same |
| US5670477A (en) | 1995-04-20 | 1997-09-23 | Joseph F. Poduslo | Method to enhance permeability of the blood/brain blood/nerve bariers to therapeutic agents |
| AU728657B2 (en) | 1996-03-18 | 2001-01-18 | Board Of Regents, The University Of Texas System | Immunoglobulin-like domains with increased half-lives |
| JP4162267B2 (ja) | 1996-08-27 | 2008-10-08 | カイロン コーポレイション | Neisseria meningitidis血清型B複合糖質およびその使用法 |
| WO1998023289A1 (en) | 1996-11-27 | 1998-06-04 | The General Hospital Corporation | MODULATION OF IgG BINDING TO FcRn |
| US6080849A (en) | 1997-09-10 | 2000-06-27 | Vion Pharmaceuticals, Inc. | Genetically modified tumor-targeted bacteria with reduced virulence |
| AR014621A1 (es) | 1997-12-12 | 2001-03-28 | Macromed Inc | Un poli (etilenglicol) con forma de estrella, heterofuncional, biocompatible, metodo para su obtencion y metodo para conjugarlo con una proteina |
| US6737056B1 (en) | 1999-01-15 | 2004-05-18 | Genentech, Inc. | Polypeptide variants with altered effector function |
| PT1355919E (pt) | 2000-12-12 | 2011-03-02 | Medimmune Llc | Moléculas com semivida longa, composições que as contêm e suas utilizações |
| GB0105924D0 (en) | 2001-03-09 | 2001-04-25 | Microscience Ltd | Promoter |
| AU2005212369B2 (en) | 2004-02-10 | 2011-06-23 | Musc Foundation For Research Development | Inhibition of factor B, the alternative complement pathway and methods related thereto |
| KR101699142B1 (ko) | 2004-06-18 | 2017-01-23 | 암브룩스, 인코포레이티드 | 신규 항원-결합 폴리펩티드 및 이의 용도 |
| US20090016959A1 (en) | 2005-02-18 | 2009-01-15 | Richard Beliveau | Delivery of antibodies to the central nervous system |
| US8741260B2 (en) | 2005-10-07 | 2014-06-03 | Armagen Technologies, Inc. | Fusion proteins for delivery of GDNF to the CNS |
| HUE026423T2 (en) | 2005-11-04 | 2016-05-30 | Genentech Inc | Use of complement biosynthetic pathway inhibitors for treating eye diseases |
| MX2008007682A (es) | 2005-12-20 | 2008-10-23 | Sbi Biotech Co Ltd | Anticuerpo anti-ilt7. |
| CN101970002B (zh) | 2007-08-27 | 2016-05-18 | 诺福麦德治疗学股份有限公司 | 用因子Bb特异性抗体抑制补体活化的方法 |
| BRPI0820343A2 (pt) * | 2007-11-08 | 2017-08-22 | Genentech Inc | Anticorpos de antifator b e seus usos |
| WO2009082624A2 (en) | 2007-12-10 | 2009-07-02 | Zymogenetics, Inc. | Antagonists of il-17a, il-17f, and il-23 and methods of using the same |
| BRPI0923283A2 (pt) | 2008-12-05 | 2017-06-06 | Angiochem Inc | conjugados terapêuticos de peptídeo e usos dos mesmos |
| US8784819B2 (en) | 2009-09-29 | 2014-07-22 | Ibio Inc. | Influenza hemagglutinin antibodies, compositions and related methods |
| HK1199405A1 (en) | 2011-10-27 | 2015-07-03 | Nkt治疗公司 | Humanized antibodies to inkt |
| EP3093294A1 (en) * | 2012-02-24 | 2016-11-16 | Stemcentrx, Inc. | Dll3 modulators and methods of use |
| JP6244350B2 (ja) * | 2012-04-03 | 2017-12-06 | ノーベルメッド セラピューティクス インコーポレイテッド. | ヒト化およびキメラ抗因子Bb抗体、ならびにその使用 |
| WO2014044793A2 (en) | 2012-09-20 | 2014-03-27 | Max-Delbrück-Centrum für Molekulare Medizin | Cd22-binding peptides |
| CA2889197A1 (en) * | 2012-11-02 | 2014-05-08 | True North Therapeutics, Inc. | Anti-complement c1s antibodies and uses thereof |
| RU2019109456A (ru) | 2013-02-22 | 2019-04-10 | ЭББВИ СТЕМСЕНТРКС ЭлЭлСи | Новые конъюгаты антител и их применения |
| US9260527B2 (en) * | 2013-03-15 | 2016-02-16 | Sdix, Llc | Anti-human CXCR4 antibodies and methods of making same |
| US10035847B2 (en) * | 2013-10-02 | 2018-07-31 | The Rockefeller University | Amyloid protofibril antibodies and methods of use thereof |
| SG11201606983SA (en) | 2014-02-27 | 2016-09-29 | Allergan Inc | COMPLEMENT FACTOR Bb ANTIBODIES |
| CN114591433A (zh) | 2015-07-13 | 2022-06-07 | 西托姆克斯治疗公司 | 抗pd-1抗体、可活化抗pd-1抗体及其使用方法 |
| US10934347B2 (en) | 2016-04-04 | 2021-03-02 | Genzyme Corporation | Anti-complement factor BB antibodies and uses thereof |
| US11192944B2 (en) | 2017-10-11 | 2021-12-07 | Bioverativ Usa Inc. | Methods of inducing complement activity |
| WO2021216458A1 (en) | 2020-04-20 | 2021-10-28 | Genzyme Corporation | Humanized anti-complement factor bb antibodies and uses thereof |
-
2017
- 2017-04-03 US US16/091,447 patent/US10934347B2/en active Active
- 2017-04-03 BR BR112018070357-5A patent/BR112018070357A2/pt active Search and Examination
- 2017-04-03 IL IL311675A patent/IL311675A/en unknown
- 2017-04-03 TN TNP/2018/000341A patent/TN2018000341A1/en unknown
- 2017-04-03 IL IL262010A patent/IL262010B/en unknown
- 2017-04-03 CN CN201780029742.9A patent/CN109563158B/zh active Active
- 2017-04-03 AU AU2017246794A patent/AU2017246794B2/en active Active
- 2017-04-03 CR CR20180529A patent/CR20180529A/es unknown
- 2017-04-03 KR KR1020187031483A patent/KR102673420B1/ko active Active
- 2017-04-03 MY MYPI2018001682A patent/MY194603A/en unknown
- 2017-04-03 CN CN202210862505.3A patent/CN116790614A/zh active Pending
- 2017-04-03 WO PCT/US2017/025784 patent/WO2017176651A1/en not_active Ceased
- 2017-04-03 MA MA044878A patent/MA44878A/fr unknown
- 2017-04-03 SG SG11201808525UA patent/SG11201808525UA/en unknown
- 2017-04-03 IL IL295288A patent/IL295288B2/en unknown
- 2017-04-03 EA EA201892225A patent/EA201892225A1/ru unknown
- 2017-04-03 JP JP2018552076A patent/JP6967528B2/ja active Active
- 2017-04-03 MX MX2018012176A patent/MX2018012176A/es unknown
- 2017-04-03 PE PE2018001946A patent/PE20190209A1/es unknown
- 2017-04-03 CA CA3019332A patent/CA3019332A1/en active Pending
- 2017-04-03 KR KR1020247018546A patent/KR20240096672A/ko active Pending
- 2017-04-03 EP EP17779607.5A patent/EP3452510A4/en active Pending
-
2018
- 2018-10-03 CL CL2018002810A patent/CL2018002810A1/es unknown
- 2018-10-04 MX MX2023007149A patent/MX2023007149A/es unknown
- 2018-10-04 PH PH12018502137A patent/PH12018502137A1/en unknown
- 2018-10-04 DO DO2018000219A patent/DOP2018000219A/es unknown
- 2018-10-09 CO CONC2018/0010827A patent/CO2018010827A2/es unknown
- 2018-10-31 EC ECSENADI201882302A patent/ECSP18082302A/es unknown
-
2021
- 2021-01-19 US US17/151,860 patent/US11851482B2/en active Active
- 2021-09-10 JP JP2021147485A patent/JP7326393B2/ja active Active
-
2023
- 2023-08-02 JP JP2023126155A patent/JP2023139289A/ja active Pending
- 2023-11-08 US US18/504,416 patent/US20240228599A1/en active Pending
-
2024
- 2024-09-30 AU AU2024224000A patent/AU2024224000A1/en active Pending
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