ATE208629T1 - Neisseria meningitidis serogruppe b glykokonjugate und verfahren zu deren verwendung - Google Patents
Neisseria meningitidis serogruppe b glykokonjugate und verfahren zu deren verwendungInfo
- Publication number
- ATE208629T1 ATE208629T1 AT97936364T AT97936364T ATE208629T1 AT E208629 T1 ATE208629 T1 AT E208629T1 AT 97936364 T AT97936364 T AT 97936364T AT 97936364 T AT97936364 T AT 97936364T AT E208629 T1 ATE208629 T1 AT E208629T1
- Authority
- AT
- Austria
- Prior art keywords
- glycoconjugates
- neisseria meningitidis
- meningitidis serogroup
- vaccine formulations
- methods
- Prior art date
Links
- 241000588677 Neisseria meningitidis serogroup B Species 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 3
- 238000009472 formulation Methods 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 3
- 229960005486 vaccine Drugs 0.000 abstract 3
- 241000617590 Escherichia coli K1 Species 0.000 abstract 1
- 125000003047 N-acetyl group Chemical group 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 229920001542 oligosaccharide Polymers 0.000 abstract 1
- 150000002482 oligosaccharides Chemical class 0.000 abstract 1
- 125000005629 sialic acid group Chemical group 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/095—Neisseria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/831—Drug, bio-affecting and body treating compositions involving capsular polysaccharide of bacterium, e.g. polyribosyl ribitol phosphate
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/832—Drug, bio-affecting and body treating compositions involving bacterial toxin that has modified amino acid sequence
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/915—Therapeutic or pharmaceutical composition
- Y10S977/917—Vaccine
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2445496P | 1996-08-27 | 1996-08-27 | |
| PCT/US1997/013609 WO1998008543A1 (en) | 1996-08-27 | 1997-08-04 | Neisseria meningitidis serogroup b glycoconjugates and methods of using the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE208629T1 true ATE208629T1 (de) | 2001-11-15 |
Family
ID=21820678
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97936364T ATE208629T1 (de) | 1996-08-27 | 1997-08-04 | Neisseria meningitidis serogruppe b glykokonjugate und verfahren zu deren verwendung |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US6638513B2 (de) |
| EP (1) | EP0939647B2 (de) |
| JP (2) | JP4162267B2 (de) |
| AT (1) | ATE208629T1 (de) |
| CA (1) | CA2264735C (de) |
| DE (1) | DE69708318T3 (de) |
| DK (1) | DK0939647T4 (de) |
| ES (1) | ES2166097T5 (de) |
| PT (1) | PT939647E (de) |
| WO (1) | WO1998008543A1 (de) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0922059B1 (de) | 1996-08-27 | 2003-10-22 | Chiron Corporation | Meningokokkus b-epitop ausbildende monoklonale antikoerper und deren verwendung zur herstellung von impfstoffzusammenstellungen |
| JP4162267B2 (ja) * | 1996-08-27 | 2008-10-08 | カイロン コーポレイション | Neisseria meningitidis血清型B複合糖質およびその使用法 |
| EP0994723A1 (de) | 1997-06-24 | 2000-04-26 | Chiron Corporation | Verfahren um erwachsenen mit anti-meningokokken impfstoffzusammensetzungen zu immunizieren |
| GB9808866D0 (en) * | 1998-04-24 | 1998-06-24 | Smithkline Beecham Biolog | Novel compounds |
| ES2278446T3 (es) * | 1998-05-29 | 2007-08-01 | Novartis Vaccines And Diagnostics, Inc. | Vacunas combinadas b/c contra la meningitis. |
| WO2002080648A2 (en) * | 2001-04-05 | 2002-10-17 | Chiron Corporation | Mucosal boosting following parenteral priming |
| RU2322451C2 (ru) | 2001-04-17 | 2008-04-20 | Новартис Вэксинс Энд Диагностикс, Инк. | Молекулярные миметики эпитопов менингококка в, которые вызывают выработку функционально активных антител |
| GB0115176D0 (en) | 2001-06-20 | 2001-08-15 | Chiron Spa | Capular polysaccharide solubilisation and combination vaccines |
| MX339524B (es) | 2001-10-11 | 2016-05-30 | Wyeth Corp | Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica. |
| WO2003080678A1 (en) * | 2002-03-26 | 2003-10-02 | Chiron Srl | Modified saccharides having improved stability in water |
| DK1587537T3 (da) | 2003-01-30 | 2012-07-16 | Novartis Ag | Injicerbare vacciner mod multiple meningococ-serogrupper |
| GB0323103D0 (en) | 2003-10-02 | 2003-11-05 | Chiron Srl | De-acetylated saccharides |
| GB0408977D0 (en) | 2004-04-22 | 2004-05-26 | Chiron Srl | Immunising against meningococcal serogroup Y using proteins |
| US8148335B2 (en) | 2004-06-23 | 2012-04-03 | Children's Hospital & Research Center Oakland | De-N-acetyl sialic acid antigens, antibodies thereto, and methods of use in cancer therapy |
| WO2006002402A2 (en) * | 2004-06-23 | 2006-01-05 | Children's Hospital & Research Center At Oakland | Polysaccharide derivatives and uses in induction of an immune response |
| GB0611914D0 (en) * | 2006-06-15 | 2006-07-26 | Teti Giuseppe | Peptides that mimic non-human cross-reactive protective epitopes of the group Bmeningococcal capsulsar polysaccharide |
| AR064642A1 (es) | 2006-12-22 | 2009-04-15 | Wyeth Corp | Polinucleotido vector que lo comprende celula recombinante que comprende el vector polipeptido , anticuerpo , composicion que comprende el polinucleotido , vector , celula recombinante polipeptido o anticuerpo , uso de la composicion y metodo para preparar la composicion misma y preparar una composi |
| JP5523313B2 (ja) | 2007-07-03 | 2014-06-18 | チルドレンズ ホスピタル アンド リサーチ センター アット オークランド | ポリシアル酸誘導体、製造方法、ならびにがん抗原産生の増強およびターゲティングにおける使用 |
| JP5702600B2 (ja) * | 2007-07-03 | 2015-04-15 | チルドレンズ ホスピタル アンド リサーチ センター アット オークランド | オリゴシアル酸誘導体、製造方法および免疫学的使用 |
| AU2011288203A1 (en) * | 2010-03-18 | 2012-08-23 | Novartis Ag | Adjuvanted vaccines for serogroup B meningococcus |
| PL3831406T3 (pl) | 2010-08-23 | 2024-09-09 | Wyeth Llc | Stabilne preparaty antygenów rLP2086 Neisseria meningitidis |
| RU2546873C2 (ru) | 2010-09-10 | 2015-04-10 | УАЙТ ЭлЭлСи | Нелипидизированные варианты антигенов neisseria meningitidis orf2086 |
| PL2726511T3 (pl) | 2011-07-01 | 2019-12-31 | Ngm Biopharmaceuticals, Inc. | Kompozycje, zastosowania i sposoby leczenia zaburzeń oraz chorób metabolicznych |
| SA115360586B1 (ar) | 2012-03-09 | 2017-04-12 | فايزر انك | تركيبات لعلاج الالتهاب السحائي البكتيري وطرق لتحضيرها |
| MY167723A (en) | 2012-03-09 | 2018-09-21 | Pfizer | Neisseria meningitidis compositions and methods thereof |
| WO2014014821A1 (en) | 2012-07-19 | 2014-01-23 | Redwood Biosciences, Inc. | Antibody specific for cd22 and methods of use thereof |
| SI2885010T1 (sl) | 2012-08-16 | 2020-07-31 | Ipierian, Inc. | Metode zdravljenja tauopatije |
| CN104870475B (zh) | 2012-10-25 | 2019-11-08 | 美国比奥维拉迪维股份有限公司 | 抗补体C1s抗体和其用途 |
| CA2889197A1 (en) | 2012-11-02 | 2014-05-08 | True North Therapeutics, Inc. | Anti-complement c1s antibodies and uses thereof |
| EP3798228A1 (de) | 2012-11-28 | 2021-03-31 | NGM Biopharmaceuticals, Inc. | Zusammensetzungen und verfahren zur behandlung von stoffwechselstörungen und -erkrankungen |
| KR101980989B1 (ko) * | 2012-12-20 | 2019-05-21 | 화이자 인코포레이티드 | 당접합 방법 |
| SG11201504815QA (en) | 2012-12-27 | 2015-07-30 | Ngm Biopharmaceuticals Inc | Methods for modulating bile acid homeostasis and treatment of bile acid disorders and diseases |
| US9802987B2 (en) | 2013-03-08 | 2017-10-31 | Pfizer Inc. | Immunogenic fusion polypeptides |
| EA039554B1 (ru) | 2013-06-10 | 2022-02-09 | АйПИЕРИАН, ИНК. | Способ снижения уровней a40 и/или a42 в нервной клетке и/или во внеклеточной жидкости |
| EP4098276A1 (de) | 2013-09-08 | 2022-12-07 | Pfizer Inc. | Neisseria meningitidis-zusammensetzungen und verfahren dafür |
| WO2015081085A2 (en) | 2013-11-27 | 2015-06-04 | Ipierian, Inc. | Methods of treating a tauopathy |
| CN114129709A (zh) | 2014-10-23 | 2022-03-04 | 恩格姆生物制药公司 | 包含肽变异体的药物组合物及其使用方法 |
| US10888611B2 (en) | 2015-02-19 | 2021-01-12 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
| CA3003616C (en) | 2015-11-09 | 2020-07-28 | Ngm Biopharmaceuticals, Inc. | Methods for treatment of bile acid-related disorders |
| US10934347B2 (en) | 2016-04-04 | 2021-03-02 | Genzyme Corporation | Anti-complement factor BB antibodies and uses thereof |
| PE20191107A1 (es) | 2017-01-31 | 2019-08-26 | Pfizer | Composiciones de neisseria meningitidis y metodos respectivos |
| WO2021059181A1 (en) | 2019-09-27 | 2021-04-01 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4902506A (en) † | 1983-07-05 | 1990-02-20 | The University Of Rochester | Immunogenic conjugates |
| IT1187753B (it) * | 1985-07-05 | 1987-12-23 | Sclavo Spa | Coniugati glicoproteici ad attivita' immunogenica trivalente |
| US4727136A (en) † | 1985-10-01 | 1988-02-23 | Canadian Patents And Development Ltd. | Modified meningococcal group B polysaccharide for conjugate vaccine |
| NZ223009A (en) * | 1986-12-31 | 1990-06-26 | Nl Rivm Of Thoven | Oligosaccharides containing d-ribose d-ribitol and phosphate units mimicing haemophilus influenzae type b antigens |
| WO1991008772A1 (en) | 1989-12-14 | 1991-06-27 | National Research Council Of Canada | Improved meningococcal polysaccharide conjugate vaccine |
| US5153312A (en) * | 1990-09-28 | 1992-10-06 | American Cyanamid Company | Oligosaccharide conjugate vaccines |
| CA2059693C (en) * | 1991-01-28 | 2003-08-19 | Peter J. Kniskern | Polysaccharide antigens from streptococcus pneumoniae |
| CA2059692C (en) * | 1991-01-28 | 2004-11-16 | Peter J. Kniskern | Pneumoccoccal polysaccharide conjugate vaccine |
| US5354853A (en) * | 1993-03-12 | 1994-10-11 | Genzyme Corporation | Phospholipid-saccharide conjugates |
| GB9422096D0 (en) | 1994-11-02 | 1994-12-21 | Biocine Spa | Combined meningitis vaccine |
| US5811102A (en) * | 1995-06-07 | 1998-09-22 | National Research Council Of Canada | Modified meningococcal polysaccharide conjugate vaccines |
| WO1996040225A1 (en) * | 1995-06-07 | 1996-12-19 | Alberta Research Council | Immunogenic and immunostimulatory oligosaccharide compositions and methods of making and using them |
| JP4162267B2 (ja) * | 1996-08-27 | 2008-10-08 | カイロン コーポレイション | Neisseria meningitidis血清型B複合糖質およびその使用法 |
| EP0922059B1 (de) | 1996-08-27 | 2003-10-22 | Chiron Corporation | Meningokokkus b-epitop ausbildende monoklonale antikoerper und deren verwendung zur herstellung von impfstoffzusammenstellungen |
| EP0994723A1 (de) * | 1997-06-24 | 2000-04-26 | Chiron Corporation | Verfahren um erwachsenen mit anti-meningokokken impfstoffzusammensetzungen zu immunizieren |
| PT1630168E (pt) | 1997-08-27 | 2011-07-20 | Novartis Vaccines & Diagnostic | Compostos miméticos moleculares de péptidos de meningococos do serogrupo b |
-
1997
- 1997-08-04 JP JP51165698A patent/JP4162267B2/ja not_active Expired - Fee Related
- 1997-08-04 CA CA002264735A patent/CA2264735C/en not_active Expired - Fee Related
- 1997-08-04 ES ES97936364T patent/ES2166097T5/es not_active Expired - Lifetime
- 1997-08-04 DK DK97936364T patent/DK0939647T4/da active
- 1997-08-04 WO PCT/US1997/013609 patent/WO1998008543A1/en not_active Ceased
- 1997-08-04 PT PT97936364T patent/PT939647E/pt unknown
- 1997-08-04 AT AT97936364T patent/ATE208629T1/de active
- 1997-08-04 EP EP97936364A patent/EP0939647B2/de not_active Expired - Lifetime
- 1997-08-04 DE DE69708318T patent/DE69708318T3/de not_active Expired - Lifetime
- 1997-08-07 US US08/908,262 patent/US6638513B2/en not_active Expired - Fee Related
-
2003
- 2003-08-19 US US10/643,349 patent/US7169392B2/en not_active Expired - Fee Related
-
2008
- 2008-04-11 JP JP2008104151A patent/JP2008201793A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| WO1998008543A1 (en) | 1998-03-05 |
| US20020034518A1 (en) | 2002-03-21 |
| EP0939647A1 (de) | 1999-09-08 |
| US6638513B2 (en) | 2003-10-28 |
| ES2166097T3 (es) | 2002-04-01 |
| US7169392B2 (en) | 2007-01-30 |
| DE69708318T3 (de) | 2006-11-16 |
| CA2264735C (en) | 2008-01-29 |
| DK0939647T4 (da) | 2006-10-23 |
| DE69708318T2 (de) | 2002-07-11 |
| JP4162267B2 (ja) | 2008-10-08 |
| DE69708318D1 (de) | 2002-01-03 |
| EP0939647B2 (de) | 2006-07-12 |
| DK0939647T3 (da) | 2002-04-02 |
| CA2264735A1 (en) | 1998-03-05 |
| EP0939647B1 (de) | 2001-11-14 |
| JP2008201793A (ja) | 2008-09-04 |
| US20040052805A1 (en) | 2004-03-18 |
| HK1021145A1 (en) | 2000-06-02 |
| ES2166097T5 (es) | 2007-03-16 |
| PT939647E (pt) | 2002-04-29 |
| JP2001500540A (ja) | 2001-01-16 |
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